S0735109712013162_mmc1
... The ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2), is similar to ABCA1 in location and function and a common variant (rs2231142) reduces its transport capacity (5). Carriers of the A allele experience higher systemic exposure to rosuvastatin{Keskitalo, 2009 #1376} or atorvastatin(6), ...
... The ATP-binding cassette, sub-family G (WHITE), member 2 (ABCG2), is similar to ABCA1 in location and function and a common variant (rs2231142) reduces its transport capacity (5). Carriers of the A allele experience higher systemic exposure to rosuvastatin{Keskitalo, 2009 #1376} or atorvastatin(6), ...
Decoding DNA
... NAME: ______________ Decoding DNA Use your knowledge of transcription and translation to decode this secret message! STEP 1: “Build” a mRNA molecule that is complimentary to the DNA molecule, base pair by base pair. (REMEMBER: in RNA, adenine pairs with uracil) STEP 2: Determine the tRNA codons that ...
... NAME: ______________ Decoding DNA Use your knowledge of transcription and translation to decode this secret message! STEP 1: “Build” a mRNA molecule that is complimentary to the DNA molecule, base pair by base pair. (REMEMBER: in RNA, adenine pairs with uracil) STEP 2: Determine the tRNA codons that ...
Association study of the estrogen receptor I gene (ESR1) in anorexia
... have been sufficient to detect these effects. As there is a general tendency for initial studies to overestimate effect sizes, it is possible that associations were missed in the current study because of insufficient power to detect smaller effects. This could especially be the case for ESR1 rs72628 ...
... have been sufficient to detect these effects. As there is a general tendency for initial studies to overestimate effect sizes, it is possible that associations were missed in the current study because of insufficient power to detect smaller effects. This could especially be the case for ESR1 rs72628 ...
Analysis of the first polar body: preconception genetic
... 2C) and two were heterozygous due to crossing over (Figure 2, lower polar body; Figure 3, slot IB). The analysis of two polar bodies revealed no hybridization with either probe (Figure 3, slots 3B and 4B), indicating failed analyses. The light hybridization band of one of the heterozygous parents wi ...
... 2C) and two were heterozygous due to crossing over (Figure 2, lower polar body; Figure 3, slot IB). The analysis of two polar bodies revealed no hybridization with either probe (Figure 3, slots 3B and 4B), indicating failed analyses. The light hybridization band of one of the heterozygous parents wi ...
Chapter 3: Molecular Biology Problems
... Access “Molecules in 3-d” at this site http://intro.bio.umb.edu/MOOC/jsMol/ and click on the link for this problem “Molecular Bio C1”. This software has many useful features, so we will take some time now to describe its use in detail. This software allows you to get information from the image in se ...
... Access “Molecules in 3-d” at this site http://intro.bio.umb.edu/MOOC/jsMol/ and click on the link for this problem “Molecular Bio C1”. This software has many useful features, so we will take some time now to describe its use in detail. This software allows you to get information from the image in se ...
Standard Mutation Nomenclature in Molecular Diagnostics
... nomenclature based on coding DNA reference sequences and protein-level amino acid sequences requires prefixes “c.” and “p.,” respectively, as in Figure 2. Standard nomenclature based on genomic DNA reference sequences and RNA reference sequences is not shown. “Genomic DNA reference sequence” simply ...
... nomenclature based on coding DNA reference sequences and protein-level amino acid sequences requires prefixes “c.” and “p.,” respectively, as in Figure 2. Standard nomenclature based on genomic DNA reference sequences and RNA reference sequences is not shown. “Genomic DNA reference sequence” simply ...
MOLLECULAR BIOLOGY COURSE
... DNA is transferred to a similar molecule called RNA (ribonucleic acid) in the cell nucleus. Both RNA and DNA are made up of a chain of nucleotide bases, but they have slightly different chemical properties. The type of RNA that contains the information for making a protein is called messenger RNA (m ...
... DNA is transferred to a similar molecule called RNA (ribonucleic acid) in the cell nucleus. Both RNA and DNA are made up of a chain of nucleotide bases, but they have slightly different chemical properties. The type of RNA that contains the information for making a protein is called messenger RNA (m ...
Tuning Biphenyl Dioxygenase for Extended Substrate Specificity
... the production of the yellow meta-cleavage products. The biphenyl dioxygenase from the LB400 strain is capable of attacking a broad spectrum of PCB congeners, up to and including some hexachlorobiphenyls, but hardly degrades double-para-substituted congeners (Bedard et al., 1986; Bopp, 1986). Due to ...
... the production of the yellow meta-cleavage products. The biphenyl dioxygenase from the LB400 strain is capable of attacking a broad spectrum of PCB congeners, up to and including some hexachlorobiphenyls, but hardly degrades double-para-substituted congeners (Bedard et al., 1986; Bopp, 1986). Due to ...
3-23_Genetics
... we use to represent alleles? Alleles are different versions of the same gene/trait. We use CAPITAL and lowercase letters to represent them! ...
... we use to represent alleles? Alleles are different versions of the same gene/trait. We use CAPITAL and lowercase letters to represent them! ...
tG TG
... Section of chromosome (DNA) that codes for a specific trait. Reproductive cell. A diagram of the genetic history of an individual: can show how a trait is inherited over several generations of a family. (a genetic family tree) Any one of two or more alternative forms of a gene that may occur alterna ...
... Section of chromosome (DNA) that codes for a specific trait. Reproductive cell. A diagram of the genetic history of an individual: can show how a trait is inherited over several generations of a family. (a genetic family tree) Any one of two or more alternative forms of a gene that may occur alterna ...
Candidate genes and single nucleotide polymorphisms associated
... and 29 and the number of SNP on each chromosome was 4, 7, 1, 2, 2, 1, 7, and 1, respectively, indicating that majority of the significant SNP were located on BTA 1, 2, and 20. The chromosome BTA1 contains previously reported QTL for ADG and carcass weight (Komatsu et al., 2011), body length, hip hei ...
... and 29 and the number of SNP on each chromosome was 4, 7, 1, 2, 2, 1, 7, and 1, respectively, indicating that majority of the significant SNP were located on BTA 1, 2, and 20. The chromosome BTA1 contains previously reported QTL for ADG and carcass weight (Komatsu et al., 2011), body length, hip hei ...
Accounting for Non-Genetic Factors Improves the Power of eQTL
... other physiological and biological factors. In principle, when collecting gene expression data sets for eQTL, non-genetic factors should be controlled to be constant across all samples, but in practice this can only be achieved to a limited degree. Indeed, it is reasonable to expect that a substanti ...
... other physiological and biological factors. In principle, when collecting gene expression data sets for eQTL, non-genetic factors should be controlled to be constant across all samples, but in practice this can only be achieved to a limited degree. Indeed, it is reasonable to expect that a substanti ...
Leishmania donovani - Oxford Academic
... positioned above the DNA major groove, but do not directly interact with the DNA. The second lobe (also comprising two domains; the former resembling the core subdomain III of human topoisomerase I and the latter representing a short variable C-terminal domain) sits below the DNA, is composed of an ...
... positioned above the DNA major groove, but do not directly interact with the DNA. The second lobe (also comprising two domains; the former resembling the core subdomain III of human topoisomerase I and the latter representing a short variable C-terminal domain) sits below the DNA, is composed of an ...
NCEA Level 1 Science (90948) 2014
... lack of water limiting the plant’s growth. It is the combination of both the inheritable and non-inheritable factors that determines the phenotype. For example a plant might have two alleles coding for a tall plant, but if there is a lack of water the plant will not grow to its genetic potential. Va ...
... lack of water limiting the plant’s growth. It is the combination of both the inheritable and non-inheritable factors that determines the phenotype. For example a plant might have two alleles coding for a tall plant, but if there is a lack of water the plant will not grow to its genetic potential. Va ...
NCEA Level 1 Science (90948) 2014 Assessment Schedule
... lack of water limiting the plant’s growth. It is the combination of both the inheritable and non-inheritable factors that determines the phenotype. For example a plant might have two alleles coding for a tall plant, but if there is a lack of water the plant will not grow to its genetic potential. Va ...
... lack of water limiting the plant’s growth. It is the combination of both the inheritable and non-inheritable factors that determines the phenotype. For example a plant might have two alleles coding for a tall plant, but if there is a lack of water the plant will not grow to its genetic potential. Va ...
Specific oligonucleotide primers for detection of endoglucanase
... EN1R, were chosen that were predicted to specifically amplify a 1,311 bpDNA fragment of the B. Subtilis, G. stearothermophilus and P. campinasensis. The Genbank database (NCBI) search for complimentary sequences revealed 100 % homology between the primers and the gene encodes endo-b-1,4-glucanase of ...
... EN1R, were chosen that were predicted to specifically amplify a 1,311 bpDNA fragment of the B. Subtilis, G. stearothermophilus and P. campinasensis. The Genbank database (NCBI) search for complimentary sequences revealed 100 % homology between the primers and the gene encodes endo-b-1,4-glucanase of ...
Construction of plant BAC libraries This document
... 9. Run the gel using the following parameters: 5.0 v/cm, included angle = 120°, initial switch time = 3.0 sec, final switch time = 4.5 sec, run time = 13 hours, ramping = linear. 10. Using a ruler as a “straight-edge”, cut the gel with a scalpel as shown in FIGURE 2b. There will be seven gel pieces ...
... 9. Run the gel using the following parameters: 5.0 v/cm, included angle = 120°, initial switch time = 3.0 sec, final switch time = 4.5 sec, run time = 13 hours, ramping = linear. 10. Using a ruler as a “straight-edge”, cut the gel with a scalpel as shown in FIGURE 2b. There will be seven gel pieces ...
5.2 Dominant, Recessive, Heterozygous
... Reginald has one allele for green eyes, and one allele for brown eyes. He is heterozygous for eye color. ...
... Reginald has one allele for green eyes, and one allele for brown eyes. He is heterozygous for eye color. ...
DNA Pre-ConceptionStu - the Biology Scholars Program Wiki
... 4. The basic unit or monomer of DNA is composed of a(n): A. Lipid, a molecule of nitrate and one of four amino acids B. Lipid, a molecule of phosphate and one of four amino acids C. Protein, a molecule of nitrate and one of four nitrogen containing bases D. Sugar, a molecule of phosphate and one of ...
... 4. The basic unit or monomer of DNA is composed of a(n): A. Lipid, a molecule of nitrate and one of four amino acids B. Lipid, a molecule of phosphate and one of four amino acids C. Protein, a molecule of nitrate and one of four nitrogen containing bases D. Sugar, a molecule of phosphate and one of ...
Different Effects of PCR Inhibitors on Multiplex STR Assays
... wood from interior crime scenes can also contain inhibitors that interfere with the DNA polymerase’s activity. The impact of these contaminants on the multiplex STR assays can vary from attenuation to complete inhibition of the amplification process, resulting in partial STR profiles or profiles wit ...
... wood from interior crime scenes can also contain inhibitors that interfere with the DNA polymerase’s activity. The impact of these contaminants on the multiplex STR assays can vary from attenuation to complete inhibition of the amplification process, resulting in partial STR profiles or profiles wit ...
Identification of the Minus-Dominance Gene Ortholog in
... Such sexually activated, nonmixed cells were used for isolation of gamete RNA. Total RNA was isolated with the RNeasy Midi kit (QIAGEN, Hilden, Germany; protocol for heart, muscle, and skin tissue) after the cells had been homogenized with ceramic beads and a wash brush (Nozaki et al. 1997, 2006). F ...
... Such sexually activated, nonmixed cells were used for isolation of gamete RNA. Total RNA was isolated with the RNeasy Midi kit (QIAGEN, Hilden, Germany; protocol for heart, muscle, and skin tissue) after the cells had been homogenized with ceramic beads and a wash brush (Nozaki et al. 1997, 2006). F ...
Designing synthetic MLPA probes - MRC
... corresponding NG_sequence here: http://www.ncbi.nlm.nih.gov/refseq/rsg/browse/. N.b. NG_sequences also include intronic sequences. Nucleotide. The combination of LPO and RPO. DNA oligonucleotide which, when annealed to a complementary DNA sequence, can be used as starting point for extension by a po ...
... corresponding NG_sequence here: http://www.ncbi.nlm.nih.gov/refseq/rsg/browse/. N.b. NG_sequences also include intronic sequences. Nucleotide. The combination of LPO and RPO. DNA oligonucleotide which, when annealed to a complementary DNA sequence, can be used as starting point for extension by a po ...
SNP genotyping
SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. It is a form of genotyping, which is the measurement of more general genetic variation. SNPs are one of the most common types of genetic variation. An SNP is a single base pair mutation at a specific locus, usually consisting of two alleles (where the rare allele frequency is >1%). SNPs are found to be involved in the etiology of many human diseases and are becoming of particular interest in pharmacogenetics. Because SNPs are conserved during evolution, they have been proposed as markers for use in quantitative trait loci (QTL) analysis and in association studies in place of microsatellites. The use of SNPs is being extended in the HapMap project, which aims to provide the minimal set of SNPs needed to genotype the human genome. SNPs can also provide a genetic fingerprint for use in identity testing. The increase in interest in SNPs has been reflected by the furious development of a diverse range of SNP genotyping methods.