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Advances around technologies investigating mitochondrial function
... Insulin is one of the key hormones controlling mitochondrial function. Another key hormone is catecholamine, such as epinephrine. They stimulate general physiological processes and prepare the body for physical activity (fight-orflight response), which requires energy. Increases in heart rate, blood p ...
... Insulin is one of the key hormones controlling mitochondrial function. Another key hormone is catecholamine, such as epinephrine. They stimulate general physiological processes and prepare the body for physical activity (fight-orflight response), which requires energy. Increases in heart rate, blood p ...
Regulation of post-mortem glycolysis in ruminant muscle
... ATP (via myofibrillar ATPase). Because of the immediate and synchronised nature of contraction and its sensitivity to calcium, ATP-mediated calcium pumps are strategically located throughout the muscle cell on membranous vesicles that rapidly sequester calcium after such a twitch or contraction. Thes ...
... ATP (via myofibrillar ATPase). Because of the immediate and synchronised nature of contraction and its sensitivity to calcium, ATP-mediated calcium pumps are strategically located throughout the muscle cell on membranous vesicles that rapidly sequester calcium after such a twitch or contraction. Thes ...
11-Electrophoretic method for the separation of LDH
... (LDH). In skeletal muscle, where oxygen deprivation is common during exercise, the reaction is efficient and large amounts of lactate can be formed. In tissues that preferentially oxidize glucose aerobically to CO2 and water, such as cardiac muscle, the reaction is not efficient and pyruvate is pref ...
... (LDH). In skeletal muscle, where oxygen deprivation is common during exercise, the reaction is efficient and large amounts of lactate can be formed. In tissues that preferentially oxidize glucose aerobically to CO2 and water, such as cardiac muscle, the reaction is not efficient and pyruvate is pref ...
PDF
... 2002). These findings underscore the role of BM as a central scaffold for the developing nervous system. Spondins are a conserved family of ECM proteins that were originally identified as axon guidance factors in the vertebrate spinal cord (Klar et al., 1992). In vertebrates, spondins have contextde ...
... 2002). These findings underscore the role of BM as a central scaffold for the developing nervous system. Spondins are a conserved family of ECM proteins that were originally identified as axon guidance factors in the vertebrate spinal cord (Klar et al., 1992). In vertebrates, spondins have contextde ...
File - Doctorswriting
... C. Central venous pressure rises during negative pressure breathing D. Elevated central venous pressure occurs with expanded blood volume E. Peripheral venous pressure rises with increasing distance from the heart 48. Which of the following are true of CD4+ cells A. Are derived from bone marrow B. D ...
... C. Central venous pressure rises during negative pressure breathing D. Elevated central venous pressure occurs with expanded blood volume E. Peripheral venous pressure rises with increasing distance from the heart 48. Which of the following are true of CD4+ cells A. Are derived from bone marrow B. D ...
acetylcholine receptors in regenerating muscle
... of its surface area. At the synaptic site, basal lamina that projected into the junctional folds persists and is continuous with basal lamina of the synaptic cleft . The axon terminals are phagocytized by Schwann cells, which then occupy the position of the terminal on the synaptic portion of the my ...
... of its surface area. At the synaptic site, basal lamina that projected into the junctional folds persists and is continuous with basal lamina of the synaptic cleft . The axon terminals are phagocytized by Schwann cells, which then occupy the position of the terminal on the synaptic portion of the my ...
File - Doctorswriting
... C. Central venous pressure rises during negative pressure breathing D. Elevated central venous pressure occurs with expanded blood volume E. Peripheral venous pressure rises with increasing distance from the heart 48. Which of the following are true of CD4+ cells A. Are derived from bone marrow B. D ...
... C. Central venous pressure rises during negative pressure breathing D. Elevated central venous pressure occurs with expanded blood volume E. Peripheral venous pressure rises with increasing distance from the heart 48. Which of the following are true of CD4+ cells A. Are derived from bone marrow B. D ...
as a PDF
... biochemical and clinical efficacy of quinone supplementation in patients with primary69–72 and secondary (i.e., cardiomyopathy)56,73–75 coenzyme Q10 deficiency states and other forms of mitochondrial disorders.76 Given the preponderance of evidence supporting the therapeutic efficacy of coenzyme Q10 ...
... biochemical and clinical efficacy of quinone supplementation in patients with primary69–72 and secondary (i.e., cardiomyopathy)56,73–75 coenzyme Q10 deficiency states and other forms of mitochondrial disorders.76 Given the preponderance of evidence supporting the therapeutic efficacy of coenzyme Q10 ...
Insulin, Glucagon, and Diabetes Mellitus
... glucose is the only nutrient used by brain, retina, and germinal epithelium of gonads most of the glucose between meals is used in the brain glucose can exert high osmotic pressure (cellular dehydration), loss of glucose in urine, osmotic diuresis by the kidneys (loss of fluids and electrolytes), da ...
... glucose is the only nutrient used by brain, retina, and germinal epithelium of gonads most of the glucose between meals is used in the brain glucose can exert high osmotic pressure (cellular dehydration), loss of glucose in urine, osmotic diuresis by the kidneys (loss of fluids and electrolytes), da ...
Protein composition and function of red and white skeletal - AJP-Cell
... fast isoforms of contractile proteins, whereas red muscle has greater abundance of contractile protein slow isoforms and higher oxidative enzyme content (16, 38, 51). The larger oxidative capacity in red muscle is due, at least in part, to a two- to threefold greater mitochondrial content compared w ...
... fast isoforms of contractile proteins, whereas red muscle has greater abundance of contractile protein slow isoforms and higher oxidative enzyme content (16, 38, 51). The larger oxidative capacity in red muscle is due, at least in part, to a two- to threefold greater mitochondrial content compared w ...
Regulation of myocardial contractility 1958–1983: An Odyssey
... These controversies focused on three issues: I) the validity of the extrapolations of velocity measurements made at various muscle loads to the shortening velocity at zero load (V maJ (25). 2) the ability of such extrapolated values for V max to serve as quantitative measurements of myocardial contr ...
... These controversies focused on three issues: I) the validity of the extrapolations of velocity measurements made at various muscle loads to the shortening velocity at zero load (V maJ (25). 2) the ability of such extrapolated values for V max to serve as quantitative measurements of myocardial contr ...
Document
... at the MTJ, there have been no reports of actual failure occurring in vivo16-20. By mapping analysis and mutation detection we have shown that sap is mutated at the zebrafish orthologue of the human Duchenne muscular dystrophy locus which encode zf-dystrophin. This finding therefore reveals a novel ...
... at the MTJ, there have been no reports of actual failure occurring in vivo16-20. By mapping analysis and mutation detection we have shown that sap is mutated at the zebrafish orthologue of the human Duchenne muscular dystrophy locus which encode zf-dystrophin. This finding therefore reveals a novel ...
The muscle fiber type–fiber size paradox: hypertrophy or oxidative
... Tuberous sclerosis complex-2 Vascular endothelial growth factor Maximum rate of oxygen consumption Vacuolar protein sorting mutant 34 ...
... Tuberous sclerosis complex-2 Vascular endothelial growth factor Maximum rate of oxygen consumption Vacuolar protein sorting mutant 34 ...
Document
... subjects who also have high LDL cholesterol * Decision for treatment of high LDL before elevated triglyceride is based on clinical trial data indicating safety as well as efficacy of the available agents. ...
... subjects who also have high LDL cholesterol * Decision for treatment of high LDL before elevated triglyceride is based on clinical trial data indicating safety as well as efficacy of the available agents. ...
Carbohydrate Metabolism Glucose Metabolism Oxidation of Glucose
... a carbohydrate–rich diet ) , and at that concentration liver competes with other tissue for glucose and the excess glucose preferentially taken into liver where it can be stored as glycogen . 2. Hexokinase is inhibited allosterically by high levels of its product glucose-6-p . But glucokinase is not ...
... a carbohydrate–rich diet ) , and at that concentration liver competes with other tissue for glucose and the excess glucose preferentially taken into liver where it can be stored as glycogen . 2. Hexokinase is inhibited allosterically by high levels of its product glucose-6-p . But glucokinase is not ...
Smooth Muscle - Collin College
... The mechanism of many of the actions of NO involves the formation of cGMP. When NO is formed it readily diffuses out of the cell and into adjacent cells where is binds to soluble guanylyl cyclase. This enzyme is similar to adenylate cyclase but not coupled to Gproteins. When activated by NO, it prod ...
... The mechanism of many of the actions of NO involves the formation of cGMP. When NO is formed it readily diffuses out of the cell and into adjacent cells where is binds to soluble guanylyl cyclase. This enzyme is similar to adenylate cyclase but not coupled to Gproteins. When activated by NO, it prod ...
Important metabolic pathways in poultry embryos prior to hatch
... During the incubation period, the avian embryo does not invest much metabolic resources into gut development until the end of the incubation period when rapid visceral growth and maturation occurs (Uni et al., 2003; Gilbert et al., 2007). The sooner the intestinal tract achieves its functional capac ...
... During the incubation period, the avian embryo does not invest much metabolic resources into gut development until the end of the incubation period when rapid visceral growth and maturation occurs (Uni et al., 2003; Gilbert et al., 2007). The sooner the intestinal tract achieves its functional capac ...
factors that influence regeneration of the neuromuscular junction
... laboratory that were aimed at determining what structures within muscle influence regeneration of the neuromuscular junction. The findings demonstrate that factors which play a role in re-establishing the junction after damage to nerve and muscle are associated with the extracellular components of t ...
... laboratory that were aimed at determining what structures within muscle influence regeneration of the neuromuscular junction. The findings demonstrate that factors which play a role in re-establishing the junction after damage to nerve and muscle are associated with the extracellular components of t ...
R-lipoic acid inhibits mammalian pyruvate
... Racemic LA (rac-LA) has shown promise in treating diabetic polyneuropathy, and some studies suggest that it improves glucose homeostasis in patients with type 2 diabetes. We examined the effects of R-LA on pyruvate metabolism and free fatty acid (FFA) oxidation in primary cultured hepatocytes isolat ...
... Racemic LA (rac-LA) has shown promise in treating diabetic polyneuropathy, and some studies suggest that it improves glucose homeostasis in patients with type 2 diabetes. We examined the effects of R-LA on pyruvate metabolism and free fatty acid (FFA) oxidation in primary cultured hepatocytes isolat ...
How OPTYGEN-HP works
... Some commonalties among these governing bodies include banned substances which fall into one or more of the following categories as listed in Section I A-E of the UCI Prohibited Classes of substance and Prohibited Methods document. A) Stimulants B) Narcotics C) Anabolic agents D) Diuretics and E) Pe ...
... Some commonalties among these governing bodies include banned substances which fall into one or more of the following categories as listed in Section I A-E of the UCI Prohibited Classes of substance and Prohibited Methods document. A) Stimulants B) Narcotics C) Anabolic agents D) Diuretics and E) Pe ...
Quadriceps Strain
... muscles. If normal walking hurts, shorten your stride. Do not play sports until the pain is gone and your doctor has given you permission. Cold—Apply ice or a cold pack to the quadriceps area for 15 to 20 minutes, 4 times a day for several days after the injury. Wrap the ice or cold pack in a towel. ...
... muscles. If normal walking hurts, shorten your stride. Do not play sports until the pain is gone and your doctor has given you permission. Cold—Apply ice or a cold pack to the quadriceps area for 15 to 20 minutes, 4 times a day for several days after the injury. Wrap the ice or cold pack in a towel. ...
Evidence for the presence of calsequestrin in two structurally
... contaminating proteins . After a brief staining with Coomassie Blue, the 55,000dalton band of cardiac calsequestrin was excised and then extracted from the gel with 0.1 % SDS and 10 mM sodium bicarbonate . Antisera were raised in rabbits by a series of intramuscular injections with 0 .5 mg of electr ...
... contaminating proteins . After a brief staining with Coomassie Blue, the 55,000dalton band of cardiac calsequestrin was excised and then extracted from the gel with 0.1 % SDS and 10 mM sodium bicarbonate . Antisera were raised in rabbits by a series of intramuscular injections with 0 .5 mg of electr ...
File
... Regulation of the pathways of cellular respiration by feedback inhibition — regulation of ATP production, by inhibition of phosphofructokinase by ATP and citrate, synchronisation of rates of glycolysis and citric acid cycle. Energy systems in muscle cells. Creatine phosphate breaks down to release e ...
... Regulation of the pathways of cellular respiration by feedback inhibition — regulation of ATP production, by inhibition of phosphofructokinase by ATP and citrate, synchronisation of rates of glycolysis and citric acid cycle. Energy systems in muscle cells. Creatine phosphate breaks down to release e ...
Impaired overload-induced muscle growth is associated with
... East Carolina University Brody School of Medicine. Body weights, muscle weights and AMPK results have been previously reported for these animals (Thomson & Gordon, 2005). The FBN rat was chosen for use in this study because it is considered to be the preferred model for the study of age-related skel ...
... East Carolina University Brody School of Medicine. Body weights, muscle weights and AMPK results have been previously reported for these animals (Thomson & Gordon, 2005). The FBN rat was chosen for use in this study because it is considered to be the preferred model for the study of age-related skel ...