ppt - Sol Genomics Network
... sequence data from European plant sequencing consortia along with publically available data from the international initiative Plants DB communicates bioinformatic analysis data (visualization, genetic elements, structural data, ontologies, domains...; BLAST, browse and search,…comparative analysis ...
... sequence data from European plant sequencing consortia along with publically available data from the international initiative Plants DB communicates bioinformatic analysis data (visualization, genetic elements, structural data, ontologies, domains...; BLAST, browse and search,…comparative analysis ...
Gene Section TRA (T cell Receptor Alpha) Atlas of Genetics and Cytogenetics
... The most 5' TRAV genes occupy the most centromeric position, whereas the TRAC genes, 3' of the locus, is the most telomeric gene in the TRA locus. The organization of the TRAJ segments on a large area is quite unusual and has not been observed in the other immunoglobulin or T cell receptor loci. Mor ...
... The most 5' TRAV genes occupy the most centromeric position, whereas the TRAC genes, 3' of the locus, is the most telomeric gene in the TRA locus. The organization of the TRAJ segments on a large area is quite unusual and has not been observed in the other immunoglobulin or T cell receptor loci. Mor ...
Mutation detection and correction experiments in
... exonucleases; the RNA residues are methylated, which also prevents degradation. Once transported into the nucleus, the RDO is thought to bind to the DNA target on the basis of a homology region 25 base pairs in length. It is postulated that the presence of the RNA residues makes base pairing more ef ...
... exonucleases; the RNA residues are methylated, which also prevents degradation. Once transported into the nucleus, the RDO is thought to bind to the DNA target on the basis of a homology region 25 base pairs in length. It is postulated that the presence of the RNA residues makes base pairing more ef ...
HARVARDx | HARPH525T114-G007300_TCPT
... many analyses. In this figure we see that there are these dendrograms up on top and on the side. We're going to learn what those are and how to make them. And then we also see these colors. And we're going to explain what those are as well. So to understand those dendrograms, we have to explain clus ...
... many analyses. In this figure we see that there are these dendrograms up on top and on the side. We're going to learn what those are and how to make them. And then we also see these colors. And we're going to explain what those are as well. So to understand those dendrograms, we have to explain clus ...
Gene Section CTNNB1 (Catenin, beta-1) Atlas of Genetics and Cytogenetics
... family. b-catenin is assumed to transactivate mostly unknown target genes, which may stimulate cell proliferation (acts as an oncogene) or inhibit apoptosis. The b-catenin level in the cell is regulated by its association with the adenomatous polyposis coli (APC) tumor suppressor protein, axin and G ...
... family. b-catenin is assumed to transactivate mostly unknown target genes, which may stimulate cell proliferation (acts as an oncogene) or inhibit apoptosis. The b-catenin level in the cell is regulated by its association with the adenomatous polyposis coli (APC) tumor suppressor protein, axin and G ...
Health 1020
... different types of non-small cell cancer include squamous cell carcinoma, large cell carcinoma, pleomorphic, carcinoid tumor, salivary gland carcinoma, and adenocarcinoma. Small cell lung cancer only has two main types and does not have as many variations as non-small cell cancer. The two types are ...
... different types of non-small cell cancer include squamous cell carcinoma, large cell carcinoma, pleomorphic, carcinoid tumor, salivary gland carcinoma, and adenocarcinoma. Small cell lung cancer only has two main types and does not have as many variations as non-small cell cancer. The two types are ...
High-moderate or increased risk of Bowel Cancer
... Can tests show if the bowel cancer in my family is due to an inherited tendency? Sometimes it is possible to carry out a test on a sample of cancer tissue or a polyp that was removed at the time of surgery or colonoscopy. This is called an immunohistochemistry test (IHC). It looks for the presence o ...
... Can tests show if the bowel cancer in my family is due to an inherited tendency? Sometimes it is possible to carry out a test on a sample of cancer tissue or a polyp that was removed at the time of surgery or colonoscopy. This is called an immunohistochemistry test (IHC). It looks for the presence o ...
Gene Name
... not be affected by a small number of differentially expressed genes (eg. the Xchromosome genes or other sex-specific genes in our study). The array contains over 15K cDNA sets therefore we can assume overall autosomal gene expression is equal between female and male mouse tissue and ES cells (or emb ...
... not be affected by a small number of differentially expressed genes (eg. the Xchromosome genes or other sex-specific genes in our study). The array contains over 15K cDNA sets therefore we can assume overall autosomal gene expression is equal between female and male mouse tissue and ES cells (or emb ...
Hereditary Hyperferritinemia-Cataract Syndrome: Two Novel
... Kindred I. The 51-year-old male proband of English origin developed visual symptoms in his mid-thirties from cataracts, but was otherwise asymptomatic. Investigations revealed a serum ferritin of 1,389 µg/L but normal transferrin saturation. Similar abnormalities were noted in the proband’s sister, ...
... Kindred I. The 51-year-old male proband of English origin developed visual symptoms in his mid-thirties from cataracts, but was otherwise asymptomatic. Investigations revealed a serum ferritin of 1,389 µg/L but normal transferrin saturation. Similar abnormalities were noted in the proband’s sister, ...
- ResearchOnline@JCU
... Amongst its substrates are Wnt agonist frizzled receptors, which are targeted to the lysosome for degradation;12 a mutation in the RING finger domain that inactivated E3 ligase activity increased Wnt signaling.13 Complete Sanger sequencing of RNF43 in each extant member of the pedigree revealed one a ...
... Amongst its substrates are Wnt agonist frizzled receptors, which are targeted to the lysosome for degradation;12 a mutation in the RING finger domain that inactivated E3 ligase activity increased Wnt signaling.13 Complete Sanger sequencing of RNF43 in each extant member of the pedigree revealed one a ...
Medicago Genomics and Bioinformatics
... Gene Annotation Using GO Terms • Association of GO terms with gene products based on evidence from literature reference or computational analysis. • The creation of GO and the association of GO terms with gene products (gene annotation) are two independent operations. • A gene can be associated wit ...
... Gene Annotation Using GO Terms • Association of GO terms with gene products based on evidence from literature reference or computational analysis. • The creation of GO and the association of GO terms with gene products (gene annotation) are two independent operations. • A gene can be associated wit ...
Case report
... interested in sensopathic toys than age-appropriate games. Socializing with peers has always been a problem. He has always been oversensitive for loud noises. He had problems to adjust to changes. Pediatric assessment of the encopresis did not show any somatic reasons for the problem. He had marked ...
... interested in sensopathic toys than age-appropriate games. Socializing with peers has always been a problem. He has always been oversensitive for loud noises. He had problems to adjust to changes. Pediatric assessment of the encopresis did not show any somatic reasons for the problem. He had marked ...
Developmental genetics of ribosome synthesis
... detectable protein accumulation occurs. This and other observations suggested that at the end of oogenesis the efficiency of translation drops by about 20-fold2t. A similar decrease in the rates of protein synthesis also occurs when Drosophila tissue culture cells are subjected to heat shock2z. The ...
... detectable protein accumulation occurs. This and other observations suggested that at the end of oogenesis the efficiency of translation drops by about 20-fold2t. A similar decrease in the rates of protein synthesis also occurs when Drosophila tissue culture cells are subjected to heat shock2z. The ...
A Statistical Approach to Literature
... – Problem: not weight term count (as long as there is one co-occurrence between a term and a gene, then they are associated) ...
... – Problem: not weight term count (as long as there is one co-occurrence between a term and a gene, then they are associated) ...
Controlling the Ir Genes - The Journal of Immunology
... during the development of B lymphocytes and could be induced in many cell types by IFN-␥ (4). At this time, few mammalian gene or cell type-specific transcription factors were known, and the mechanism(s) by which they functioned to recruit RNA polymerases was based mostly on in vitro system models a ...
... during the development of B lymphocytes and could be induced in many cell types by IFN-␥ (4). At this time, few mammalian gene or cell type-specific transcription factors were known, and the mechanism(s) by which they functioned to recruit RNA polymerases was based mostly on in vitro system models a ...
Clinical Cancer Genetics - Scioto County Medical Society
... Understand an individual’s risk of developing cancer Understand the options for dealing with an increased risk for cancer Choose a course of action for managing cancer risk that seems personally appropriate (genetic testing, screening or ...
... Understand an individual’s risk of developing cancer Understand the options for dealing with an increased risk for cancer Choose a course of action for managing cancer risk that seems personally appropriate (genetic testing, screening or ...
lec9
... significantly different across conditions) conditions), and test if a GO term is over-represented in the subset • Another angle to consider the problem is to start with predefined gene sets instead of data-determined short list. ...
... significantly different across conditions) conditions), and test if a GO term is over-represented in the subset • Another angle to consider the problem is to start with predefined gene sets instead of data-determined short list. ...
Gene Section MRE11A (MRE11 meiotic recombination 11 homolog A (S. cerevisiae))
... Jaspers NG, Raams A, Byrd PJ, Petrini JH, Taylor AM. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell. 1999 Dec 10;99(6):577-87 ...
... Jaspers NG, Raams A, Byrd PJ, Petrini JH, Taylor AM. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell. 1999 Dec 10;99(6):577-87 ...
this document - Institute for Agriculture and Trade Policy
... strange genes in the GM construct, is entirely different. It now functions promiscuously across the living world, including animal and human cells [10]. Its destabilising effect on GM crops is such that many scientists, including those who pioneered its use, are now phasing it out. But CaMV 35S prom ...
... strange genes in the GM construct, is entirely different. It now functions promiscuously across the living world, including animal and human cells [10]. Its destabilising effect on GM crops is such that many scientists, including those who pioneered its use, are now phasing it out. But CaMV 35S prom ...
CSIRO_The Hungry Microbiome Project_Colon
... because of HDAC, the enzyme, which appear to be more active in colon cancer cells. [Image changes to show a person’s hand drawing on the diagram and text appears: HDAC is more active in colon cancer cells] So here HDAC is removing all the acetyl groups on histones, resulting in more methylated histo ...
... because of HDAC, the enzyme, which appear to be more active in colon cancer cells. [Image changes to show a person’s hand drawing on the diagram and text appears: HDAC is more active in colon cancer cells] So here HDAC is removing all the acetyl groups on histones, resulting in more methylated histo ...
Oncogenomics
Oncogenomics is a relatively new sub-field of genomics that applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with ""cancer genomics"". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell proliferation and neoplasm formation. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. The success of targeted cancer therapies such as Gleevec, Herceptin, and Avastin raised the hope for oncogenomics to elucidate new targets for cancer treatment.Besides understanding the underlying genetic mechanisms that initiates or drives cancer progression, one of the main goals of oncogenomics is to allow for the development of personalized cancer treatment. Cancer develops due to an accumulation of mutations in DNA. These mutations accumulate randomly, and thus, different DNA mutations and mutation combinations exist between different individuals with the same type of cancer. Thus, identifying and targeting specific mutations which have occurred in an individual patient may lead to increased efficacy of cancer therapy.The completion of the Human Genome Project has greatly facilitated the field of oncogenomics and has increased the abilities of researchers to find cancer causing genes. In addition, the sequencing technologies now available for sequence generation and data analysis have been applied to the study of oncogenomics. With the amount of research conducted on cancer genomes and the accumulation of databases documenting the mutational changes, it has been predicted that the most important cancer-causing mutations, rearrangements, and altered expression levels will be cataloged and well characterized within the next decade.Cancer research may look either on the genomic level at DNA mutations, the epigenetic level at methylation or histone modification changes, the transcription level at altered levels of gene expression, or the protein level at altered levels of protein abundance and function in cancer cells. Oncogenomics focuses on the genomic, epigenomic, and transcript level alterations in cancer.