• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Genome-wide analysis of DNA copy-number
Genome-wide analysis of DNA copy-number

Bio-markers of response
Bio-markers of response

OCR A Level Biology A Level Learner Resource 1
OCR A Level Biology A Level Learner Resource 1

... gene product of the lac Z gene in metabolizing lactose in a bacterium. Relate your answer to respiration. ...
題目: Regulatory mechanism of floral coloration in Oncidium cultivars
題目: Regulatory mechanism of floral coloration in Oncidium cultivars

The Role of Mismatch Repair in Bacterial Evolution
The Role of Mismatch Repair in Bacterial Evolution

... stressful environments and the ability for genetic adaptation by affected bacteria is essential for their evolutionary success. The probability of generation of strains to adapt better to a new environment depends on bacteria’s capacity to produce genomic diversity. Biological evolution results from ...
Nitric Oxide
Nitric Oxide

... ultimately contribute to Oxidative and Nitrosative Stress induced cell death and Apoptosis • Further Detailed Studies needed to have a deeper Insight into Signal transduction pathways involved in Alzheimer Disease ...
ProdoNet: identification and visualization of prokaryotic gene
ProdoNet: identification and visualization of prokaryotic gene

Gene duplication
Gene duplication

7.03 Fall 2003 Problem Set #3 Solutions
7.03 Fall 2003 Problem Set #3 Solutions

... (b) Since none of the 100 Kanr tranductants were Lac+, we can conclude that Tn5 was never co-transduced with lac2+. This indicates that the distance between lac2- and Tn5 is at least one phage head (105 bp). We know from part (a) that Tn5 and lac1- are within one phage head since their cotransductio ...
DNA Technology and Genomics  I.
DNA Technology and Genomics I.

... Genomics, the study of genomes and their interactions, is yielding new insights into fundamental questions about genome organization, the regulation of gene expression, growth and development, and evolution. A. Starting with a long DNA sequence, how does a researcher recognize genes and determine th ...
DNA - Gene - Website Staff UI
DNA - Gene - Website Staff UI

... Is the heritable changes in the genetic material. The term mutation refers to (1) change in the genetic material, (2) the process by which the change occurs. Mutation provides the raw material for evolution. Without mutation, all of genes would exist in only one form and alleles would not exis. Orga ...
Identification of Copy Number Variants using genome graphs.
Identification of Copy Number Variants using genome graphs.

Salmonella Typhi
Salmonella Typhi

Journal of Biotechnology
Journal of Biotechnology

... Gene per gene comparison in two genomes of B. amyloliquefaciens was performed using BLASTp algorithm implementation in the blastall.exe NCBI executable file (Madden, 2002). It was assumed that the genes in two B. amyloliquefaciens genomes showing the best alignment score and e-value below 0.0001 were ...
10/16 - link
10/16 - link

... Comparative genomics also has been used to identify recently mobilized transposons in genetically diverse humans. For example, over 600 recent transposon insertions were identified by examining DNA resequencing traces from 36 genetically diverse humans. ...
Microbial Genetics Thesaurus
Microbial Genetics Thesaurus

GLIS3%20paper%20Dimitri%20JCEM%20Final.
GLIS3%20paper%20Dimitri%20JCEM%20Final.

Introduction Exercise 1: Measuring gene expression
Introduction Exercise 1: Measuring gene expression

... Can you find on the gene cards page an association with MCF-7 cells? Hint: what was MCF-7 for type of cell line again? Each line in the file represents one gene; the 2nd column represents the gene symbol. The Pvalue is a probability that represents the chance to find the expression values that belon ...
Potential Transcriptional Biomarkers in Human Transplant Renal
Potential Transcriptional Biomarkers in Human Transplant Renal

... Introduction: The outcome of human kidney transplantation is significantly different between living donor (LD) and cadaveric donor (CAD). Transcriptomic signatures and signaling pathways in transplant renal biopsies may facilitate disclosing underlying mechanisms and define potential biomarkers that ...
FEBS Lett. 586, 2043-2048 - iSSB
FEBS Lett. 586, 2043-2048 - iSSB

... 3. Replication-associated dosage of genes involved in translation and transcription Replication-associated gene dosage is an important determinant of chromosome organization and dynamics, especially among fast-growing bacteria. The bidirectional replication of bacterial chromosomes leads to transien ...
Interpretation of Arabidopsis Thaliana and T
Interpretation of Arabidopsis Thaliana and T

... • Less cellular process • Less transport process • Less stress response • Less transcription ...
chapter_16
chapter_16

... Variation in chromosome number: Organism with one complete set of chromosomes is said to be euploid (applies to haploid and diploid organisms). Aneuploidy = variation in the number of individual chromosomes (but not the total number of sets of chromosomes). Nondisjunction during meiosis I or II (Ch ...
Epigenetics
Epigenetics

Potential relationship between genotype and clinical
Potential relationship between genotype and clinical

... 37 Spanish PA patients in relation to the mutations found in both PCCA and PCCB genes. We have detected 27 early-onset and 10 late-onset cases, showing remarkably similar biochemical features without relation to either the age of onset of the disease or the defective gene they have. Twenty-one of th ...
Supplemental Table 11
Supplemental Table 11

< 1 ... 161 162 163 164 165 166 167 168 169 ... 504 >

Oncogenomics



Oncogenomics is a relatively new sub-field of genomics that applies high throughput technologies to characterize genes associated with cancer. Oncogenomics is synonymous with ""cancer genomics"". Cancer is a genetic disease caused by accumulation of mutations to DNA leading to unrestrained cell proliferation and neoplasm formation. The goal of oncogenomics is to identify new oncogenes or tumor suppressor genes that may provide new insights into cancer diagnosis, predicting clinical outcome of cancers, and new targets for cancer therapies. The success of targeted cancer therapies such as Gleevec, Herceptin, and Avastin raised the hope for oncogenomics to elucidate new targets for cancer treatment.Besides understanding the underlying genetic mechanisms that initiates or drives cancer progression, one of the main goals of oncogenomics is to allow for the development of personalized cancer treatment. Cancer develops due to an accumulation of mutations in DNA. These mutations accumulate randomly, and thus, different DNA mutations and mutation combinations exist between different individuals with the same type of cancer. Thus, identifying and targeting specific mutations which have occurred in an individual patient may lead to increased efficacy of cancer therapy.The completion of the Human Genome Project has greatly facilitated the field of oncogenomics and has increased the abilities of researchers to find cancer causing genes. In addition, the sequencing technologies now available for sequence generation and data analysis have been applied to the study of oncogenomics. With the amount of research conducted on cancer genomes and the accumulation of databases documenting the mutational changes, it has been predicted that the most important cancer-causing mutations, rearrangements, and altered expression levels will be cataloged and well characterized within the next decade.Cancer research may look either on the genomic level at DNA mutations, the epigenetic level at methylation or histone modification changes, the transcription level at altered levels of gene expression, or the protein level at altered levels of protein abundance and function in cancer cells. Oncogenomics focuses on the genomic, epigenomic, and transcript level alterations in cancer.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report