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KARNATAKA COMMON ENTRANCE TEST – MAY, 2016 BIOLOGY
KARNATAKA COMMON ENTRANCE TEST – MAY, 2016 BIOLOGY

1: Summary and Options
1: Summary and Options

A-10484A SNPs. Mutations and DNA Sequence
A-10484A SNPs. Mutations and DNA Sequence

... We carried out single-plex and multiplex SNP reactions using a panel of 10 SNPs. PCR products were obtained for each individual SNP as separate reactions. Primers were designed so that none of the products exceeded 1000 bps in size. During design they were also masked for repeats using the human rep ...
CHARACTERlZATION OF THE ~ 0 CHONDRIA . L DNA MOLECULE
CHARACTERlZATION OF THE ~ 0 CHONDRIA . L DNA MOLECULE

... genomes are compared between insects, sea urchins and nematodes (Clary and Wolstenholme, 1985; Crozier and Crozier, 1993; Jacobs et al., 1988; Cantatore et al., 1989; Okiomoto et al., 1992). Furthemore, among insects, the location and orientation of pmtein and rRNA genes and the putative control reg ...
Foundations in Microbiology
Foundations in Microbiology

... Action of restriction endonucleases. (1) A restriction endonuclease recognizes and cleaves DNA at the site of a specific palindromic sequence. Cleavage usually produces staggered tails called sticky ends that accept complementary tails for gene splicing. This palindrome is cut by Aci I. (2) The stic ...
The msh2 Gene of Schizosaccharomyces pombe Is
The msh2 Gene of Schizosaccharomyces pombe Is

... We have identified in the fission yeast Schizosaccharomyces pombe a MutS homolog that shows highest homology to the Msh2 subgroup. msh2 disruption gives rise to increased mitotic mutation rates and increased levels of postmeiotic segregation of genetic markers. In bandshift assays performed with msh ...
RHD - Labex
RHD - Labex

...  The importance of the Rh factor was the better blood finger print for criminal matters  M, N, or P factors where known and Rh factor was just an additional one  Later it was recognized that the new Rh factor was associated with problem in transfusions  Between 1940 to 1946 Philip Levine discove ...
Unusual chromosome structure of fission yeast DNA in mouse cells
Unusual chromosome structure of fission yeast DNA in mouse cells

... mosome) is developmentally regulated and appears to take part in inactivating large parts of the genome. Therefore, different DNA sequences and their epigenetic modifications have various cytological expressions in mammalian cells. DNA at primary constrictions and constitutive heterochromatin is com ...
the association of chloroplast dna with photosynthetic membrane
the association of chloroplast dna with photosynthetic membrane

... in the electron microscope they appear as in Figs. 6-8. They are bound by a membrane to which adhere varying numbers of grana lamellae. The number of grana lamellae seen in a single section will vary according to the section plane. The grana are partially disrupted due to the isolation in the 3-5 mM ...
Evolutionary Origin of Recombination during Meiosis
Evolutionary Origin of Recombination during Meiosis

... bacterial cell, whereby nonsister homologous chromosomes (or parts of chromosomes) originating from different parent cells align and undergo genetic recombination. The recombined DNA is passed on to a progeny bacterium. The core genes for meiosis were very likely present in the common ancestor of al ...
Neanderthal-human Hybrids
Neanderthal-human Hybrids

... Figure 1 | Possible outcomes of Neanderthal-Human Interbreeding. Mammals contain two different types of DNA: (i) nuclear DNA, which is from both parents and contributes directly to the phenotype, and (ii) mitochondrial DNA, which is involved in energy regulation and is exclusively maternally inherit ...
8.7 Mutations - Cloudfront.net
8.7 Mutations - Cloudfront.net

Intelligent Icons: Integrating Lite-Weight Data Mining
Intelligent Icons: Integrating Lite-Weight Data Mining

... The three files in the example are ASCII text files, each of which contains approximately 16,000 base pairs of mitochondrial DNA. Here we used string edit distance as suggested in [15] to measure the distance between file names, and Euclidean distance to measure the distance between the file icons ( ...
Functional analysis of plastid DNA replication origins in tobacco by
Functional analysis of plastid DNA replication origins in tobacco by

... were obtained with each of these plasmids after bombardment of tobacco leaves. Plastome insertion of the aadA sequence at the targeted position was verified by PCR (data not shown). Transplastomic lines were subjected to repeated cycles of vegetative regeneration before Southern analysis. AK1 transf ...
Prediction and investigation of novel proteins in DNA double
Prediction and investigation of novel proteins in DNA double

... causing fragmentation of the DNA strands. Mis-repaired and unrepaired DSBs lead to chromosomal rearrangement and genomic instability promoting tumorigenesis or cell death. DSBs are primarily repaired by two independent and highly conserved pathways: homologous recombination (HR) and non-homologous e ...
Chapter 11 - Nucleic Acid Structure and DNA Replication
Chapter 11 - Nucleic Acid Structure and DNA Replication

... namely, proteins and DNA. Scientists of this era viewed proteins as being more biochemically complex because they are made from 20 different amino acids. Furthermore, biochemists already knew that proteins perform an amazingly wide range of functions. Complexity seemed an important prerequisite for ...
Molecular events during translocation and proofreading extracted
Molecular events during translocation and proofreading extracted

... are difficult, if not impossible, to capture by static crystallography. These conformations are often key to mechanistic understanding and could be explored by a back calculation based on molecular distance geometry (12), the chief computational algorithm in nucleic magnetic resonance spectroscopy. ...
The rapidly evolving field of plant centromeres
The rapidly evolving field of plant centromeres

... they are clustered within and around centromeres. On the basis of this work, Wright et al. [33] suggested that the apparent centromeric abundance of transposons is not due to suppressed recombination but rather results from ample non-coding DNA targets; insertions into chromosome arms, by contrast, ...
DNA MUTATION, REPAIR, AND TRANSPOSITION
DNA MUTATION, REPAIR, AND TRANSPOSITION

... Therefore, DNA molecule I is the least sensitive, while molecule III is the most sensitive. 24. Frameshift mutations are caused by insertions or deletions of bases (that are not multiples of 3). These will shift the reading frame for all codons downstream from the mutation. Single base-substitutions ...
Deconstructing the Genome: DNA at High Resolution
Deconstructing the Genome: DNA at High Resolution

... which growth on a restricting host modifies a virus so that succeeding generations grow more efficiently on that same host is known as modification. What mechanisms account for restriction and modification? Studies following viral DNA after bacterial infection found that during restriction, the vira ...
Comparison of the separation of Candida albicans chromosome
Comparison of the separation of Candida albicans chromosome

... composed of both bands F and G, and band E/H of Figure 3 was a doublet composed of both bands E and H. To test if bands F/G and E/H of Figure 3 were doublets, we attempted to separate by FIGE the chromosome components in the doublets by increasing the switching interval from 100 seconds forward and ...
p53-associated 3 exonuclease activity in nuclear and cytoplasmic
p53-associated 3 exonuclease activity in nuclear and cytoplasmic

... the maintenance of genomic stability. Notably, the exonuclease activity of p53 must not be restricted to its noninduced state, but might also be exerted by a subclass of p53 after DNA damage when the protein is able to display its full range of possible biochemical activities (Albrechtsen et al., 19 ...
20Sexual Reproduction, Meiosis, and Genetic Recombination
20Sexual Reproduction, Meiosis, and Genetic Recombination

... mutations, which are unpredictable alterations in DNA base sequence. Mutations are rare events, and beneficial mutations are even rarer. But when beneficial mutations do arise, it is clearly advantageous to preserve them in the population. It can be even more beneficial to bring mutations together i ...
Geminivirus Replication Origins Have a Modular
Geminivirus Replication Origins Have a Modular

... TGMV A (Figure 1, cf. lanes 2 and 3), while BGMV B only replicated in the presence of BGMV A (cf. lanes 6 and 7). These results established that BGMV is able to replicate efficiently in tobacco cells and that, similar to TGMV A (Rogers et al., 1986; Hayes and Buck, 1989), BGMV A provides all of the ...
Mitochondria in lung biology and pathology: more than - AJP-Lung
Mitochondria in lung biology and pathology: more than - AJP-Lung

... nuclear DNA, in which the state of compaction, its interactions with multiple transcription factors and coactivators, and epigenetic determinants are all exquisitely regulated processes culminating in precise control of gene expression, the mitochondrial genome is expressed as a single unit and its ...
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DNA damage theory of aging

The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).In humans and other mammals, DNA damage occurs frequently and DNA repair processes have evolved to compensate. In estimates made for mice, on average approximately 1,500 to 7,000 DNA lesions occur per hour in each mouse cell, or about 36,000 to 160,000 per cell per day. In any cell some DNA damage may remain despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, such as cells in the brain, skeletal and cardiac muscle.
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