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IJBCP International Journal of Basic & Clinical
IJBCP International Journal of Basic & Clinical

... safe and efficacious, and it also got German approval for the same. It was found that the anti-inflammatory actions of DMF contributed to its efficacy in psoriasis. This anti-inflammatory action of DMF created interest using DMF in other auto-immune or inflammatory diseases, including MS. DMF acts b ...
A Reference for Health Care Professionals
A Reference for Health Care Professionals

... those with idiopathic autoimmune MG.10-16 The diagnosis can be easily missed, especially in patients presenting with respiratory failure.17 Myasthenia is reported to occur in from 1% to 7% of all patients on penicillamine.18,19 One group found MG in 5 out of 71 consecutive patients with penicillamin ...
Full PDF - IOSR Journal of Pharmacy
Full PDF - IOSR Journal of Pharmacy

... Parkinson‟s disease (PD) is a slowly progressive neurodegenerative disease caused when a small group of brain cells that control body movements die. This disease was first described by James Parkinson in 1817. It is characterised clinically by bradykinesia, resulting tremor, rigidity and postural in ...
data sheet
data sheet

... Co-morbidity of psychiatric disorders in ADHD is common and should be taken into account when prescribing stimulant products. In the case of emergent psychiatric symptoms or exacerbation of preexisting psychiatric disorders, methylphenidate should not be given unless the benefits outweigh the risks ...
Medicinal Properties of Strobilanthes crispus: A Review
Medicinal Properties of Strobilanthes crispus: A Review

... teratoma and Hodgkin’s disease [5]. Natural products have recently regained its prominent role in drug discovery with the increasing recognition of significance of their structural diversity and expanding exploration of their therapeutic use. One of the plants that have elicited a great deal of inte ...
322 PHT Tablet
322 PHT Tablet

...  SLS improves permeation of drug through biological membrane since it destroys the path through which drug has to pass and thus minimizing the path length for the drug to travel. Wetting agents are mainly added when hydrophobic drug is to be formulated into tablet. SLS, Sodium diisobutyl sulfosuc ...
dose - Recherche Clinique Paris Centre
dose - Recherche Clinique Paris Centre

... ● Part of the Registration Dossier for CNS acting drugs (primary or secondary effects) • Based on behavioral effects in animals • Dependence, overdose, and drug abuse liability potential ...
PRODUCT MONOGRAPH Frisium® (clobazam) Tablets, 10 MG
PRODUCT MONOGRAPH Frisium® (clobazam) Tablets, 10 MG

... FRISIUM(clobazam) is a 1,5-benzodiazepine with anticonvulsant properties. In general, the mode of antiepileptic action of clobazam is probably largely analogous to that of the 1,4-benzodiazepines. The differences between clobazam (a 1,5-benzodiazepine) and the 1,4-benzodiazepines in terms of therape ...
Amphetamine and Related Drugs
Amphetamine and Related Drugs

... in the treatment of the sleeping disorder, narcolepsy, and the behavioral syndrome called minimal brain dysfunction, which today is called attention deficit hyperactivity disorder (ADHD). During World War II, amphetamine was widely used to keep the fighting men going and both dextroamphetamine (Dexe ...
Glaucoma Management and Ocular Surface Disease Disclosure
Glaucoma Management and Ocular Surface Disease Disclosure

... 1. Fechtner, R, Budenz, D, Godfrey D. Prevalence of ocular surface disease symptoms in glaucoma patients on IOP-lowering medications. Presented at: Annual Meeting of the American Glaucoma Society ; March 2008; Washington DC. 2. Leung E, et al. Prevalence of Ocular Surface Disease in Glaucoma Patient ...
What is the first choice antidepressant for patients with renal
What is the first choice antidepressant for patients with renal

... Both The Psychotropic Drug Directory and The Maudsley Prescribing Guidelines provide information on individual drugs where available [5,6]. The Psychotropic Drug Directory considers sertraline a higher risk antidepressant, compared with the recommendation in The Maudsley Guidelines. This view is bas ...
Opioid Complications and Side Effects
Opioid Complications and Side Effects

... ance, on the other hand, results in a decrease in efficacy as compensatory mechanisms are incorporated or learned. For instance, a patient in a setting where he or she usually consumes the drug typically expects the drug to be less effective; however, if the same person takes the same amount of drug ...
A prospective clinical study of theophylline safety in 3810
A prospective clinical study of theophylline safety in 3810

... (COPD) who had been treated with sustained-release theophylline tablets (THEODURs) at a dose of 400 mg/day for 1–6 months, in principle. Among 3798 protocol-complying patients (mean age: 73.870.10 years, 1997 with COPD), 261 theophylline-related adverse events were observed in 179 (4.71%) patients. ...
What`s in the Pipeline: New HIV Drugs
What`s in the Pipeline: New HIV Drugs

... Health (NIH) as well as at the Centers for Disease Control and Prevention (CDC). If NIH and CDC do not soon begin to receive budget increases, the long-term prospect for biomedical research—including the basic science research that yields breakthroughs against diseases such as HIV, HCV, and TB—will ...
Anti-Nicotine Vaccine: An Insight
Anti-Nicotine Vaccine: An Insight

... 16. Sliwinska-Mosson M, Zielen I, Milnerowicz H. New trends in the treatment of nicotine addiction. Acta Pol Pharm 2014;71:525-30. 17. Jennings GT, Bachmann MF. The coming of age of virus-like ...
drug delivery
drug delivery

... • The AngioSculptX catheter is intended to treat a single lesion in a single patient; do not re-use the AngioSculptX catheter to dilate additional lesions. • Prior to angioplasty, examine the catheter to verify functionality, catheter integrity and to ensure that its size and length are suitable f ...
Resistant Hypertension: Newer Management Approaches
Resistant Hypertension: Newer Management Approaches

Formulation Considerations of Inhaled Products
Formulation Considerations of Inhaled Products

... Formulation Considerations of Inhaled Products Inhalation Therapy Nebulizers and Formulations Dry Powder Inhalers and Formulations Metered Dose Inhalers (MDI) and Formulations Conclusions ...
Fixed combination of arthemether and lumefantrine
Fixed combination of arthemether and lumefantrine

... rapid clinical and parasitological cure; (ii). there is as yet no documented parasite resistance to them; (iii). they reduce gametocyte carrier rates; and (iv). are generally well tolerated (1998, 2001a). There is however limited clinical experience for many of the combinations being considered. It ...
WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTE 31ST EXPERT COMMITTEE
WORLD HEALTH ORGANIZATION ORGANISATION MONDIALE DE LA SANTE 31ST EXPERT COMMITTEE

... Outline of the review procedure Since 1990, WHO’s review of psychoactive substances has been carried out in two steps, in accordance with the Revised Guidelines for the WHO Review of DependenceProducing Psychoactive Substances for International Control adopted by the Executive Board that same year. ...
The Potential of Cyclodextrins as Novel Active Pharmaceutical
The Potential of Cyclodextrins as Novel Active Pharmaceutical

... The deviation from linearity can be positive (AP ) or negative (AN ) (Figure 3). A positive or negative deviation form linearity implies that the molar ratio between ligand and substrate (CD and drug respectively) is not 1:1 [10]. In this case, it is very difficult to predict from these diagrams the ...
Are placebos inert or powerful? Vice versa
Are placebos inert or powerful? Vice versa

... distributional effects. To study a treatment, patients are selected at one end of a distribution, for example blood pressure, cholesterol and depression. These commodities vary with time. When one looks at the distribution later, the distribution may look the same, but the positions of individuals w ...
Deep Dive into the PIM and DDI Data
Deep Dive into the PIM and DDI Data

... table Brand_Name / out=Brand_Name_freq; run; Figure 2 shows the top 10 PIM in Minnesota for the first two quarters of 2010. Most of these are the generic names as they show up as prescribed most often. For the drug class other, nitrofurantoin monohydrate/macrocrystals (Macrobid) is number one on the ...
TDS Chitosan VacciGrade™ : 100 mg (vac-cht)
TDS Chitosan VacciGrade™ : 100 mg (vac-cht)

... Chitosan is the deacetylated derivative of chitin, a polysaccharide found in the exoskeletons of crustaceans and in the cell walls of fungi. Chitosan is well known for its use in drug delivery, where it is used as a bioadhesive agent and to enhance the absorption of proteins across mucosal surfaces. ...
B.Pharmacy Syllabus 2015
B.Pharmacy Syllabus 2015

... forms of descriptive and argumentative essays Learning and Teaching Activities: PART A (Reading) The prescribed reading textbook for students will be S. P. Dhanavel English and Communication Skills for Students of Science and Engineering (with audio CD), Orient Blackswan. They will go through the re ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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