Personalized Medicine - Quo Vadis
... Johnson & Johnson has proposed that Britain’s national health service pay for the cancer drug Velcade, but only for people who benefit from the medicine, which can cost $48,000 a patient. The company would refund any money spent on patients whose tumors do not shrink sufficiently after a trial treat ...
... Johnson & Johnson has proposed that Britain’s national health service pay for the cancer drug Velcade, but only for people who benefit from the medicine, which can cost $48,000 a patient. The company would refund any money spent on patients whose tumors do not shrink sufficiently after a trial treat ...
Legal and Illegal Drugs - Haverford School District
... Alcohol is not always thought of as being a drug, but it is. A drug is a chemical substance that is taken to cause changes in a person’s body or behaviors. Alcohol is a powerful depressant. A depressant is: a drug that slows the brain and body reactions. It can cause confusion, decreased alertness, ...
... Alcohol is not always thought of as being a drug, but it is. A drug is a chemical substance that is taken to cause changes in a person’s body or behaviors. Alcohol is a powerful depressant. A depressant is: a drug that slows the brain and body reactions. It can cause confusion, decreased alertness, ...
Slide 1
... to specific cannabinoid receptors in brain (CB-1) and PNS (CB-2). THC mimics action of endogenous cannabinoid (anandamide) ◦ exist in brain in quantities that exceed more NT ...
... to specific cannabinoid receptors in brain (CB-1) and PNS (CB-2). THC mimics action of endogenous cannabinoid (anandamide) ◦ exist in brain in quantities that exceed more NT ...
Drugs that may Cause or Worsen Symptoms of Myasthenia Gravis
... Associated with more common or more severe adverse events Associated with less common or less severe adverse events *Indicates agents with documented effects in MG, other drugs belonging to the same drug classes (benzodiazepines, beta-blockers, muscle relaxants) may have similar effects and should b ...
... Associated with more common or more severe adverse events Associated with less common or less severe adverse events *Indicates agents with documented effects in MG, other drugs belonging to the same drug classes (benzodiazepines, beta-blockers, muscle relaxants) may have similar effects and should b ...
indiv_drugs_f14
... • Potential anxiety/panic • Experiences can vary widely • Serotonin receptors may be excited or inhibited • LSD experimentation on British soldiers (YouTube.com) • Overdose thought to be rare, but some individuals may not respond well, or may experience problems if drug is different than LSD ...
... • Potential anxiety/panic • Experiences can vary widely • Serotonin receptors may be excited or inhibited • LSD experimentation on British soldiers (YouTube.com) • Overdose thought to be rare, but some individuals may not respond well, or may experience problems if drug is different than LSD ...
Treatment and Therapies
... • Different parts of the brain control different psychological processes • For example= Frontal lobe • Limbic system? • Abnormalities in the brain can cause psychological symptoms: Parkinson‘s • Disconnection or destruction of those brain tissues can alleviate /cure the problem • Psychosurgery has s ...
... • Different parts of the brain control different psychological processes • For example= Frontal lobe • Limbic system? • Abnormalities in the brain can cause psychological symptoms: Parkinson‘s • Disconnection or destruction of those brain tissues can alleviate /cure the problem • Psychosurgery has s ...
A Brief Overview of Drugs of Abuse (pages 1-17) Read Pages 1
... The Addictive Process: The addictive process involves use, misuse, abuse and dependence. Regardless of the chemical, the process is the same. After use of a psychoactive chemical, the central nervous system is affected and causes physiological and mental changes to take place. It is the mental chang ...
... The Addictive Process: The addictive process involves use, misuse, abuse and dependence. Regardless of the chemical, the process is the same. After use of a psychoactive chemical, the central nervous system is affected and causes physiological and mental changes to take place. It is the mental chang ...
Muscle Relaxants
... 2. Benztropine (Cogentin)- used in elderly who can’t tolerate artane 3. Trihexyphenidyl (Artane) – most frequenty used G. Dopaminergic drugs are also used to treat parkinsons (not anticholinergics, just putting this here b/c it relates to treatment of parkinsonism) 1. Action: increase levels of DA i ...
... 2. Benztropine (Cogentin)- used in elderly who can’t tolerate artane 3. Trihexyphenidyl (Artane) – most frequenty used G. Dopaminergic drugs are also used to treat parkinsons (not anticholinergics, just putting this here b/c it relates to treatment of parkinsonism) 1. Action: increase levels of DA i ...
Pharmacology MCQs: 07/05/02
... 3. Regarding amide local anaesthetics (LA) a. Lignocaine is metabolised in the liver faster than any of the other amide local anaesthetics b. Allergies to amide local anaesthetics are more common than with the ester Las c. Prilocaine is the most cardiotoxic amide LA d. Cocaine is an amide LA which i ...
... 3. Regarding amide local anaesthetics (LA) a. Lignocaine is metabolised in the liver faster than any of the other amide local anaesthetics b. Allergies to amide local anaesthetics are more common than with the ester Las c. Prilocaine is the most cardiotoxic amide LA d. Cocaine is an amide LA which i ...
7-Sedative Hypnotic
... depression of CNS (may be fatal) 2- Induction of P450 thus the rate at which they are metabolized increases over the first few days of administration. Also, it leads to increased metabolism of other drugs e.g. estrogen and warfarin ( oral contraceptives and ...
... depression of CNS (may be fatal) 2- Induction of P450 thus the rate at which they are metabolized increases over the first few days of administration. Also, it leads to increased metabolism of other drugs e.g. estrogen and warfarin ( oral contraceptives and ...
Drug Intoxication and Withdrawal - CA
... Tx of Stimulant WD and Dependence • No proven tx, but a number of research avenues • Modafinil: mild stimulant, ↑ glutamate; blocks euphoria – May attenuate cocaine w/d – Not effective for methamphetamine dependence ...
... Tx of Stimulant WD and Dependence • No proven tx, but a number of research avenues • Modafinil: mild stimulant, ↑ glutamate; blocks euphoria – May attenuate cocaine w/d – Not effective for methamphetamine dependence ...
10 Similarities of Sugar, Junk Food and Drugs
... Cravings for junk foods are actually very similar to cravings for drugs, cigarettes and other addictive substances. The obsessive nature and thought processes are identical. 3. Imaging Studies Have Shown That Junk Foods Light up the Same Brain Areas as Drugs of Abuse Tracking activity in the brain ...
... Cravings for junk foods are actually very similar to cravings for drugs, cigarettes and other addictive substances. The obsessive nature and thought processes are identical. 3. Imaging Studies Have Shown That Junk Foods Light up the Same Brain Areas as Drugs of Abuse Tracking activity in the brain ...
Slide 1
... • Dopamine is heavily involved in motor functions. – Long term treatment with antipsychotics (dopamine blockers) can cause movement (a.k.a extrapyramidal) side effects • Tardive dyskinesia occurs in about one third of patients ...
... • Dopamine is heavily involved in motor functions. – Long term treatment with antipsychotics (dopamine blockers) can cause movement (a.k.a extrapyramidal) side effects • Tardive dyskinesia occurs in about one third of patients ...
DRUG INTERACTIONS
... the cytochrome P450 (CYP) system that are responsible for many of the phase 1 biotransformations of drugs. These metabolic transformations, such as oxidation, reduction and hydrolysis, produce a molecule that is suitable for conjugation. Those of importance in the metabolism of psychotropic drugs ar ...
... the cytochrome P450 (CYP) system that are responsible for many of the phase 1 biotransformations of drugs. These metabolic transformations, such as oxidation, reduction and hydrolysis, produce a molecule that is suitable for conjugation. Those of importance in the metabolism of psychotropic drugs ar ...
Psychotropic Meds - nursing-
... Or try: http://www.wisconline.com/objects/index_tj.asp?objID=NUR3503 ...
... Or try: http://www.wisconline.com/objects/index_tj.asp?objID=NUR3503 ...
PGC-1a: a master gene that is hard to master
... revealed decreased levels of PGC-1a and its mitochondrial target genes [5]. This points to a role for PGC-1a in disease pathogenesis, suggesting that it could be a promising target for early intervention in PD. In cells, the levels of PGC-1a are tightly regulated and influenced by both environmental ...
... revealed decreased levels of PGC-1a and its mitochondrial target genes [5]. This points to a role for PGC-1a in disease pathogenesis, suggesting that it could be a promising target for early intervention in PD. In cells, the levels of PGC-1a are tightly regulated and influenced by both environmental ...
q-dips: computer-based prediction of known and potential drug
... University Hospital, Geneva, Switzerland ...
... University Hospital, Geneva, Switzerland ...
UNIT 6 – DRUGS AND ALCOHOL
... Dilate – to get bigger, or more open (dilation) Dope - informal cannabis, or, more generally, any type of illegal drug Euphoric high - extremely happy and excited and not thinking or behaving normally because of taking drugs Fine - an amount of money that has to be paid as a punishment for not obeyi ...
... Dilate – to get bigger, or more open (dilation) Dope - informal cannabis, or, more generally, any type of illegal drug Euphoric high - extremely happy and excited and not thinking or behaving normally because of taking drugs Fine - an amount of money that has to be paid as a punishment for not obeyi ...
Receptor Antagonists Competitive Antagonist • drug acts at the
... In a tissue, where there is no spare receptors, a partial agonist cannot cause a maximal response even if it is bound to all receptors. If an agonist is a partial agonist, but the tissue has lots of reserve (spare) receptors, a partial agonist may appear to be a full agonist because it can cause a m ...
... In a tissue, where there is no spare receptors, a partial agonist cannot cause a maximal response even if it is bound to all receptors. If an agonist is a partial agonist, but the tissue has lots of reserve (spare) receptors, a partial agonist may appear to be a full agonist because it can cause a m ...
CNS Acting Drugs
... Alzheimer’s disease: is a brain disorder in elderly due to acetylcholine deficiency. It is characterized by pre-senile dementia with hyaline degeneration of smaller brain blood vessels ...
... Alzheimer’s disease: is a brain disorder in elderly due to acetylcholine deficiency. It is characterized by pre-senile dementia with hyaline degeneration of smaller brain blood vessels ...
Addiction - Trollway Anesthesia
... survival. Readily influenced by long-term memory stores or anticipatory mechanisms. *important concept • Hedonism: Intrinsic value of pleasure. The only value is how much good is produced and how little pain is experienced (Encyclopedia Britannica, 11th ed., 1911). ...
... survival. Readily influenced by long-term memory stores or anticipatory mechanisms. *important concept • Hedonism: Intrinsic value of pleasure. The only value is how much good is produced and how little pain is experienced (Encyclopedia Britannica, 11th ed., 1911). ...
More Foundations (not in your book
... more other drugs Do not confuse with: – Adverse drug reaction - an undesirable drug effect from mild to severe – Drug incompatibility - chemical or physical reaction that occurs among two or more drugs outside the body Pharmacokinetic Interaction Absorption When a person takes two drugs at the s ...
... more other drugs Do not confuse with: – Adverse drug reaction - an undesirable drug effect from mild to severe – Drug incompatibility - chemical or physical reaction that occurs among two or more drugs outside the body Pharmacokinetic Interaction Absorption When a person takes two drugs at the s ...