NPS - NHS Ayrshire and Arran.
... Users can find it hard to distinguish reality from illusion. A number of plant-based hallucinogens, with a range of effects, can be bought in the UK. These include kratom and salvia. Some of these plant-based substances have been available for many years, but have received increased attention recen ...
... Users can find it hard to distinguish reality from illusion. A number of plant-based hallucinogens, with a range of effects, can be bought in the UK. These include kratom and salvia. Some of these plant-based substances have been available for many years, but have received increased attention recen ...
Chapter 26 - Ukiah Adult School
... What information should be included in the nurse’s teaching plan for educating Mr. Howard about his medication? ...
... What information should be included in the nurse’s teaching plan for educating Mr. Howard about his medication? ...
Antiarrhythmic Drugs
... ectopic activity. Drugs have antiarrhythmic properties by virtue of their β -receptor–blocking action and direct membrane effects Some of these drugs have selectivity for cardiac β 1 receptors e.g. metoprolol, Some have intrinsic sympathomimetic activity e.g. pindolol. Some have marked direct membra ...
... ectopic activity. Drugs have antiarrhythmic properties by virtue of their β -receptor–blocking action and direct membrane effects Some of these drugs have selectivity for cardiac β 1 receptors e.g. metoprolol, Some have intrinsic sympathomimetic activity e.g. pindolol. Some have marked direct membra ...
Pharmacodynamics - obsidian
... 1. Through enzymes: a drug can act by either stimulating or inhibiting an enzyme Through receptors: this is when a drug produces its response by attaching itself to a protein called as receptor which in turn regulates the cell function. Receptor action is the most commonest way of producing acti ...
... 1. Through enzymes: a drug can act by either stimulating or inhibiting an enzyme Through receptors: this is when a drug produces its response by attaching itself to a protein called as receptor which in turn regulates the cell function. Receptor action is the most commonest way of producing acti ...
New Psychoactive Substances – DAWG JUNE 2014
... “In the view of this author, it is likely that the future drugs of abuse will be synthetics rather than plant products. They will be synthesized from readily available chemicals, may be derivatives of pharmaceuticals, will be very potent, and often very selective in their action. In addition, they w ...
... “In the view of this author, it is likely that the future drugs of abuse will be synthetics rather than plant products. They will be synthesized from readily available chemicals, may be derivatives of pharmaceuticals, will be very potent, and often very selective in their action. In addition, they w ...
Interaction between the 5-HT system and the basal ganglia
... dyskinesias (LID), which have been related to adaptive changes of the serotonergic system. For example, a recent publication revealed that patients who had developed dyskinetic movements showed significant serotonergic hyperinnervation in the GPe and caudate, in comparison to non-dyskinetic individu ...
... dyskinesias (LID), which have been related to adaptive changes of the serotonergic system. For example, a recent publication revealed that patients who had developed dyskinetic movements showed significant serotonergic hyperinnervation in the GPe and caudate, in comparison to non-dyskinetic individu ...
The Neurobiology of Alcoholism: Insights from the Dark Side of
... Key Findings and Conclusions Acute reinforcing effects of drugs of abuse— depend on neurochemical substrates such as GABA, opioid peptides, serotonin, glutamate and dopamine in the ventral striatum of the basal forebrain. ...
... Key Findings and Conclusions Acute reinforcing effects of drugs of abuse— depend on neurochemical substrates such as GABA, opioid peptides, serotonin, glutamate and dopamine in the ventral striatum of the basal forebrain. ...
Pharmacology - faculty at Chemeketa
... • You are dispatched on a “chest pain” call. First responders are on scene and you arrive in 8 minutes. A woman meets you at the front door and tells you she is the patient’s wife; she takes you to the patient who is a 42 year old minister. He is CAO PPTE, but is in obvious distress. He is breathing ...
... • You are dispatched on a “chest pain” call. First responders are on scene and you arrive in 8 minutes. A woman meets you at the front door and tells you she is the patient’s wife; she takes you to the patient who is a 42 year old minister. He is CAO PPTE, but is in obvious distress. He is breathing ...
Document
... An adverse drug reaction may be defined as any unwanted response to a drug which is noxious, unintended and occurs at doses normally used for prophylaxis, diagnosis, or therapy. These reactions are mainly individual and thus closer attentions should be given to drugs with known adverse reactions. Ad ...
... An adverse drug reaction may be defined as any unwanted response to a drug which is noxious, unintended and occurs at doses normally used for prophylaxis, diagnosis, or therapy. These reactions are mainly individual and thus closer attentions should be given to drugs with known adverse reactions. Ad ...
Program Status
... marketed therapeutics, they provide opportunities for producing first-of-class drugs. A benefit of the program diversity is thsat it provides a hedges against drug development risks. Tularik has identified lead compounds for 27 of company-validated targets. Thirteen of these lead compounds are being ...
... marketed therapeutics, they provide opportunities for producing first-of-class drugs. A benefit of the program diversity is thsat it provides a hedges against drug development risks. Tularik has identified lead compounds for 27 of company-validated targets. Thirteen of these lead compounds are being ...
• • • • •
... • Aldosterone is a very powerful mineralocorticoid, but it has a week glucocorticoid activity. • Its release from the adrenal cortex is controlled by the renin-angiotensin system. • It acts on collecting tubules causing reabsorption of sodium, bicarbonate & water. Potassium & H + are lost in the uri ...
... • Aldosterone is a very powerful mineralocorticoid, but it has a week glucocorticoid activity. • Its release from the adrenal cortex is controlled by the renin-angiotensin system. • It acts on collecting tubules causing reabsorption of sodium, bicarbonate & water. Potassium & H + are lost in the uri ...
VIOXX (ROFECOXIB)
... There are no adequate trials in pregnant women. ROFETAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Like other NSAIDs, ROFETAB should be avoided in late pregnancy as it may cause premature closure of the ductus arteriosus. It is not known ...
... There are no adequate trials in pregnant women. ROFETAB should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Like other NSAIDs, ROFETAB should be avoided in late pregnancy as it may cause premature closure of the ductus arteriosus. It is not known ...
Anti-Arrhythmic Drugs
... Potassium Channel Blockers The hallmark of group 3 drugs is prolongation of the AP duration. This AP prolongation is caused by blockade of IK potassium channels that are responsible for the repolarization of the AP. AP prolongation results in an increase in effective refractory period and reduces th ...
... Potassium Channel Blockers The hallmark of group 3 drugs is prolongation of the AP duration. This AP prolongation is caused by blockade of IK potassium channels that are responsible for the repolarization of the AP. AP prolongation results in an increase in effective refractory period and reduces th ...
Healing the Addicted Brain - National Association of Addiction
... death in the US behind cancer and heart disease ...
... death in the US behind cancer and heart disease ...
Chapt13 Lecture 13ed Pt 4
... Drug abuse: Methamphetamine • Powder form is called speed and crystal form is called meth or ice. • It is a stimulant that reverses the effects of _______ and is a mood elevator. • High agitation is common after the rush and can lead to violent behavior. • Methamphetamine causes psychological depend ...
... Drug abuse: Methamphetamine • Powder form is called speed and crystal form is called meth or ice. • It is a stimulant that reverses the effects of _______ and is a mood elevator. • High agitation is common after the rush and can lead to violent behavior. • Methamphetamine causes psychological depend ...
Narcotic analgesics
... (thalamus, hypothalamus, limbic system). Opioid receptors are grouped into the following four classes: 1- Mu- found in pain-regulating areas of the brain; contribute to analgesia, euphoria, respiratory depression, physical dependence and hypothermic actions. 2- Kappa- found in the cerebral cortex an ...
... (thalamus, hypothalamus, limbic system). Opioid receptors are grouped into the following four classes: 1- Mu- found in pain-regulating areas of the brain; contribute to analgesia, euphoria, respiratory depression, physical dependence and hypothermic actions. 2- Kappa- found in the cerebral cortex an ...
Cultural, Legal, and Ethical Considerations
... Drugs with an abuse risk lower than Schedule II. These drugs also have safe and accepted medical use in the US. Drugs may contain safer and small amounts of certain narcotic and non-narcotic drugs, anti-anxiety, tranquilizers, sedatives, stimulants, and nonnarcotic analgesics. ...
... Drugs with an abuse risk lower than Schedule II. These drugs also have safe and accepted medical use in the US. Drugs may contain safer and small amounts of certain narcotic and non-narcotic drugs, anti-anxiety, tranquilizers, sedatives, stimulants, and nonnarcotic analgesics. ...
Prescriptions Drugs 101
... drug that reaches the bloodstream. What determines bioavailability? ◦ Physical properties of the drug like its charge, and whether it is water- or fat-soluble ◦ Drug formulation: immediate release or timed release ◦ Drug administered on a full or empty stomach ...
... drug that reaches the bloodstream. What determines bioavailability? ◦ Physical properties of the drug like its charge, and whether it is water- or fat-soluble ◦ Drug formulation: immediate release or timed release ◦ Drug administered on a full or empty stomach ...
Selected module tests in Pharmacology
... 22. Piracetam is characterized by: A. Increased tolerance of the brain to hypoxia. B. Improved memory. C. Stimulation of ATP synthesis in CNS. D. Rapidly achieved effect. 23. Point out the correct statements concerning morphine: A. Activates μ, κ and δ opioid receptors. B. Blocks μ receptors. C. Psy ...
... 22. Piracetam is characterized by: A. Increased tolerance of the brain to hypoxia. B. Improved memory. C. Stimulation of ATP synthesis in CNS. D. Rapidly achieved effect. 23. Point out the correct statements concerning morphine: A. Activates μ, κ and δ opioid receptors. B. Blocks μ receptors. C. Psy ...
Chapter 16
... How Drugs Work • Many drugs act by interacting with specific cells in the body that carry receptors, which are proteins on the surface or inside a cell to which a drug or natural substance can bind and affect cell function. • When a drug binds to a receptor, it affects the biological processes of c ...
... How Drugs Work • Many drugs act by interacting with specific cells in the body that carry receptors, which are proteins on the surface or inside a cell to which a drug or natural substance can bind and affect cell function. • When a drug binds to a receptor, it affects the biological processes of c ...
Pharmacology 6 – SNS Antagonists
... 1. Name common examples of non-selective and selective SNS antagonists and what are they clinically used for. 2. How do SNS antagonists produce their anti-hypertensive effects and what are their side effects. 3. Compare the effects produced by selective and non-selective antagonists, name examples o ...
... 1. Name common examples of non-selective and selective SNS antagonists and what are they clinically used for. 2. How do SNS antagonists produce their anti-hypertensive effects and what are their side effects. 3. Compare the effects produced by selective and non-selective antagonists, name examples o ...
Document
... -poor metabolizers no pain relief from codeine prodrug for morphine catalyzed by CYP2D6 4-hydroxylase Other genetic variations- 1:3000 occurrence atypical cholinesterasewill not metabolize topical anasthetic succinycholine these individuals may stay “frozen” for days or weeks- need to be screened fo ...
... -poor metabolizers no pain relief from codeine prodrug for morphine catalyzed by CYP2D6 4-hydroxylase Other genetic variations- 1:3000 occurrence atypical cholinesterasewill not metabolize topical anasthetic succinycholine these individuals may stay “frozen” for days or weeks- need to be screened fo ...
Foundations in Microbiology - Houston Community College System
... • may block synthesis of nucleotides, inhibit replication, or stop transcription • Sulfonamides and trimethoprim block enzymes required for tetrahydrofolate synthesis needed for DNA & RNA synthesis. • competitive inhibition – drug competes with normal substrate for enzyme’s active site • synergistic ...
... • may block synthesis of nucleotides, inhibit replication, or stop transcription • Sulfonamides and trimethoprim block enzymes required for tetrahydrofolate synthesis needed for DNA & RNA synthesis. • competitive inhibition – drug competes with normal substrate for enzyme’s active site • synergistic ...
Common Side Effects of Drug - WCCS E
... The relationship and consequences of adaptive processes to drug abuse. The processes discussed in the text are highlighted in the figure. ...
... The relationship and consequences of adaptive processes to drug abuse. The processes discussed in the text are highlighted in the figure. ...