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toxicology 3 - Calgary Emergency Medicine
toxicology 3 - Calgary Emergency Medicine

... • GABA is broken down by GABA transaminase  this is exploited by the anticonvulsant Vigabatrin which inhibits GT • 3-types of GABA rec (A [main one], B & C). • GABA B rec affected by GHB (drug of abuse) and Baclofen (antispasmodic) – in someone with Sz and a Baclofen pump think pump failure) ...
Brain--Food
Brain--Food

... drugs is their potential for significantly affecting brain activity with a minimum of undesirable side effects. Very often the nutrients have their effect on the brain in about the same dose as a person would consume in normal eating. However, for these nutrients be most effective, they must typical ...
What is “Krokodil”? - Maryland Poison Center
What is “Krokodil”? - Maryland Poison Center

... What is “Krokodil”? “Krokodil” (also known as “Crocodil” or “Kroc”) is a slang term for desomorphine, a homemade opioid analgesic. It is used as a heroin substitute, primarily in Russia where heroin is expensive and in short supply. Estimates of Krokodil users in Russia have ranged from more than 10 ...
Pharmacology of Enteral Agents
Pharmacology of Enteral Agents

... the potential benefits justify the potential risks to the fetus D—there is positive evidence of fetal risk. If the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective X—the drug is contraindicated in women who are or may bec ...
Slide 1 - edl.io
Slide 1 - edl.io

Slide 1
Slide 1

... Gas chromatography has one major drawback: It does not give a specific identification. Mass spectrometry cannot separate mixtures. By combining the two (GC-MS), constituents of mixtures can be specifically identified. ...
Chapter 7 PPT
Chapter 7 PPT

... Gas chromatography has one major drawback: It does not give a specific identification. Mass spectrometry cannot separate mixtures. By combining the two (GC-MS), constituents of mixtures can be specifically identified. ...
Personal-Psychopath-treatment2
Personal-Psychopath-treatment2

... • We know a lot and we know a little • We are aware of what we know: it’s as if we shine a flashlight on the world of behavior – How to treat behavioral/mental problems is an ex. ...
NIDA Commonly Abused Prescription Drug Chart
NIDA Commonly Abused Prescription Drug Chart

... ** Taking drugs by injection can increase the risk of infection through needle contamination with staphylococci, HIV, hepatitis, and other organisms. Injection is a more common practice for opioids, but risks apply to any medication taken by injection. ...
07 Rhinitis & cough
07 Rhinitis & cough

... • 1st & 2nd generation antihistamines are competitive inhibitors of H1- receptor mediated responses. • Many of the 1st generation drugs have effects that are not mediated by H1- receptors. • Such as antimuscarinic activity, alpha adrenoceptors blocking, serotonin receptors antagonism & local anesthe ...
The Mirror Neuron System and Its Role in Understanding the Others
The Mirror Neuron System and Its Role in Understanding the Others

... series of data that indicate that our brain is endowed with a specific mechanism –mirror mechanism- that enables us to understand all these aspects of others’ behavior. I will show first that, for the so-called “cold” actions (those devoid of a emotional content), the mirror mechanism is localized i ...
“Wiring” Your Brain - Scholastic Heads Up
“Wiring” Your Brain - Scholastic Heads Up

... connections that are not used. This ability of the brain to modify its circuitry is strongest in the teen years. This means that it is easier for you—as a teen—to learn something new and remember it, such as a foreign language, than it is for an adult. It also means that teens can shape who they wil ...
MSG – Friend or Foe - Rosenthal David DC
MSG – Friend or Foe - Rosenthal David DC

... are irreversible and can result from a SINGLE exposure of these products in sufficient concentration? How would you feel when you learn the food industry hides and disguises these excitotoxin additives (MSG and Aspartate) so they can't be recognized? Incredulous? Enraged? The fact is many foods are ...
Commonly Abused Drugs
Commonly Abused Drugs

Drugs for Parkinsonism
Drugs for Parkinsonism

... patients with a fluctuating or declining response. • Given with breakfast and lunch, and may cause insomnia if taken later during the day. ...
patterns of drug-induced liver disease
patterns of drug-induced liver disease

...  Flutamide causes a mix of lesions that appear at or about the fortyeighth week of treatment.  Niacin in doses greater than 3 g/day, or in doses greater than 1 g/day of sustained-release formulations, causes the same mixed pattern of damage. NEOPLASTIC DISEASE  Both carcinoma- and sarcoma-like le ...
Nitenpyram - Cloudfront.net
Nitenpyram - Cloudfront.net

... Nitenpyram is a systemic neonicotinoid that binds to specific nicotinic acetylcholine receptors, thereby interfering with normal nerve transmission in the flea and killing it.1,2 The neurotransmitter acetylcholine is a key chemical in communication between synapses. In a normally functioning nerve, ...
Antiamoebic Drugs
Antiamoebic Drugs

... Antiamoebic Drugs • (one strategy for treating luminal amebiasis is to add antibiotics, such as tetracyclines to the treatment regimen, resulting in a reduction in intestinal flora – the amoeba’s major food source). • The trophozoites within the intestine are slowly carried toward the rectum, where ...
The Slippery Slope of Relieving Pain: Be Wary of Opioid Drugs
The Slippery Slope of Relieving Pain: Be Wary of Opioid Drugs

... painkillers—opioids, also referred to as narcotics. If you have been injured on the job and have developed chronic pain, you might seek relief with narcotic medications. Narcotics are potent pain relievers. But there are many reasons why you should try safer medications before taking narcotics. Pres ...
Click Here to View
Click Here to View

... Both Suboxone and Subutex are known for its potential for abuse and diversion Suboxone and Subutex can be injected intravenously and used for treatment to get “High” Intravenous use of either one of those drugs can, and is known to cause death When Suboxone/ Subutex is taken with other controlled d ...
STRUCTURAL ACTIVITY RELATIONSHIP AMONG THE
STRUCTURAL ACTIVITY RELATIONSHIP AMONG THE

... salivation, loss of binocular accommodation, miosis ...
Medications - Delaware Association of Home and Community Care
Medications - Delaware Association of Home and Community Care

... (incr. unbound drugs in liver-protein bound drugs warfarin, salicylic acid, dilantin, diazepam) ...
File
File

... increase risk of GI bleed w/ NSAIDs, phenobarb and phenytoin induce CYP450 enzymes that increase excretion of donepezil (decreased effect) pt teaching pointsEmphasize importance of adhering to medication regiment, omit missed doses and return to schedule the following day; drug effects may take week ...
A New Assault on Addiction
A New Assault on Addiction

... finishing the process, the young woman awoke briefly, demanding to know why no one had started the treat ...
The Drug development process
The Drug development process

... • The majority of such targets are proteins (mainly enzymes, hormones, ion channels and nuclear receptors). • Additionally, present in the sequence data of many human pathogens is sequence data of hundreds, perhaps thousands, of pathogen proteins that could serve as drug targets against those pathog ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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