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AN INDIVIDUAL BASED STUDY OF THE GERIATRIC POPULATION: A POLYPHARMACY
AN INDIVIDUAL BASED STUDY OF THE GERIATRIC POPULATION: A POLYPHARMACY

... by pulmonology and Amidorane by cardiology departments whereas inappropriateness was very high in a General medicine. Our article suggests that current practice in our hospital associated with greater polypharmacy and irrational use of drugs. In future, multidisciplinary approach, steps to be taken ...
Presentation - Direct Relief
Presentation - Direct Relief

... • No place for topical treatment • Treat empirically with systemic drugs • Azoles are first-line of therapy – Fluconazole included in class ...
NEUROCHEMICAL SELVES
NEUROCHEMICAL SELVES

... Pakistan over 130%. In the "more developed" regions, Japan has grown by almost 50% from an initially low base level of sales; in Europe, from a relatively high base, growth has been over 125%; and growth in the value of sales in the United States been over 600%. Within these regions, the value of ps ...
LC/MS for Clinical Toxicology
LC/MS for Clinical Toxicology

... Patient 1: Serum 5-OP= 35.8 mmol/L Urine 5-OP= 0.65 mmol/mmol Cr Patient 2: Urine 5-OP= 0.1 mmol/mmol Cr ...
File
File

...  1. What disease is being treated? What is the extent/severity of the illness?  2. What are the drugs being prescribed? What drugs have the patient received to date?  3. Does the patient have any insufficiency of the renal, hepatic, or cardiac system?  4. For drugs with renal elimination, what a ...
Plaquenil (hydroxychloroquine sulfate)
Plaquenil (hydroxychloroquine sulfate)

... There is a theoretical risk of inhibition of intra-cellular αgalactosidase activity when PLAQUENIL is co-administered with agalsidase. PLAQUENIL may also be subject to several of the known interactions of chloroquine even though specific reports have not appeared including potentiation of its direct ...
SULFONAMIDES and TRIMETHOPRIM
SULFONAMIDES and TRIMETHOPRIM

... • This drug is structurally similar to folic acid. • It is a weak base and is trapped in acidic environments, reaching high concentrations in prostatic and vaginal fluids. • A large fraction of trimethoprim is excreted unchanged in the urine. ...
OPIOIDS
OPIOIDS

... prescribing opiates for pain became more common during the last decade of the 20th Century • Opioid therapy became accepted (although often inadequately) for treating acute pain, pain due to cancer, & pain caused by a terminal disease • Still disputed is the use of opioids for chronic pain not assoc ...
Slide 1 - Gordon State College
Slide 1 - Gordon State College

... progressive (use of licit drugs before using illicit drugs) -Precipitating factors -Social consequences of use ...
幻灯片 1 - shsmu.edu.cn
幻灯片 1 - shsmu.edu.cn

... Multiinfarct dementia: Numerous small cerebral vascular accidents, most commonly caused by atherosclerotic disease, leading to dementia. Normal pressure hydrocephalus: Reversible form of dementia where the cerebral ventricles slowly enlarge as a result of disturbances to cerebral spinal fluid resorp ...
IC-50 Research Service
IC-50 Research Service

... Provider of Global Contract Research Services Accelerating Preclinical Research, Drug Discovery & Therapeutics ...
Symptom Management in End-of-Life Care
Symptom Management in End-of-Life Care

...  Difficult to dose correctly  Slow onset/offset of action  Difficult to respond to changing pain  Dependent on physiological state of patient  Cachexia  Dehydration  Fever  Diaphoresis ...
Inhalants - Addictions Foundation Manitoba
Inhalants - Addictions Foundation Manitoba

... more quickly and efficiently than by ingesting, snorting or injecting because of the large surface area available for the chemical agents to be absorbed into the bloodstream. This is especially true if the molecules in the drug are lipid soluble, which facilitates crossing cell membranes and enterin ...
Olney JW. Brain lesions, obesity, and other disirbances in mice
Olney JW. Brain lesions, obesity, and other disirbances in mice

... In addition to the disturbances in mice, I discovered in 1969 that glutamate (Glu) damages the infant brain when administered orally, that several species, including monkeys, are susceptible, and that large amounts of Glu were being added to baby foods. These findings, when conveyed to a US Senate I ...
Drugs for Neoplasia
Drugs for Neoplasia

... prostatic acid phosphatase (PAP), an antigen associated with prostate cancer. Men who had a specific type of metastatic prostate cancer received Sipuleucel-T demonstrated an added survival of by about 4 months (19). • The U.S. Food Drug Administration (FDA) has approved two new vaccines, Gardasil® a ...
Drugs Affecting the Central Nervous System
Drugs Affecting the Central Nervous System

... Italian Americans are very dramatic about their pain Jewish Americans complain a lot about pain. African Americans report higher levels of chronic pain and have a greater sensitivity to acute pain. Asian Americans do not express their pain. ...
(sulpiride) loading on to the PBCA nanoparticles will be calculated
(sulpiride) loading on to the PBCA nanoparticles will be calculated

... diminished social engagement). The latter predominate in one third of Schizophrenic population and are associated with a poor long term outcome and a poor response to drug treatment23. ...
Practice Exam for Pharmacology Exam 1 – Lectures 1
Practice Exam for Pharmacology Exam 1 – Lectures 1

... b. Urine alkalinization – you would want to prescribe an alkalizer because Asprin is an acid and would be ionized in a base and thus excreted. If it was induced acidification it would be non-ionized and better absorbed and we want to excrete it, not absorb it. c. Neither, Asprin isn’t excreted large ...
PDF - the Idaho RADAR Center Library
PDF - the Idaho RADAR Center Library

... This trend currently is most popular overseas, but can also be found in the U.S. Young drinkers have started snorting vodka. The result is that the alcohol goes directly to the brain rather than being filtered through the liver. Immediate effects such as passing out, brain damage and even fatality a ...
Nimulid Tablet - Panacea Biotec
Nimulid Tablet - Panacea Biotec

... Mechanism of Action Nimesulide is a sulfonanilide non-steroidal anti-inflammatory drug whose anti-inflammatory analgesic and antipyretic activities have been demonstrated in several widely used animal experimental models2. At the recommended dose of 100 mg b.i.d., it is as effective an analgesic and ...
Respiratory Pharmacology
Respiratory Pharmacology

... – Toxicity: NVD, restlessness, dysrhythmias, seizures – Interactions: caffeine, Tagamet, fluoroquinolones, other CNS drugs ...
Site-specific molecular design and its relevance to
Site-specific molecular design and its relevance to

... molecules that elute at different rates from the protein matrix using in-line mass spectrometry.34 In summary, we can expect these techniques to elucidate the structural features characteristic of protein–protein and protein–small molecule interactions, and to provide a fundamental data set from whi ...
Acute Pain Management - Anesthesiology and Perioperative Medicine
Acute Pain Management - Anesthesiology and Perioperative Medicine

...  Alleviation ...
Serotonin syndrome - Exeter Headache Clinic
Serotonin syndrome - Exeter Headache Clinic

... were lost to follow-up, 10 patients failed to achieve 50% reduction, 6 stopped because of side-effects and 3 withdrew. DVP-26/51(51%) of patients had greater than 50% reduction.8 were lost to follow-up, 3 failed to achieve a 50% reduction and 10 stopped due to side-effects and 4 withdrew. From this ...
Prion Diseases - Winona State University
Prion Diseases - Winona State University

... Disease causing prion is a modified form of a normal cellular protein known as PrPc. This normal form is protease sensitive so it does not accumulate. The modified prion is known as PrPsc (for scrapie) which is relatively resistant to proteases and accumulates in cytoplasmic vesicles of diseased ind ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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