Organism
... Stops pulses of GnRH – ↑ LH & FSH release Long term = Shuts down release of LH & FSH Also for: BPH, Breast Cancer & PMS ...
... Stops pulses of GnRH – ↑ LH & FSH release Long term = Shuts down release of LH & FSH Also for: BPH, Breast Cancer & PMS ...
Vol 11, Issue 3: Toxicology Screening
... over-the-counter cold medications. There are immunoassays specific for methamphetamine that will not cross-react with OTC stimulant amines. ...
... over-the-counter cold medications. There are immunoassays specific for methamphetamine that will not cross-react with OTC stimulant amines. ...
Chronobiology: Pulsatile Drug Delivery System
... controlling the drug delivery in both space and time such that non-targeted tissues are not adversely affected. Dox activity can be enhanced by ultrasound in one region, while in an adjacent region there is little or no effect of the drug. 3.3. Electric field induces release Electrically responsive ...
... controlling the drug delivery in both space and time such that non-targeted tissues are not adversely affected. Dox activity can be enhanced by ultrasound in one region, while in an adjacent region there is little or no effect of the drug. 3.3. Electric field induces release Electrically responsive ...
Polyesters and polyester carbonates for controlled drug delivery
... Conventional therapeutic systems suffer from many drawbacks, including adverse effects, strongly fluctuating drug levels in the body, poor drug efficacy and poor patient compliance [1]. Additionally, there has been increased interest in drug delivery due to (i) the emergence of low-molecular-weight ...
... Conventional therapeutic systems suffer from many drawbacks, including adverse effects, strongly fluctuating drug levels in the body, poor drug efficacy and poor patient compliance [1]. Additionally, there has been increased interest in drug delivery due to (i) the emergence of low-molecular-weight ...
... available as over-the-counter preparations, whereas others, such as hydroxyzine, are available by prescription. poor receptor selectivity for the H1-receptor and block muscarinic receptors, causing substantial anticholinergic effects dry mouth, constipation, urinary retention, and tachycardia, and c ...
Alcohol and Other Drug Emergencies
... • Become familiar with dealing with severe alcohol withdrawal and acute complications of alcohol addiction • Recognise and manage opioid withdrawal • Develop an approach to ED assessment of less acute alcohol related and appropriate referral ...
... • Become familiar with dealing with severe alcohol withdrawal and acute complications of alcohol addiction • Recognise and manage opioid withdrawal • Develop an approach to ED assessment of less acute alcohol related and appropriate referral ...
... trapped by covalently (but reversibly) linked topoisomerases, the function of which is compromised26–28. As a result of quinolone–topoisomerase–DNA complex formation, the DNA replication machinery becomes arrested at blocked replication forks, leading to inhibition of DNA synthesis, which immediatel ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... brain. While anyone can experience a seizure under the appropriate pathophysiological conditions, epilepsy suggests an enduring alteration of brain function that facilitates abnormal neuronal firing. The aberrant electrical activity that underlies epilepsy is the result of biochemical processes at t ...
... brain. While anyone can experience a seizure under the appropriate pathophysiological conditions, epilepsy suggests an enduring alteration of brain function that facilitates abnormal neuronal firing. The aberrant electrical activity that underlies epilepsy is the result of biochemical processes at t ...
The Unintended Consequences of Regulating
... would simply adjust their smoking behavior to return their blood and brain nicotine concentrations to their set-point level by increasing the volume and depth of inhalations or the number of cigarettes smoked in a given period of time. The extent to which the smoker uses one or both of these methods ...
... would simply adjust their smoking behavior to return their blood and brain nicotine concentrations to their set-point level by increasing the volume and depth of inhalations or the number of cigarettes smoked in a given period of time. The extent to which the smoker uses one or both of these methods ...
Cocaine - drug info @ your library
... In its pure form, cocaine is a white crystalline powder called cocaine hydrochloride. Cocaine hydrochloride cannot be smoked effectively because it is destroyed at high temperatures; however, if the hydrochloride is removed through a chemical process the drug is converted into freebase, which can b ...
... In its pure form, cocaine is a white crystalline powder called cocaine hydrochloride. Cocaine hydrochloride cannot be smoked effectively because it is destroyed at high temperatures; however, if the hydrochloride is removed through a chemical process the drug is converted into freebase, which can b ...
Guidance for Industry Drug Metabolism/Drug Interaction Studies in the Drug Development
... During studies to identify metabolic routes of elimination for an investigational new drug, microsomes from several donors should be used, either individually or pooled, to avoid reliance on microsomes that are deficient in one or more metabolic pathways, unless this is a specific objective of the s ...
... During studies to identify metabolic routes of elimination for an investigational new drug, microsomes from several donors should be used, either individually or pooled, to avoid reliance on microsomes that are deficient in one or more metabolic pathways, unless this is a specific objective of the s ...
ENGLISH VERSION (Eng)
... animals [12]. As “Grünenthal” records were destroyed, we will never know how thalidomide’s safety was studied [13]. It is known that the Food and Drug Administration (USA) experts considered data given by the manufacturer on the drug’s safety obtained in experiments on animals insufficient and uncon ...
... animals [12]. As “Grünenthal” records were destroyed, we will never know how thalidomide’s safety was studied [13]. It is known that the Food and Drug Administration (USA) experts considered data given by the manufacturer on the drug’s safety obtained in experiments on animals insufficient and uncon ...
Amebiasis
... Plasma concentrations of praziquantel increase when the drug is taken with a high-carbohydrate meal. It increases the permeability of cell membranes to calcium, resulting in paralysis, dislodgement, and ...
... Plasma concentrations of praziquantel increase when the drug is taken with a high-carbohydrate meal. It increases the permeability of cell membranes to calcium, resulting in paralysis, dislodgement, and ...
THE HORMESIS OF NAGAPARPAM IN EXPERIMENTALLY INDUCED PYELONEPHRITIC MICE Research Article
... Objective Nagaparpam (NP), a herbo-mineral based Siddha medicine is widely used across the various parts of India for the treatment of various gastric ailments and other kidney related diseases. The lack of scientific evidence regarding the toxicity and efficacy of this drug upon prolonged usage by ...
... Objective Nagaparpam (NP), a herbo-mineral based Siddha medicine is widely used across the various parts of India for the treatment of various gastric ailments and other kidney related diseases. The lack of scientific evidence regarding the toxicity and efficacy of this drug upon prolonged usage by ...
File
... desired site of action. A Local Effect: occurs when the drug activity is at the site of administration (e.g. eyes, ears, nose, skin). A Systemic Effect: occurs when the drug is introduced into the circulatory system by any route of administration and carried by the blood to the site of action. ...
... desired site of action. A Local Effect: occurs when the drug activity is at the site of administration (e.g. eyes, ears, nose, skin). A Systemic Effect: occurs when the drug is introduced into the circulatory system by any route of administration and carried by the blood to the site of action. ...
HYOSCYAMINE - Capellon Pharmaceuticals
... Geriatric patients are especially susceptible to the anticholinergic side effects, such as constipation, dryness of mouth, and urinary retention (especially in males). If these side effects occur and continue or are severe, medication should probably be discontinued. Caution is also recommended when ...
... Geriatric patients are especially susceptible to the anticholinergic side effects, such as constipation, dryness of mouth, and urinary retention (especially in males). If these side effects occur and continue or are severe, medication should probably be discontinued. Caution is also recommended when ...
Lebanus Cedra LebanusCedra
... Oxysterols are oxygenated derivatives of cholesterol. Some of these compounds may be toxic and even oncogenic while others seem promising as anticancer drugs. Advanced recurrent or refractory non-Hodgkin lymphomas (NHLs) have a dismal prognosis and are treated palliatively. (24-ethyl-cholestane- 3β, ...
... Oxysterols are oxygenated derivatives of cholesterol. Some of these compounds may be toxic and even oncogenic while others seem promising as anticancer drugs. Advanced recurrent or refractory non-Hodgkin lymphomas (NHLs) have a dismal prognosis and are treated palliatively. (24-ethyl-cholestane- 3β, ...
Acetazolamide Acetazolamide sodium
... Sulfonamide derivative possessing carbonic anhydrase inhibitor activity. Anticonvulsant effects may be due to (1) inhibition of carbonic anhydrase in the CNS, which increases carbon dioxide tension resulting in a decrease in neuronal conduction, and (2) systemic acidosis. As a diuretic, the drug inh ...
... Sulfonamide derivative possessing carbonic anhydrase inhibitor activity. Anticonvulsant effects may be due to (1) inhibition of carbonic anhydrase in the CNS, which increases carbon dioxide tension resulting in a decrease in neuronal conduction, and (2) systemic acidosis. As a diuretic, the drug inh ...
Document
... methadone, meperidine (Demerol) and hydrocodone (Vicodine). The most common drug diverted from the healthcare facility setting are opioids. ...
... methadone, meperidine (Demerol) and hydrocodone (Vicodine). The most common drug diverted from the healthcare facility setting are opioids. ...
Antifungals - ACH Pediatric Residents
... PO only so far, cherry suspension, tablet form poorly absorbed compared to susp ...
... PO only so far, cherry suspension, tablet form poorly absorbed compared to susp ...
Thai FDA - cri.or.th
... Acquired Immune Deficiency Syndromes (AIDS) is an important disease in this century. Many scientists are searching for a way to cure this disease, but until today a treatment for AIDS has not been discovered. Drug Companies continue to look for a drug that can be used to cure this disease already th ...
... Acquired Immune Deficiency Syndromes (AIDS) is an important disease in this century. Many scientists are searching for a way to cure this disease, but until today a treatment for AIDS has not been discovered. Drug Companies continue to look for a drug that can be used to cure this disease already th ...
Sleep - cloudfront.net
... – Drug Tolerance: Reduction in body’s response to a drug – Withdrawal Symptoms: Physical illness following withdrawal of the drug ...
... – Drug Tolerance: Reduction in body’s response to a drug – Withdrawal Symptoms: Physical illness following withdrawal of the drug ...
2.5 Other Antihypertensive Drugs - Doncaster and Bassetlaw Hospitals
... is, however, a safe option for use in pregnancy. Doxazosin is used for treatment of hypertension where other drugs have failed to control blood pressure, or in patients with contraindications to other antihypertensive drugs. Alpha-blockers have post-synaptic alpha-blocking and vasodilator properties ...
... is, however, a safe option for use in pregnancy. Doxazosin is used for treatment of hypertension where other drugs have failed to control blood pressure, or in patients with contraindications to other antihypertensive drugs. Alpha-blockers have post-synaptic alpha-blocking and vasodilator properties ...
Extemporaneous formulations-problems and solutions
... used in their research. This information is often omitted from the publication and can be extremely difficult to source especially when required rapidly. Investigators engaged in stability studies should aim to make the results of their research universally acceptable by designing simple formulation ...
... used in their research. This information is often omitted from the publication and can be extremely difficult to source especially when required rapidly. Investigators engaged in stability studies should aim to make the results of their research universally acceptable by designing simple formulation ...