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PowerPoint-Präsentation
PowerPoint-Präsentation

... Currently, anxiety is one of the most common mental disorders affecting humanity and its prevalence is increasing. Anxiolytic substances occupy a prominent post in the ranking of the most utilized drugs by man. However, the anxiolytic drugs have an unfavorable risk/benefit ratio, especially benzodia ...
PLEXION® Cleanser - Mission Pharmacal
PLEXION® Cleanser - Mission Pharmacal

... fatty acids. INDICATIONS: This product is indicated for use in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis. CONTRAINDICATIONS: This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product. This product i ...
Hydroxyzine-Induced Dystonia
Hydroxyzine-Induced Dystonia

... gastro-intestinal tract with a peak blood-level of about two hours after oral administration [3]. Common adverse-effects of hydroxyzine in children include adverse central nervous system effects, causing sedation, decreased cognitive function and increased subjective somnolence [4]. However a few ca ...
Medication Supported Recovery
Medication Supported Recovery

... agonists. While the buprenorphine's effects diminish (20-60 hours), the patient may require higher opioid doses to compete with the presence of buprenorphine on mu-opioid receptors. The patient should be monitored carefully in the initial period to titrate the opioid agonist dose downward as its eff ...
Ten possible questions for the person with
Ten possible questions for the person with

... class at a low dose, rather than increasing the dose of the first drug. If this does not control blood pressure and both drugs are tolerated, incrementally increase the dose of one drug (other than a low dose thiazide diuretic) to the maximum recommended dose before increasing the dose of the other ...
In Vitro
In Vitro

... these compounds for our small molecule screen was based on mRNA expression levels reported previously for pHGG and DIPG, but we did not analyze the expression of the targeted proteins in our cells in detail [16]. Thus, these drugs may prove more effective when targeted agents are chosen based on ind ...
Document
Document

... This provision requires the front-end utilization of Generic medications covered under Tiers 1 & 2 at the beginning of a drug treatment program for new prescriptions. This requirement supports a continued focus on achieving higher generic drug utilization levels and reducing costs of the ...
ANTI-INFLAMMATORY ACTIVITY OF PLANTAGO EROSA WALL EXTRACTS IN RATS
ANTI-INFLAMMATORY ACTIVITY OF PLANTAGO EROSA WALL EXTRACTS IN RATS

... 0.5 x 0.5 cm and weighing 20±1 mg were sterilized at 1200c for 2 hours. They were then soaked in 0.2 ml distilled water containing penicillin (0.1 mg) and streptomycin (0.13 mg) and then inserted in both axillas an ether anaesthetized rat. While rats from the treated groups were treated with the tes ...
Clinical Pharmacology 1 - M
Clinical Pharmacology 1 - M

... • Typically crossover, single dose study in healthy subjects; measure extent and rate of absorption of parent drug and major active metabolites (if any) – Can assess relative (one formulation vs. another) or absolute (vs. IV formulation) bioavailability Information gained: ...
O A RIGINAL RTICLE
O A RIGINAL RTICLE

... the parasite are the artemisinin and its derivatives. Artemisinin and its derivatives are the most rapidly acting of all the current antimalarial drugs and they are highly efficacious against multi-drug resistant P. falciparum [25,42]. Development of resistance to artemisinin monotherapy [35], has p ...
Interactions between five candidate genes and antihypertensive
Interactions between five candidate genes and antihypertensive

... drug interactions was significant with GNB3 in diuretic users. There are some explanations why our results might be false-positive. First, we have tested multiple genes on multiple outcomes and if we had adjusted for multiple testing, the interaction between GNB3 and diuretic use would not have been ...
recent advances in animal models of drug addiction
recent advances in animal models of drug addiction

... these procedures, self-administration of a drug is incorporated into a multiple component schedule with other reinforcers. Studies using these procedures have shown that the contingencies for concurrent reinforcers can affect behavior asymmetrically and that the response requirement for reinforcers ...
Endocrinology 3a – Hyperthyroid Disorders
Endocrinology 3a – Hyperthyroid Disorders

...  Cytotoxic, almost selectively on thyroid follicular cells by virtue of irradiating βparticles which have a very short rage (γ- particles have a long range and pass straight through the tissue)  Negligible cytotoxicity when used as tracer doses for thyroid function tests Pharmacokinetics  Give as ...
Chemical Teratogenesis
Chemical Teratogenesis

... • Mucosal injury (water insoluble ...
Chemical Structure of Donepezil Pharmacokinetics
Chemical Structure of Donepezil Pharmacokinetics

... that are associated with significant losses of presynaptic cholinergic function in the brain. Donepezil enhances cholinergic transmission by reducing the enzymatic degradation of acetylcholine. Donepezil is 1200 times more selective for acetylcholinesterase rather than butylcholinesterase. ...
L5-oxytocics& tocolytics
L5-oxytocics& tocolytics

... Delay delivery for 48 hrs , this time can be used to administer glucocorticoids ( Injection betamethasone) to mother for maturation of the fetal lung To make it possible that baby is born where facility of neonatal ICU is available ...
Lecture6_RW
Lecture6_RW

... IC50 does not necessarily say anything about the thermodynamics of binding. IC50 tells you how concentrated your solution with respect to ligand has to be in order for 50% of the receptors to be bound. If you have poor binding, you will need a large concentration to start filling up receptor bindi ...
Slide 1 - Texas Tech University Health Sciences Center
Slide 1 - Texas Tech University Health Sciences Center

... Education Program is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation. Provider approved by California Board of Registered Nursing, Provider #CEP11800, for the designated number of contact hours for each program. Provi ...
Brand-Name vs Generic Finasteride Jan-Feb 2016
Brand-Name vs Generic Finasteride Jan-Feb 2016

... is the central ingredient. The second is known as the excipient, which is the inactive substance that serves as the vehicle for the API itself. If the drug is in a syrup form, then the excipient is the liquid that has been used to make it as such.² APIs are commonly referred to as “bulk pharmaceutic ...
Indigenous drug combination in the treatment of rhinosinal infections
Indigenous drug combination in the treatment of rhinosinal infections

... Moringa pterygosperma (Sonjna): The root bark of young trees contains a physiologically active basic principle “Spirochin” and an antibiotic substance “Pterygospermin”. Spirochin is effective in combating Gram-positive infections specially staphylococcal and streptococcal. It promotes epithelializat ...


... It consequently seemed logical to examine the effects of psychoactive drugs on the immune system’s responses. A wide variety of neural opioid receptors are closely involved in behavioural changes (Rance, 1983). The relationship between endogenous morphine and stress suggests that endorphins and enke ...
Transdermal Patches a successful tool in Transdermal
Transdermal Patches a successful tool in Transdermal

... Transdermal drug delivery system may produce unstable matrices if the loading dose is greater than 10 mg. For preparation of aluminium backed film, chloroform is the choice of solvent, because most of the drugs as well as adhesives are soluble in chloroform. The drug is dissolved in chloroform and a ...
Gastro-intestinal System - Eastbourne, Hailsham and Seaford CCG
Gastro-intestinal System - Eastbourne, Hailsham and Seaford CCG

... 1.3 Ulcer healing drugs ...
Slide 1
Slide 1

... NM-cholinoceptors. They depolarize muscle endplates by opening Na+ channels (just as ACh does) and initially produce twitching and fascilations. These drugs do not dissociate rapidly from the receptor, induce prolonged partial depolarization of the region around muscle end-plate, and inactivation of ...
Emerging Drug Trends 2014
Emerging Drug Trends 2014

... Law enforcement fears that the medication will be diverted and fall into the wrong hands and that drug addicts will crush the capsules and consume the medicine at full strength rather than as it was intended. The effects of hydrocodone are similar to heroin, and Zohydro contains 10 times the amount ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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