Multisource drug product
... Multisource drug product is a drug product that contains the same active drug substance in the same dosage form and is marketed by more than one pharmaceutical manufacturer. Single-source drug products are drug products for which the patent has not yet expired or has certain exclusivities so that on ...
... Multisource drug product is a drug product that contains the same active drug substance in the same dosage form and is marketed by more than one pharmaceutical manufacturer. Single-source drug products are drug products for which the patent has not yet expired or has certain exclusivities so that on ...
Immunosuppressants analysis by means of HPLC
... the transplant of complete organs and after bone-marrow transplants. CsA binds cyclophilin A and FK 506 binds the protein FKB12. In turn, each of the complexes binds to highly conserved domains of the cytosolic protein calcineurin A, and the activity of this serine/threonine phosphatase is thus bloc ...
... the transplant of complete organs and after bone-marrow transplants. CsA binds cyclophilin A and FK 506 binds the protein FKB12. In turn, each of the complexes binds to highly conserved domains of the cytosolic protein calcineurin A, and the activity of this serine/threonine phosphatase is thus bloc ...
PDF file
... Various networks have been used to model cortical processing and learning [27], [28], [29], [30], [31]. Recent cerebral anatomical studies have shown that the architecture of the cerebral cortex appears to have certain general rules. The cortex has the same 6-layer organization scheme across differe ...
... Various networks have been used to model cortical processing and learning [27], [28], [29], [30], [31]. Recent cerebral anatomical studies have shown that the architecture of the cerebral cortex appears to have certain general rules. The cortex has the same 6-layer organization scheme across differe ...
Introduction
... events were documented which were mild and comparable between these the two drugs. Dryness of mouth was the most reported side effect of formoterol inhalation in one study.15 In our study, the greatest number of AEs were reported in the system organ class of central nervous system disorders, with he ...
... events were documented which were mild and comparable between these the two drugs. Dryness of mouth was the most reported side effect of formoterol inhalation in one study.15 In our study, the greatest number of AEs were reported in the system organ class of central nervous system disorders, with he ...
Insomnia - ISpatula
... • lack of evidence to distinguish between zaleplon, zolpidem, zopiclone or shorter acting BDZ hypnotics → drug with the lowest purchase cost should be prescribed. • switching from one of these hypnotics to another should only occur if patient experiences ADEs considered to be directly related to spe ...
... • lack of evidence to distinguish between zaleplon, zolpidem, zopiclone or shorter acting BDZ hypnotics → drug with the lowest purchase cost should be prescribed. • switching from one of these hypnotics to another should only occur if patient experiences ADEs considered to be directly related to spe ...
AVAPRO (irbesartan) tablets
... soon as possible. These adverse outcomes are usually associated with use of these drugs in the second and third trimesters of pregnancy. Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the r ...
... soon as possible. These adverse outcomes are usually associated with use of these drugs in the second and third trimesters of pregnancy. Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the r ...
Lack of Dose Flexibility in Solid Oral Controlled
... instructions would necessitate either a new prescription, or having to swallow multiple doses. Certainly if the dose is decreased, there is but a single option which is obtaining a new prescription. Finding optimal therapeutic blood levels with CR medications is likely a trial and error process for ...
... instructions would necessitate either a new prescription, or having to swallow multiple doses. Certainly if the dose is decreased, there is but a single option which is obtaining a new prescription. Finding optimal therapeutic blood levels with CR medications is likely a trial and error process for ...
Circulatory shock Vasopressors
... induce vasoconstriction and elevate mean arterial pressure few controlled clinical trials have directly compared these or documented improved outcomes adrenergic receptors relevant to vasopressor activity ▪ ά-1 in vascular walls, induces vasoconstriction. Also in the heart and can ↑ the duration of ...
... induce vasoconstriction and elevate mean arterial pressure few controlled clinical trials have directly compared these or documented improved outcomes adrenergic receptors relevant to vasopressor activity ▪ ά-1 in vascular walls, induces vasoconstriction. Also in the heart and can ↑ the duration of ...
Harm Reduction Journal
... inputs and outputs. Coordination requires communication. Cells communicate by thousands of different, but specific, receptors on cell surfaces that respond to thousands of different, but also specific, molecules (ligands) that bind to the receptors. A receptor that is bound to its activating ligand ...
... inputs and outputs. Coordination requires communication. Cells communicate by thousands of different, but specific, receptors on cell surfaces that respond to thousands of different, but also specific, molecules (ligands) that bind to the receptors. A receptor that is bound to its activating ligand ...
anticholinergic drugs and dementia
... medication has been stopped for a number of years. It is possible that anticholinergic use is associated with an increased risk of mild cognitive impairment (MCI). One study has shown that compared with older adults with no exposure to anticholinergic drugs, the odds for having a diagnosis of MCI ma ...
... medication has been stopped for a number of years. It is possible that anticholinergic use is associated with an increased risk of mild cognitive impairment (MCI). One study has shown that compared with older adults with no exposure to anticholinergic drugs, the odds for having a diagnosis of MCI ma ...
pharmaceutical factors
... Thus, on the basis of numerous laboratory researches and experimental information confirmation is got about dependence of medicines on physical and chemical properties of medicinal substances, methods of their obtaining, correlation of active and auxiliary substances in a medicinal form. Biopharmace ...
... Thus, on the basis of numerous laboratory researches and experimental information confirmation is got about dependence of medicines on physical and chemical properties of medicinal substances, methods of their obtaining, correlation of active and auxiliary substances in a medicinal form. Biopharmace ...
Adverse drug reactions: definitions, diagnosis, and management
... unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product.” The term “adverse effect” is preferable t ...
... unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product.” The term “adverse effect” is preferable t ...
Alzheimer's Drugs Market, 2012 - 2017 Brochure
... ability rather than just symptomatic treatments. However, the recent failure of several Alzheimer's drugs in late stage clinical trials present the challenges of developing disease-modifying drugs for areas with an unknown cause. The uncertainty related to the cause of disease, along with unexpected ...
... ability rather than just symptomatic treatments. However, the recent failure of several Alzheimer's drugs in late stage clinical trials present the challenges of developing disease-modifying drugs for areas with an unknown cause. The uncertainty related to the cause of disease, along with unexpected ...
5-meo-dmt.5ht1a.para..
... investigators have suggested that 5-HT1A–mediated events are factors in the behavioral effects of phenethylamine and indoleamine hallucinogens (1,5,19,32,41), this receptor appears to play a modulatory role rather than be directly involved in the stimulus effects of the hallucinogens. With respect t ...
... investigators have suggested that 5-HT1A–mediated events are factors in the behavioral effects of phenethylamine and indoleamine hallucinogens (1,5,19,32,41), this receptor appears to play a modulatory role rather than be directly involved in the stimulus effects of the hallucinogens. With respect t ...
Effects of drugs on periodontal tissue remodeling and clinical
... radiotherapy. It is clearly stated that patients who had been on chemotherapy with busulfan/cyclophosphamide, and who have had less than 2 years of diseasefree life, belong to the high-risk group, as far as orthodontic treatment is concerned. These drugs are known to produce damage to precursor cell ...
... radiotherapy. It is clearly stated that patients who had been on chemotherapy with busulfan/cyclophosphamide, and who have had less than 2 years of diseasefree life, belong to the high-risk group, as far as orthodontic treatment is concerned. These drugs are known to produce damage to precursor cell ...
THE PHYSIOLOGY OF PAIN AND ITS TREATMENT
... nociception. The two primary neurotransmitters are glutamate and substance P. When C fibers are activated during injury they release glutamate, the major excitatory neurotransmitter in the CNS, from their synaptic terminals in the dorsal horn (Basbaum 96). Glutamate has the potential to act on a var ...
... nociception. The two primary neurotransmitters are glutamate and substance P. When C fibers are activated during injury they release glutamate, the major excitatory neurotransmitter in the CNS, from their synaptic terminals in the dorsal horn (Basbaum 96). Glutamate has the potential to act on a var ...
Novel orally bioavailable BRAF inhibitors for the treatment of Opportunity
... cells mutant for RAS (Heidorn et al. Cell 2010;140(2):209–21). Inhibiting CRAF is believed to be beneficial in preventing the onset of squamous cell carcinoma, which is observed as a sideeffect with vemurafenib, the current treatment (Su et al. NEJM ...
... cells mutant for RAS (Heidorn et al. Cell 2010;140(2):209–21). Inhibiting CRAF is believed to be beneficial in preventing the onset of squamous cell carcinoma, which is observed as a sideeffect with vemurafenib, the current treatment (Su et al. NEJM ...
Nebilet (Chronic Heart Failure) - Forecast and Market Analysis to... Brochure
... underserved patient population. In addition, increased use of MRAs over the forecast period in all seven major markets (7MM) will contribute to the increase in the global CHF market size. Nebivolol, which was originally developed by Janssen and is marketed for CHF by Menarini as Nebilet and by Fores ...
... underserved patient population. In addition, increased use of MRAs over the forecast period in all seven major markets (7MM) will contribute to the increase in the global CHF market size. Nebivolol, which was originally developed by Janssen and is marketed for CHF by Menarini as Nebilet and by Fores ...
ASSESSMENT OF THE CABERGOLINE TABLETS Research Article
... compression was selected and Cabergoline tablet formula designed after the properties of excipients had been well studied to be convenient for such low soluble unstable drug in humidity, and using differential scanning calometry (DSC) as a rapid tool to assess the compatibility between them at prefo ...
... compression was selected and Cabergoline tablet formula designed after the properties of excipients had been well studied to be convenient for such low soluble unstable drug in humidity, and using differential scanning calometry (DSC) as a rapid tool to assess the compatibility between them at prefo ...
17.Ramdas T. Dolas, Dr. Avinash Hosmani and Sachin B. Somwanshi
... Nashik, Maharashtra, India-422 102. ...
... Nashik, Maharashtra, India-422 102. ...
Combination Antiretroviral Threapy for HIV Infection
... Factors Contributing to Treatment Failure Why does the combination therapy make sense? Combinations of Antiretroviral Drugs Combinations of Nucleoside analogues (NRTIs) Combinations of NRTIs and non-NRTIs Combinations of Protease Inhibitors and NRTIs and/or NNRTIs ...
... Factors Contributing to Treatment Failure Why does the combination therapy make sense? Combinations of Antiretroviral Drugs Combinations of Nucleoside analogues (NRTIs) Combinations of NRTIs and non-NRTIs Combinations of Protease Inhibitors and NRTIs and/or NNRTIs ...
PHARMACEUTICAL ASPECTS OF NICORANDIL
... in unstable angina; the pain is more frequent, more severe, long lasting, occurs at rest and are not relieved by nitroglycerin under the tongue1. Angina pectoris is the most common form of cardiovascular diseases that require constant monitoring and therapy. Potassium channel openers ...
... in unstable angina; the pain is more frequent, more severe, long lasting, occurs at rest and are not relieved by nitroglycerin under the tongue1. Angina pectoris is the most common form of cardiovascular diseases that require constant monitoring and therapy. Potassium channel openers ...
Predictive Assays for High Throughput Assessment of Cardiac
... throughput screening (HTS) is extremely important for drug development. Human cardiomyocytes derived from stem cell sources can greatly accelerate the development of new chemical entities and improve drug safety by offering more clinically relevant cell-based models than those presently available. S ...
... throughput screening (HTS) is extremely important for drug development. Human cardiomyocytes derived from stem cell sources can greatly accelerate the development of new chemical entities and improve drug safety by offering more clinically relevant cell-based models than those presently available. S ...