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Gastroretentive Drug Delivery Systems As A Potential Tool For
Gastroretentive Drug Delivery Systems As A Potential Tool For

... HPMC K100M) and xanthan gum. Tablets were evaluated for hardness, thickness, friability, and weight variation, drug content, in-vitro buoyancy and drug release. Optimized formulations with HPMC floated with a lag time less than that exhibited by formulations with xanthan gum. The prepared tablets ex ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... Class III drugs prolong the QT interval by blocking mainly the delayed rectifier rapid potassium outward current (IKr), with little effect on depolarization. This K+ channel in encoded by the human ether-a-go-go-related gene (hERG). Inhibition of hERG potassium currents by class III antiarrhythmic d ...
Chapter 4 ppt - s3.amazonaws.com
Chapter 4 ppt - s3.amazonaws.com

... An illegal stimulant derived from the leaves of the coca plant, which is found in South America. Produces intense euphoria, mental alertness, selfconfidence, reduces hunger and raises blood pressure. Cocaine blocks the reuptake of three different neurotransmitters – dopamine, serotonin, and norepine ...
CHAPTER 6 ALCOHOLS
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... alcohol result in a build-up of acetaldehyde because the aldehyde dehydrogenase can only slowly metabolize acetaldehyde . Acetaldehyde is a toxic molecule, contributing to the the nausea and vomiting experienced by those who have over-indulged. There is substantial variation in the levels of these t ...
Complementary Medicine in Allergy and Immunology
Complementary Medicine in Allergy and Immunology

... 1. Acupuncture is a cornerstone of the Traditional Chinese Medicine (TCM) system. It is widely used to treat many chronic illnesses, including asthma, depression, and arthritis. Acupuncture is used by practitioners to restore the balance of “vital flows” by inserting needles at exact points (acupoin ...
drugs for hyperlipidemia
drugs for hyperlipidemia

...  stabilisation of atherosclerotic plaques  increased neovascularisation of ischaemic tissue  enhanced fibrinolysis  immune suppression  osteoclast apoptosis and increased synthetic activity in osteoblasts ...
Comparison of Nitrate Preparations
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SERIES ‘‘RATIONAL USE OF ANTI-TUBERCULOSIS DRUGS’’ Number 3 in this Series
SERIES ‘‘RATIONAL USE OF ANTI-TUBERCULOSIS DRUGS’’ Number 3 in this Series

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Article - The Probation Service
Article - The Probation Service

... failure in Ireland to cope with the heroin epidemic and the emergence of blood-borne diseases in the 1980s, until harm reduction approaches were used. The principle of harm reduction, which appears to influence Irish drug policy increasingly, particularly in urban centres, has provided the philosoph ...
Antipsychotic dosing: found in translation
Antipsychotic dosing: found in translation

... At the same time the imaging work involving dosing was being carried out, an alternative explanation to the 5-HT2/D2 hypothesis was evolving: the fast dissociation model.47 More specifically, studies involving cloned D2 receptors established that antipsychotics come off the D2 receptor at very diffe ...
Press Release - American Epilepsy Society
Press Release - American Epilepsy Society

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Training Curriculum on Drug Addiction Counseling Training Manual
Training Curriculum on Drug Addiction Counseling Training Manual

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Consumer Medication Information: A Reliable Source of Information
Consumer Medication Information: A Reliable Source of Information

drug master file: [18f]fdg
drug master file: [18f]fdg

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Anti-Catabolic Effects Of Anabolic Steroids
Anti-Catabolic Effects Of Anabolic Steroids

... creation of a "psychosomatic state" characterized by sensations of well being, euphoria, increased aggressiveness and tolerance to stress, allowing the athlete to train harder. Such a psychosomatic state would be more beneficial to experienced weight lifters who have developed the motor skills to ex ...
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No Slide Title

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Epithelial cell adhesion molecule-targeted drug delivery for cancer
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EPINEPHRINE - Pfizer Injectables

... Epinephrine should not be administered concomitantly with other sympathomimetic drugs (such as isoproterenol) because of possible additive effects and increased toxicity. Combined effects may induce serious cardiac arrhythmias. They may be administered alternately when the preceding effect of other ...


... secondary to specific TP receptor antagonism, as BAY u 3405 is known to antagonize all three TP receptor subtypes [19], and previous studies have shown that the drug has no significant effect on the airways response to histamine [16]. In vitro studies also confirm no effect against histamine or leuk ...
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Major risk factors (exclusive of LDL cholesterol)

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Teacher`s Manual - Department of Pharmacology, JIPMER
Teacher`s Manual - Department of Pharmacology, JIPMER

... twenty exercises the class is divided into two batches. While one batch is doing an exercise under Section B (Experimental Pharmacology) the other does an exercise under Section C (Clinical Pharmacology). This allows students to gain hands-on training in conducting experiments on animals in small gr ...
Drugs and nutrition Drug disposition in obesity and protein–energy
Drugs and nutrition Drug disposition in obesity and protein–energy

... anatomical volume, but a theoretical body volume that the drug would have to distribute into if the drug concentration everywhere in the body were the same as is found in the blood following the administration of a known dose. In other words, the Vd relates the serum drug concentration to the amount ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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