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Overview of Antimicrobial Agents
Overview of Antimicrobial Agents

... covalently binds to and deactivates many bacterial enzymes-disrupting vital functions ...
Using Psilocybin to Investigate the Relationship between Attention
Using Psilocybin to Investigate the Relationship between Attention

... attempt to gain some insights into the mechanisms involved. Psilocybin, the main hallucinogenic compound found in Psilocybe mushrooms, is the primary focus of this study as it is known to transiently alter an individual’s cognitive and perceptual state (Carter, Pettigrew, Hasler, et al., 2005; Carte ...
low-dose naltrexone (ldn) fact sheet
low-dose naltrexone (ldn) fact sheet

... This information is not intended as medical advice. Responsibility for patient care resides with healthcare professionals on the basis of their professional license, experience and knowledge of a patient. In addition, this information (and any accompanying material) is not intended to replace the at ...
Clozapine - Sussex Partnership NHS Foundation Trust
Clozapine - Sussex Partnership NHS Foundation Trust

... Treatment Breaks If treatment is stopped for more than 48 hours then it is important to restart gradually from 12.5mg once or twice on the first day. Interactions with Clozapine The following are the most common drug interactions. Drug Bone marrow suppressants eg carbamazepine and long acting depot ...
SW_293 5_Benzodiazepines final
SW_293 5_Benzodiazepines final

... Before using this Q&A, read the disclaimer at https://www.sps.nhs.uk/articles/about-ukmi-medicinesqas/ Date prepared: 24th June 2016 ...
geriatric pharmacology
geriatric pharmacology

... people rises with number of medications. ADR’s occur in 4% of those taking 5 drugs; 10% in those taking 6-10 drugs; 28% in those taking 11-15 drugs and 54% in those taking 16 or more drugs. ...
Blexten - aralez pharmaceuticals
Blexten - aralez pharmaceuticals

... of 4.0 ms (90% CI 1.20, 6.73) at 1 h, whereas bilastine 20 mg/day and ketoconazole 400 mg administered concomitantly for four days produced statistically significant QTcF prolongation at all time points from 0.5-12 h, inclusive, on day 4 with a maximum mean difference from placebo of 10.0 ms (90% CI ...
Wellbutrin/Wellbutrin-SR/ Wellbutrin
Wellbutrin/Wellbutrin-SR/ Wellbutrin

... Unlike the selective serotonin reuptake inhibitors (SSRIs) such as Prozac (fluoxetine), Wellbutrin (bupropion) has more than one mechanism of action. Presumably, it works primarily by altering the neurotransmission of dopamine and norepinephrine in the brain. Neurotransmitters, such as dopamine and ...
Determining safe antibiotics for drug hypersensitive patients with the
Determining safe antibiotics for drug hypersensitive patients with the

... which seems to be a hidden cost. Work/school day losses adds to this hidden cost, since most of them are actively working people or students. There is a limited number of allergy clinics in our country, so most of the patients do not have the opportunity to undergo an allergic evaluation in their ho ...
Alternatives to Premarin®
Alternatives to Premarin®

... A medical doctor answers questions about estrogen, menopause, women's health...and horses. What is estrogen? Where is it found? Estrogens are hormones that control the development and function of female sexual characteristics. They also have profound effects on other body tissue and organ systems, i ...
Introduction - African Journals Online
Introduction - African Journals Online

... antibacterials for systemic use to outpatients by pharmacies in Moshi Municipality. Moshi is the capital of Tanzania’s northern Kilimanjaro Region and has a population of 170500 (Moshi Urban Municipality, 2009). The town is host to one of Tanzania’s four university teaching hospitals, a governmental ...
ISSN 2167-910X - International Scientific Indexing
ISSN 2167-910X - International Scientific Indexing

... Clioquinolol (Iodochlorhydroxyquin) was approved as over-thecounter drug in Japan for the treatment of diarrhea and gastric disorders [36]. Drug was marketed in 1953 by Ciba-Geigy [37]. By 1957 to 1970 Japanese people started suffering from SMON (sub acute myelo-optic neuropathy) a complication affe ...
Fact Sheet (2002) Amphetamine and Ecstasy Use in the Caribbean
Fact Sheet (2002) Amphetamine and Ecstasy Use in the Caribbean

... Amphetamines are addictive stimulants that dramatically affect the central nervous system. Amphetamines are a class of drugs, that in chemical terms, are closely related to each other. This family of drugs includes amphetamines sulfate, dexamphetamines and methamphetamine. The principal active ingre ...


... In comparison with the baseline, placebo produced a notable increase in the time estimation after 9 hours of its adm inistration. Similar results have been previously described after administration of be nzodiazepines (Fdez-Guardiola, Jurado and Aguilar-Jiménez, 1984). Thus, it has been demonstrated ...
Drug Monograph
Drug Monograph

... FEV1 rises relatively slowly, reaching a peak after 1 to 3 h.13, 14 The peak response is followed by a plateau of long duration. Doses from 10 to 80 μg showed only slight differences from each other, all being significantly greater than placebo up to 32 h.14 The dip in FEV1 seen between 16 h and 24 ...
VKC and the Allergy Rogues Gallery
VKC and the Allergy Rogues Gallery

... with some studies showing a correlation and others showing none. Patterns of cytokine production are also inconclusive; a recent analysis of patients with VKC demonstrated increases in both the allergy-associated IL-4 and the inflammatory cytokine interferon-γ.3 The picture that emerges is a disease ...
Insomnia - Consumer Reports
Insomnia - Consumer Reports

... nights a week for months on end – should seek out behavioral therapy that improves sleep habits, and use sleeping pills cautiously. If you and your doctor have decided that you need one of the newer pills, we have chosen zolpidem (Ambien) as the Consumer Reports Best Buy Drug, based primarily on the ...
Suppl 1 - ResearchGate
Suppl 1 - ResearchGate

... permanent pathological damage and altered physiological function in certain brain regions. The pathophysiological changes seen in complex partial, simple partial, and absence SE are much less clear. In complex partial SE, intellectual sequelae have been documented (Treiman and Delgado-Escueta, 1983) ...
New Medications for Epilepsy - Turner White Communications
New Medications for Epilepsy - Turner White Communications

... the adverse effects seen with carbamazepine. This can present a confusing clinical picture of increasing carbamazepine toxicity with declining serum levels. Initiating therapy and maintenance dosing. Felbamate should not be used by a patient without a discussion with the prescribing physician about ...
Synthetic marijuana and acute kidney injury: an
Synthetic marijuana and acute kidney injury: an

... a renal biopsy; ATN was the most common histologic finding (six patients), while acute interstitial nephritis was seen in three of the eight patients. Corticosteroids were used in four patients, and five patients required dialysis. No mortality was reported. The pathogenesis of SC-associated AKI remai ...
Introduction of new drugs and drug regimens for the management of
Introduction of new drugs and drug regimens for the management of

... MDR TB is not based on randomised clinical trial evidence but rather on expert opinion. For the treatment of even more resistant TB including XDR TB, the best data available is retrospective cohort data. While there is on-going clinical research into a shorter regimen with the current registered dru ...
OxyContin®: Oxycodone Hydrochloride
OxyContin®: Oxycodone Hydrochloride

... the 13.7 million prescriptions written for opioid analgesic products in 2004 were written for OxyContin2. When used illicitly, OxyContin can be taken in pill form, or crushed and then ingested, snorted, or diluted in water and injected (thereby introducing a range of health concerns related to injec ...
PDF - The Pharma Innovation
PDF - The Pharma Innovation

... Before onset of synthetic era, man was completely dependent on medicinal plants for prevention and treatment of diseases. Medicinal plants, herbs, spices and their remedies are known to ayurveda in India since long times. The value of medicinal plants, herbs and spices as herbal remedies is being lo ...
International Journal for Pharmaceutical Research Scholars (IJPRS)
International Journal for Pharmaceutical Research Scholars (IJPRS)

... doses. Drugs with large single doses frequently are not suitable for extended release because the tablet or capsule needed to maintain a sustained therapeutic blood level of the drug would be too large for the patient to swallow easily. They possess a good margin of safety. The most widely used meas ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... Class III drugs prolong the QT interval by blocking mainly the delayed rectifier rapid potassium outward current (IKr), with little effect on depolarization. This K+ channel in encoded by the human ether-a-go-go-related gene (hERG). Inhibition of hERG potassium currents by class III antiarrhythmic d ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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