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Randomized Comparison Of Antiarrhythmic Drug Therapy With
Randomized Comparison Of Antiarrhythmic Drug Therapy With

... patients with ventricular arrhythmias,5,6 most likely because of proarrhythmic effects.7,8 Since their introduction in 1980,9 numerous reports have shown that implantable cardioverterdefibrillators (ICDs) reduce sudden cardiac death10 –17; more recently, randomized trials have shown that ICDs reduce ...
Document
Document

... of swallowing and hoarse voice, dilated pupils and photophobia and tachycardia. From the anamnesis it is known that the child has eaten some berries with darkviolet colour. Indicate an alkaloid which caused this poisoning A. *Atropine B. Pirenzepine C. Ipratropium bromide D. Plathyphylline E. Methac ...
Prescribing Review
Prescribing Review

... A further meta-analysis of RCTs in 2007 7 considered the efficacy and safety of drugs for chronic insomnia in adults (benzodiazepines – 52 RCTs, Z-drugs – 48 RCTs and antidepressants – 8 RCTs). Sleep onset latency was significantly decreased, but only a small average improvement was achieved. When m ...
Microsoft Word - The AIDS InfoNet
Microsoft Word - The AIDS InfoNet

... a good idea. If the drug doesn’t kill all of the germs, they might change (mutate) so that they can survive even when you are taking medications. When this happens, the drug will stop working. This is called “developing resistance” to the drug. For example, if you are taking TMP/SMX to fight PCP and ...
Toxicologic Pathology
Toxicologic Pathology

... differential marker sets, such molecular components or biochemical pathways will be designated putative liver toxicity predictive biomarkers. Any putative liver toxicity predictive biomarker will represent a new hypothesis that will require testing and validation in subsequent experiments that are c ...
Gentamicin Dosing And Therapeutic Drug Monitoring Guideline
Gentamicin Dosing And Therapeutic Drug Monitoring Guideline

... Gentamicin should be used as a single daily dose regime except for the treatment of bacterial endocarditis. Gentamicin has a potentially toxic side effect profile (nephrotoxicity and ototoxicity. Gentamicin should be used with caution in any patients with an impaired renal function. Due to a reduced ...
Erasmus Partner Universities of Ankara University Faculty of
Erasmus Partner Universities of Ankara University Faculty of

... To dial abroad from Turkey, dial the international code 00 followed by the country code, and then the number including the local area code, but removing the first 0. For example, a London number with an area code of 0207 would be dialed from Turkey as 00 44 207 followed by the number. To dial Turkey ...
Metabolic bone diseases
Metabolic bone diseases

... pamidronate, likely owing to cytokine release. These symptoms are shortlived and generally do not recur with subsequent administration. Zoledronate has been associated with renal toxicity, deterioration of renal function, and potential renal failure. ...
Cyclooxygenase inhibition: between the devil and the deep blue sea
Cyclooxygenase inhibition: between the devil and the deep blue sea

... patients. In the VIGOR study, patients did not use aspirin.19 In patients who had indications for aspirin use but who were enrolled in the trial, there was an increased incidence of myocardial infarction compared to naproxen. Whether this indicates that COX-2 inhibitors promote myocardial infarction ...
Please Highlight this Area and Add your Main Title
Please Highlight this Area and Add your Main Title

...  Prazosin dose dependently attenuated the hyperactive effects of methamphetamine following acute (Day 1) and repeated (Day 4) administrations. The 1.0 mg/kg prazosin dose attenuated the hyperactive effect of methamphetamine without disrupting activity in unpaired control mice. These results are con ...
In-Vivo evaluation of anti-diarrhoeal activity of Ethanolic fruit and
In-Vivo evaluation of anti-diarrhoeal activity of Ethanolic fruit and

... animals each and fasted for 18 hr but water was freely provided. The Group I received Atropine sulphate (0.1mg/kg, i.p.) as standard drug, Group II received saline (5ml/kg, p.o.) as control. While, Group III and IV received orally, EFCC and ERCC (200 and 400mg/kg body weight, respectively). 30 mint ...
3. Results
3. Results

... factors (Gianoulakis & de Waele, 1994; Begleiter et al., 1995; Ferguson & Goldberg, 1997). An estimated 40 to 60% of the individual variation in alcohol preference and vulnerability to alcoholism is genetic in origin, as revealed by adoption studies (Goodwin et al., 1977; Hesselbrock, 1995; Bohman ...
Activity of Argyreia speciosa and Acorus calamus
Activity of Argyreia speciosa and Acorus calamus

... preparation and the paucity of well-controlled studies. This reveals that number of herbal drugs are available for the treatment of various mental disorders but there is a need to explore efficacy of many of them [4]. Acorus calamus (sweet flag) is a tall perennial wetland monocot plant from the Aco ...
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in
First acute haemodynamic study of soluble guanylate cyclase stimulator riociguat in

... has been the lead substance in this group of agents, showing both acute and long-term beneficial effects in patients with PAH [17, 18]. However, phosphodiesterase-5 inhibition is not effective in all patients with PH [19]. The full therapeutic potential of the NO signalling pathway, therefore, remai ...
darbepoetin - Cancer Care Ontario
darbepoetin - Cancer Care Ontario

... hemoglobin. The hemoglobin level should be managed carefully, with a target not to exceed 120  g/L in men or women, and the rate of rise of hemoglobin should not increase by more than 10 g/L  in any 2­week period or 15g/L in any 3­week period.   There is a higher risk of death and serious cardiovasc ...
MODERN TASTE CONCEALING TECHNIQUES IN
MODERN TASTE CONCEALING TECHNIQUES IN

... and the core material in the manufacturing vehicle. Deposition of the liquid polymer coating around the core material occurs if the polymer is absorbed at the interface formed between the core material and the liquid vehicle phase, and this adsorption phenomenon is a prerequisite to the effective co ...
1. Transport of drugs across the inner and outer blood
1. Transport of drugs across the inner and outer blood

... damage as an underlying pathological component. This includes diabetic retinopathy and age-related macular degeneration. Vitamin C, vitamin E, and glutathione are important antioxidants that may have potential in the treatment of retinal diseases caused by oxidative stress. Understanding the transpo ...
ISATX247: a novel calcineurin inhibitor
ISATX247: a novel calcineurin inhibitor

Pyrrosia lingua Reduces Nociception in Mouse
Pyrrosia lingua Reduces Nociception in Mouse

... including chlorogenic acid and astragalin which has been known to possess anti-inflammatory properties.15,16 In the present study, indomethacin, the NSAIDs, produced peripheral analgesic potential followed by significant decrease in writhing response. To confirm the MPL’s anti-nociception on central ...
VICH GL36(R): Studies to evaluate the safety of residues of
VICH GL36(R): Studies to evaluate the safety of residues of

... The intestinal flora plays an important role in maintaining and protecting the health of individuals. This flora provides important functions to the host such as (1) metabolizing endogenous and exogenous compounds and dietary components; (2) producing compounds that are later absorbed; and (3) prote ...
ZOLAMIDE Brand Name: ZOLAMIDE Generic Name: Acetazolamide
ZOLAMIDE Brand Name: ZOLAMIDE Generic Name: Acetazolamide

... Sleep apnea (or sleep apnoea in British English) is a sleep disorder characterized by pauses in breathing during sleep. Each episode, called an apnea lasts long enough so that one or more breaths are missed, and such episodes occur repeatedly throughout sleep. Medications like Acetazolamide lower bl ...
Selective serotonin reuptake inhibitors and risk for gastrointestinal
Selective serotonin reuptake inhibitors and risk for gastrointestinal

... Selective serotonin reuptake inhibitors (SSRIs) are effective drugs partly due to their ability to block the proteins responsible for the transport of serotonin back into the presynaptic neuron. Most of the known effects of SSRIs, beneficial or harmful, are associated with the inhibitory action of t ...
Ofloxacin Otic Solution in Patients With Otitis Media
Ofloxacin Otic Solution in Patients With Otitis Media

... Three study sites, all hospitals in Kagoshima, Japan, enrolled patients. Ethical committee approval of the protocol and the informed consent document was granted at each institution. Eligible were patients of either sex and any age, who were hospitalized or ambulatory, had a diagnosis of chronic sup ...
Hot Flashes - Indiana Pharmacists Alliance
Hot Flashes - Indiana Pharmacists Alliance

... T/F May be associated with bone loss/fracture risk ...
Colesevelam hydrochloride: a bile acid
Colesevelam hydrochloride: a bile acid

... Trial (LRC-CPPT) observed a decrease in cardiovascular events [25] . The reduction in plasma LDL-C levels can be 15–28% at maximal doses of BASs. Patients on BASs who participated in angiographic studies displayed a decrease in progression of coronary artery lesions [26–31] . Despite their benefits, ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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