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Ephedrine and Other Stimulants As Ergogenic Aids
Ephedrine and Other Stimulants As Ergogenic Aids

... heart rate during each stage and at 8 minutes of recovery. Gillies et al. [16] also found that pseudoephedrine at a dose of 120 mg did not produce measurable ergogenic effects during high-intensity exercise of 1 hour duration with cycle ergometry. Bright et al. [17] evaluated heart rate, blood press ...
DETC Template for Rescue College
DETC Template for Rescue College

... Review the websites shown above and discuss your thoughts about what the government needs to do, if anything, to try and regulate drugs more effectively. Post your responses Respond to at least three other learners. ...
38: Opioids
38: Opioids

Methylphenidate vs. amphetamine: Comparative
Methylphenidate vs. amphetamine: Comparative

The effects of chlorpromazine and pimozide in reinforcement
The effects of chlorpromazine and pimozide in reinforcement

... Although the empirical results are clear, Olds and Travis' motivational interpretation is questionable. In agreement, some research appears to show that neuroleptictreated subjects had the motoric capacity to respond but nevertheless did not (e.g., Wise 1982). In contrast, other data seem to show th ...
Antipsychotic Medication
Antipsychotic Medication

... Initial nursing treatment plan should address target symptoms; selection of drug, dose, response, observed side effects and their treatment; patient safety, education, reassurance Nurse-patient relationship forms basis for ongoing therapeutic alliance Nonpharmacological treatment of residual symptom ...
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soung_htn

... negative, EKG wnl. Otherwise healthy.  Which of the following is the most appropriate next step in management? A) Lisinopril B) Chlorthalidone C) Amlodipine D) Hydrochlorothiazide E) Atenolol ...


... In a double-blind, randomized, crossover clinical trial, 10 patients with mild to moderate persistent asthma (who exhibited a fall in forced expiratory volume in one second (FEV1) Š20% following standardized exercise challenge) received 200 mg ABT-761 or matched placebo, orally, 5 h prior to exercis ...
PDF - Hypertension
PDF - Hypertension

The thermodynamic dissociation constants of losartan, paracetamol
The thermodynamic dissociation constants of losartan, paracetamol

... paper, it is assumed that the n × m absorbance data matrix A = ␧C containing the n recorded spectra as rows can be written as the product of the m × p matrix of molar absorptivities ε and the p × n concentration matrix C. Here p is the number of components that absorb in the chosen spectral range. T ...
Discovery Process for Antibody-Based Therapeutics
Discovery Process for Antibody-Based Therapeutics

... viable target for an antibody-based therapeutic project. First, the target molecule should reside in a physiological location accessible to a systemically administered therapeutic antibody. As such, the targeted moiety should be present either on the cell surface (cell surface target), in the extrac ...
Toxic Doses
Toxic Doses

rajiv gandhi university of health sciences, karnataka
rajiv gandhi university of health sciences, karnataka

... In india, it affects about 7 million people. Approximately 40 % of them are women. The prevalence of epilepsy is 0.7 % in India, which is comparable to the U.S. and other developing nations. The estimated incidence rate range from 40 to 60 per 1000,000 population/year. The WHO estimated that approxi ...
choice of sedation for critically ill patients: a rational approach
choice of sedation for critically ill patients: a rational approach

... to ensure effective sedation while minimizing side effects and maintaining a good cost-effectiveness profile. This article discusses the most commonly used sedatives and assesses their usefulness and effectiveness in the clinical setting, citing the latest guidelines provided the Society of Critical ...
A COMPARATIVE STUDY OF THE EFFECT OF ONDANSETRON
A COMPARATIVE STUDY OF THE EFFECT OF ONDANSETRON

... The Elevated plus maze apparatus has two closed arms (50×10×40 cm) and two open arms (50×10 cm) with an open roof, arranged around a central square (10×10 cm). The arms of the same type are opposite to each other. The entire maze is raised 50 cm above the ground. The drugs were administered to the r ...
MORINDA CITRIFOLIA JUICE IN NORMAL RATS   
MORINDA CITRIFOLIA JUICE IN NORMAL RATS   

... medical professionals have shown increased interest in this field as  they recognize the true health benefits of these remedies. “Let food  be your medicine and let medicine be your food” was advised by the  father of medicine, Hippocrates, over two millennia ago. Among the  medicinal  plants  disco ...
Salvia divinorum use and phenomenology: results from an online
Salvia divinorum use and phenomenology: results from an online

... Salvia divinorum is a hallucinogenic plant with ethnopharmacological and recreational uses. It differs from classic serotonergic hallucinogens such as LSD and psilocin in both phenomenology and potent agonist activity of the active component salvinorin A at k-opioid receptors. Awareness of S. divino ...
Digital Edition - Advanstar Communications
Digital Edition - Advanstar Communications

... about unsafe practices in an attempt to prevent future problems. They encourage their staffs to report these situations without fear of retribution. The goal is to correct behaviors rather than punish. These facilities review medication errors and near-misses. They follow strict guidelines to first ...
Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron
Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron

... 3. polyphasic units, large or small. One of the earliest symptoms of ALS may be the onset of distal weakness in the arms or legs, a lower motor neuron sign (Brashear and Elovic, 2011). The leg and foot weakness may manifest itself as weakness of the foot flexors and extensions. Walking may become di ...
What Is The “Safest” Non-Steroidal Anti
What Is The “Safest” Non-Steroidal Anti

... COX-2 inhibitors appear to have similar renal effects as nonselective NSAIDs and do not offer any renal safety benefits over nonselective NSAIDs. A recent large nested case-control study demonstrated a comparable relative risk of acute renal failure among rofecoxib user (RR = 2.31), naproxen user (R ...
Antibacterial Agents which Act Against Cell Metabolism
Antibacterial Agents which Act Against Cell Metabolism

... Selectivity of Trimethoprim • There is a significant differences between the bacterial and the mammalian dihydrofolate reductases away from the active site. • The bacterial enzyme is sensitive to inhibition by trimethoprim by up to 100,000 times lower concentrations than is the mouse enzyme. This d ...
Development of Discriminative Dissolution Media for Marketed
Development of Discriminative Dissolution Media for Marketed

... drug product, the dissolution of the drug under physiological conditions, and the permeability across the gastrointestinal tract determine drug absorption. Based on this, in vitro dissolution may be vital in assessing in vivo performance. Dissolution testing serves as a tool to distinguish between a ...
PPT Notes: Gustation (Taste) & Olfaction
PPT Notes: Gustation (Taste) & Olfaction

... Fox tasted nothing at all. Curious how they could be tasting the chemical differently, they tasted it again. The results were the same. Fox had his friends and family try the chemical then describe how it tasted. Some people tasted nothing. Some found it intensely bitter, and still others thought it ...
10/15/2014 Caffeine is the Most Widely Used Psychoactive Drug Worldwide
10/15/2014 Caffeine is the Most Widely Used Psychoactive Drug Worldwide

... Drugs that prolong half‐life of caffeine (CYP1A2 inhibitors) • Alcohol • Oral contraceptives • Pregnancy hormones • Some SSRIs (Prozac®, Luvox®) ...
Effect of serotonin depletion on cortical spreading depression
Effect of serotonin depletion on cortical spreading depression

... conditions including migraine. It can induce alterations in both neural and vascular compartments. Serotonin (5-HT) depletion is known as a condition involved in migraine pathophysiology. The hyper-excitability of the cortical neurons to the CSD activation in the low 5-HT state has been previously r ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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