Prefrontal Neurons Coding Suppression of Specific Saccades
... tients with frontal lobe damage. Despite the clinical importance of suppression, most studies of the frontal lobe (e.g., Hasegawa et al., 1998, 2000a, 2004) in monkeys have dealt with the generation of movement rather than its suppression. The saccadic system provides an excellent model for the supp ...
... tients with frontal lobe damage. Despite the clinical importance of suppression, most studies of the frontal lobe (e.g., Hasegawa et al., 1998, 2000a, 2004) in monkeys have dealt with the generation of movement rather than its suppression. The saccadic system provides an excellent model for the supp ...
Visual Processing in the Primate Brain
... evolved biological system, the goal of vision is not to produce a veridical description of the external world but a description that facilitates adaptive behavior. Those aspects of the input that contain information critical for behavior will be emphasized and those aspects that carry little informa ...
... evolved biological system, the goal of vision is not to produce a veridical description of the external world but a description that facilitates adaptive behavior. Those aspects of the input that contain information critical for behavior will be emphasized and those aspects that carry little informa ...
Deshpande_Gopikrishna_200708_phd
... unrelenting motivation and drive to reach higher echelons in my life and I wish to express immense gratitude for that. There are no words that can describe my eternal gratitude to my parents, Dr. Narayana Dutt and Katyayini. The person I am today is because of their selfless and committed efforts to ...
... unrelenting motivation and drive to reach higher echelons in my life and I wish to express immense gratitude for that. There are no words that can describe my eternal gratitude to my parents, Dr. Narayana Dutt and Katyayini. The person I am today is because of their selfless and committed efforts to ...
The Neural Foundations of Reaction and Action in Aversive Motivation
... internal factors such as motivation and arousal and performed in order to obtain a goal or reward (Skinner 1938; Estes and Skinner 1941; Estes 1948; Rescorla and LoLordo 1965; Rescorla 1968; Lovibond 1983; Balleine and Dickinson 1998; Holland and Gallagher 2003; Niv et al. 2006). These responses are ...
... internal factors such as motivation and arousal and performed in order to obtain a goal or reward (Skinner 1938; Estes and Skinner 1941; Estes 1948; Rescorla and LoLordo 1965; Rescorla 1968; Lovibond 1983; Balleine and Dickinson 1998; Holland and Gallagher 2003; Niv et al. 2006). These responses are ...
07.11 - UCSD Cognitive Science
... The motor response evoked at each stimulation site was determined by visual inspection and muscle palpation. The threshold current for each response was defined as the stimulus intensity that evoked movement in 50% of the trials. These data were entered into a computer program that ...
... The motor response evoked at each stimulation site was determined by visual inspection and muscle palpation. The threshold current for each response was defined as the stimulus intensity that evoked movement in 50% of the trials. These data were entered into a computer program that ...
REPRESENTATION OF CENTRAL VISUAL FIELDS IN
... about 6-7 m m long and about 1.5 m m in width. The map provided by Talbot and Marshall 16 was used as a reference in making these lesions. Monkey K S 12 had a lesion that was parallel and posterior to the representation of the vertical meridian of the lower visual field on the striate cortex. In the ...
... about 6-7 m m long and about 1.5 m m in width. The map provided by Talbot and Marshall 16 was used as a reference in making these lesions. Monkey K S 12 had a lesion that was parallel and posterior to the representation of the vertical meridian of the lower visual field on the striate cortex. In the ...
Lateral Connectivity and Contextual Interactions in Macaque
... contour integration in primary visual cortex (V1): intrinsic horizontal connections and feedback from higher cortical areas. To distinguish between these, we combined functional mapping with a new technique for labeling axons, a recombinant adenovirus bearing the gene for green fluorescent protein ( ...
... contour integration in primary visual cortex (V1): intrinsic horizontal connections and feedback from higher cortical areas. To distinguish between these, we combined functional mapping with a new technique for labeling axons, a recombinant adenovirus bearing the gene for green fluorescent protein ( ...
Parallel basal ganglia circuits for voluntary and
... everyday behaviours spontaneously (Laplane and Baulac, 1984; Caplan et al., 1990). Patients with Parkinson’s disease may be less motivated in achieving goals and may also show symptoms of depression (Pluck and Brown, 2002). These observations, as well as many others not described here, suggest that ...
... everyday behaviours spontaneously (Laplane and Baulac, 1984; Caplan et al., 1990). Patients with Parkinson’s disease may be less motivated in achieving goals and may also show symptoms of depression (Pluck and Brown, 2002). These observations, as well as many others not described here, suggest that ...
The prefrontal cortex encompasses a large and heterogeneous set of
... type relies on broad structural features shared by more than one architectonic area, including the number and distinction of identifiable layers. In the prefrontal cortex we previously identified several types of cortices, ranging from agranular, which have only three identifiable layers, to eulamin ...
... type relies on broad structural features shared by more than one architectonic area, including the number and distinction of identifiable layers. In the prefrontal cortex we previously identified several types of cortices, ranging from agranular, which have only three identifiable layers, to eulamin ...
Amygdala Modulation of Cerebellar Learning
... amygdala-mediated memory system facilitates the cerebellummediated motor memory system during associative learning (Thompson, 1987; Weisz et al., 1992; Mintz and Wang-Ninio, 2001; Lee and Kim, 2004). The main evidence supporting this theory is that lesions or inactivation of the amygdala slow the ra ...
... amygdala-mediated memory system facilitates the cerebellummediated motor memory system during associative learning (Thompson, 1987; Weisz et al., 1992; Mintz and Wang-Ninio, 2001; Lee and Kim, 2004). The main evidence supporting this theory is that lesions or inactivation of the amygdala slow the ra ...
Mirror neuron functioning: an explanation for
... MNS (mirror neuron system) in human beings, for example with the use of functional magnetic resonance imaging. Iacoboni and colleagues (1999) performed an fMRI on subjects while they were watching someone else move their fingers and while performing finger movements of their own. During this action ...
... MNS (mirror neuron system) in human beings, for example with the use of functional magnetic resonance imaging. Iacoboni and colleagues (1999) performed an fMRI on subjects while they were watching someone else move their fingers and while performing finger movements of their own. During this action ...
chapter 12. schizophrenia 12.4 schizophrenia
... compelling. Other neurotransmitters have also been implicated, including glutamate, serotonin, and γaminobutyric acid (GABA). Neurochemical, structural, and functional imaging abnormalities can be understood in the context of the neural circuits involved and models of the illness. Cortico-striato-th ...
... compelling. Other neurotransmitters have also been implicated, including glutamate, serotonin, and γaminobutyric acid (GABA). Neurochemical, structural, and functional imaging abnormalities can be understood in the context of the neural circuits involved and models of the illness. Cortico-striato-th ...
hoofdstuk 8 - VU-dare
... Until now there have been two studies investigating RSFC in adult psychopaths versus healthy controls, showing atypical connectivity in regions implicated in the DMN and SN (Motzkin et al., 2011; Pujol et al., 2012). However, these studies are not informative with respect to the relation between spe ...
... Until now there have been two studies investigating RSFC in adult psychopaths versus healthy controls, showing atypical connectivity in regions implicated in the DMN and SN (Motzkin et al., 2011; Pujol et al., 2012). However, these studies are not informative with respect to the relation between spe ...
Rethinking Mammalian Brain Evolution1
... remarkable array of new insights into the patterns of brain diversity. Now that tracer techniques have filled this crucial gap in information about basic neural functional anatomy, these data can be integrated with data from physiological and quantitative studies to provide all the pieces of evidenc ...
... remarkable array of new insights into the patterns of brain diversity. Now that tracer techniques have filled this crucial gap in information about basic neural functional anatomy, these data can be integrated with data from physiological and quantitative studies to provide all the pieces of evidenc ...
NIH eRA Commons user name: AM2518 TELEPHONE NUMBER
... GOALS: The aim of this translational research project is to develop a novel treatment for patients with medicationresistant Obsessive Compulsive Disorder (OCD), informed by the neurocircuitry, neurophysiology, and neurochemistry underlying the disorder. Studies provide evidence that, in addition to ...
... GOALS: The aim of this translational research project is to develop a novel treatment for patients with medicationresistant Obsessive Compulsive Disorder (OCD), informed by the neurocircuitry, neurophysiology, and neurochemistry underlying the disorder. Studies provide evidence that, in addition to ...
BMC Neuroscience Serial pathways from primate prefrontal cortex to autonomic areas
... How is information from the cortex transmitted to the periphery? We used two parallel approaches to map simultaneously multiple pathways to determine if hypothalamic autonomic centres are a key link for orbitofrontal areas and medial prefrontal areas, which have been associated with emotional proces ...
... How is information from the cortex transmitted to the periphery? We used two parallel approaches to map simultaneously multiple pathways to determine if hypothalamic autonomic centres are a key link for orbitofrontal areas and medial prefrontal areas, which have been associated with emotional proces ...
Brain Stimulation for Neurological and Psychiatric Disorders
... Anderson did show, however, a reduced burst firing pattern during DBS, which may support the notion that DBS may exert its therapeutic effects via a modulation of basal ganglia firing patterns rather than by changing firing rates. Similar results have also been observed with a rodent model of DBS (C ...
... Anderson did show, however, a reduced burst firing pattern during DBS, which may support the notion that DBS may exert its therapeutic effects via a modulation of basal ganglia firing patterns rather than by changing firing rates. Similar results have also been observed with a rodent model of DBS (C ...
Activity in the Lateral Prefrontal Cortex Reflects Multiple Steps of
... monkeys that performed a path-planning task that required multiple stepwise movements of a cursor within a maze to reach a goal. Figures 1A and 1C show the sequence and timing of events for each trial in our behavioral task. As the monkeys placed their wrists in neutral positions, a start display ap ...
... monkeys that performed a path-planning task that required multiple stepwise movements of a cursor within a maze to reach a goal. Figures 1A and 1C show the sequence and timing of events for each trial in our behavioral task. As the monkeys placed their wrists in neutral positions, a start display ap ...
Organization of Inhibitory Frequency Receptive Fields in Cat Primary
... tions. Characterizing these influences is critical to understanding the relationship between neurophysiology and perception. Frequency tuning curves (FTCs) define a spectral or frequency-intensity RF for auditory neurons. Typically, FTCs of auditory neurons have been defined with single-tone stimuli ...
... tions. Characterizing these influences is critical to understanding the relationship between neurophysiology and perception. Frequency tuning curves (FTCs) define a spectral or frequency-intensity RF for auditory neurons. Typically, FTCs of auditory neurons have been defined with single-tone stimuli ...
PPT
... • In PRR & LIP in the posterior parietal cortex – Maps for the direction of either arm or eye movements that the monkey is intending to perform(SUA) – Direction of planned arm and eye movements(LFP) – Tuning widths for movement directions(LFP, SUA) LFP in general shows responses properties similar t ...
... • In PRR & LIP in the posterior parietal cortex – Maps for the direction of either arm or eye movements that the monkey is intending to perform(SUA) – Direction of planned arm and eye movements(LFP) – Tuning widths for movement directions(LFP, SUA) LFP in general shows responses properties similar t ...
Topical Review
... Background and Purpose—This review will focus on the emerging principles of neural repair after stroke, and on the overlap between cellular mechanisms of neural repair in stroke and clinical principles of recovery and rehabilitation. Summary of Review—Stroke induces axonal sprouting and neurogenesis ...
... Background and Purpose—This review will focus on the emerging principles of neural repair after stroke, and on the overlap between cellular mechanisms of neural repair in stroke and clinical principles of recovery and rehabilitation. Summary of Review—Stroke induces axonal sprouting and neurogenesis ...
A thalamic reticular networking model of consciousness
... given that the thalamus has been referred to as the gateway of nearly all sensory inputs to the corresponding cortical areas. Interestingly, in an early stage of brain development, communicative innervations between the dorsal thalamus and telencephalon must pass through the ventral thalamus, the ma ...
... given that the thalamus has been referred to as the gateway of nearly all sensory inputs to the corresponding cortical areas. Interestingly, in an early stage of brain development, communicative innervations between the dorsal thalamus and telencephalon must pass through the ventral thalamus, the ma ...
Circuits through prefrontal cortex, basal ganglia, and ventral anterior
... c New England Primate Research Center, Harvard Medical School, Boston, MA, USA Accepted 22 March 2004 ...
... c New England Primate Research Center, Harvard Medical School, Boston, MA, USA Accepted 22 March 2004 ...
Contrasting early visual cortical activation states causally involved in
... At the neural level, there is evidence that working memory is mediated by the same neural mechanisms that process the sensory information being retrieved [see the ‘sensory recruitment’ model of working memory (Awh & Jonides, 2001; D’Esposito, 2007; Serences et al., 2009)]. In a very recent functiona ...
... At the neural level, there is evidence that working memory is mediated by the same neural mechanisms that process the sensory information being retrieved [see the ‘sensory recruitment’ model of working memory (Awh & Jonides, 2001; D’Esposito, 2007; Serences et al., 2009)]. In a very recent functiona ...
Motor planning under unpredictable reward: modulations of
... in temporal coordination of goal-directed behavior, consists of a network of neuronal circuits that integrate spatial and timing information for behavioral purpose (Alexander and Crutcher 1990; Hoshi and Tanji, 2000; Staddon 2001; Miller and Phelps, 2010). Previous studies have demonstrated that pre ...
... in temporal coordination of goal-directed behavior, consists of a network of neuronal circuits that integrate spatial and timing information for behavioral purpose (Alexander and Crutcher 1990; Hoshi and Tanji, 2000; Staddon 2001; Miller and Phelps, 2010). Previous studies have demonstrated that pre ...