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... Abnormalities induced by tissue trauma in brain slices are exacerbated by several additional factors. The lack of blood flow in slices dramatically changes the way energy substrates and oxygen are delivered to cells. Energy substrates and O2 are instead supplied exogenously by artificial extracellular ...
... Abnormalities induced by tissue trauma in brain slices are exacerbated by several additional factors. The lack of blood flow in slices dramatically changes the way energy substrates and oxygen are delivered to cells. Energy substrates and O2 are instead supplied exogenously by artificial extracellular ...
STROKE
... Common causes are (from most to least common) atherothrombotic occlusion of large arteries; cerebral embolism (embolic infarction); nonthrombotic occlusion of small, deep cerebral arteries (lacunar infarction); and proximal arterial stenosis with hypotension that decreases cerebral blood flow in ar ...
... Common causes are (from most to least common) atherothrombotic occlusion of large arteries; cerebral embolism (embolic infarction); nonthrombotic occlusion of small, deep cerebral arteries (lacunar infarction); and proximal arterial stenosis with hypotension that decreases cerebral blood flow in ar ...
NIH Public Access
... (AZT) has been delivered using Tf-targeted, PEGylated albumin nanoparticles (PEG-NP). The percentage of drug recovered in the rat brain was 21.1% using the Tf-targeted PEG-NP, while non-targeted PEG-NP alone showed only a 9.3% accumulation after 4 hours (34). However, Tf is likely not an ideal brain ...
... (AZT) has been delivered using Tf-targeted, PEGylated albumin nanoparticles (PEG-NP). The percentage of drug recovered in the rat brain was 21.1% using the Tf-targeted PEG-NP, while non-targeted PEG-NP alone showed only a 9.3% accumulation after 4 hours (34). However, Tf is likely not an ideal brain ...
Neurophysiological investigation of the basis of the fMRI signal
... such potentials, including single-spike responses and ®eld potentials, whereby the latter relate well not only to spike activity but also to subthreshold integrative processes in areas such as dendrites that are otherwise inaccessible. Microelectrode recording methods have been used extensively to o ...
... such potentials, including single-spike responses and ®eld potentials, whereby the latter relate well not only to spike activity but also to subthreshold integrative processes in areas such as dendrites that are otherwise inaccessible. Microelectrode recording methods have been used extensively to o ...
Cell Density in the Border Zone Around Old Small Human Brain
... patient died after a brain stem infarct. The patients were selected among the total number of neuroautopsy cases performed at the Institute of Neuropathology of Rigshospitalet from 1979 to 1984. After immersion fixation in formalin for at least two weeks, the cerebral hemispheres were separated from ...
... patient died after a brain stem infarct. The patients were selected among the total number of neuroautopsy cases performed at the Institute of Neuropathology of Rigshospitalet from 1979 to 1984. After immersion fixation in formalin for at least two weeks, the cerebral hemispheres were separated from ...
Imaging the pathophysiology of major depressive analysis
... Neurochemical imaging of serotonin systems in MDD Interest in serotonin (5-HT) has been central to depression research over the last three decades, owing primarily to reported success of antidepressant pharmacotherapies that selectively target the serotonergic system in both humans and animal models ...
... Neurochemical imaging of serotonin systems in MDD Interest in serotonin (5-HT) has been central to depression research over the last three decades, owing primarily to reported success of antidepressant pharmacotherapies that selectively target the serotonergic system in both humans and animal models ...
Slide 1
... • Role in the pathogenesis of SE was suggested by an outbreak of illness caused by eating mussels contaminated with domoic acid, an analogue of ...
... • Role in the pathogenesis of SE was suggested by an outbreak of illness caused by eating mussels contaminated with domoic acid, an analogue of ...
Glioblastoma - The Brain Tumour Charity
... However, it also helps the tumour cells to repair themselves, making the temozolomide less effective. People with less of the MGMT protein, therefore, respond better to chemotherapy and generally survive longer, as the tumour cells cannot repair themselves so well. You can ask for a ‘biomarker’ tes ...
... However, it also helps the tumour cells to repair themselves, making the temozolomide less effective. People with less of the MGMT protein, therefore, respond better to chemotherapy and generally survive longer, as the tumour cells cannot repair themselves so well. You can ask for a ‘biomarker’ tes ...
workbook - anglické gymnázium brno
... 3. You may not think that caffeine is a drug, but it is. When you drink a soda that contains caffeine, you may feel “jittery.” Why do you think this is? _____________________________ ___________________________________________________________________________ ...
... 3. You may not think that caffeine is a drug, but it is. When you drink a soda that contains caffeine, you may feel “jittery.” Why do you think this is? _____________________________ ___________________________________________________________________________ ...
behavior?
... Neural signals underlie much of the action in our bodies—breathing, moving, using our senses, and so on. Because Jean-Dominique Bauby was still able to send neural signals from his brain to the muscles of his eyelid, he was able to communicate with others. To understand how these neural signals are ...
... Neural signals underlie much of the action in our bodies—breathing, moving, using our senses, and so on. Because Jean-Dominique Bauby was still able to send neural signals from his brain to the muscles of his eyelid, he was able to communicate with others. To understand how these neural signals are ...
Reflex sympathetic dystrophy/complex regional pain syndrome, type 1
... basis of the combination of excessive pain together with autonomic disturbance in the area of the pain. ...
... basis of the combination of excessive pain together with autonomic disturbance in the area of the pain. ...
Sounds of Silence BU scientists are helping a paralyzed man utter his
... throughout the afternoon. While Brumberg returns to Georgia about once a month, he and Guenther conduct most of the experiments from Boston via a video-enabled Skype connection with Kennedy’s lab. Every session follows a similar pattern, with Ramsey improving as the afternoon progresses, lately achi ...
... throughout the afternoon. While Brumberg returns to Georgia about once a month, he and Guenther conduct most of the experiments from Boston via a video-enabled Skype connection with Kennedy’s lab. Every session follows a similar pattern, with Ramsey improving as the afternoon progresses, lately achi ...
brien - Motherisk
... University of Toronto; James F. Brien, basic developmental pharmacology & toxicology, Queen’s University; Gideon Koren, pediatrics and clinical pharmacology & toxicology, Hospital for Sick Children, Toronto; Stephen G. Matthews, developmental neuro-endocrinology, University of Toronto; James N. Reyn ...
... University of Toronto; James F. Brien, basic developmental pharmacology & toxicology, Queen’s University; Gideon Koren, pediatrics and clinical pharmacology & toxicology, Hospital for Sick Children, Toronto; Stephen G. Matthews, developmental neuro-endocrinology, University of Toronto; James N. Reyn ...
Neurotransmitter
... • At electrical synapse, the plasma membranes of preand post-synaptic cells are in close apposition and communication between cells takes place by way of protein channels called GAP JUCTIONS. • Ions can flow from one cell to the other by way of these gap junction to produce an almost equal though so ...
... • At electrical synapse, the plasma membranes of preand post-synaptic cells are in close apposition and communication between cells takes place by way of protein channels called GAP JUCTIONS. • Ions can flow from one cell to the other by way of these gap junction to produce an almost equal though so ...
CONSCIOUSNESS FROM NEURONS 1 Abstract. Consciousness
... right and left striate cortex in Fig. 2). He tentatively proposed that the centrencephalic system might represent the highest level of cerebral activity. There are also suggestions that it functions principally in the control of sensory input (e.g., 2, 3, 7), thus relating it to attentive mechanisms ...
... right and left striate cortex in Fig. 2). He tentatively proposed that the centrencephalic system might represent the highest level of cerebral activity. There are also suggestions that it functions principally in the control of sensory input (e.g., 2, 3, 7), thus relating it to attentive mechanisms ...
analgesia system.
... – depress transmission of pain signals • from the same body area. • Local lateral inhibition in the spinal cord • The simultaneous – physical and – psychogenic excitation of the central analgesia system • the basis of pain relief by ACUPUNCTURE. ...
... – depress transmission of pain signals • from the same body area. • Local lateral inhibition in the spinal cord • The simultaneous – physical and – psychogenic excitation of the central analgesia system • the basis of pain relief by ACUPUNCTURE. ...
BIOLOGICAL FOUNDATIONS OF BEHAVIOR
... Neurons do two important things: They generate electricity, and they release chemicals. Nerve conduction is thus an electrochemical process. The electrical properties of neurons have been known for more than a century, but we have only recently begun to understand the chemical processes involved in ...
... Neurons do two important things: They generate electricity, and they release chemicals. Nerve conduction is thus an electrochemical process. The electrical properties of neurons have been known for more than a century, but we have only recently begun to understand the chemical processes involved in ...
Matching mind to world and vice versa: Functional dissociations
... 4000 ms) to enhance the temporal resolution of the blood oxygenation level-dependent (BOLD) element. We investigated which regions in the brain were engaged during the reading of the scenario (beliefs-scenarios vs. desires-scenarios) as well as during the response phase (beliefsquestion vs. desires- ...
... 4000 ms) to enhance the temporal resolution of the blood oxygenation level-dependent (BOLD) element. We investigated which regions in the brain were engaged during the reading of the scenario (beliefs-scenarios vs. desires-scenarios) as well as during the response phase (beliefsquestion vs. desires- ...
The neural mechanisms of top- down attentional control
... new locus and selectively modulating new stimulus inputs are three stages proposed in current models1,2. Attentional disengagement and voluntary orienting can be considered aspects of top-down attentional control, whereas subsequent selective modulation of sensory inputs reflects the result of this ...
... new locus and selectively modulating new stimulus inputs are three stages proposed in current models1,2. Attentional disengagement and voluntary orienting can be considered aspects of top-down attentional control, whereas subsequent selective modulation of sensory inputs reflects the result of this ...
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... Schwann cell marker reactivity (S-100). Eventually this led to the nomenclature of ‘pseudo-onion bulbs’ when describing whorls of perineurial cells and ‘onion bulbs’ when describing whorls of Schwann cell processes. Intraneural perineurioma can occur in both upper and lower limbs with mostly focal l ...
... Schwann cell marker reactivity (S-100). Eventually this led to the nomenclature of ‘pseudo-onion bulbs’ when describing whorls of perineurial cells and ‘onion bulbs’ when describing whorls of Schwann cell processes. Intraneural perineurioma can occur in both upper and lower limbs with mostly focal l ...
the neurobiology of emotion
... As indicated earlier, certain stimuli are more likely to elicit a fear response than others. However in many cases, a stimulus may acquire properties through learning to elicit a fear response. In addition, we may be "biologically prepared" to associate certain stimuli with emotional responses more ...
... As indicated earlier, certain stimuli are more likely to elicit a fear response than others. However in many cases, a stimulus may acquire properties through learning to elicit a fear response. In addition, we may be "biologically prepared" to associate certain stimuli with emotional responses more ...
Unit 22.1: The Nervous System
... A small child darts in front of your bike as you race down the street. You see the child and immediately react. You put on the brakes, steer away from the child, and yell out a warning—all in just a split second. How do you respond so quickly? Such rapid responses are controlled by your nervous syst ...
... A small child darts in front of your bike as you race down the street. You see the child and immediately react. You put on the brakes, steer away from the child, and yell out a warning—all in just a split second. How do you respond so quickly? Such rapid responses are controlled by your nervous syst ...
a potential late and under recognized consequence of rugby
... traumatic encephalopathy (CTE), is widely recognized. Historically, this was largely considered a phenomenon restricted to boxers, with more recent case series identifying further ‘high risk’ individuals, such as former American footballers, or military personnel. However, in all cases thus far repo ...
... traumatic encephalopathy (CTE), is widely recognized. Historically, this was largely considered a phenomenon restricted to boxers, with more recent case series identifying further ‘high risk’ individuals, such as former American footballers, or military personnel. However, in all cases thus far repo ...
Editorial Translational Neuroimaging of the Mood
... Mood and anxiety disorders include all types of depression, bipolar disorders, and anxiety disorders and are among the top 10 causes of disability worldwide. There is no effective diagnosis or treatment mainly due to our poor understanding of the underlying pathophysiology and particularly the lack ...
... Mood and anxiety disorders include all types of depression, bipolar disorders, and anxiety disorders and are among the top 10 causes of disability worldwide. There is no effective diagnosis or treatment mainly due to our poor understanding of the underlying pathophysiology and particularly the lack ...
Chapter 3 Cognitive Psychology The word `cognition` is derived from
... devices to study cognitive functions. This can help to discover where these processes occur in the brain, and when. In other words, this approach involves using brain imaging and brain anatomy to study ‘live’ cognitive functioning in healthy individuals. As the technology improves, these studies are ...
... devices to study cognitive functions. This can help to discover where these processes occur in the brain, and when. In other words, this approach involves using brain imaging and brain anatomy to study ‘live’ cognitive functioning in healthy individuals. As the technology improves, these studies are ...