Mutations affecting the development of the embryonic zebrafish brain
... role of these loci in the regionalization of the anteroposterior axis of the embryonic brain. In contrast, in the case of NCAM (Cremer et al., 1994; Ono et al., 1994) and follistatin (Matzuk et al., 1995), mutant mouse embryos do not show defects that directly support the postulated roles of these f ...
... role of these loci in the regionalization of the anteroposterior axis of the embryonic brain. In contrast, in the case of NCAM (Cremer et al., 1994; Ono et al., 1994) and follistatin (Matzuk et al., 1995), mutant mouse embryos do not show defects that directly support the postulated roles of these f ...
Materials and Methods
... Learning and memory in mice were assessed using Morris Water Maze test. Wild-type (WT) mice showed a good learning pattern during 4 days of training but AβPP-PS1 mice treated with normal saline could not locate the platform even after 4 days of intense training (figure 1B). Memory tests carried out ...
... Learning and memory in mice were assessed using Morris Water Maze test. Wild-type (WT) mice showed a good learning pattern during 4 days of training but AβPP-PS1 mice treated with normal saline could not locate the platform even after 4 days of intense training (figure 1B). Memory tests carried out ...
Congenital blindness affects diencephalic but not mesencephalic
... and Ptito 2012). Among these structures, the thalamus plays an important part in the sensory processing and integration, given its key position in establishing input– output connections between multiple sensory and motor cortical areas (Cappe et al. 2009). In conditions of early visual deprivation, ...
... and Ptito 2012). Among these structures, the thalamus plays an important part in the sensory processing and integration, given its key position in establishing input– output connections between multiple sensory and motor cortical areas (Cappe et al. 2009). In conditions of early visual deprivation, ...
Three-Dimensional Reconstruction and Stereoscopic Display of
... with a middle section containing many stained profiles and having the largest brain area. This achieves optimal placement of the reconstruction, with respect to field boundaries. The wealth of detail in this initial section facilitates alignment of subsequent sections, especially if the stained prof ...
... with a middle section containing many stained profiles and having the largest brain area. This achieves optimal placement of the reconstruction, with respect to field boundaries. The wealth of detail in this initial section facilitates alignment of subsequent sections, especially if the stained prof ...
Nervous System Chapter 8 ppt copy
... And here’s why: Opiates release 2 to 10 times the amount of dopamine that natural rewards do. What do you do if the volume is too loud? You turn it down, right? Well our brain does that same thing when it adjusts to the overwhelming surges of dopamine (and other neurotransmitters) sent from abusing ...
... And here’s why: Opiates release 2 to 10 times the amount of dopamine that natural rewards do. What do you do if the volume is too loud? You turn it down, right? Well our brain does that same thing when it adjusts to the overwhelming surges of dopamine (and other neurotransmitters) sent from abusing ...
(fMRI) in Brain Tumour Patients
... possible. The gold standard for such assessment is intraoperative ECM, which has in fact been shown to significantly modify long-term survival in low-grade glioma patients [15]. However, intraoperative ECM is invasive, requires experience and expertise of the neurosurgical team, increases surgery du ...
... possible. The gold standard for such assessment is intraoperative ECM, which has in fact been shown to significantly modify long-term survival in low-grade glioma patients [15]. However, intraoperative ECM is invasive, requires experience and expertise of the neurosurgical team, increases surgery du ...
Full Text
... final magnitude of illusions, it also plays a key role in providing an orientation signal for the application of computation by the perceptual system (Figure 2A and 2B). There are other theories that have been formulated based on other perceptual processes to explain some illusions (28, 32-36) for m ...
... final magnitude of illusions, it also plays a key role in providing an orientation signal for the application of computation by the perceptual system (Figure 2A and 2B). There are other theories that have been formulated based on other perceptual processes to explain some illusions (28, 32-36) for m ...
Long-term use of psychedelic drugs is associated with differences in
... for the study. Ayahuasca users were Santo Daime church members who regularly participated in the rituals and were contacted directly by the researchers. Inclusion criteria were: (a) use of ayahuasca at least 50 times in the previous two years; (b) no personal history of psychiatric or neurological d ...
... for the study. Ayahuasca users were Santo Daime church members who regularly participated in the rituals and were contacted directly by the researchers. Inclusion criteria were: (a) use of ayahuasca at least 50 times in the previous two years; (b) no personal history of psychiatric or neurological d ...
Poster
... the Ca+2/CaM complex activates CaMKII, which then phosphorylates other proteins in the cell, like α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. To investigate the role of CaMKII, the Cedarburg SMART (Students Modeling A Research Topic) Team used 3D printing technology to des ...
... the Ca+2/CaM complex activates CaMKII, which then phosphorylates other proteins in the cell, like α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors. To investigate the role of CaMKII, the Cedarburg SMART (Students Modeling A Research Topic) Team used 3D printing technology to des ...
General Organization of Somatosensory System
... effects can sometimes occur during epilepsy or migraine auras. These effects are presumed to arise from abnormal stimulation of the part of the parietal cortex of the brain involved with integrating information from different parts of the body. Stretch receptors are mechanoreceptors responsive to di ...
... effects can sometimes occur during epilepsy or migraine auras. These effects are presumed to arise from abnormal stimulation of the part of the parietal cortex of the brain involved with integrating information from different parts of the body. Stretch receptors are mechanoreceptors responsive to di ...
Astrocyte-Neuron Interactions during Learning May Occur by Lactate
... during different learning protocols and animal models (Gibbs et al., 2006; Newman et al., 2011; Suzuki et al., 2011). These studies showed that memory could be rescued by injection of lactate, although the effect is dependent upon spatiotemporal variables and is partly recapitulated by other compoun ...
... during different learning protocols and animal models (Gibbs et al., 2006; Newman et al., 2011; Suzuki et al., 2011). These studies showed that memory could be rescued by injection of lactate, although the effect is dependent upon spatiotemporal variables and is partly recapitulated by other compoun ...
Bridging Cytoarchitectonics and Connectomics in Human Cerebral
... Von Economo and Koskinas cytoarchitectonic metrics Cytoarchitectonic mappings of the human cortex were taken from the 1925 Von Economo and Koskinas work Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen (Von Economo and Koskinas, 1925) [translated Cytoarchitectonics of the Adult Human Cer ...
... Von Economo and Koskinas cytoarchitectonic metrics Cytoarchitectonic mappings of the human cortex were taken from the 1925 Von Economo and Koskinas work Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen (Von Economo and Koskinas, 1925) [translated Cytoarchitectonics of the Adult Human Cer ...
Human Physiology
... Receives input from sensory neurons Directs activity of motor neurons Association neurons integrate sensory and motor activity Perform learning and memory Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
... Receives input from sensory neurons Directs activity of motor neurons Association neurons integrate sensory and motor activity Perform learning and memory Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. ...
Cytokines, prostaglandins and nitric oxide in the regulation of stress
... of HPA axis signaling and increased corticotrophin-releasing hormone (CRH) secretion from the hypothalamic paraventricular nucleus (PVN) and extra-hypothalamic neurons. During chronic stress-induced inhibition of systemic feedback, cytosolic glucocorticoid receptor (GR) levels were significantly cha ...
... of HPA axis signaling and increased corticotrophin-releasing hormone (CRH) secretion from the hypothalamic paraventricular nucleus (PVN) and extra-hypothalamic neurons. During chronic stress-induced inhibition of systemic feedback, cytosolic glucocorticoid receptor (GR) levels were significantly cha ...
The Discovery of the Reward Pathway
... Addiction is a state in which an organism engages in a compulsive behavior, even when faced with negative consequences. This behavior is reinforcing, or rewarding, as we have just discussed. A major feature of addiction is the loss of control in limiting intake of the addictive substance. The most r ...
... Addiction is a state in which an organism engages in a compulsive behavior, even when faced with negative consequences. This behavior is reinforcing, or rewarding, as we have just discussed. A major feature of addiction is the loss of control in limiting intake of the addictive substance. The most r ...
NeuroQuantology 2015, Volume 13, Issue 3
... noticed that this dimensionless number should necessarily be large in order to make the lifetime of stars sufficient enough to generate heavy chemical elements like carbon. Knowing that carbon is the most essential element for organic material, this is the first assertion called “anthropic coinciden ...
... noticed that this dimensionless number should necessarily be large in order to make the lifetime of stars sufficient enough to generate heavy chemical elements like carbon. Knowing that carbon is the most essential element for organic material, this is the first assertion called “anthropic coinciden ...
Descartes` Error: Emotion, Reason, and the Human Brain
... Its most important achievement is the challenge it poses to cognitive neuroscience. We may well be about to discover that the heart is after all in the head." -Financial Times ...
... Its most important achievement is the challenge it poses to cognitive neuroscience. We may well be about to discover that the heart is after all in the head." -Financial Times ...
Chapter 103: Application Of Imaging Technologies In The
... illustrated with studies done to investigate the levels of DAT blockade achieved by reinforcing doses of cocaine. With PET and appropriate radiotracers, it is possible to measure the levels of DAT occupancy achieved by drugs that block DAT in human subjects reproducibly (8). The levels of DAT occupa ...
... illustrated with studies done to investigate the levels of DAT blockade achieved by reinforcing doses of cocaine. With PET and appropriate radiotracers, it is possible to measure the levels of DAT occupancy achieved by drugs that block DAT in human subjects reproducibly (8). The levels of DAT occupa ...
Sleep imaging and the neuro- psychological assessment of dreams
... memory, language, mental imagery [37]. From this perspective, dream phenomenology can be examined using a neuropsychological approach and the traditional method of clinical-anatomical correlation (see Box 1 for methodological issues in using introspective reports such as dreams). More specifically, ...
... memory, language, mental imagery [37]. From this perspective, dream phenomenology can be examined using a neuropsychological approach and the traditional method of clinical-anatomical correlation (see Box 1 for methodological issues in using introspective reports such as dreams). More specifically, ...
Time Related Effects on Functional Brain Connectivity After
... fashion. Galantamine was hypothesized to mainly affect connectivity with brain structures that are involved in learning and memory mechanisms. Based on our previous study with the SSRI sertraline 75 mg, we expected to see widespread decreases in connectivity immediately after citalopram administrati ...
... fashion. Galantamine was hypothesized to mainly affect connectivity with brain structures that are involved in learning and memory mechanisms. Based on our previous study with the SSRI sertraline 75 mg, we expected to see widespread decreases in connectivity immediately after citalopram administrati ...
Obsessive–Compulsive Symptoms and Related Sex Differences in
... Menzies et al., 2008). These inconsistencies might be due to methodological differences between studies (e.g., differences in sample size, scanning modalities/parameters, and analysis methods), but they may also reflect heterogeneity in the patient groups scanned. For instance, we have shown that br ...
... Menzies et al., 2008). These inconsistencies might be due to methodological differences between studies (e.g., differences in sample size, scanning modalities/parameters, and analysis methods), but they may also reflect heterogeneity in the patient groups scanned. For instance, we have shown that br ...
Chapter 5: Sensation and Perception SW
... information is critical to our survival, there is so much information available at any given time that we would be overwhelmed if we were forced to attend to all of it. In fact, we are aware of only a fraction of the sensory information taken in by our sensory systems at any given time. This chapter ...
... information is critical to our survival, there is so much information available at any given time that we would be overwhelmed if we were forced to attend to all of it. In fact, we are aware of only a fraction of the sensory information taken in by our sensory systems at any given time. This chapter ...
Fixing Functionalism
... This paper will argue that the traditional construal of functionalism is too complex to be a workable scientific theory of consciousness, and introduce an alternative, simpler theory in its place. The argument begins by introducing the notion of a constructor, which is intended to describe just how ...
... This paper will argue that the traditional construal of functionalism is too complex to be a workable scientific theory of consciousness, and introduce an alternative, simpler theory in its place. The argument begins by introducing the notion of a constructor, which is intended to describe just how ...