• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
LabM3bioinformatics
LabM3bioinformatics

...  Bioinformatics can be used to suggest the functions of newly identified genes and proteins. As the proteins with similar functions contain homologus amino acid sequences that corresponds to important functional domains in the three dimensional structure of the proteins, so the function of a protei ...
all of the above - Holy Trinity Diocesan High School
all of the above - Holy Trinity Diocesan High School

... A. small changes in proteins that affect their function or activity in important ways B. changes in regulatory sequences that affect the timing and level of expression of genes C. evolution of a few novel protein-coding genes that play key roles in neural development ...
From Gene to Protein
From Gene to Protein

... What you need to know: ...
The early days of plastid retrograde signaling with
The early days of plastid retrograde signaling with

... section as a possible regulator for coordination of DNA replication between nuclear and organelle genomes) was examined to determine whether it could also regulate nuclear gene expression in Cyanidioschyzon merolae. As is consistent with recent negative reports for this signaling molecule (Mochizuki ...
Gene Section IL22RA1 (interleukin 22 receptor, alpha 1)
Gene Section IL22RA1 (interleukin 22 receptor, alpha 1)

... Oncogenesis Aberrant expression of IL22RA1 in ALK+ALCL lymphoma cells allows these cells to be responsive to IL-22 stimulation, which further stimulate STAT3 signaling and the growth of these cells. Blocking the IL-22 signaling pathway using a neutralizing antibody has been shown to significantly de ...
Chapter 17 Power Point
Chapter 17 Power Point

... nucleus • Both help protect mRNA from degradation by ...
Polymerases pause to help mediate the flow of genetic information
Polymerases pause to help mediate the flow of genetic information

... when one polymerase pauses on the track, it keeps other polymerases from entering the starting gate. Paradoxically, polymerases that pause for longer periods of time can mediate faster and more synchronized gene expression in response to the kinds of signals triggered by various stages of developmen ...
Chapter 18: REGULATION OF GENE EXPRESSION
Chapter 18: REGULATION OF GENE EXPRESSION

... Regulation of Gene Expression in Eukaryotes Regulation of Chromatin Structure: Histone Acetylation a) End view of histone tails protruding outward from a nucleosome. The amino acids in the N-terminal tails are ...
Document
Document

... 12. In prokaryotes, regulatory elements are fixed positions with respect to the gene(s) regulated. How does the situation differ in eukaryotes ? 13. List several mechanisms a cell uses to increase the concentration of a particular mRNA molecule to a very high value. 14. How might a cell be signaled ...
Final Exam Review
Final Exam Review

... 3. Give examples ( from throughout the course) of the four types of chemical reactions seen in biological systems. 4. Describe the structure of the following molecules and where each is found: amylose, amylopectin, glycogen. What are the type of linkages that hold these macromolecules together? 5. L ...
Ensembl Mart
Ensembl Mart

... multiple terms and put them into a table format. • Such as: mouse gene (IDs), chromosome and base pair position • No programming required! ...
Lay summary of the final report Dec 1997
Lay summary of the final report Dec 1997

... and within this sample we have identified 133 mutations and 67 abnormalities needing confirmation, giving a detection rate of approximately 80%. Forty-three of these mutations have been confirmed, and the information released, by the NHS service side of the group. In 31 cases the mutations were used ...
Exam 3 Q3 Review Sheet 3/1/11
Exam 3 Q3 Review Sheet 3/1/11

... 4. Are all genes transcribed and translated all the time in our cells? Explain. 5. When you eat a candy bar, your blood glucose level rises and your pancreas secretes the protein insulin into the blood in response. Insulin binds to insulin receptors on liver cells. A signal transduction cascade is i ...
Greg Thor - gthor eportfolio
Greg Thor - gthor eportfolio

... and Drug Administration and the European Food Safety Agency say that there is no scientific evidence that eating MON810 corn is dangerous. But there is greater disagreement on how genetically modified plants affect ecosystems and whether traditional and genetically modified crops can be kept apart t ...
Cracking the Genetic Code
Cracking the Genetic Code

... However, this finding did not reveal how the “words” in RNA are structured. For example, how long are the words, and are they all the same length? Do they consist of consecutive bases, or ones that are somehow interdigitated? Do words overlap with each other, or are they non-overlapping? Is there so ...
Name ________________________________________ Date __________________ Class Period___________________________________
Name ________________________________________ Date __________________ Class Period___________________________________

... 3. How are the phospholipids molecules in the lipid bilayer of a cell membrane oriented? 4. Why is a cell membrane said to be “selectively permeable”? 5. Why do oxygen molecules pass freely through a cell membrane, while glucose molecules do not? Topic 3: Osmosis 1. What is the process of osmosis? 2 ...
Part I - OCCC.edu
Part I - OCCC.edu

... chromosomes, and then to the altered proteins these genes specify in the organism. Hemoglobin is a prime example; it is the well known protein that carries oxygen in the red blood cell. The hemoglobin protein is made of four polypeptide chains: 2 alpha chains (141 amino acids long and 2 beta chains ...
Strategies of Life
Strategies of Life

... However, DNA does not contain a blueprint for an organism. There isn’t any. And when you hear someone talk about the gene for intelligence, that person is speaking nonsense. Genes don't specify intelligence or beauty or truth or even eye color. In fact genes don't DO anything at all, at least not di ...
AP Biology Ch. 20 - apbiologyclass / FrontPage
AP Biology Ch. 20 - apbiologyclass / FrontPage

... the nucleus of a differentiated cell • Experiments with frog embryos have shown that a transplanted nucleus can often support normal development of the egg • However, the older the donor nucleus, the lower the percentage of normally developing ...
RNAi
RNAi

... Remember the bipartite GAL4-UAS system ...
Modeling biological data and structure with probabilistic networks
Modeling biological data and structure with probabilistic networks

... Slides prepared from text material by Simon Kasif and Arthur Delcher of UIC and Loyola College Computational Methods in Molecular Biology ...
INTERVENING SEQUENCES IN EUKARYOTES
INTERVENING SEQUENCES IN EUKARYOTES

... (b) Splicing of rRNA occurs via self-splicing or “autocatalytic” cleavage. (i) ...
Notes
Notes

... B. Meiosis 1 – diploid = 46 and copies to 23 C. Meiosis 2 - 23 and copies to Haploid 23 D. Crossing over occurs during meiosis 1 in metaphase 1 when homologous chromosomes exchange information Interphase – Prophase – Metaphase – Anaphase – Telophase (Meiosis 1) Prophase – Metaphase – Anaphase – Tele ...
transfer RNA
transfer RNA

... At this point the newly formed RNA is a “PremRNA”, and must be modified before its proteinbuilding instructions can be put to use. A cap binding protein complex (CBC) forms at the 5’ end which is needed when the mRNA is exported from the nucleus. To the 3’ end, a poly-tail of about 100 to 300 nucle ...
Applications_of_Gene_Technology_Student_Notes
Applications_of_Gene_Technology_Student_Notes

... 2. inserting CFTR genes into harmless viruses that are then allowed to ‘infect’ the cells In this method viruses called _____________________ are used These viruses reproduce themselves by injecting their DNA into host cells The viral DNA uses the cell’s enzymes and ribosomes to replicate and produ ...
< 1 ... 199 200 201 202 203 204 205 206 207 ... 320 >

Gene regulatory network



A gene regulatory network or genetic regulatory network (GRN) is a collection of regulators thatinteract with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.The regulator can be DNA, RNA, protein and their complex. The interaction can be direct or indirect (through their transcribed RNA or translated protein).In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.In single-celled organisms, regulatory networks respond to the external environment, optimising the cell at a given time for survival in this environment. Thus a yeast cell, finding itself in a sugar solution, will turn on genes to make enzymes that process the sugar to alcohol. This process, which we associate with wine-making, is how the yeast cell makes its living, gaining energy to multiply, which under normal circumstances would enhance its survival prospects.In multicellular animals the same principle has been put in the service of gene cascades that control body-shape. Each time a cell divides, two cells result which, although they contain the same genome in full, can differ in which genes are turned on and making proteins. Sometimes a 'self-sustaining feedback loop' ensures that a cell maintains its identity and passes it on. Less understood is the mechanism of epigenetics by which chromatin modification may provide cellular memory by blocking or allowing transcription. A major feature of multicellular animals is the use of morphogen gradients, which in effect provide a positioning system that tells a cell where in the body it is, and hence what sort of cell to become. A gene that is turned on in one cell may make a product that leaves the cell and diffuses through adjacent cells, entering them and turning on genes only when it is present above a certain threshold level. These cells are thus induced into a new fate, and may even generate other morphogens that signal back to the original cell. Over longer distances morphogens may use the active process of signal transduction. Such signalling controls embryogenesis, the building of a body plan from scratch through a series of sequential steps. They also control and maintain adult bodies through feedback processes, and the loss of such feedback because of a mutation can be responsible for the cell proliferation that is seen in cancer. In parallel with this process of building structure, the gene cascade turns on genes that make structural proteins that give each cell the physical properties it needs.It has been suggested that, because biological molecular interactions are intrinsically stochastic, gene networks are the result of cellular processes and not their cause (i.e. cellular Darwinism). However, recent experimental evidence has favored the attractor view of cell fates.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report