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ISC105 General Biology I
ISC105 General Biology I

... 16.4 Translation is the RNA-directed synthesis of a polypeptide: a closer look 16.5 Mutations of one or a few nucleotides can affect protein structure and function 17. Regulation of Gene Expression 17.1 Bacteria often respond to environmental change by regulating transcription 17.2 Eukaryotic gene e ...
PDF file of the lecture on "Gene Transfer"
PDF file of the lecture on "Gene Transfer"

... •  Gene  transfer  by  uptake  of  naked/soluble  DNA   fragments  from  the  surrounding  environment   and  the  expression  of  the  encoded  geneAc   informaAon  in  the  recipient  cell.   •  It  works  best  with  DNA  from  closely ...
Genom
Genom

... If the genetic or epi-genetic information is changed, it can lead to cancer transformation (mutation in somatic cell) or to transmiting of genetic disease ( mutation in germ cell) ...
Slide 1
Slide 1

... Start site. A start site for transcription. A promoter. A region a few hundred nucleotides 'upstream' of the gene (toward the 5' end). It is not transcribed into mRNA, but plays a role in controlling the transcription of the gene. Transcription factors bind to specific nucleotide sequences in the pr ...
Timeline for Biology Microbiology and Genetics
Timeline for Biology Microbiology and Genetics

... 1952 - Rosalind Franklin concludes that DNA is a double helix 1953 - After examining Franklin's unpublished data, James D. Watson and Francis Crick publish a double-helix structure for DNA. 1955 - Marianne Grunberg-Manago and Severo Ochoa discover the first nucleicacid-synthesizing enzyme (polynucle ...
Make your own monster
Make your own monster

... the prolonged administration of silver nitrate for dubious medicinal purposes. Most variation in human form, however, occurs because the genes responsible for every part of our internal and external make-up come in different versions. Each of these ...
HIV Worksheet A Lead-in 1 Do you know what the letters
HIV Worksheet A Lead-in 1 Do you know what the letters

... Step 2 - The viral RNA and core proteins are released into the cytoplasm where reverse transcriptase converts the viral RNA to DNA. Step 3 - Viral DNA, now doublestranded is transported into the nucleus and the nuclear membrane. In the nucleus, the enzyme called integrase fuses it with the host cell ...
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... • These mice are glowing because scientists inserted a gene found in certain bioluminescent jellyfish into their DNA. That gene is a recipe for a protein that glows green when hit by blue or ultraviolet light. The protein is present throughout their bodies. As a result, their skin, eyes and organs ...
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... systems-level view of tissue regeneration models to advance knowledge of regenerative biology and stem cell self-renewal. Scientists can use RegenDB to analyze integrated functional genomic datasets of regenerative processes to identify conserved gene networks within and across species. RegenDB repr ...
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... converted to allolactose (inducer)binds repressor and changes its conformation repressor can not bind operator Adenylyl cyclase is actively – in the glucose absencesynthesising cAMP cAMP-CAP complex binds CAP site RNA polymerase initiates transcription at promoter site polycistronic mRNA(3 sets ...
Facts for Consumers - Physicians and Scientists for Global
Facts for Consumers - Physicians and Scientists for Global

... species to another, usually between closely related species. This is known as horizontal gene transfer. HGT between species from different kingdoms is extremely rare in nature, even on an evolutionary timescale. Genetic engineering has now become the main cause of HGT in the biosphere. Novel genes i ...
Questions to lecture 15. Cancer
Questions to lecture 15. Cancer

... 3. One of the key kinase which is activated in response to DNA damage is: A. B. C. D. ...
Lytic and Lysogenic Pathways • Once inside its host cell, a virus can
Lytic and Lysogenic Pathways • Once inside its host cell, a virus can

... of the latent period and the eclipse period • Inside the host, the viral DNA/RNA replicates itself • Using resources from the cell, new full-fledged viruses form o The formation of the first full virus ends the eclipse period • Ultimately, the bacterium will become over-packed with bacteriophages o ...
Problems of Cell Cycle 1. If the most basic function of the cell cycle is
Problems of Cell Cycle 1. If the most basic function of the cell cycle is

... you suppose the length of S phase increases with increasing DNA content in different species, but remains constant with increasing DNA content in the same species? ...
Chapter 16 Gene Regulation Levels of Gene Regulation Bacterial
Chapter 16 Gene Regulation Levels of Gene Regulation Bacterial

... – DNA regulatory elements which are bound by transcriptional activator proteins. • Example: Metallothionein – Response elements to heavy metals • Eukaryotic Genes may be activated by several different response elements ...
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lecture-1-viruses-an-introduction

... Martha Chase, and published in 1952, used phage T2 and E. coli to provide strong evidence that genes are composed of DNA. • The first enhancers to be characterized were in genes of simian virus 40 (SV40). • The first transcription factor to be characterized was the transplantation (T) antigen of SV4 ...
Powerpoint - rlsmart.net
Powerpoint - rlsmart.net

... found at the same locus) -Example: Everyone has the gene for eye color. The possible alleles are blue, brown, green, etc. ...
Viruses - Humble ISD
Viruses - Humble ISD

... Benefits of Viruses - Not all viruses are bad! – __________________ for viral diseases are made from _________________________ of the virus – A weaker virus is capable of stimulating an ______________________ and creating _________________, but not causing illness Viral Hosts ...
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... Alternative strategies for sequencing an entire genome. Celera used the maps and sequence data from the public consortium ...
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presentation source

... eukaryotes, which do. Prokaryotes fall into two major groups: Eubacteria and Archaea. Phenotypically, eubacteria and archaea are very similar to each other. However, it has been demonstrated by using molecular data that archaea are more closely related to eukaryotes than to eubacteria, and thus it a ...
The genome sequence is a jazz score
The genome sequence is a jazz score

... Metaphors and jazz and genetics: three words of caution Firstly: there are many ways to understand the nature, attributes and functions of metaphors; I here use just one. A renewed discussion on the uses of metaphors in ‘public health genomics’ could be of interest.14,15 Secondly: no single metaphor ...
A Gene Coexpression Network for Global Discovery of Conserved
A Gene Coexpression Network for Global Discovery of Conserved

... other model organisms would be useful to expand the multi-species network? ► Would the multi-species network be as useful for species that are more closely related? ► Gene orthology is based on protein sequence similarity. Does sequence conservation equate to conserved function? ► Are 12 clusters of ...
Gene Regulation
Gene Regulation

... 1. Adding the poly adenine tail  site of addition of the adenine tail can influence the function of the protein. 2. mRNA splicing  site of intron removal can make an active or inactive mRNA. 3. Differences in splicing of the exons can result in different transcripts. Example: variation in polypept ...
Chap5 Genetic Engineering
Chap5 Genetic Engineering

... Plasmid vectors can replicate with ori, an ori from one yeast strain can normally function in different yeast hosts, albeit not always with the same degree of efficiency. Up to 200 copies can be present in a single cell via additional selection. ...
Unit 2 Concepts Study Guide
Unit 2 Concepts Study Guide

... Lesson 2: Our Genetic Future Concepts: 1. Gene therapy is a type of disease treatment in which faulty genes are replaced by functional copies. 2. Various vectors, including viruses, can be used to transfer DNA into human cells. o Adenovirus: infects diving and non-diving cells, can cause immune res ...
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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