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R N A & PROTEIN SYNTHESIS
R N A & PROTEIN SYNTHESIS

... The function of normal human red blood cells, which are disk-shaped, is to transport oxygen from the lungs to the other organs of the body. Each red blood cell contains millions of molecules of hemoglobin that carries the ...
Class Outline 1. Understanding polynucleotide structure (Read) 2
Class Outline 1. Understanding polynucleotide structure (Read) 2

... the sequence of the amino acids within proteins. The code is read by copying stretches of DNA into the related nucleic acid RNA in a process called transcription. Within cells, DNA is organized into long structures called chromosomes. During cell division these chromosomes are duplicated in the proc ...
Case study: PacBio and Dovetail - For cashew genome, combining
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... “There are lots of published plant genomes that are not very good quality because they were done exclusively with short-read sequencing, so there are lots of 'holes' in these Swiss-cheese-like genomes.” The scientists had previously worked with Single Molecule, Real-Time (SMRT®) Sequencing from PacB ...
6/30/14 1 The only goal a virus has is to… General characteristics of
6/30/14 1 The only goal a virus has is to… General characteristics of

... §  Are inert when not within a host cell §  Require a living host to multiply §  obligate intracellular parasites §  Multiply within living cells by using the host cell’s enzymes, nucleic acids, amino acids etc ...
Proteogenomics - The Fenyo Lab
Proteogenomics - The Fenyo Lab

... • The Proteogenomic Mapping Tool: Java-based search of peptides against 6-reading frame sequence database (Sanders WS, et al). ...
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here

... This course will provide background knowledge of five basic units of Biochemistry and the relationship between genes and proteins within the cell. Unit 1 deals with the molecules of life, DNA, RNA, nucleotides and the central dogma of molecular biology. Unit 2 covers the decoding of the genetic code ...
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No Slide Title

... lac regulatory region Activator binding site ...
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Powerpoint Slides 5.2

... 6) Naked RNA can be used to infect spheroplasts whose cell walls have been removed by enzyme treatments. This demonstrates that the viral RNA has all the information needed to infect cells. The host range can be expanded greatly by using this treatment to circumvent the pili. 7) Plasmids expressing ...
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... back up. If using e.g., YFP-DHFR tagging vector, you should expect to see YFP positive parasite emerging after pass 3 or 4. In some cases the population may become homogeneously positive over time, but in other cases a mixed population may result necessitating screening of several clones. We have se ...
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PDF

... [6-9]. No protein gene sequence information has been available from any plant-pathogenic MLO, and thus their codon usage was unknown. In order to obtain comparable data for the MLOs, we cloned and sequenced a segment of an operon containing several ribosomal protein genes. Since ribosomal protein ge ...
Key Concepts
Key Concepts

...  Conjugation is mediated by the F plasmid, which is the classic example of an episome—an element that may exist as a free circular plasmid, or that may become integrated into the bacterial chromosome as a linear sequence. The F plasmid is a large circular DNA ~100 kb in length.  In its free (plasm ...
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Principles of BIOCHEMISTRY

... Bacterial genomics research is important in: • Combating bacterial resistance to antibiotics ...
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lecture - Haloarchaea

... Perhaps due to deamination of exposed C’s in the leading strand, producing C>T mutations. Theory only. ...
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... b) What would be a potential consequence if RNA could freely diffuse out of the nucleus? (4 points) Unprocessed RNAs could potentially be translated. This would result in the production of unusual proteins as introns may still be present in some of the RNAs, and code for additional amino acids or ab ...
a short review of biology I
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Acuity Change in Fellow Eye
Acuity Change in Fellow Eye

... diseases and conditions that in majority have a genetic basis ...
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... the active site (which is made up of R groups with specific chemistry, i.e. hydrophobic). Enzyme rate is affected by:  pH (optimal for each enzyme),  temperature (optimal for each enzyme but in general increased temp means increased collisions so rate goes up initially; too much heat can denature ...
The National Eye Institute Supercourse
The National Eye Institute Supercourse

... diseases and conditions that in majority have a genetic basis ...
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... • Scientists can diagnose many human genetic disorders by using PCR and primers corresponding to cloned disease genes, then sequencing the amplified product to look for the disease-causing mutation • Even when a disease gene has not been cloned, presence of an abnormal allele can be diagnosed if a c ...
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PASS Leader Info

... 3) Possible changes to the amino acid where it occurs as well as to all downstream amino acids from that point. 4) Poor replication of the DNA. 5) Immediate death to the cell. ...
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology

... putative CoA-synthtase subunit, and an aryl-CoA thioesterase, respectively) was observed during growth of Hfx. D1227 on BA, PPA and CA, but not on 3HBA. This suggests that these genes encode steps in a CoA-mediated benzoate pathway, as PPA, CA and BA are metabolised by a convergent route (Fu and Ori ...
Effect of Novobiocin and Other DNA Gyrase lnhibitors on Virus
Effect of Novobiocin and Other DNA Gyrase lnhibitors on Virus

... 'nov-resistant' synthesis in uninfected cells corresponds closely to that seen for cellular D N A in infected cells in the presence or absence of nov. For all four antibiotics tested, the concentration required to inhibit HSV-1 replication in infected cells is several orders of magnitude higher than ...
MOLECULAR GENETICS You Are Here* Genes --
MOLECULAR GENETICS You Are Here* Genes --

... a primary RNA transcript is processed by splicing to assemble protein coding exons Presence of Introns: Absent in prokaryotes: they have few non-coding DNA sequences as eukaryotic complexity grows so does non-coding DNA [figure] ...
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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