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... 03-131 Genes, Drugs, and Disease ...
Viewpoint - Prof Ralf Metzler
Viewpoint - Prof Ralf Metzler

... tion of intermittent one- and three-dimensional diffusion gives rise to a search strategy that is much more efficient than each of its contributing individual mechanisms. As sketched in Fig. 1, apart from one- and three-dimensional diffusion a transcription factor can also jump between two DNA segme ...
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Protein Synthesis

... • DNA contains genes, sequences of nucleotide bases • These genes code for polypeptides (proteins) • Proteins are used to build cells and do much of the work inside cells ...
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Null hypotheses in evolutionary biology

... The neutral theory of molecular evolution Motoo Kimura (1968) High levels of polymorphism (variation) in protein and DNA sequences among individuals and species are difficult to reconcile with mutation-selection equilibrium (Ch 5.4) Most mutations affecting fitness are deleterious, hence quickly eli ...
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Molecular Evolution - Integrative Biology

... The first estimate of time to the most recent common ancestor of humans and chimps was obtained using molecular data (~ 5-6 Myr); new hominid fossil discoveries since then are in agreement with the molecular data. The molecular clock is not constant; different lineages can show faster, or slower rat ...
Bioinformatics
Bioinformatics

... DNA • The deoxyribonucleic acid (DNA) is a nucleic acid that contains the genetic information necessary to the biosynthesis of RNA and protein (essential molecules for the development and proper functioning of most living organisms). • From a chemical standpoint, DNA is an organic polymer consistin ...
Ch 25 and 26 Phylogeny and The History of Life on Earth
Ch 25 and 26 Phylogeny and The History of Life on Earth

... • Morphological- comparing body forms of current and extinct organisms • Molecular- comparing DNA; the closer the sequence the more related – Some analogous structures (wings in insect compared to a bat) may have very different molecular origins. The result of convergent evolution. ...
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... Completion On the lines provided, complete the following sentences. 1. In _______________________ , only animals with desired characteristics are allowed to produce the next generation. 2. Crossing dissimilar individuals to bring together the best of both Organisms is called ________________________ ...
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... One of these color indicators is the chemical 5-bromo-4-chloro3-indolyl-β-D- galactoside. Fortunately, the chemical is usually referred to by its common name, X-gal. X-gal is colorless, but when it is cleaved by beta-galactosidase, one of the products is dark blue. Therefore, if you grow bacteria th ...
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... of Protein Synthesis Streptomycin: inhibits initiation and causes misreading of the genetic code Tetracyclines: inhibit binding of aa-tRNA Chloramphenicol: inhibits peptide bond formation ...
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Protein Synthesis - Issaquah Connect

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... – Polypeptides form proteins that cells and organisms use Describe the process of translation. Include the following: • mRNA termination • tRNA start codon • Ribosome P site • Amino acid A site • Initiation stop codon • Elongation Modification Mutations can change the meaning of genes • Mutations ar ...
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Protein Synthesis

... Click on the picture to watch a video of the process. Look though all the pictures and write down any questions you have for lecture. ...
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7.012 Practice Quiz 2 2004

... a) i) Where would this receptor protein be localized if the cell was lacking SRP? The receptor protein would be found in the cytosol. It would be non-functional. ii) Where would this receptor protein be localized if its signaling domain were deleted? It would be inserted into the plasma membrane, bu ...
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Essential knowledge 2.E.1: Timing and coordination of specific

... Genetic regulation by microRNAs plays an important role in the development of organisms and the control of cellular functions. • MicroRNAs - post-transcriptional regulators; • They are short RNAs, about 22 nucleotides long; bind to the mRNAs, usually silencing them. • Wow that is short! Must be why ...
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... 41. DNA _________________just the section that codes the directions for the needed protein. RNA nucleotides come in and bind with the DNA nitrogen Bases So, transcription is 42. __________________ the mRNA code from a strand of DNA Occurs in the nucleus so the message can be sent from 43. DNA to the ...
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overview rna, transcription, translation

... During translation, a small ribosomal subunit attaches to a mRNA molecule. At the same time, an initiator tRNA molecule recognizes and binds to a specific codon sequence on the same mRNA molecule. A large ribosomal subunit then joins the newly formed complex. The initiator tRNA resides in one bindin ...
12-3 RNA and Protein Synthesis
12-3 RNA and Protein Synthesis

... produce proteins. The cell uses all three main forms of RNA during this process.  messenger RNA  ribosomal RNA  transfer RNA ...
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