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Structure-Function of the Glucagon Receptor Family of G Protein
Structure-Function of the Glucagon Receptor Family of G Protein

... sharing 44% sequence identity with the glucagon receptor (Usdin et al. 1993). The GIPR exhibits highly specific GIP binding, although some binding by exendin-4, a GLP-1R agonist, was noted at very high concentrations of 1–10 µM (Gremlich et al. 1995). However, there was no demonstrable response of t ...
The autonomic nervous system
The autonomic nervous system

... It’s primary process is to stimulate the body's fight-or-flight response. And it constantly active at a basic level to maintain homeostasis. Fight-or-flight response means that when somebody is in danger under the command of the hypothalamus the neural activity and the hormones together unleash the ...
File - Wk 1-2
File - Wk 1-2

... 3. Describe autonomic neurotransmitter control of the heart, gut and bladder, including thermoregulation and food intake. Neurotransmitter – along with electrical signals, are the language of the nervous system. Allows communication between neurons. In the ANS there are 2 types of neurotransmitters: ...
Neurons and Nervous Systems
Neurons and Nervous Systems

... There are many types of neurotransmitters, and each may have multiple receptor subtypes. For example, ACh has two: • Nicotinic receptors are ionotropic and mainly excitatory • Muscarinic receptors are metabotropic and mainly inhibitory The action of a neurotransmitter depends on the receptor to whic ...
Module 4 SG - HallquistCPHS.com
Module 4 SG - HallquistCPHS.com

... a. how you learn to express emotions. b. how to help people overcome emotional disorders. c. life-span changes in the expression of emotion. d. the chemical changes that accompany emotions. 24. You are able to pull your hand quickly away from hot water before pain is felt because: a. movement of the ...
Neurotransmission in the rat amygdala related to fear and anxiety
Neurotransmission in the rat amygdala related to fear and anxiety

... inhibitory avoidance, Izquierdo and colieagues:J'> found that immediate posttraining infusion of APV into either the amygdala, medial septum, or hippocampus, blocked memory measured 18 h after training. lJ-2-Amino-5-phosphonovalerate caused amnesia when infused into either the hippocampus or amygdal ...
Peripheral and Central Mechanisms of Pain Generation
Peripheral and Central Mechanisms of Pain Generation

... evoke stronger responses than in the non-sensitized state. After sensitization of “pain fibres”, normally non-painful stimuli can cause pain. Cutaneous nociceptors are in particular sensitized to thermal stimuli; nociceptors in deep somatic tissue such as joint and muscle show pronounced sensitizatio ...
"Touch". In: Encyclopedia of Life Sciences (ELS)
"Touch". In: Encyclopedia of Life Sciences (ELS)

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Alcohol Withdrawal Syndrome - American College of Medical
Alcohol Withdrawal Syndrome - American College of Medical

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36_LectureSlidesAdde..

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A22254 Touch [version 2.0 ].
A22254 Touch [version 2.0 ].

... Biophysics of sensory transduction by mechanoreceptors Indentation or lateral stretch of the skin is believed to excite mechanoreceptors by direct gating of cation channels in the sensory nerve ending. Mechanical stimulation deforms the receptor protein, thus opening stretch-sensitive ion channels, ...
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Role of Astrocytes, Soluble Factors, Cells Adhesion Molecules and

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A Negative Feedback Mechanism Between Brain Catecholamines

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Drugs and Toxins
Drugs and Toxins

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Chapter 11 PowerPoint - Hillsborough Community College
Chapter 11 PowerPoint - Hillsborough Community College

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1 Introduction to Nerve Cells and Nervous Systems
1 Introduction to Nerve Cells and Nervous Systems

... the cell membrane and, usually, changes in membrane potential that increase or decrease the cell’s excitability. Over a longer time course one neuron may release substances on to another that affect that cell’s metabolism and be responsible for altering synaptic efficacy and maintaining synaptic lin ...
Brain Waves Volunteer Instructor Guide
Brain Waves Volunteer Instructor Guide

... Adaptation is experienced when a stimulus is present for a long time. After being in a freshly painted room for a while, the smell may not be as strong. However, someone entering the room for the first time will find the smell very strong because they are not adapted. ...
Sensory Afferent Neurotransmission in Caudal Nucleus Tractus
Sensory Afferent Neurotransmission in Caudal Nucleus Tractus

... The nucleus of the solitary tract (NTS) receives a wide range of sensory inputs including gustatory, gastrointestinal and cardiorespiratory which are loosely segregated viscerotopically to subnuclei. Our laboratory has focused on a dorsomedial area of caudal NTS (mNTS) which is critical for cardiova ...
Chapter 12 - Mesa Community College
Chapter 12 - Mesa Community College

... Guillain-Barre Syndrome – demyelination of axons in the PNS by macrophages macrophages destroy Schwann cells which can regenerate person suffers from acute paralysis but most patients recover completely Oligodendrocytes have "octopus-like extensions" that wrap several different axons and therefore d ...
Chapter 13: Peripheral Nervous System
Chapter 13: Peripheral Nervous System

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15. ANS (Stick Figure) Anat Lecture
15. ANS (Stick Figure) Anat Lecture

... (efferent) neurons; one neuron from the CNS to a ganglion (called the preganglionic neuron) and the second neuron from the ganglion to the effector tissue (called the postganglionic neuron). It has 2 divisions: Parasympathetic and Sympathetic. There are 3 basic effector tissues in the ANS:  cardiac ...
Chapter 11: Fundamentals of the Nervous System and Nervous Tissue
Chapter 11: Fundamentals of the Nervous System and Nervous Tissue

... Guillain-Barre Syndrome – demyelination of axons in the PNS by macrophages macrophages destroy Schwann cells which can regenerate person suffers from acute paralysis but most patients recover completely Oligodendrocytes have "octopus-like extensions" that wrap several different axons and therefore d ...
Ch 27 Neurones and Neural Pathways
Ch 27 Neurones and Neural Pathways

... between an axon ending of one neurone and the membrane of the dendrite (or sometimes the cell body) of the next neurone • The nerve cell before the synapse is called the presynaptic neurone; the one after is called the postsynaptic neurone • It is at the synapse that information is passed on by mean ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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