lactuca sativa linn. - Journal of Pharmaceutical and Scientific
... Plant origin drugs have played a vital role in the prevention and treatment of diseases in Unani medicine and it becomes popular day by day due to its low cost and less adverse effect. One such drug is Tukhme kahu (Seeds) belong to the family Asteraceae is an important herbal drugs which have hypogl ...
... Plant origin drugs have played a vital role in the prevention and treatment of diseases in Unani medicine and it becomes popular day by day due to its low cost and less adverse effect. One such drug is Tukhme kahu (Seeds) belong to the family Asteraceae is an important herbal drugs which have hypogl ...
A study with cumulative doses of formoterol and salbutamol in
... In adults a cumulative dose response study has shown that formoterol by the inhaled route was 5-15 times more potent than salbutamol with respect to bronchodilatation [2]. After cumulative doses of 39 and 123 Jlg of formoterol, approximately 90 and 95%, respectively, of the bronchodilating capacity ...
... In adults a cumulative dose response study has shown that formoterol by the inhaled route was 5-15 times more potent than salbutamol with respect to bronchodilatation [2]. After cumulative doses of 39 and 123 Jlg of formoterol, approximately 90 and 95%, respectively, of the bronchodilating capacity ...
Treating Chronic Pain
... NMDA receptor mechanisms are involved in the development of hyperalgesia/sensitization (as are opioid metabolites) NMDA receptor is also involved with opioid ...
... NMDA receptor mechanisms are involved in the development of hyperalgesia/sensitization (as are opioid metabolites) NMDA receptor is also involved with opioid ...
The New High: Designer Drugs and New Trends
... similar effects to LSD. There is little known about the pharmacological characteristics of B-Fly, but evidence that it has vasoconstrictive properties in humans. B-Fly is known to be a serotonin agonist, or that binds to the serotonin cell and triggers a response. ...
... similar effects to LSD. There is little known about the pharmacological characteristics of B-Fly, but evidence that it has vasoconstrictive properties in humans. B-Fly is known to be a serotonin agonist, or that binds to the serotonin cell and triggers a response. ...
CUSTOM CARBON-14 RADIOLABELLING
... produce reactive fragments. The secondary effect is from the -radiation that may produce ions and radicals, which can react with other molecules or interact with solvent if present. Knowledge of radiolysis is empirical and cannot be predicted with confidence prior to synthesis of the compound. Howe ...
... produce reactive fragments. The secondary effect is from the -radiation that may produce ions and radicals, which can react with other molecules or interact with solvent if present. Knowledge of radiolysis is empirical and cannot be predicted with confidence prior to synthesis of the compound. Howe ...
Cannabis
... • Effects can generally be felt within 15 minutes and peak effects occur within 30 to 60 minutes post-smoking and last 2-4 hours • Spectrum of effects precludes classification as a stimulant, sedative or hallucinogen. ...
... • Effects can generally be felt within 15 minutes and peak effects occur within 30 to 60 minutes post-smoking and last 2-4 hours • Spectrum of effects precludes classification as a stimulant, sedative or hallucinogen. ...
Martindale: The Complete Drug Reference
... ), and is believed to be more active than levothyroxine ( ...
... ), and is believed to be more active than levothyroxine ( ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... certain subsets of alcoholism. Lithium has been used in many medical disorders, especially cluster headache and dermatological disorders (seborrheic dermatitis, eczematoid dermatitis, and genital herpes). [4]Initially, lithium was used to treat Urinary calculi and gout with little success [5], till ...
... certain subsets of alcoholism. Lithium has been used in many medical disorders, especially cluster headache and dermatological disorders (seborrheic dermatitis, eczematoid dermatitis, and genital herpes). [4]Initially, lithium was used to treat Urinary calculi and gout with little success [5], till ...
Clearing the Smoke on Cannabis: Cannabis Use and Driving – An
... on divided attention tasks — those tasks that require the ability to monitor and respond to more than one source of information at a time. Cannabis also compromised the ability to handle unexpected events, such as a pedestrian darting out on the roadway. Combining cannabis with even small amounts of ...
... on divided attention tasks — those tasks that require the ability to monitor and respond to more than one source of information at a time. Cannabis also compromised the ability to handle unexpected events, such as a pedestrian darting out on the roadway. Combining cannabis with even small amounts of ...
(BE) Study Reports
... annual reports. The FDA has recently published proposed rules1 which take into account the CIOMS Working Group II proposals2. − In the EU, Council Directive 93/39/EEC and Council Regulation 2309/93 require reports with a periodicity of 6 months for two years, annually for the three following years a ...
... annual reports. The FDA has recently published proposed rules1 which take into account the CIOMS Working Group II proposals2. − In the EU, Council Directive 93/39/EEC and Council Regulation 2309/93 require reports with a periodicity of 6 months for two years, annually for the three following years a ...
The Dopamine Transporter and Cocaine Medication Development
... of self-administration sessions. It is critical to study several doses of the treatment medication to determine an effective dose range and a maximally effective dose that lacks overt behavioral toxicity. The effects of the treatment medication typically are evaluated first in combination with a dos ...
... of self-administration sessions. It is critical to study several doses of the treatment medication to determine an effective dose range and a maximally effective dose that lacks overt behavioral toxicity. The effects of the treatment medication typically are evaluated first in combination with a dos ...
opioid toxicity - CEU Professor On-line
... The abuse of opium and opium-derived products is a very old one (Note: through the text, the word opioid will be used. This word indicates that the drug is a synthetically or semisynthetically derived derived opium product. Opiates are drugs that are derived directly from the opium poppy, eg, morphi ...
... The abuse of opium and opium-derived products is a very old one (Note: through the text, the word opioid will be used. This word indicates that the drug is a synthetically or semisynthetically derived derived opium product. Opiates are drugs that are derived directly from the opium poppy, eg, morphi ...
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... The World Health Organization (WHO) statistics indicate a yearly occurrence of 110 million clinical cases of malaria, within the order of 270 million people being infected and 1-2 million dying from the disease (Krogstad et.al, 1992 ; Schapira et.al, 1993). More than 80% of the world's malaria casua ...
... The World Health Organization (WHO) statistics indicate a yearly occurrence of 110 million clinical cases of malaria, within the order of 270 million people being infected and 1-2 million dying from the disease (Krogstad et.al, 1992 ; Schapira et.al, 1993). More than 80% of the world's malaria casua ...
xtram plus
... than the parent drug. The plasma concentrations of M1 are several-fold lower than those of tramadol and the contribution to the clinical effect are unlikely to change on multiple dosing. Paracetamol is principally metabolized in the liver through two major hepatic routes: glucuronidation and sulpha ...
... than the parent drug. The plasma concentrations of M1 are several-fold lower than those of tramadol and the contribution to the clinical effect are unlikely to change on multiple dosing. Paracetamol is principally metabolized in the liver through two major hepatic routes: glucuronidation and sulpha ...
mAb-1 Mono
... v Drug: Drug interactions (small molecules)- competing pathways involved in clearance mechanisms v Combination of large and small molecule considerations Ø Small molecules (<500D) vs large molecules (>5-150kD) Ø Half life differences: hours vs 4-5 weeks (for typical mAbs) Ø Impact on biomark ...
... v Drug: Drug interactions (small molecules)- competing pathways involved in clearance mechanisms v Combination of large and small molecule considerations Ø Small molecules (<500D) vs large molecules (>5-150kD) Ø Half life differences: hours vs 4-5 weeks (for typical mAbs) Ø Impact on biomark ...
Evaluation of Diuretic activity of aqueous and alcoholic rhizomes
... International Journal of Research in Ayurveda & Pharmacy, 1(2), Nov-Dec 2010 648-652 ...
... International Journal of Research in Ayurveda & Pharmacy, 1(2), Nov-Dec 2010 648-652 ...
Naturopathy Act, 2007 - O. Reg. 168/15
... of subsection (1) and who, in doing so, mixes, prepares, packages or labels two or more substances specified in Table 1 for the purpose of administering a customized therapeutic product to a patient by inhalation must comply with all the standards of practice set out in subsection 11 (2), with any n ...
... of subsection (1) and who, in doing so, mixes, prepares, packages or labels two or more substances specified in Table 1 for the purpose of administering a customized therapeutic product to a patient by inhalation must comply with all the standards of practice set out in subsection 11 (2), with any n ...
Guar gum/borax hydrogel - eXPRESS Polymer Letters
... are prepared. In particular, GG and SCLG show important different characteristics: (a) GG dissolves in water as a random coil while SCLG exhibits a triple helix conformation in aqueous solution with a persistence length of about 200 nm [10, 25]; (b) borax promotes a rapid gelation of GG [26] by mean ...
... are prepared. In particular, GG and SCLG show important different characteristics: (a) GG dissolves in water as a random coil while SCLG exhibits a triple helix conformation in aqueous solution with a persistence length of about 200 nm [10, 25]; (b) borax promotes a rapid gelation of GG [26] by mean ...
Naturopathy Act, 2007 - O. Reg. 168/15
... of subsection (1) and who, in doing so, mixes, prepares, packages or labels two or more substances specified in Table 1 for the purpose of administering a customized therapeutic product to a patient by inhalation must comply with all the standards of practice set out in subsection 11 (2), with any n ...
... of subsection (1) and who, in doing so, mixes, prepares, packages or labels two or more substances specified in Table 1 for the purpose of administering a customized therapeutic product to a patient by inhalation must comply with all the standards of practice set out in subsection 11 (2), with any n ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... blood pressure did not vary significantly between the two drug groups. However, mean respiratory rate and oxygen saturation differed significantly between the two drug groups at 5, 10, and 30 minutes after drug administration9Fisgin et al. also detected tachypnea in their study children after admini ...
... blood pressure did not vary significantly between the two drug groups. However, mean respiratory rate and oxygen saturation differed significantly between the two drug groups at 5, 10, and 30 minutes after drug administration9Fisgin et al. also detected tachypnea in their study children after admini ...
meth_presentation
... Intravenous is the fastest route of drug administration, causing blood concentrations to rise the most quickly. The onset of the rush induced by injection can occur in as little as a few seconds. Injection is also the route with the greatest health risk. ...
... Intravenous is the fastest route of drug administration, causing blood concentrations to rise the most quickly. The onset of the rush induced by injection can occur in as little as a few seconds. Injection is also the route with the greatest health risk. ...
a review of the adverse side effects associated with antipsychotics
... medication may be markedly impaired if its side effect profile affects its acceptability to patients. This review explores the evidence for widely reported subcategories of side effects of both typical and atypical antipsychotics. Guidance from the National Institute for Clinical Excellence (NICE) i ...
... medication may be markedly impaired if its side effect profile affects its acceptability to patients. This review explores the evidence for widely reported subcategories of side effects of both typical and atypical antipsychotics. Guidance from the National Institute for Clinical Excellence (NICE) i ...
Mephedrone: use, subjective effects and health risks
... The indication that mephedrone has a dependence liability is also a matter of concern. Around 30% of our participants experienced three or more DSM‐IV dependence criteria. The predominant symptoms were increased tolerance (the study did not ask about within session develo ...
... The indication that mephedrone has a dependence liability is also a matter of concern. Around 30% of our participants experienced three or more DSM‐IV dependence criteria. The predominant symptoms were increased tolerance (the study did not ask about within session develo ...
Untitled
... It is our great pleasure to welcome you here in Helsinki at GPEN 2014. About one year of organizing and planning lies behind us and finally the 10th biennial meeting of the Globalization of Pharmaceutics Education Network (GPEN) has arrived. It has been both a demanding and rewarding time and we are ...
... It is our great pleasure to welcome you here in Helsinki at GPEN 2014. About one year of organizing and planning lies behind us and finally the 10th biennial meeting of the Globalization of Pharmaceutics Education Network (GPEN) has arrived. It has been both a demanding and rewarding time and we are ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.