Vomiting
... changes, including PR and QT prolongation and QRS widening, that are believed to be caused by sodium channel blockage by dolasetron metabolites. Diarrhea, headache, dizziness, and musculoskeletal pain have been reported as well. These medications can be expensive. ...
... changes, including PR and QT prolongation and QRS widening, that are believed to be caused by sodium channel blockage by dolasetron metabolites. Diarrhea, headache, dizziness, and musculoskeletal pain have been reported as well. These medications can be expensive. ...
The PBAC agenda primarily consists of applications relating to the
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
PDF version of March 2015 PBAC Meeting Agenda
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
cardiopulmonary, biochemical, and haematological changes after
... blood flow, which in turn might have caused a rise in BUN (9). In addition, increased hepatic urea production from amino acid degradation could account for the observed increase in BUN values as was recorded by Eichner et al. (5). Similar changes in BUN were also reported after administration of det ...
... blood flow, which in turn might have caused a rise in BUN (9). In addition, increased hepatic urea production from amino acid degradation could account for the observed increase in BUN values as was recorded by Eichner et al. (5). Similar changes in BUN were also reported after administration of det ...
PHARMACEUTICAL BENEFITS ADVISORY COMMITTEE (PBAC
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
... circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be listed in alphabetical order by drug name. There is no provision for consumer comments to the PBAC on agenda item 8 which relates to pricing matters. Pharmaceu ...
Preview the material
... movements associated with PLMD may occur several times per night or in clusters. The disorder more commonly occurs among people who are excessively tired and who do not normally get enough quality sleep. In fact, it is worsened by lack of sleep, even though the condition often further produces ineff ...
... movements associated with PLMD may occur several times per night or in clusters. The disorder more commonly occurs among people who are excessively tired and who do not normally get enough quality sleep. In fact, it is worsened by lack of sleep, even though the condition often further produces ineff ...
PMMA-stimulus generalization to the optical isomers of MBDB and 3
... insured by continuation of the training sessions on a daily basis (except on a generalization test day; see below). On one of the two days before a generalization test, approximately half of the animals would receive the training dose of the training drug and the remainder would receive saline; afte ...
... insured by continuation of the training sessions on a daily basis (except on a generalization test day; see below). On one of the two days before a generalization test, approximately half of the animals would receive the training dose of the training drug and the remainder would receive saline; afte ...
Leaning on syrup The misuse of opioid cough
... Diphenhydramine is one of the oldest antihistamines. It is known as Benadryl, or by its generic name, diphenhydramine hydrochloride. Typical adult doses range between 75 to 300 mg. per day. In syrup form, it relieves coughs (e.g., Benylin syrup) and it is also an ingredient in creams and ointments u ...
... Diphenhydramine is one of the oldest antihistamines. It is known as Benadryl, or by its generic name, diphenhydramine hydrochloride. Typical adult doses range between 75 to 300 mg. per day. In syrup form, it relieves coughs (e.g., Benylin syrup) and it is also an ingredient in creams and ointments u ...
Preservation of post-transplant lung function with aerosol cyclosporin
... dose quantification have previously been described [5, 7]. To summarise, a known quantity of radioactive tag (Technetium 99m bound to diethylenetriaminepentaacetic acid) was mixed into the study medication (drug or placebo) prior to nebulisation. The volume of study medication deposited within the l ...
... dose quantification have previously been described [5, 7]. To summarise, a known quantity of radioactive tag (Technetium 99m bound to diethylenetriaminepentaacetic acid) was mixed into the study medication (drug or placebo) prior to nebulisation. The volume of study medication deposited within the l ...
Antifungals and their use in veterinary ophthalmology - GEAC-UFV
... Polyene macrolide antibiotics, the first major group of antifungal agents to be discovered [35], are a group of structurally similar products of Streptomyces spp. Since the discovery of nystatin (previously known as fungicidin) in 1950 [36], more than 60 members of the class have been described [35]; ...
... Polyene macrolide antibiotics, the first major group of antifungal agents to be discovered [35], are a group of structurally similar products of Streptomyces spp. Since the discovery of nystatin (previously known as fungicidin) in 1950 [36], more than 60 members of the class have been described [35]; ...
HIGHLIGHTS OF PRESCRIBING INFORMATION These
... (TAF). The recommended dosage of ODEFSEY is one tablet taken orally once daily with a meal in the following patient population: adults and in pediatric patients 12 years of age and older with body weight greater than or equal to 35 kg and a creatinine clearance greater than or equal to 30 mL per min ...
... (TAF). The recommended dosage of ODEFSEY is one tablet taken orally once daily with a meal in the following patient population: adults and in pediatric patients 12 years of age and older with body weight greater than or equal to 35 kg and a creatinine clearance greater than or equal to 30 mL per min ...
Outline - leader
... 2. How do the characteristics of the study population compare to those who are frail? By virtue of the strong association between multimorbidity and frailty, frail older adults are almost always excluded from large-scale clinical trials, which generates uncertainty about the applicability of trial ...
... 2. How do the characteristics of the study population compare to those who are frail? By virtue of the strong association between multimorbidity and frailty, frail older adults are almost always excluded from large-scale clinical trials, which generates uncertainty about the applicability of trial ...
Protease inhibitor plasma concentrations in HIV antiretroviral therapy
... the PIs are subjected to varying degrees of first-pass metabolism, especially saquinavir, due to varying affinity to the drug-metabolising enzyme system cytochrome P450 and the drug-transporting protein P-glycoprotein in both the small intestine and in the liver [56-59]. First pass metabolism can be ...
... the PIs are subjected to varying degrees of first-pass metabolism, especially saquinavir, due to varying affinity to the drug-metabolising enzyme system cytochrome P450 and the drug-transporting protein P-glycoprotein in both the small intestine and in the liver [56-59]. First pass metabolism can be ...
Amphetamine-Type Stimulants: A Global Review, 1996
... are closer to the technical competence of other international agencies, the problems they pose will be highlighted, for the sake of consistency, in appropriate chapters of Parts one and two. The >ecstasy= group of substances are covered in this review because they are chemically related to the amphe ...
... are closer to the technical competence of other international agencies, the problems they pose will be highlighted, for the sake of consistency, in appropriate chapters of Parts one and two. The >ecstasy= group of substances are covered in this review because they are chemically related to the amphe ...
PRODUCT MONOGRAPH Frisium® (clobazam) Tablets, 10 MG
... Drug Interactions: Concomitant administration of drugs that inhibit the cytochrome P-450 enzyme system may enhance and prolong the action of clobazam. Most studies of the potential interactions of clobazam with other antiepileptic agents have failed to demonstrate significant interactions with pheny ...
... Drug Interactions: Concomitant administration of drugs that inhibit the cytochrome P-450 enzyme system may enhance and prolong the action of clobazam. Most studies of the potential interactions of clobazam with other antiepileptic agents have failed to demonstrate significant interactions with pheny ...
Vancomycin Assay - Beckman Coulter
... are within their control limits, calibration is verified. If any control is not within its control limits, rerun that control. If the result is then within the control limits, calibration is verified. If the control is not within the control limits after repeat testing, recalibrate according to the ...
... are within their control limits, calibration is verified. If any control is not within its control limits, rerun that control. If the result is then within the control limits, calibration is verified. If the control is not within the control limits after repeat testing, recalibrate according to the ...
The effect of anticholinergic drugs on the
... mucoid cells of the neck of the glands, the cardiac glands, and the pyloric glands, whereas it had no effect on the activity of the surface epithelial cells. Our observations on the effect of hypoglycaemic stimulation on mucus secretion agree with those of Grossberg et al. (1950), namely, that the i ...
... mucoid cells of the neck of the glands, the cardiac glands, and the pyloric glands, whereas it had no effect on the activity of the surface epithelial cells. Our observations on the effect of hypoglycaemic stimulation on mucus secretion agree with those of Grossberg et al. (1950), namely, that the i ...
Guidelines
... statistical analysis. However, subjects in a crossover trial who do not provide evaluable data for both of the test and reference products (or who fail to provide evaluable data for the single period in a parallel group trial) should not be included. The analysis for each comparison should be co ...
... statistical analysis. However, subjects in a crossover trial who do not provide evaluable data for both of the test and reference products (or who fail to provide evaluable data for the single period in a parallel group trial) should not be included. The analysis for each comparison should be co ...
etoposide injection usp
... Although some minor differences in pharmacokinetic parameters between elderly and nonelderly patients have been observed, these differences were not considered clinically significant. Etoposide and its metabolites are known to be substantially excreted by the kidney, and the risk of adverse reactions ...
... Although some minor differences in pharmacokinetic parameters between elderly and nonelderly patients have been observed, these differences were not considered clinically significant. Etoposide and its metabolites are known to be substantially excreted by the kidney, and the risk of adverse reactions ...
BDJ 2000. Persistent impairment of taste with terbinafine
... stopped immediately. Recovery was partial with continued difficulty tasting sugar or salt in food some 3 years later. In comparison our patient described partial loss of sweetness with a persistent bitter taste, followed by a partial recovery over an 18month period. The taste disturbance associated ...
... stopped immediately. Recovery was partial with continued difficulty tasting sugar or salt in food some 3 years later. In comparison our patient described partial loss of sweetness with a persistent bitter taste, followed by a partial recovery over an 18month period. The taste disturbance associated ...
幻灯片 1 - 漳州片仔癀药业股份有限公司
... enjoyed high notability and a good reputation through the effect of its public praise. Many old overseas Chinese regard Pien Tze Huang as a "miraculous drug". When approaching their end, the dying must take Pien Tze Huang, or they will die with everlasting regret. If they are not satisfied with thei ...
... enjoyed high notability and a good reputation through the effect of its public praise. Many old overseas Chinese regard Pien Tze Huang as a "miraculous drug". When approaching their end, the dying must take Pien Tze Huang, or they will die with everlasting regret. If they are not satisfied with thei ...
Studies on Variability in Olanzapine Disposition
... important limitations of this drug therapy. Olanzapine (OLA) is a second-generation antipsychotic (SGA) drug widely used in the treatment of schizophrenia and schizoaffective disorder. The drug has well-documented effects against positive symptoms and has been claimed to be efficacious also against ...
... important limitations of this drug therapy. Olanzapine (OLA) is a second-generation antipsychotic (SGA) drug widely used in the treatment of schizophrenia and schizoaffective disorder. The drug has well-documented effects against positive symptoms and has been claimed to be efficacious also against ...
Stimulant and Cocaine Psychosis
... detrimental to health Potential toxicity increases with larger doses Acute cocaine poisoning leads to profound CNS stimulation which can lead to respiratory or cardiac arrest Whether a drug produces a toxic effect, depends on the dose Illicit cocaine is often adulterated and the adulterants ...
... detrimental to health Potential toxicity increases with larger doses Acute cocaine poisoning leads to profound CNS stimulation which can lead to respiratory or cardiac arrest Whether a drug produces a toxic effect, depends on the dose Illicit cocaine is often adulterated and the adulterants ...
Preview the test
... The process of making new neurons is called neuroception neurogenesis neuronascency neuronativity ...
... The process of making new neurons is called neuroception neurogenesis neuronascency neuronativity ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.