PRONIOSOMAL GEL AS A CARRIER FOR TRANSDERMAL DRUG DELIVERY OF... Research Article ASTHA MISHRA*, ANUPRIYA KAPOOR, SHILPI BHARGAVA
... associated with severe side effects in the g.i.t. Transdermal drug delivery has been recognized as an alternative route to oral delivery. Proniosomal gel offers a versatile delivery concept with the potential for drug delivery via the transdermal route. In this study different proniosomal gel bases ...
... associated with severe side effects in the g.i.t. Transdermal drug delivery has been recognized as an alternative route to oral delivery. Proniosomal gel offers a versatile delivery concept with the potential for drug delivery via the transdermal route. In this study different proniosomal gel bases ...
REFERENCES
... safety of linezolid. However, we have three main comments. First of all, although the best way to provide high-quality data on the possible efficacy of a drug (or a combination of drugs) in TB treatment is to perform a randomised clinical trial (RCT), this is particularly complicated to organise in ...
... safety of linezolid. However, we have three main comments. First of all, although the best way to provide high-quality data on the possible efficacy of a drug (or a combination of drugs) in TB treatment is to perform a randomised clinical trial (RCT), this is particularly complicated to organise in ...
... ruary 2009, is already making a difference in clinical practice. It has been the experience of rheumatologists that patients who have had trouble with allopurinol often respond to febuxostat. The first dose can quickly drop the serum urate level down to 5 mg/dL or so, without side effects or rash. I ...
Infectious Diseases of the Dog and Cat, 3rd Edition
... combination with aminoglycosides to treat mixed infections associated with bowel perforation and intraabdominal sepsis (see Chapter 89). In people the drug effectively treats intraabdominal, pelvic, pleuropulmonary, CNS, and bone and joint infections. Side effects of metronidazole include gastrointe ...
... combination with aminoglycosides to treat mixed infections associated with bowel perforation and intraabdominal sepsis (see Chapter 89). In people the drug effectively treats intraabdominal, pelvic, pleuropulmonary, CNS, and bone and joint infections. Side effects of metronidazole include gastrointe ...
Prescribing Pattern of Drugs in the Geriatric Patients in
... collaboration with prescribers which will be very effective in preventing the adverse drug reactions that may be resulting from inappropriate medications in geriatric patients. ...
... collaboration with prescribers which will be very effective in preventing the adverse drug reactions that may be resulting from inappropriate medications in geriatric patients. ...
Screening for an antibiotic
... • Antibiotics are categorized as bactericidal if they kill the susceptible bacteria or bacteriostatic if they reversibly inhibit the growth of bacteria. • In general the use of bactericidal antibiotics is preferred but many factors may dictate the use of a bacteriostatic antibiotic. • When a bacteri ...
... • Antibiotics are categorized as bactericidal if they kill the susceptible bacteria or bacteriostatic if they reversibly inhibit the growth of bacteria. • In general the use of bactericidal antibiotics is preferred but many factors may dictate the use of a bacteriostatic antibiotic. • When a bacteri ...
All the different ways to look at TRAMADOL DEATHS
... DRUG RELATED DEATHS UNARQ: directly or indirectly caused by the intake of illicit drugs and psychotropic substances ...
... DRUG RELATED DEATHS UNARQ: directly or indirectly caused by the intake of illicit drugs and psychotropic substances ...
Pharmacology and Pharmacokinetics of Alcohol and Opioids
... z The rate of metabolism is Zero order – i.e. it is not ...
... z The rate of metabolism is Zero order – i.e. it is not ...
Drug Metabolising Enzymes
... The conversion from one chemical form of a substance to another. The term metabolism is commonly used probably because products of drug transformation are called metabolites. Metabolism is an essential pharmacokinetic process, which renders lipid soluble and non-polar compounds to water solubl ...
... The conversion from one chemical form of a substance to another. The term metabolism is commonly used probably because products of drug transformation are called metabolites. Metabolism is an essential pharmacokinetic process, which renders lipid soluble and non-polar compounds to water solubl ...
“THERE ARE MANY WAYS OF PRACTICING THE HEALING ART
... medication in his practice shows that he does not understand the delicate machinery of the human organism. He is introducing into the system a seed crop that will never lose its destroying properties throughout the lifetime. I tell you this because I dare not withhold it. Christ paid too much for ma ...
... medication in his practice shows that he does not understand the delicate machinery of the human organism. He is introducing into the system a seed crop that will never lose its destroying properties throughout the lifetime. I tell you this because I dare not withhold it. Christ paid too much for ma ...
Tuberculosis: A Global Epidemic
... Guided by the source-case susceptibility results. If source unknown and circumstances suggest an increased risk of drug resistance, treat with standard four-drug initial-phase regimen until susceptibility pattern known. Ethambutol (EMB) can be used safely (15-20 mg/kg per day), in the likeliho ...
... Guided by the source-case susceptibility results. If source unknown and circumstances suggest an increased risk of drug resistance, treat with standard four-drug initial-phase regimen until susceptibility pattern known. Ethambutol (EMB) can be used safely (15-20 mg/kg per day), in the likeliho ...
garland3e_ppt_ch14 - York College Course and Testing System
... possession with intent to deliver A drug offense that may be proven circumstantially by proof of a monetarily valuable quantity of drugs, possession of manufacturing or packaging implements, and the activities or statements of the person or persons in possession of the substance. ...
... possession with intent to deliver A drug offense that may be proven circumstantially by proof of a monetarily valuable quantity of drugs, possession of manufacturing or packaging implements, and the activities or statements of the person or persons in possession of the substance. ...
Welcome to Week 4 7.7 Oral Delivery II
... potential projects than available resources. Projects that are not making progress will be shelved to free resources for more promising ones. Partnering with another company allows more projects to be in development. If the shared project is successful, then both companies will share in the pro ...
... potential projects than available resources. Projects that are not making progress will be shelved to free resources for more promising ones. Partnering with another company allows more projects to be in development. If the shared project is successful, then both companies will share in the pro ...
Axert - Pinky S. Tiwari, MD, PA
... cholesterol level, high blood pressure, diabetes, smoking history, family history of heart disease or stroke, obesity. Caution is also recommended in women after menopause or after removal of the ovaries, and men over 40 years old because of an increased risk for undiagnosed heart disease. Before us ...
... cholesterol level, high blood pressure, diabetes, smoking history, family history of heart disease or stroke, obesity. Caution is also recommended in women after menopause or after removal of the ovaries, and men over 40 years old because of an increased risk for undiagnosed heart disease. Before us ...
Converting oral to intravenous or subcutaneous infusions
... Levomepromazine Higher doses of diamorphine ...
... Levomepromazine Higher doses of diamorphine ...
Physical and Chemical Methods of Disinfection and Sterilization
... Various antimicrobial agents act by interfering with (1) cell wall synthesis, (2) plasma membrane integrity, (3) nucleic acid synthesis, (4) ribosomal function, and (5) folate synthesis. Action of Specific Agents Cell wall synthesis is inhibited by ß-lactams, such as penicillins and cephalosporins, ...
... Various antimicrobial agents act by interfering with (1) cell wall synthesis, (2) plasma membrane integrity, (3) nucleic acid synthesis, (4) ribosomal function, and (5) folate synthesis. Action of Specific Agents Cell wall synthesis is inhibited by ß-lactams, such as penicillins and cephalosporins, ...
COURSE TITLE - Metropolitan Community College
... List the errors which can cause a prescription to be invalid. Name the items of information that should be placed in the patient’s record when drugs are prescribed for, or administered to, a patient. Discuss the guidelines regarding telephone procedures related to drugs. Write sample prescriptions f ...
... List the errors which can cause a prescription to be invalid. Name the items of information that should be placed in the patient’s record when drugs are prescribed for, or administered to, a patient. Discuss the guidelines regarding telephone procedures related to drugs. Write sample prescriptions f ...
BioPsychoSocial Approaches to Addiction - CSAM
... Mice in the crack-cocaine group exhibited hyper-locomotion and “escape jumping” that increased with drug exposure (blue) Levels of AEME were higher than levels of cocaine Expression levels of ΔFosB were upregulated in the crack-cocaine group and levels of CREB were downregulated CB1 receptors and ca ...
... Mice in the crack-cocaine group exhibited hyper-locomotion and “escape jumping” that increased with drug exposure (blue) Levels of AEME were higher than levels of cocaine Expression levels of ΔFosB were upregulated in the crack-cocaine group and levels of CREB were downregulated CB1 receptors and ca ...
Pharmacogenomics
... We are all different. Some of our differences translate into how we react to drugs as individuals. This is why personalized medicine is important to everyone. ...
... We are all different. Some of our differences translate into how we react to drugs as individuals. This is why personalized medicine is important to everyone. ...
Integrative systems control approach for reactivating Kaposi’s
... however, the vast range of molecular machineries and regulatory circuitries forms an intertwined network that has yet to be completely mapped out.4 Analytical methods such as highthroughput bioinformatics, genomics/proteomics, and systems investigative techniques have made major advances in studying ...
... however, the vast range of molecular machineries and regulatory circuitries forms an intertwined network that has yet to be completely mapped out.4 Analytical methods such as highthroughput bioinformatics, genomics/proteomics, and systems investigative techniques have made major advances in studying ...
Preview Sample 1
... Adverse reactions are lists of possible unpleasant or dangerous secondary effects. Actions describe the cellular changes that occur as a result of the drug. Cautions are lists of conditions or types of patients that warrant closer observation for specific side effects when given the drug. Correct ! ...
... Adverse reactions are lists of possible unpleasant or dangerous secondary effects. Actions describe the cellular changes that occur as a result of the drug. Cautions are lists of conditions or types of patients that warrant closer observation for specific side effects when given the drug. Correct ! ...
When to Spare Some Pharmaceutical Care
... Clinician uncomfortable with changing or discontinuing Particularly medication prescribed by another clinician ...
... Clinician uncomfortable with changing or discontinuing Particularly medication prescribed by another clinician ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.