Herbs and Alternative Therapies in the Hypertension Clinic
... because of its reputed benefit in reducing cardiovascular disease and lowering BP. Other claims for the benefits of garlic have included cancer prevention and anti-inflammation. Studies have suggested a multitude of physiologic effects including inhibition of platelet activity and increased levels o ...
... because of its reputed benefit in reducing cardiovascular disease and lowering BP. Other claims for the benefits of garlic have included cancer prevention and anti-inflammation. Studies have suggested a multitude of physiologic effects including inhibition of platelet activity and increased levels o ...
Drug Facts Sheet Amphetamines
... Amphetamines are generally taken orally or injected. However, the addition of “ice,” the slang name of crystallized methamphetamine hydrochloride, has promoted smoking as another mode of administration. Just as “crack” is smokable cocaine, “ice” is smokable methamphetamine. Effect on mind The effect ...
... Amphetamines are generally taken orally or injected. However, the addition of “ice,” the slang name of crystallized methamphetamine hydrochloride, has promoted smoking as another mode of administration. Just as “crack” is smokable cocaine, “ice” is smokable methamphetamine. Effect on mind The effect ...
Drug Identification - The Endowment for Human Development
... emotions and motivations. Investigations have shown that THC suppresses neurons in the information-processing system of the hippocampus. In addition, researchers have discovered that learned behaviors, which depend on the hippocampus, also deteriorate. Effects on the Lungs. Someone who smokes marij ...
... emotions and motivations. Investigations have shown that THC suppresses neurons in the information-processing system of the hippocampus. In addition, researchers have discovered that learned behaviors, which depend on the hippocampus, also deteriorate. Effects on the Lungs. Someone who smokes marij ...
FullReport
... Sedatives belong to a class of drugs known as hypnotics/anxiolytics and can be divided into two sub-types; benzodiazepines and barbiturates, which act at the same neurotransmitter receptors, GABA. In low doses, sedatives produce a general feeling of relaxation and anxiety reduction. At higher doses, ...
... Sedatives belong to a class of drugs known as hypnotics/anxiolytics and can be divided into two sub-types; benzodiazepines and barbiturates, which act at the same neurotransmitter receptors, GABA. In low doses, sedatives produce a general feeling of relaxation and anxiety reduction. At higher doses, ...
Clinical uses Chronic Hypertension
... receptors, intrinsic sympathimimetic activity, in CNS effect, and in pharmacokinetics ...
... receptors, intrinsic sympathimimetic activity, in CNS effect, and in pharmacokinetics ...
Antidepressants
... Inhibits serotonin and NE reuptake Weakly inhibits dopamine reuptake Does not inhibit monoamine oxidase (MAO) Relieves depression Relieves pain of diabetic peripheral neuropathy ...
... Inhibits serotonin and NE reuptake Weakly inhibits dopamine reuptake Does not inhibit monoamine oxidase (MAO) Relieves depression Relieves pain of diabetic peripheral neuropathy ...
pegaptanib (peg-apt-i-nib)
... tach threaded plastic threader rod to the rubber stopper inside barrel of syringe. Do not pull back on plunger. ● Adequate analgesia and a broad-spectrum antibiotic should be given prior to injection. ● Intravitreal: For ophthalmic intravitreal injection only. ...
... tach threaded plastic threader rod to the rubber stopper inside barrel of syringe. Do not pull back on plunger. ● Adequate analgesia and a broad-spectrum antibiotic should be given prior to injection. ● Intravitreal: For ophthalmic intravitreal injection only. ...
IVG. Well-established Second Messengers Ca++
... Toxic effects of a drug on humans or animals can also be assessed by plotting the cumulative frequency distribution of responders vs. the log dose. As for the therapeutic effects, potentially toxic effects of drugs display a distribution similar to a Gaussian normal curve in people or animals. In or ...
... Toxic effects of a drug on humans or animals can also be assessed by plotting the cumulative frequency distribution of responders vs. the log dose. As for the therapeutic effects, potentially toxic effects of drugs display a distribution similar to a Gaussian normal curve in people or animals. In or ...
Isolation and Purification of Marine Organisms by Gary Witman, MD
... New drug agents are being isolated from marine organisms and finding their way into clinical practice. Ziconotide (Prialt) is a novel non-opioid, non local anesthetic, developed for the treatment of severe chronic pain. Ziconotide is the synthetic form of a 25 amino acid peptide isolated from the ve ...
... New drug agents are being isolated from marine organisms and finding their way into clinical practice. Ziconotide (Prialt) is a novel non-opioid, non local anesthetic, developed for the treatment of severe chronic pain. Ziconotide is the synthetic form of a 25 amino acid peptide isolated from the ve ...
PowerPoint_Chapter1
... name of a drug during this process? Answer: A generic drug name is assigned to a medical molecule by a government agency and is used during Phase I, II, and III clinical trials. Near the end of Phase III, a brand name is assigned by the company that will manufacture and sell the drug. Question 2: Wh ...
... name of a drug during this process? Answer: A generic drug name is assigned to a medical molecule by a government agency and is used during Phase I, II, and III clinical trials. Near the end of Phase III, a brand name is assigned by the company that will manufacture and sell the drug. Question 2: Wh ...
New Drug Update
... No rebound insomnia or withdrawal after 3 and 12 months Side effect incidence similar across age ranges ...
... No rebound insomnia or withdrawal after 3 and 12 months Side effect incidence similar across age ranges ...
PPT here
... Timolol and Epinephrine in the treatment of glaucoma. Lipophilic ester prodrugs of these drugs have a better intraocular penetration enabling a reduction in dose and thus adverse effects are minimised. • the therapeutic index of alkyl ester prodrugs of timolol increased by 16times. • the therapeut ...
... Timolol and Epinephrine in the treatment of glaucoma. Lipophilic ester prodrugs of these drugs have a better intraocular penetration enabling a reduction in dose and thus adverse effects are minimised. • the therapeutic index of alkyl ester prodrugs of timolol increased by 16times. • the therapeut ...
Depressants Barbiturates CNS Depressants Opiates
... • A hallucinogen (huh LOO sih nuh jun) is a drug that distorts perception, thought, and mood. ...
... • A hallucinogen (huh LOO sih nuh jun) is a drug that distorts perception, thought, and mood. ...
Lecture 9 (Anticoags) 1. What is hemostasis? 2. What is thrombosis
... 4. What are the 4 classes of antiarrhythmics? 5. You have a patient with an arrhythmia that you need to place on a drug that will moderately block Na+ channels and ultimately prolong action potential duration and increase effective refractory period. Which drug would you NOT choose? a. Disopyramide ...
... 4. What are the 4 classes of antiarrhythmics? 5. You have a patient with an arrhythmia that you need to place on a drug that will moderately block Na+ channels and ultimately prolong action potential duration and increase effective refractory period. Which drug would you NOT choose? a. Disopyramide ...
- Celon Pharma
... The objective of the CELONKO project is preclinical and clinical development of a new anti-cancer drug targeting fibroblast growth factor receptors (FGFRs). As a result of R&D works, a selective, small-molecule FGFR inhibitor will be obtained. It will be possible to use this drug in the fight agains ...
... The objective of the CELONKO project is preclinical and clinical development of a new anti-cancer drug targeting fibroblast growth factor receptors (FGFRs). As a result of R&D works, a selective, small-molecule FGFR inhibitor will be obtained. It will be possible to use this drug in the fight agains ...
Schedule 7 - Amazon Web Services
... • Cannabis is classified under Schedules I and IV of the 1961 United Nations (UN) Single Convention on Narcotic Drugs, making it subject to special restrictions. • In SA, cannabis is controlled in line with the 1961 Single Convention and is listed as a banned substance in Schedule 7. • Section 22A ( ...
... • Cannabis is classified under Schedules I and IV of the 1961 United Nations (UN) Single Convention on Narcotic Drugs, making it subject to special restrictions. • In SA, cannabis is controlled in line with the 1961 Single Convention and is listed as a banned substance in Schedule 7. • Section 22A ( ...
PRODUCT MONOGRAPH PROGLYCEM® Diazoxide capsules
... pancreatic beta cells (See TOXICOLOGY).44,45 Since there are no adequate data on fetal effects of this drug when given to pregnant women, safety in pregnancy has not been established. When the use of PROGLYCEM® in pregnant women is considered, the indications should be limited to those specified abo ...
... pancreatic beta cells (See TOXICOLOGY).44,45 Since there are no adequate data on fetal effects of this drug when given to pregnant women, safety in pregnancy has not been established. When the use of PROGLYCEM® in pregnant women is considered, the indications should be limited to those specified abo ...
Lehman Brothers 2008 Global Healthcare Conference
... All mentions and descriptions of Recordati products are intended solely as information on the general nature of the company’s activities and are not intended to indicate the advisability of administering any product in any particular instance. Recordati, established in 1926, is a European pharmaceut ...
... All mentions and descriptions of Recordati products are intended solely as information on the general nature of the company’s activities and are not intended to indicate the advisability of administering any product in any particular instance. Recordati, established in 1926, is a European pharmaceut ...
Hallucinogens - People Server at UNCW
... Are doses used in preclinical research too high? • neurotoxic doses in non-humans (5-20 mg/kg twice or more/day for several days) are generally higher than would be typical of human use. • However, people often take several tablets at a time or throughout a night’s binge and a tablet may contain up ...
... Are doses used in preclinical research too high? • neurotoxic doses in non-humans (5-20 mg/kg twice or more/day for several days) are generally higher than would be typical of human use. • However, people often take several tablets at a time or throughout a night’s binge and a tablet may contain up ...
Enhancing Solubility And Dissolution Rate of A Poorly
... Starch Glycolate, and Crospovidone in different concentrations. Tablets containing Ac- Di- Sol showed superior organoleptic properties, along with excellent in vitro and in vivo dispersion time and drug release, as compared to other formulations. 12 4. Godge RK et al., have prepared fast dissolving ...
... Starch Glycolate, and Crospovidone in different concentrations. Tablets containing Ac- Di- Sol showed superior organoleptic properties, along with excellent in vitro and in vivo dispersion time and drug release, as compared to other formulations. 12 4. Godge RK et al., have prepared fast dissolving ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.