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Guided notes 2013 Sections 1 and 2 KEY
Guided notes 2013 Sections 1 and 2 KEY

... Step 1: In a Southern blot, the DNA from each bacterial clone colony is isolated and cut into fragments by restriction enzymes. Step 2: The DNA fragments are separated by gel electrophoresis, a technique that uses an electric field within a gel to separate molecules by their size. Step 3: The DNA ba ...
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PAN Shen Quan
PAN Shen Quan

... including plant, yeast, fungal and human cells. This DNA transfer represents the only known example of interkingdom transfer of genetic information. We adopt a molecular genetic approach to identify both bacterial and eukaryotic genes responsible for the transfer process. With a combination of molec ...
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Aim: What is the structure of the DNA molecule?

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Transcription is the process by which RNA polymerase copies a
Transcription is the process by which RNA polymerase copies a

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Defined - cloudfront.net

... • Somatic cell mutations – Affect only the individual – Not passed on to future generations – Ex: Muscle cell mutation • Germ cell mutations – Germ cells = the diploid cells that undergo meiosis to make sperm & egg – May be passed to future generations ...
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de novo

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this certificate as PDF
this certificate as PDF

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DNA cloning yields multiple copies of a gene or
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Genetic Engineering Notes 2017

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Bacteria Notes File

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Unit 5 Review
Unit 5 Review

... 13. Number the steps of DNA replication in the correct order (1, 2, 3) _______ Daughter strands are formed using complementary base pairing. _______ DNA unwinds. _______ The DNA of the daughter strands winds with together with its parent strand. 14. Show the complimentary base pairing that would oc ...
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Recombinant DNA Simulation

... Introduction: One of the most important processes developed by biotechnologists was the procedure where a gene is removed from the DNA of one organism and inserted into the DNA of another organism. This technique is called Recombinant DNA. The entire procedure is dependent upon using the correct res ...
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Model question Paper- Gene Technology MLAB 475

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Molecular Pathology - Charles River Laboratories

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Biology Spring Semester Final Exam Review

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Topic 12 DNA Technology
Topic 12 DNA Technology

... 2. Obtain a plasmid (circular DNA) from bacteria 3. Use restriction enzymes to cut out the gene of interest and to cut the plasmid to receive the gene 4. Mix source DNA gene with plasmid to form recombinant DNA 5. DNA ligase will seal the phosphodiester bonds 6. Insert recombinant DNA into host cell ...
Genetic Information DNA - Barnegat Township School District
Genetic Information DNA - Barnegat Township School District

... • Results in the wrong base pair sequence • Can cause serious damage – wrong amino acid – protein non functional • Can be silent – no change in amino acid, no change in protein: - UUU changed to UUC – both are codons for the same amino acid Phenylalanine ...
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Molecular cloning



Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules. Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine.In a conventional molecular cloning experiment, the DNA to be cloned is obtained from an organism of interest, then treated with enzymes in the test tube to generate smaller DNA fragments. Subsequently, these fragments are then combined with vector DNA to generate recombinant DNA molecules. The recombinant DNA is then introduced into a host organism (typically an easy-to-grow, benign, laboratory strain of E. coli bacteria). This will generate a population of organisms in which recombinant DNA molecules are replicated along with the host DNA. Because they contain foreign DNA fragments, these are transgenic or genetically modified microorganisms (GMO). This process takes advantage of the fact that a single bacterial cell can be induced to take up and replicate a single recombinant DNA molecule. This single cell can then be expanded exponentially to generate a large amount of bacteria, each of which contain copies of the original recombinant molecule. Thus, both the resulting bacterial population, and the recombinant DNA molecule, are commonly referred to as ""clones"". Strictly speaking, recombinant DNA refers to DNA molecules, while molecular cloning refers to the experimental methods used to assemble them.
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