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The influence of James and Darwin on Cajal and his
The influence of James and Darwin on Cajal and his

... nervous system in such a way that the lower centers respond to sensory stimulus, while the cerebral hemispheres are responsible for perception and conscious actions. Perceptions involve the grouping of sensations while conscious considerations are expectations of sensations to be felt based on previ ...
Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal
Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal

... 1994; Weinberger and Berman 1996). Although the causes for such malfunction may be complex, many studies suggest abnormalities that occur during early postnatal development (Jones 1997; Lewis and Levitt 2002; Raedler et al. 1998). Electrical activities play important roles in developmental processes ...
Physiological Plasticity of Single Neurons in Auditory Cortex of the
Physiological Plasticity of Single Neurons in Auditory Cortex of the

... conditioning on secondary and primary (AI) auditory cortex indicates that both regions develop neuronal discharge plasticity early in the conditioning phase and that increases in background activity in primary auditory cortex are also associated with elevated levels of tonic arousal. In addition, th ...
Signal Integration in Thalamus: Labeled Lines Go
Signal Integration in Thalamus: Labeled Lines Go

... convergence that Rompani et al. (2017) observed was especially surprising and indeed challenges another dogma in the field and one that is deeply engrained in the current textbooks. A central tenet of neurobiology is that neurons in the LGN are monocular; they receive synaptic drive from and therefo ...
Fast Readout of Object Identity from Macaque Inferior Temporal Cortex
Fast Readout of Object Identity from Macaque Inferior Temporal Cortex

... the classifier to learn the map between neuronal responses and scale or position, irrespective of object identity (fig. S4A). Reading out object position or scale had a similar time course to the readout of object category (fig. S4B). There was little correlation between the ability of each IT site ...
PDF - Center for Neural Science
PDF - Center for Neural Science

... that such a process would be the physiological basis of a transient ‘memory’ of the stimulus” (Hebb, 1949, p. 61). The characteristic horizontal connections found in the superficial layers II–III of the monkey dorsolateral PFC may provide the anatomical substrate for such a recurrent circuit (Kritze ...
The yin and yang of cortical layer 1
The yin and yang of cortical layer 1

... where on the soma, axon and dendritic tree of L5 pyramidal neurons the different inhibitory neurons of the cortical network connect (Fig. 1a). These data are invaluable for predicting the inhibitory neurons’ influence on the firing properties of pyramidal neurons. Of particular interest in this rega ...
Chapter 16: Neural Integration II: The Autonomic Nervous System
Chapter 16: Neural Integration II: The Autonomic Nervous System

... • Is an important aspect of ANS function: – if nerve is inactive under normal conditions, can only increase activity – if nerve maintains background level of activity, can increase or decrease activity ...
PROJECT FIRST STEP&#174
PROJECT FIRST STEP®

... activity) is the first sensory system to mature. In this system, the inner ear’s semicircular canals and the vestibular nuclei are an information gathering and feedback source for movements. Those impulses travel through nerve tracts back and forth from the cerebellum to the rest of the brain, inclu ...
Bayesian Spiking Neurons II: Learning
Bayesian Spiking Neurons II: Learning

... Hebbian-style learning rules (Hebb, 1949) find such correlations (Hebb, 1984; Bishop, 1995; Bell & Sejnowski, 1995) and have strong experimental support (Bliss & Collingridge, 1993). However, recent evidence suggests that synaptic long-term plasticity rules depend not only on the average coactivatio ...
physiological plasticity in auditory cortex: rapid induction by learning
physiological plasticity in auditory cortex: rapid induction by learning

... and Diamond, in press), and wherever possible, are referenced in the text rather than repeated here. 2. Perspectives on Neuroplasticity Neuroplasticity has become a major focus in contemporary neurobiology. It is widely studied at several levels--subcellular, cellular, neuronal systems, behavioral-- ...
Metabolic acidosis inhibits hypothalamic warm
Metabolic acidosis inhibits hypothalamic warm

... THE PREOPTIC AREA and anterior hypothalamus (POAH) is regarded as the primary site for thermoreception in the mammalian brain. Peripheral thermal afferents synapse on temperature-sensitive neurons in the POAH. The POAH, in particular, contains a high concentration of warm-sensitive neurons, which ar ...
Evolution and intelligence: beyond the argument
Evolution and intelligence: beyond the argument

... critique of adaptationism). He also points out that chance historical contingencies may play a rather major role as well. Most evolutionary theorists, however, suggest that the conditions under which species level selection could contribute a significant adaptive result are quite restrictive and gen ...
The Features and Functions of Neuronal Assemblies: Possible
The Features and Functions of Neuronal Assemblies: Possible

... Signaling Mechanisms Mediating Neuronal Assemblies ...
ARTIFICIAL INTELLIGENCE APPLIED TO REAL ESTATE
ARTIFICIAL INTELLIGENCE APPLIED TO REAL ESTATE

... with legs, rather than wheels, to access dangerous slopes (e.g. in volcanic areas). The results have been frustrating, not only because of the complexity of imitating the structure of human legs, but also because the computer that controls their movement has problems processing the enormous amount o ...
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence
Michael Arbib: CS564 - Brain Theory and Artificial Intelligence

... Michael Arbib CS564 - Brain Theory and Artificial Intelligence, USC, Fall 2001. Lecture 11. Five Projects ...
On the Role of Biophysical Properties of Cortical Neurons in Binding
On the Role of Biophysical Properties of Cortical Neurons in Binding

... Here we demonstrate, Žrst, that the spatial scale of synchronization and desynchronization can be modulated to achieve context-dependent binding and segmentation of input stimuli. Second, we show that the strength of modulatory input, acting on the leakage current, can be used to bias the interactio ...
SHORT COMMUNICATION Localization of a vocal pattern generator
SHORT COMMUNICATION Localization of a vocal pattern generator

... before and during vocalization; none of them was active during mastication, swallowing or quiet respiration. Furthermore, the neuronal activity of these neurons reflected acoustic features, such as call duration or syllable structure of frequency-modulated vocalization, directly. Based on these find ...
Impact of thousand-and-one amino acid 2 kinase
Impact of thousand-and-one amino acid 2 kinase

... hypotheses of deficit an impaired mirror neuron function in autism have now been well supported by studies employing a range of methodologies. However, underlying mechanisms require further exploration to explain how mirror neurons may be involved in attention and metalizing processes. It seems poss ...
A Neuron Play - Web Adventures
A Neuron Play - Web Adventures

... Messages travel through the nervous system by means of an electrochemical process called neurotransmission. A key component in this process is the neuron, a nerve cell that is specialized to transmit and receive information. In this activity the students will model a neuron circuit to learn how it f ...
Epilepsy in Small
Epilepsy in Small

... we restricted our analyses to one-dimensional “rings” of neurons. Because organization of the synaptic connections within cortical regions is neither a lattice of nearest-neighbor connections nor completely randomly connected (Mountcastle, 1997; Gonzalez-Burgos et al., 2000; McCormick and Contreras, ...
Introduction to Psychology
Introduction to Psychology

... cell body of the receiving neuron. This tiny gap is called the synaptic gap or cleft. ...
rapid eye movement sleep deprivation induces acetylcholinesterase
rapid eye movement sleep deprivation induces acetylcholinesterase

... Using the flower-pot method, adult male albino rats were deprived of REM sleep for a period of72, 96, and 120 h and perfused brains were then sectioned with a vibratome and stained histochemically for AchE. In comparison to control animals, marked positive AchE ...
Olfactory network dynamics and the coding of multidimensional
Olfactory network dynamics and the coding of multidimensional

... not always choose between acquisition and recognition modes. ...
cerebral cortex - krigolson teaching
cerebral cortex - krigolson teaching

... the thalamus. Major projections from other cortical areas include those from the parietal cortex and certain frontal areas. MA: Primary motor area; SMA: supplementary motor area; PMA: premotor area. ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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