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consciousness as an afterthought
consciousness as an afterthought

... activating system in the brain stem”, since abbreviated as RAS. The RAS can be damaged in many ways (e.g., trauma in auto accidents) but a stroke involving the basilar artery of the brain supplying the pons is a common cause. Such patients are conscious and may have no loss of cognitive powers (we n ...
Chapter 12 *Lecture PowerPoint  Nervous Tissue
Chapter 12 *Lecture PowerPoint Nervous Tissue

... – Describe three functional properties found in all neurons. – Define the three most basic functional categories of neurons. – Identify the parts of a neuron. – Explain how neurons transport materials between the cell body and tips of the axon. ...
“Epileptic Neurons” in Temporal Lobe Epilepsy
“Epileptic Neurons” in Temporal Lobe Epilepsy

... TLE have focused on the analysis of epilepsy-related changes in synaptic connections between neurons. A striking structural change found in hippocampi of both epileptic animals and humans is sprouting of excitatory axons and formation of new synaptic contacts on surviving neurons (5, 28, 34). A numb ...
The Discovery of the Reward Pathway
The Discovery of the Reward Pathway

... injection. On the other hand, stimulation of the nucleus accumbens in the brain of the rat on the right WOULD cause activation of the Reward Pathway, and thus the behavior would be repeated. (Note: this cartoon is an exaggeration, but it drives home the point that the reward pathway has very specifi ...
embj201488977-sup-0010-Suppl
embj201488977-sup-0010-Suppl

... engagement in CRH neurons. (A) Secretagogin can affect CRH release either indirectly, by affecting the function of key proteins involved in the vesicle formation and cargo along the axons to the median eminence (“vesicle logistics”), or more directly, by Ca2+-dependent modulation of the exocytosis m ...
APPLICATION FOR MRC STUDENTSHIPS TO COMMENCE 2009
APPLICATION FOR MRC STUDENTSHIPS TO COMMENCE 2009

... mutations in Nolz1. We will generate mouse lines that will allow is to study “early” and “late” roles of Nolz1 in VTA neurons. In addition, we will use embryonic stem (ES) cell derived mDA neurons to analyse genome wide gene expression changes upon ablation of Nolz1 function. Recently, we have shown ...
Changes in muscle coordination with training
Changes in muscle coordination with training

... Stability and adaptability. To appreciate the potentially beneficial effects of increases in strength in complex natural tasks, it is necessary to also consider the context in which muscle actions are performed. Tasks encountered in daily living seldom involve a single muscle. The potential contribu ...
Chapter 12
Chapter 12

... 12-3 Describe the locations and functions of the various types of neuroglia. 12-4 Explain how the resting potential is created and maintained. 12-5 Describe the events involved in the generation and propagation of an action potential. 12-6 Discuss the factors that affect the speed with which action ...
Time-delay-induced phase-transition to synchrony in coupled
Time-delay-induced phase-transition to synchrony in coupled

... comparable to time-scales of neuronal oscillations are known to have significant effects in the ensemble activity of neurons. Thus, in modeling studies of neurons and networks, the influence of time delays on the ensemble activity has received a great deal of attention recently.4–16 In networks of c ...
Structural Changes in AMPA-Receptive Neurons in the Nucleus of
Structural Changes in AMPA-Receptive Neurons in the Nucleus of

... normotensive (Wistar-Kyoto) rats at the light microscopic and electron microscopic levels. There were more GluR1-containing dendritic spines in the nucleus of the solitary tract of hypertensive rats compared with normotensive rats, which was attributable to an increase in the proportion of dendritic ...
A Self-Organizing Neural  Network  That  Learns  to
A Self-Organizing Neural Network That Learns to

... predictions of its future appearance,and they reorganize themselves to generate better predictions. If the predictivity principle were satisfied (i.e., a visual system generates perfect predictions of the appearance of its view of the world, downto the last image detail), then dearly we could infer ...
Neurodevelopmental mechanisms of schizophrenia: understanding
Neurodevelopmental mechanisms of schizophrenia: understanding

... association studies in more than one ethnic group [9]. Compelling genetic evidence for DISC1 was initially obtained from a large Scottish pedigree in which a majority of family members with disruption of DISC1 suffer from psychiatric illnesses, including SZ [10,11]. Biological studies have revealed ...
Pain
Pain

... Images courtesy of Bentham Science Publishers. 1. Rajkowska G, et al. CNS Neurol Disord Drug Targets. 2007;6:219–233. Copyright © 2007 Bentham Science Publishing Ltd. 2. Rajkowska G, et al. Biol Psychiatry. 1999;45:1085–1098. 3. Ongür D, et al. Proc Natl Acad Sci USA. 1998;95:13290– 13295. 4. Si X, ...
Monitoring and switching of cortico-basal ganglia loop
Monitoring and switching of cortico-basal ganglia loop

... information and were found to be insensitive to stimulus size, shape, and brightness but responsive to changes in the visual scene (Schlag and Schlag-Rey, 1984). Recently, Matsumoto and others who examined single neuron responses in the primate CM–Pf complex to visual, auditory, and tactile stimuli ...
Fatigue and Inhibition
Fatigue and Inhibition

... explains the association of ideas and sensory-motor associations, and there is good reason to think that something of the kind does happen. How might it work? Figure 29 shows what is implied concerning individual neurons at the synapse. Two brain activities A and B are excited at the same time. This ...
Baars - neurofeedback - Aspen2008
Baars - neurofeedback - Aspen2008

... 10. Chronic pain, fibromyalgia - cortical pain may depend on slow rhythms. This is not to say that these are mature, well-tested treatments. However, the very wide range and robust short-term effects are quite remarkable. They tell us something fundamental about consciousness, and suggest important ...
The Nervous System Organization of the Nervous System
The Nervous System Organization of the Nervous System

... Neural Cortex: gray matter on the surface of the brain. Tracts: bundles of axons within CNS that share common origin, destination and function. Columns: groups of tracts. Pathways: avenues that link brain centers to rest of the body (sensory pathways ‡ bring information to brain; motor pathways ‡ tr ...
Role of the Preoptic-Anterior Hypothalamus in
Role of the Preoptic-Anterior Hypothalamus in

... integrate central and peripheral thermal information. As a result of this sensory integration and its control over lower effector areas, the preoptic region elicits the thermoregulatory responses that are the most appropriate for both internal and environmental thermal conditions. Thermosensitive pr ...
Pointing the way toward target selection
Pointing the way toward target selection

... regions along a sensory pathfeatures in the parietal cortical Feedforward input way can be divided into three area LIP10. The selection of a broad classes: feedforward, Fig. 1. The pointer circuit architecture. Feedforward connections carry single target requires that inhirecurrent and top-down 2 . ...
view - E-LIB Bremen - Universität Bremen
view - E-LIB Bremen - Universität Bremen

... only few parameters. There are competitions held where the goal is to predict the electrical behavior of neuron, and these models reach a very high accuracy in the prediction of neuronal spike times [3]. With modern supercomputer clusters, it is possible to simulate neuronal networks of spiking neur ...
Neuroimaging techniques offer new perspectives on callosal
Neuroimaging techniques offer new perspectives on callosal

... be mediated by fibers passing through the splenium. The differences in transfer time have been explained either in terms of an asymmetry of callosal fibers or as a result of hemispheric specialization. When performing probabilistic tractography (Behrens et al., 2003) from the callosum to left hemisp ...
Exam I
Exam I

... 20) If neuron X is excitatory and fires multiple action potentials to bring neuron W to threshold… A) spatial summation is occurring. B) temporal summation is occurring. C) inhibition shunting is occurring. D) All of the above are true. E) None of the above is true. 21) Based only on the location of ...
Inter-regional Contribution of Enhanced Activity of the Primary
Inter-regional Contribution of Enhanced Activity of the Primary

... excitatory neurons in response to L4 electrical stimulation. g–i, The relationship between stimulus intensity and responding cell neuronal activity elicited in response to ratio (g), amplitude of Ca 2⫹ transients (h), and response probability per cell (i). Excitability of L2/3 excitatory neurons of ...
Neurotransmitters
Neurotransmitters

... muscles move the hand from the hot flame. See how easy that is? ...
Dendritic Signal Integration
Dendritic Signal Integration

... (e) adapted from Cathala L, Brickley S, Cull-Candy S, et al. (2003) Maturation of EPSCs and intrinsic membrane properties enhances precision at a cerebellar synapse. Journal of Neuroscience 23: 6074–6085. ...
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Activity-dependent plasticity

A defining feature of the brain is its capacity to undergo changes based on activity-dependent functions, also called activity-dependent plasticity. Its ability to remodel itself forms the basis of the brain’s capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is functionally linked to plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity is the result of changed gene expression that occurs because of organized cellular mechanisms.The brain’s ability to adapt toward active functions has allowed humans to specialize in specific processes based on relative use and activity. For example, a right-handed person may perform any movement poorly with his/her left hand but continuous practice with the less dominant hand can make both hands just as able. Another example is if someone was born with a neurological disorder such as autism or had a stroke that resulted in a disorder, then they are capable of retrieving much of their lost function by practicing and “rewiring” the brain in order to incorporate these lost manners. Thanks to the pioneers within this field, many of these advances have become available to most people and many more will continue to arrive as new features of plasticity are discovered.
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