• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Poster Example
Poster Example

... physiology of neurons negatively. This study compared three different treatments of neuronal cultures in order to find a treatment that reversed the deleterious effects of removing glia from neuronal cultures. The first culture, the control, consisted of a mixture of plated neurons and glia. The sec ...
View PDF - e-Science Central
View PDF - e-Science Central

introduction the neuron doctrine
introduction the neuron doctrine

... errors"- in a gene or in the flanking regions of DNA that regulate the gene's expression. In some cases, a single protein may be grossly abnormal or missing entirely, disrupting neuronal function. An example is fragile X syndrome, a disorder that manifests as intellectual disability and autism and i ...
ANS notes filled
ANS notes filled

... Carry motor information to visceral effectors. ...
Dynamic Stochastic Synapses as Computational Units
Dynamic Stochastic Synapses as Computational Units

CHARLES UNIVERSITY
CHARLES UNIVERSITY

... ischemia caused by activation of nNOS and involved in neuronal damage but NO produced by eNOS in the same case play a protective role by maintaining regional cerebral blood flow. It is also related in numerous disorders of CNS and in the etiology of neurological conditions, including autoimmune and ...
Notes
Notes

... The neuron from which is transmitting the signal is called the presynaptic neuron and the neuron receiving the signal is called the postsynaptic neuron. The synaptic vesicles of each neuron store some neurotransmitters. When the action potential reaches the end of presynaptic neuron, these vesicles ...
Transverse mechanical properties of rat skeletal muscle
Transverse mechanical properties of rat skeletal muscle

... kinetics during compression-decompression cycle applied on rat TA. Axial and transverse twitch forces (twA, twT) were quantified by the contraction amplitude (FA-Amp, FT-Amp), time to peak contraction, and time to half relaxation. Axial twitch parameter values were normalized with respect to the ini ...
Osteo-genesis
Osteo-genesis

... System. Sympathetic system is activated during fight, flight or fright. Parasympathetic system is like the default/background setting. • Both systems have two sets of neurons in their pathway. The first neuron, that is usually located in CNS is called pre-ganglionic neuron. It synapses at a ganglion ...
Theme 6. Vision
Theme 6. Vision

... Can you describe how myelination occurs in the peripheral nervous system and by which mechanism this can have an impact on speed of transmission. (6p) ...
Lessons 1
Lessons 1

Self Assessment Chapter 11 part 2 - CM
Self Assessment Chapter 11 part 2 - CM

... • Depolarization – sodium channels open, allowing positively charged sodium ions to flow into cell; membrane potential becomes more positive (Figure 11.14a) • Repolarization – potassium ion channels open; allows positively charged potassium ions to flow out of cell; cell becomes more negative, retur ...
Nervous
Nervous

... 1. initiation and continuation of voluntary movements 2. maintenance of appropriate muscle tone against gravity (maintenace of tone in extensor muscles), coordination 3. regulation of posture (UMN modulates muscle tone activity by its control over the myotactic reflex arc /stretch receptor, muscle s ...
Spinal cord 1
Spinal cord 1

... and the body of the posterior horn  Both are present at all spinal levels.  Between the substantia gelatinosa and the surface of the cord is a relatively pale-staining area of white matter called Lissauer's tract.* ...
Neurons and Nervous Systems
Neurons and Nervous Systems

... In a chemical synapse neurotransmitters from a presynaptic cell bind to receptors in a postsynaptic cell. The synaptic cleft—about 25 nanometers wide—separates the cells. ...
The Action Potential
The Action Potential

... As we have seen in the previous article of this series, the membrane of non-stimulated neuron (at rest)presents a difference of electrical potential between the interior and exterior of the cell of approximately 70 mV; a potential, which is maintained while the cell, is alive. This constitutes the p ...
Chapter 12 - Tribiana.com
Chapter 12 - Tribiana.com

... Sustained muscle contraction fatigue is due to accumulation of extracellular K+ From K+ efflux during AP Occurs in moderate exercise as slow-twitch fibers deplete glycogen stores Fast twitch fibers are then recruited, converting glucose to lactic acid which interferes with Ca2+ transport Centra ...
Chapter 16: The Autonomic System and Higher
Chapter 16: The Autonomic System and Higher

... B. All are polysynaptic, can be long or short 1. Long reflexes coordinate activities of entire organs, involves CNS 2. Short reflexes bypass CNS and control activity in one small part of organ C. Examples of Visceral Reflexes Table 16-4 ...
high. 1, treated virgin
high. 1, treated virgin

... crosses of closely related individuals, some ferdemonstrate rigorously that single-cell tilized eggs give rise to diploid males that are homozygous for the sex alleles. These males stimulation can produce such patterns, are highly inviable. For this reason we utilized to find the sensory inputs for ...
Modulation of Synaptic Transmission to Second
Modulation of Synaptic Transmission to Second

Chapter 48
Chapter 48

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
resting potential
resting potential

... • Postsynaptic potentials fall into two categories – Excitatory postsynaptic potentials (EPSPs) are depolarizations that bring the membrane potential toward threshold – Inhibitory postsynaptic potentials (IPSPs) are hyperpolarizations that move the membrane potential farther from threshold ...
Is Cell Death Primary or Secondary in the Pathophysiology of
Is Cell Death Primary or Secondary in the Pathophysiology of

... should affect the synapse. As the physiological form of -synuclein is a presynaptically localized protein, -synuclein aggregation may start at the presynapse. To test this hypothesis we used paraffin-embedded tissue (PET) blotting, the most sensitive known method for the topographical detection of ...
Smell and Taste
Smell and Taste

... • Free Nerve Endings • Olfactory Nerve (Axons of the ORCs) ...
An octopaminergic system in the CNS of the snails, Lymnaea
An octopaminergic system in the CNS of the snails, Lymnaea

... the neuronal transmission. However, the synaptic connections formed by either OC neurons or N3p interneurons are not identical, as they make different synaptic connections with both motoneurons (B3) and feeding interneurons (N2). CGC: The cerebral, serotonergic CGC neurons excite the OC cells, but t ...
< 1 ... 51 52 53 54 55 56 57 58 59 ... 209 >

Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report