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Bio 103 Lecture Outline:
Bio 103 Lecture Outline:

... - chain reaction that spread AP along every part of the cell membrane - occurs on _________________ - 1m/sec 2. Saltatory propagation: - jumping of AP from ________ to __________ in myelinated fibers ...
Bio 103 Lecture Outline:
Bio 103 Lecture Outline:

... - chain reaction that spread AP along every part of the cell membrane - occurs on _________________ - 1m/sec 2. Saltatory propagation: - jumping of AP from ________ to __________ in myelinated fibers ...
Session 2. Synaptic Plasticity (Chair, H. Kamiguchi)
Session 2. Synaptic Plasticity (Chair, H. Kamiguchi)

52 Nerve Tissue
52 Nerve Tissue

... neuron but may be in the hundreds of thousands. Dendrites play an important role in integrating the many incoming impulses. A neuron has only one axon, which conducts impulses away from the parent neuron to other functionally related neurons or effector organs. The axon arises from the axon hillock ...
Movement
Movement

... Disorders of the Motor Neurons.  a) Myasthenia Gravis: The immune system progressively attacks acetylcholine at the neuromuscular junction.  This leads to progressive muscle weakness and rapid fatigue apparent after short periods of exercise.  Drugs such as Physostigmine (an acetylcholine agonis ...
Chapter 12 Lecture Outline
Chapter 12 Lecture Outline

... – Name the six types of cells that aid neurons and state their respective functions. – Describe the myelin sheath that is found around certain nerve fibers and explain its importance. – Describe the relationship of unmyelinated nerve fibers to their supportive cells. – Explain how damaged nerve fibe ...
Nerve Impulses and Action Potential
Nerve Impulses and Action Potential

... 6 Initial ionic conditions restored. The ionic conditions of the resting state are restored later by the activity of the sodium-potassium pump. Three sodium ions are ejected for every two potassium ions carried back into the cell. ...
pttx
pttx

... To Remember When an AP depolarizes the membrane at the synaptic terminal it 2) opens voltage-gated Ca++ channels, 3) the Ca++ that gets in causes vesicles full of neuro-transmitter to empty (4). The neurotransmitter binds to ligand-gated ion channels. The result is a post-synaptic potential (PSP). ...
histology of muscle as a tissue
histology of muscle as a tissue

... gradual process of cell lengthening with simultaneous synthesis of myofibrillar proteins. ...
Anatomy Review - Interactive Physiology
Anatomy Review - Interactive Physiology

... -5035. (Page 8.) An action potential that reaches the axon terminal causes synaptic vesicles, to fuse with it, releasing ____________ into the _________ _________. a. acetyl choline, postsynaptic neuron b. neurotransmitter, synaptic cleft 36. (Page 8.) The neuron receiving the signal is called the ...
Option E: Neurobiology and behaviour
Option E: Neurobiology and behaviour

... E.4.2 Explain how decision-making in the CNS can result from the interaction between the activities of excitatory and inhibitory presynaptic neurons at synapses. E.4.3 Explain how psychoactive drugs affect the brain and personality by either increasing or decreasing postsynaptic transmission. E.4.4 ...
NervousSystem2
NervousSystem2

... must have its origin in the cerebral cortex. Its origin is by excitation of interneurons in an area of the cerebral cortex designated the motor cortex. All stimuli ultimately contribute to effector action. Those that are consciously appreciated utilize pathways that traverse the cerebral cortex and ...
Chapter 48 – Nervous Systems
Chapter 48 – Nervous Systems

... Calcium ions (Ca2+) then diffuse into the terminal, and the rise in Ca2+ concentration in the terminal causes some of the synaptic vesicles to fuse with the terminal membrane, releasing the neurotransmitter by exocytosis. ...
The Autonomic Nervous System
The Autonomic Nervous System

... are located in the inter-mediolateral column of the thoracic and lumbar regions of the spinal cord. Shortly after the dorsal and ventral roots fuse, the myelinated sympathetic preganglionic fibers leave the spinal nerve trunk to travel to the segmentally arranged paravertebral sympathetic ganglia ch ...
Sample pages 2 PDF
Sample pages 2 PDF

... avenue in the study of neurotransmission that has started recently to be explored. Colocalization of classical neurotransmitters within single terminals was initially perceived as a curiosity and their potential co-release was viewed with skepticism. The molecular explanation, as well as the physiol ...
FIGURE LEGENDS FIGURE 29.1 Vestibular canals and otoliths. The
FIGURE LEGENDS FIGURE 29.1 Vestibular canals and otoliths. The

... FIGURE 29.4 The corticospinal projection in the macaque monkey. (A) The density of corticospinal neuronal somata is shown by stippling in this lateral view of the left cerebral hemisphere; the superior medial surface of the hemisphere is also shown (above) as if reflected in a mirror. The central su ...
Eagleman Ch 3. Neurons and Synapses
Eagleman Ch 3. Neurons and Synapses

... terminals: Small swellings that release signals to affect other neurons Chemical signals, known as neurotransmitters, cross small gaps, known as synapses.  It is estimated that there are about 500 trillion synapses in the adult brain. ...
6.5 Nervous system part1
6.5 Nervous system part1

... • Sodium Channels/ Gates – ...
The Nervous System
The Nervous System

...  As impulse move down axon, negative charges become positive, causing action potential Retrived from http://apbrwww5.apsu.edu/t hompsonj/Anatomy ...
Neuron Presentation Project
Neuron Presentation Project

... In this project you will be required to choose a neuron, research it and present it to the class. Begin by taking some time to review some of the different types of neurons here. Once you have chosen a couple of neurons that seem interesting to you, be sure to check with Mr. Silva to make sure that ...
Neural Conduction - U
Neural Conduction - U

... • thus, any time that there is an accumulation of a particular class of ions in one area, the probability is increased that random motion will move ions out of this area (because there are more ions available to leave) and the probability is decreased that random motion will move more ions into the ...
30. Autonomic NS. Sympathetic nervous system
30. Autonomic NS. Sympathetic nervous system

... – Autonomic motor neurons to smooth muscle, cardiac muscle and glands Where in the CNS? Hypothalamus and brain stem ...
Aggregation of Sodium Channels during Development and
Aggregation of Sodium Channels during Development and

... AChR subunits and channel kinetics change (Sakmann and Brenner, 1978; Mishina et al., 1986; Gu and Hall, 1988), synaptic vesicle proteins are restricted to the nerve terminal (Lupa and Hall, 1989; Dahm and Landmesser, 1991) subsynaptic folds appear (Terivainen, 1968; Kelly and Zacks, 1969) and polyn ...
Differential Permeability of the Membrane
Differential Permeability of the Membrane

... The split brain experiments show that that unified consciousness depends on the two hemispheres being able to communicate. If the corpus callosum is severed then each hemisphere begins to act and experience things independently of the other. ...
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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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