• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Rectodelt 100 mg suppositories - Biotech
Rectodelt 100 mg suppositories - Biotech

... In acute inflammatory conditions a 50mg to 100mg dose is given. In case of chronic diseases the daily dose is 30 to 50mg. • For Children: In emergency conditions it is much easier to apply Rectodlet compared to other methods of administration. The usual daily dose is 100mg. However, depending on the ...
Example Let`s take one last look at the frozen olive - Rose
Example Let`s take one last look at the frozen olive - Rose

... Let’s take one last look at the frozen olive problem. We drop a frozen olive initially at a temperature of Ti = 0°C into a martini at a temperature T∞ = 5°C. We then stir the martini with a flamingo swizzle stick resulting in a convection coefficient of h = 10 W/(m2·C°). The olive is modeled as a sp ...
The Perceptron
The Perceptron

... – If the output unit incorrectly outputs a zero, add the input vector (multiplied by the learning rate) to the weight vector. – If the output unit incorrectly outputs a 1, subtract the input vector (multiplied by the learning rate) from the weight vector. This is guaranteed to find a set of weights ...
PPT
PPT

... Inhibition effect extends beyond elimination of drug due to enzyme inactivation. Effect tends to accumulate after each dose. Inhibition effect is generally greater than predicted based on ‘reversible’ IC50 or Ki values. Most compounds will have non-linear pharmacokinetics. Rare cases of hepatotoxici ...
biliary excretion
biliary excretion

6-General anesthesia..
6-General anesthesia..

... -Morphine only with high doses, so not used ...
changes in biochemical parameters of carbohydrate metabolism
changes in biochemical parameters of carbohydrate metabolism

NUTRIENT GLOSSARY Adaptogens: Plant
NUTRIENT GLOSSARY Adaptogens: Plant

...  Alpha-Lipoic acid: An important cellular component, which is required for critical energy production steps inside the body’s cells. It can work in concert with Vitamins C and E and is an important antioxidant.  Amla: Emblica officinalis is a shrub that sometimes grows into a deciduous tree with f ...
Vitamin E May Boost Survival in People with
Vitamin E May Boost Survival in People with

... If you knew that taking vitamins would increase your lifespan would you take them? That is usually the idea behind taking them, to stay happy and healthy. Recent findings were presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago showing that Alzheimer’s patients ...
Obesity - Moodle Lille 2
Obesity - Moodle Lille 2

... • How can we evaluate the price of the new weight-management drugs? ...
in the elderly
in the elderly

오토메타형식언어 - Soft Computing Lab.
오토메타형식언어 - Soft Computing Lab.

...  different amounts of selection pressure for different times in ...
NOURIAST Tablets 20 mg
NOURIAST Tablets 20 mg

... In repeated-dose toxicity studies in mice, rats, and dogs and carcinogenicity studies in mice and rats, inflammatory changes in the lung characterized by inflammatory macrophages (development, aggregation, or increase of macrophages/foamy macrophages/histiocytes/foamy histiocytes in the alveolar spa ...
Skeletal muscle relaxants
Skeletal muscle relaxants

... • Chemically is a hydantoin derivative • It reduces skeletal muscle strength by interfering with excitation-coupling in the muscle fiber. • In detail, dantrolene bind to ryanodine receptor and blocks calcium release from sarcoplasmic reticulum . ...
Equation of a Line Problem Buster - VCC Library
Equation of a Line Problem Buster - VCC Library

... Math 0861 ...
A VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SATRANIDAZOLE,
A VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SATRANIDAZOLE,

... different days. Also, the intermediate precision of the method was determined by changing the brand of the column as well as the analyst handling the whole experiment. The results of intra-day and inter-day precision experiments are shown in Table 2. The developed method was found to be precise as t ...
12.2 Effects of Plasma Stability
12.2 Effects of Plasma Stability

... Leads containing these groups, especially peptides and peptide mimetics, should be tested for plasma stability. ...
The effect of site (deltoid or gluteus muscle) of intramuscular
The effect of site (deltoid or gluteus muscle) of intramuscular

没有幻灯片标题
没有幻灯片标题

... Part A Pharmacokinetic Processes  First-pass elimination(首过消除)  When a drug is absorbed across the GI tract, it enters the portal circulation before entering the systemic circulation. If the drug is rapidly metabolized by the liver or intestinal mucosa, the amount of unchanged drug that gains acc ...
Experiment 7
Experiment 7

Frequently Asked Questions: Opiate Dependency and Methadone
Frequently Asked Questions: Opiate Dependency and Methadone

... R.C. Baselt: Disposition of Toxic Drugs and Chemicals in Man, Fifth Edition 2000 The detection period is very much dose and half-life dependent. The larger the dose, the longer the period the drug/metabolite can be detected in the urine. Opiates may be positive for up to 2 weeks after last use with ...
unit 3 study guide
unit 3 study guide

... I can solve an equation for a specific variable and reason about the new equation. Why would we ever need to solve a formula or equation for a specific value?________________ Example: Solve the formula d = rt for t or for r. ...
Effect of drug type on the degradation rate of PLGA
Effect of drug type on the degradation rate of PLGA

... Fig. 3), as a function of the drug solubility, as measured under the same conditions as the dissolution experiments. We see that there is no direct correlation; After 3 days, the fraction of released drug seems to generally increase with solubility (with one exception, Thiothixene). However, on day ...
Extended-Release Injectable Parasiticide 5% Sterile
Extended-Release Injectable Parasiticide 5% Sterile

... The product is likely to cause tissue damage at the site of injection, including possible granulomas and necrosis. These reactions have disappeared without treatment. Local tissue reaction may result in trim loss of edible tissue at slaughter. Observe cattle for injection site reactions. If injectio ...
Fall 12, Final
Fall 12, Final

< 1 ... 84 85 86 87 88 89 90 91 92 ... 157 >

Plateau principle

The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry and system dynamics. It applies whenever a drug or nutrient is infused or ingested at a relatively constant rate and when a constant fraction is eliminated during each time interval. Under these conditions, any change in the rate of infusion leads to an exponential increase or decrease until a new level is achieved. This behavior is also called an approach to steady state because rather than causing an indefinite increase or decrease, a natural balance is achieved when the rate of infusion or production is balanced by the rate of loss.An especially important use of the plateau principle is to study the renewal of tissue constituents in the human and animal body. In adults, daily synthesis of tissue constituents is nearly constant, and most constituents are removed with a first order reaction rate. Applicability of the plateau principle was recognized during radiotracer studies of protein turnover in the 1940s by Rudolph Schoenheimer and David Rittenberg. Unlike the case with drugs, the initial amount of tissue or tissue protein is not zero because daily synthesis offsets daily elimination. In this case, the model is also said to approach a steady state with exponential or logarithmic kinetics. Constituents that change in this manner are said to have a biological half-life.A practical application of the plateau principle is that most people have experienced ""plateauing"" during regimens for weight management or training for sports. After a few weeks of progress, one seems unable to continue gaining in ability or losing weight. This outcome results from the same underlying quantitative model. This entry will describe the popular concepts as well as development of the plateau principle as a scientific, mathematical model.In the sciences, the broadest application of the plateau principle is creating realistic time signatures for change in kinetic models (see Mathematical model). One example of this principle is the long time required to effectively change human body composition. Theoretical studies have shown that many months of consistent physical training and food restriction are needed to bring about permanent weight stability in people who were previously overweight.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report