USMLE Step 1 - Becker Professional Education
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
Effete, a Drosophila chromatin-associated ubiquitin
... euchromatic bands and interbands, the TAS regions and the chromocenter. Our results suggest that Eff associates with different types of chromatin affecting their abilities to regulate gene expression. ...
... euchromatic bands and interbands, the TAS regions and the chromocenter. Our results suggest that Eff associates with different types of chromatin affecting their abilities to regulate gene expression. ...
Maternal uniparental disomyof chromosome 13
... Since Engel originally postulated the existence produced a true isochromosome since all the of UPD in 1980,' several examples have been polymorphic AC repeat alleles examined were reported involving all or part of chromosomes homozygous despite all being highly (>75%) 6,7,11,14,15,16,21,22, and the ...
... Since Engel originally postulated the existence produced a true isochromosome since all the of UPD in 1980,' several examples have been polymorphic AC repeat alleles examined were reported involving all or part of chromosomes homozygous despite all being highly (>75%) 6,7,11,14,15,16,21,22, and the ...
Revisiting Plus-Strand DNA Synthesis in Retroviruses and Long
... as the first g:C base pair upstream of the PPT/U3 junction (note that throughout the manuscript, RNA and DNA bases have been represented in lower and upper case, respectively). Collectively designated the “unzipped” portion, X-ray crystallography provided the first notion that PPT structural malleab ...
... as the first g:C base pair upstream of the PPT/U3 junction (note that throughout the manuscript, RNA and DNA bases have been represented in lower and upper case, respectively). Collectively designated the “unzipped” portion, X-ray crystallography provided the first notion that PPT structural malleab ...
Synthesis and Evaluation of Guanidino Phthalocyanines for G
... strongly suggesting a regulatory role in vivo. In vitro studies have already shown that these repeats can fold into triple helix-containing structures called H-DNA. Upon H-DNA formation, the DNA double helix within one-half of the H-palindrome denatures into two single strands, and one of these comp ...
... strongly suggesting a regulatory role in vivo. In vitro studies have already shown that these repeats can fold into triple helix-containing structures called H-DNA. Upon H-DNA formation, the DNA double helix within one-half of the H-palindrome denatures into two single strands, and one of these comp ...
The promiscuous primase
... of the Pol X family of DNA-repair polymerases. Furthermore, two additional groups of enzymes, the ligase/ primase of the bacterial nonhomologous end-joining machinery and a putative replicase from an archaeal plasmid have shown striking functional and structural similarities to the core primase. The ...
... of the Pol X family of DNA-repair polymerases. Furthermore, two additional groups of enzymes, the ligase/ primase of the bacterial nonhomologous end-joining machinery and a putative replicase from an archaeal plasmid have shown striking functional and structural similarities to the core primase. The ...
The DnaE polymerase from Deinococcus radiodurans features
... competence, D. radiodurans does also feature additional and peculiar biochemical properties responsible for genome integrity maintenance. In particular, when considering that ionizing radiations induce severe oxidative stress, it was realized that the radiation-resistance of D. radiodurans is mainly ...
... competence, D. radiodurans does also feature additional and peculiar biochemical properties responsible for genome integrity maintenance. In particular, when considering that ionizing radiations induce severe oxidative stress, it was realized that the radiation-resistance of D. radiodurans is mainly ...
Isolation and characterization of a repeated sequence (RPS1) of
... described previously (Iwaguchi et a/., 1990) using C. albicans cloned fragments of plasmids and chromosome 6 of strain FC18 prepared by the method described above. The intensity of hybridization signal with the probes was measured with the BAS2000 image analyser system (Fuji Film Co.). The signal in ...
... described previously (Iwaguchi et a/., 1990) using C. albicans cloned fragments of plasmids and chromosome 6 of strain FC18 prepared by the method described above. The intensity of hybridization signal with the probes was measured with the BAS2000 image analyser system (Fuji Film Co.). The signal in ...
Review A model for chromosome structure during the mitotic
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
... Figures 1^11 (overleaf). Diagrammatic representations of chromosome structure through the mitotic cell cycle. Drawings are not to scale. Telophase/G1 . (A) Longitudinal view of a segment of a decondensing chromosome during telophase or a decondensed chromosome during G1. The anaphase chromosome core ...
13 The Klenow fragment of DNA polymerase I Pol I actually appears
... also lie at the base of the palm. As we shall see later, it is these acidic residues that bind the Mg 2+ ions that are essential for catalysis. The second substrate, dNTP, is bound by a pocket in the fingers domain. Interestingly, there are no hydrogen bonds formed between the enzyme and the new bas ...
... also lie at the base of the palm. As we shall see later, it is these acidic residues that bind the Mg 2+ ions that are essential for catalysis. The second substrate, dNTP, is bound by a pocket in the fingers domain. Interestingly, there are no hydrogen bonds formed between the enzyme and the new bas ...
RecA-mediated strand exchange traverses
... This result is consistent with the notion that the efficient strand exchange detected on the gels shown in the Figure 1 can be attributed to spontaneous RecA-independent branch migration that occurred only after deproteinization of joint molecules and, therefore, is not a result of RecA action. Pany ...
... This result is consistent with the notion that the efficient strand exchange detected on the gels shown in the Figure 1 can be attributed to spontaneous RecA-independent branch migration that occurred only after deproteinization of joint molecules and, therefore, is not a result of RecA action. Pany ...
Snímek 1
... How a supernumerary B chromosome survives over time? transmission higher than Mendelian kept in populations drive (pre-meiotic, meiotic, post-meiotic) = preferential maintenance of Bs post-meiotic drive common in plants during gametophyte maturation (examples: rye, maize) ...
... How a supernumerary B chromosome survives over time? transmission higher than Mendelian kept in populations drive (pre-meiotic, meiotic, post-meiotic) = preferential maintenance of Bs post-meiotic drive common in plants during gametophyte maturation (examples: rye, maize) ...
No Slide Title
... Low Mutation Rates are Necessary for the Evolution of Complexity 1. Because most mutations are deleterious, there are limits to the number of mutations that an organism can afford to accumulate in its somatic body, e.g., a) given mean eukaryotic rates, genomes can accommodate 60,000 genes without i ...
... Low Mutation Rates are Necessary for the Evolution of Complexity 1. Because most mutations are deleterious, there are limits to the number of mutations that an organism can afford to accumulate in its somatic body, e.g., a) given mean eukaryotic rates, genomes can accommodate 60,000 genes without i ...
Full-Text PDF
... complex of DNA primase and DNA polymerase α (Polα) [1]. The primosome initiates synthesis of both the leading and lagging strands by making chimeric RNA-DNA primers, which are required for the loading of replication factor C (RFC), proliferating cell nuclear antigen (PCNA), and replicative DNA polym ...
... complex of DNA primase and DNA polymerase α (Polα) [1]. The primosome initiates synthesis of both the leading and lagging strands by making chimeric RNA-DNA primers, which are required for the loading of replication factor C (RFC), proliferating cell nuclear antigen (PCNA), and replicative DNA polym ...
CHROMOSOMES AND DISEASE
... history when many new lands and races were being discovered and described for the first time. Thus the name suggested for people with this specific disability was Mongolism. Today the disorder is more appropriately referred to as Down syndrome or trisomy 21. The disorder results from an abnormality ...
... history when many new lands and races were being discovered and described for the first time. Thus the name suggested for people with this specific disability was Mongolism. Today the disorder is more appropriately referred to as Down syndrome or trisomy 21. The disorder results from an abnormality ...
Coordination of replication and transcription along a Drosophila
... et al. 2002) replication timing studies using incomplete arrays of cDNAs have demonstrated a correlation between time of replication and the probability that a specific gene is expressed, it remained to be determined what step(s) in the replication initiation process are influenced by transcription. ...
... et al. 2002) replication timing studies using incomplete arrays of cDNAs have demonstrated a correlation between time of replication and the probability that a specific gene is expressed, it remained to be determined what step(s) in the replication initiation process are influenced by transcription. ...
From the Department of Zoology, University of
... of these units per chromosome has not been determined yet, there is evidence that it may not be the same in all species (9, 10). For some time now the nature of the longitudinal differentiation of chromosomes into chromomeres, interchromomeric fibers, hetero-, and euchromatin has been debated. Some ...
... of these units per chromosome has not been determined yet, there is evidence that it may not be the same in all species (9, 10). For some time now the nature of the longitudinal differentiation of chromosomes into chromomeres, interchromomeric fibers, hetero-, and euchromatin has been debated. Some ...
Regulation of DNA Polymerase Exonucleolytic Proofreading Activity
... some residues in the C-terminal domain, the location of residues A737 and A777 (Figure 1), are in close contact with the exonuclease domain (see Nossal 1998). Amino acid substitutions that produce the antimutator phenotype were also identified in the polymerase active center, but the polymerase and ...
... some residues in the C-terminal domain, the location of residues A737 and A777 (Figure 1), are in close contact with the exonuclease domain (see Nossal 1998). Amino acid substitutions that produce the antimutator phenotype were also identified in the polymerase active center, but the polymerase and ...
Cleavage of a model DNA replication fork by a Type I restriction
... status of the chromosome, for example, via DNA methylation. Loss of DNA methylation may occur through replication recovery after fork collapse as previously proposed: processing of a double-strand DNA end with RecBCD enzyme, homologous pairing and D-loop formation with RecA, and establishment of a n ...
... status of the chromosome, for example, via DNA methylation. Loss of DNA methylation may occur through replication recovery after fork collapse as previously proposed: processing of a double-strand DNA end with RecBCD enzyme, homologous pairing and D-loop formation with RecA, and establishment of a n ...
A novel assay for examining the molecular
... loaded on the DNA by RF-C (11–18, reviewed in 2,19,20). On the leading strand, PCNA is thought to be loaded once to establish a processive polymerase complex which can synthesize long stretches of DNA without further modification. On the lagging strand, each Okazaki fragment is initiated after synth ...
... loaded on the DNA by RF-C (11–18, reviewed in 2,19,20). On the leading strand, PCNA is thought to be loaded once to establish a processive polymerase complex which can synthesize long stretches of DNA without further modification. On the lagging strand, each Okazaki fragment is initiated after synth ...
What is Cytogenetics?
... of a chromosome or three. • Therefore, if a duplication exists, that person has three copies of that area instead of two. • This means there are extra instructions (genes) present that can cause an increased risk for birth defects or developmental problems. ...
... of a chromosome or three. • Therefore, if a duplication exists, that person has three copies of that area instead of two. • This means there are extra instructions (genes) present that can cause an increased risk for birth defects or developmental problems. ...
G-quadruplex and G-rich sequence stimulate Pif1p
... C The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, ...
... C The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, ...
AP Bio Chapter 16-20 Practice test
... ____ 15. Eukaryotic telomeres replicate differently than the rest of the chromosome. This is a consequence of ...
... ____ 15. Eukaryotic telomeres replicate differently than the rest of the chromosome. This is a consequence of ...
Characterization of a novel DNA polymerase activity assay enabling
... tool with far-reaching applications such as, but not limited to, screening candidate-polymerase inhibitors in vitro, or detecting the presence any microbe (harboring active DNA polymerases) within a diverse range of sample types. If intended for these purposes, routine use of traditional polymerase ...
... tool with far-reaching applications such as, but not limited to, screening candidate-polymerase inhibitors in vitro, or detecting the presence any microbe (harboring active DNA polymerases) within a diverse range of sample types. If intended for these purposes, routine use of traditional polymerase ...
Activity Name - Science4Inquiry.com
... Inversion Mutation: reverse one section of bases (a whole gene) Original Strand: ...
... Inversion Mutation: reverse one section of bases (a whole gene) Original Strand: ...
Telomere
A telomere is a region of repetitive nucleotide sequences at each end of a chromatid, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes. Its name is derived from the Greek nouns telos (τέλος) 'end' and merοs (μέρος, root: μερ-) 'part.' For vertebrates, the sequence of nucleotides in telomeres is TTAGGG. This sequence of TTAGGG is repeated approximately 2,500 times in humans. During chromosome replication, the enzymes that duplicate DNA cannot continue their duplication all the way to the end of a chromosome, so in each duplication the end of the chromosome is shortened (this is because the synthesis of Okazaki fragments requires RNA primers attaching ahead on the lagging strand). The telomeres are disposable buffers at the ends of chromosomes which are truncated during cell division; their presence protects the genes before them on the chromosome from being truncated instead.Over time, due to each cell division, the telomere ends become shorter. They are replenished by an enzyme, telomerase reverse transcriptase.