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The Human Genome Project - HudsonAlpha Institute for Biotechnology
The Human Genome Project - HudsonAlpha Institute for Biotechnology

... other and the environment. Furthermore, they didn’t have a clear understanding of how genes keep us healthy or predispose us to disease. A representative genome had been sequenced, but how many differences would be found if peoples from around the world were compared? How did the human sequence comp ...
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Recombinant DNA Technology (b)

... molecule which act as a carrier of the DNA to the host cell. The choice of a vector depends on the design of the experimental system and how the cloned gene will be screened or utilized subsequently. Commonly used vectors are Plasmid, bacteriophage, cosmid, ...
CHAPTER 6: RECOMBINANT DNA TECHNOLOGY
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A Novel Third Isoform of Zebrafish Cytochrome Oxidase IV

... • Analyzing a DNA sequence involves an array of computing tools – Basic Local Alignment Search Tool (BLAST) is offered on the NCBI web site to compare sequences to others, which helps determine function relative to that of other sequences. – Contig express is a software program that allows for the a ...
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Zinc finger nuclease

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms.
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