• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
MB207Jan2010
MB207Jan2010

... uncertain that G1 cells usually prefer to mend their DSBs by NHEJ. or on the -same chromosome if there are duplicate copies of the gene on the chromosome oriented in opposite directions (head-tohead or back-to-back). -Two of the proteins used in homologous recombination are encoded by the genes BRCA ...
Review for Unit 7 Exam
Review for Unit 7 Exam

... A location of their phosphate groups. B nitrogen base that pairs with adenine. C number of oxygen atoms in their sugars. D B and C E A, B, and C 6 The last step in the replication of DNA is catalyzed by A B C D E 7 Which of the A B C D E ...
Nucleic acid
Nucleic acid

... http://highered.mcgraw-hill.com/sites/0072437316/student_view0/chapter14/animations.html# ...
DNA, Transcription, and Translation*.
DNA, Transcription, and Translation*.

... amino acid being put in when the protein is being built; even one wrong amino acid is enough to disrupt the protein’s function ...
DNA Replication
DNA Replication

... exact copy of itself.  Each of the two new cells that will be produced after cell division occurs, will receive one complete set of DNA.  Each strand serves as a template for the building of a new strand  Each original strand produces a new strand of DNA beside itself by complementary base pairin ...
Virtual Mark Recapture Lab
Virtual Mark Recapture Lab

... 4. Which of the following represents the correct order of steps in DNA fingerprinting? a. DNA isolationrestriction enzyme digestiongel electrophoresis b. Restriction enzyme digestiongel electrophoresisDNA isolation c. DNA isolationgel electrophoresisrestriction enzyme digestion d. None of the ...
Recombinant DNA Using Bacterial Plasmids NAME: Background
Recombinant DNA Using Bacterial Plasmids NAME: Background

... 3. Cut the PLASMID (White) strips. Tape the strips in ANY order to make a circular plasmid. 4. As one partner works on step 4, the other partner should cut out the CELL DNA (Non-White) strips. They must be taped together in NUMERICAL ORDER. That is, strip 2 is taped to the bottom of strip 1, and 3 i ...
htt
htt

... the ribosome. The release of the methionine and its addition to the next amino acid occurs, beginning the chain of amino acids that will eventually form the polypeptide. As each tRNA is released, the former one moves to the P site, exposing the A site which allows a new codon to be brought to it. So ...
DNA
DNA

... It is the sequence of bases that determine which protein is to be made. The sequence is like a code that we can now interpret. The sequence determines which proteins are made and the proteins determine which activities will be performed. And that is how the nucleus is the control center of the cell. ...
PP4 (Ch.12-25)DNA
PP4 (Ch.12-25)DNA

... •Anti-parallel to each other •Always builds 5’ to 3’ •DNA Polymerase can only add to the 3’ end If DNA were synthesized in the 3' to 5' direction, the energy for the process would come from the 5' end of the growing strand rather than from free nucleotides. If the 5' nucleotide needed to be removed ...
Meiosis
Meiosis

... shape and that contain genes for the same traits (homologues) • Just like in mitosis, meiosis occurs after interphase, when the cell grows, DNA is replicated, and chromosomes are duplicated. ...
DNA Structure Notes (12.1)
DNA Structure Notes (12.1)

... The DNA Language •DNA carries information in a triplet code. •Each sequence of 3 nucleotides codes for a certain amino acid or for the beginning or end of a sequence. •The genetic code is unique for each organism. ...
GENES are MADE of DNA!
GENES are MADE of DNA!

... The “language” of mRNA instructions is called the genetic code A-U-C-G are the only letters used in the mRNA code the code is read just three letters at a time (like words). Each WORD of the coded message is three bases (letters) long Words are called codons the codons (a group of 3 nucleotides on m ...
Assignment1
Assignment1

... * To see how different algorithms produce different alignments * To try one example of alignment-based database searching * To determine common motif elements within a given set of amino acid or nucleotide sequences. Part 1: Find a pair of DNA sequences that show no significant similarity but are ho ...
The DNA, Replication and Transcription Set
The DNA, Replication and Transcription Set

... in harmful, beneficial, or neutral effects to the structure and function of the organism. • Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. • Ask questio ...
FOSL - Biotechnology Unit Date During class we will… Outside of
FOSL - Biotechnology Unit Date During class we will… Outside of

... HS- LS1-6: Construct and revise an explanation based on evidence for how carbon, hydrogen, and oxygen from sugar molecules may combine with other elements to form amino acids and/or other large carbon-based molecules. HS-LS3-1: Ask questions to clarify relationships about the role of DNA and chromos ...
DNA Structure and Replication
DNA Structure and Replication

... 14. This type of replication is called semi-conservative replication. Considering the meaning of these words (semi—half; conserve—to keep), explain why DNA replication is called semi-conservative. ...
DNA Unit Answers - inetTeacher.com
DNA Unit Answers - inetTeacher.com

... recognize them. Why are they considered ‘frameshift mutations?’ Why are they more disruptive to proteins than a substitution? • Insertion is when an extra letter is put into a DNA strand, and deletion is when a letter is removed. Each three letters of DNA makes an mRNA codon, which codes for a parti ...
Molecular Genetics
Molecular Genetics

... RNA SPLICING • Much of the DNA of an organism does not code for protein. Most genes are interrupted by long segments of nucleotides that have no coding information (kind of like fillers in medications). The noncoding sequences are called introns_ while those that code for amino acids are called ex ...
De novo sample preparation guidelines
De novo sample preparation guidelines

... De novo sample preparation guidelines Genomic DNA for de novo projects IGATech offers nucleic acids extraction (including high molecular weight DNA) service and we can set up a dedicated extraction workflow for your specific substrate. Please enquire. The quality of the DNA sample can have a signifi ...
B. They contain the Homeobox (A unique DNA nucleotide sequence.)
B. They contain the Homeobox (A unique DNA nucleotide sequence.)

... A. The first step in this process uses Restriction Enzymes to create “Sticky Ends” on a plasmid AND DNA from other source. 1. These are enzymes that cut DNA at specific nucleotide sequences. a. This specific DNA sequence is referred to as the Restriction Site. (Fig: 20.3) 2. These enzymes create Res ...
DNA
DNA

... BASES IN THE DNA DETERMINE THE CHARACTERISTIC. BUT SOMETIMES PROBLEMS ARISE…. ...
Slide 1
Slide 1

... chromosome to another or movement from one site to another; does not require homology Transposons: mobile genetic elements that enable genes to move between non-similar sites Retroposition: Creates genetic diversity ...
Replication/mutation
Replication/mutation

... Why is DNA important to your life? • DNA contains information that is critical to the structure and function of your body’s cells – New cells that are made in your body must contain a full set of DNA. – The DNA must be transferred accurately. – The instructions encoded in DNA play a major role in d ...
A1984TV50600002
A1984TV50600002

... binding to DNA. The polycyclic Cation is sandwiched between otherwise adjacent base pairs in the partially unwound helix. The results are stereochemically plausible and conflict with other hypotheses. (The SCI~ indicates that this paperhas been cited in over 950 publications since 1961.] ...
< 1 ... 68 69 70 71 72 73 74 75 76 ... 133 >

Homologous recombination



Homologous recombination is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA. It is most widely used by cells to accurately repair harmful breaks that occur on both strands of DNA, known as double-strand breaks. Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes make gamete cells, like sperm and egg cells in animals. These new combinations of DNA represent genetic variation in offspring, which in turn enables populations to adapt during the course of evolution. Homologous recombination is also used in horizontal gene transfer to exchange genetic material between different strains and species of bacteria and viruses.Although homologous recombination varies widely among different organisms and cell types, most forms involve the same basic steps. After a double-strand break occurs, sections of DNA around the 5' ends of the break are cut away in a process called resection. In the strand invasion step that follows, an overhanging 3' end of the broken DNA molecule then ""invades"" a similar or identical DNA molecule that is not broken. After strand invasion, the further sequence of events may follow either of two main pathways discussed below (see Models); the DSBR (double-strand break repair) pathway or the SDSA (synthesis-dependent strand annealing) pathway. Homologous recombination that occurs during DNA repair tends to result in non-crossover products, in effect restoring the damaged DNA molecule as it existed before the double-strand break.Homologous recombination is conserved across all three domains of life as well as viruses, suggesting that it is a nearly universal biological mechanism. The discovery of genes for homologous recombination in protists—a diverse group of eukaryotic microorganisms—has been interpreted as evidence that meiosis emerged early in the evolution of eukaryotes. Since their dysfunction has been strongly associated with increased susceptibility to several types of cancer, the proteins that facilitate homologous recombination are topics of active research. Homologous recombination is also used in gene targeting, a technique for introducing genetic changes into target organisms. For their development of this technique, Mario Capecchi, Martin Evans and Oliver Smithies were awarded the 2007 Nobel Prize for Physiology or Medicine.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report