lsd lebedev entropy - Spiral
... The dominant approach to psychedelic-assisted therapy involves only one or a small number of high-dose sessions that aim to evoke so-called peak (Maslow, 1964) or mysticaltype experiences (Griffiths et al., 2006; Stace, 1960), characterized by dissolved ego boundaries and a concomitant sense of onen ...
... The dominant approach to psychedelic-assisted therapy involves only one or a small number of high-dose sessions that aim to evoke so-called peak (Maslow, 1964) or mysticaltype experiences (Griffiths et al., 2006; Stace, 1960), characterized by dissolved ego boundaries and a concomitant sense of onen ...
recent advances in animal models of drug addiction
... on reward and reinforcement processes. ICSS differs significantly from drug self-administration in that, in the ICSS procedure, the animal is working to directly stimulate presumed reinforcement circuits in the brain, and the effects of the drugs are assessed on these reward thresholds. Drugs of abu ...
... on reward and reinforcement processes. ICSS differs significantly from drug self-administration in that, in the ICSS procedure, the animal is working to directly stimulate presumed reinforcement circuits in the brain, and the effects of the drugs are assessed on these reward thresholds. Drugs of abu ...
Principles of Pharmacology
... medical providers (EMTs and Paramedics) No portion of this presentation may be reproduced, stored in a retrieval system in any form or by any means (including but not limited to electronic, mechanical, photocopying etc.) without prior written permission from the author ...
... medical providers (EMTs and Paramedics) No portion of this presentation may be reproduced, stored in a retrieval system in any form or by any means (including but not limited to electronic, mechanical, photocopying etc.) without prior written permission from the author ...
Dose-Response Study of N,N-Dimethyltryptamine in Humans
... differentiated clinically from the classical hallucinogens. For example, hallucinogens do not produce general anesthesia at high doses as do PCP or ketamine. Despite limited cogent human psychopharmacologic studies for many years, basic neuropharmacologic work regarding hallucinogens' effects and me ...
... differentiated clinically from the classical hallucinogens. For example, hallucinogens do not produce general anesthesia at high doses as do PCP or ketamine. Despite limited cogent human psychopharmacologic studies for many years, basic neuropharmacologic work regarding hallucinogens' effects and me ...
pharmacokinetics
... through lipid diffusion. The absorption takes place mainly in the upper small intestine. With oral administration of drugs, extensive gastrointestinal and hepatic metabolism may occur before the drugs are absorbed into systemic circulation and reach its site of action. This process is defined as the ...
... through lipid diffusion. The absorption takes place mainly in the upper small intestine. With oral administration of drugs, extensive gastrointestinal and hepatic metabolism may occur before the drugs are absorbed into systemic circulation and reach its site of action. This process is defined as the ...
substance abuse - Nurses Learning Network
... Psychoactive Drugs--A psychoactive drug is a chemical substance that changes one’s thinking, feelings, perceptions, or behaviors. These changes are a result of the drug’s action on the human brain. Many psychoactive drugs already are integrated into the lifestyle of people who daily consume coffee, ...
... Psychoactive Drugs--A psychoactive drug is a chemical substance that changes one’s thinking, feelings, perceptions, or behaviors. These changes are a result of the drug’s action on the human brain. Many psychoactive drugs already are integrated into the lifestyle of people who daily consume coffee, ...
Should neutoleptic drugs be banned ? by Lars Martensson, M.D.
... the two groups of patients. In the year 1980, the average control patient spent over five months in hospital, while the average for Sandin's patients was one month. The limbo-frontal complex. – In addition, there are dopamine receptors in the frontal lobe (prefrontal cortex), although their density ...
... the two groups of patients. In the year 1980, the average control patient spent over five months in hospital, while the average for Sandin's patients was one month. The limbo-frontal complex. – In addition, there are dopamine receptors in the frontal lobe (prefrontal cortex), although their density ...
Antidepressants - Dr BL Lim Centre for Psychological Wellness
... • Also useful in painful somatic symptoms • Examples Duloxetine, Venlaflexine ...
... • Also useful in painful somatic symptoms • Examples Duloxetine, Venlaflexine ...
document
... with morphine and thousands became addicted. Laudanum was widely sold. By the late 1800s, an estimated 4.59 per 1,000 people were dependent on opiates. ...
... with morphine and thousands became addicted. Laudanum was widely sold. By the late 1800s, an estimated 4.59 per 1,000 people were dependent on opiates. ...
From Morphine to Methadone: Maintenance Drugs in The Treatment
... the pain of injuries and chronic illnesses. Their psychoactive properties were also well recognized and exploited to relieve sleep disturbances,anxiety, and depression. These drugs had been known to have these beneficial effects for centuries -in some cases(such as alcohol) for millennia -and they w ...
... the pain of injuries and chronic illnesses. Their psychoactive properties were also well recognized and exploited to relieve sleep disturbances,anxiety, and depression. These drugs had been known to have these beneficial effects for centuries -in some cases(such as alcohol) for millennia -and they w ...
Herbal Medication Pitfalls Question “Natural Product” or Drug
... • Occasional poor science on the part of “experts” leads to product misuse: misidentification; contamination; lack of dose standardization; variability of plant constituents; misrepresentation; product adulteration; and herb-drug and herb-herb interactions… all contribute to safety concerns ...
... • Occasional poor science on the part of “experts” leads to product misuse: misidentification; contamination; lack of dose standardization; variability of plant constituents; misrepresentation; product adulteration; and herb-drug and herb-herb interactions… all contribute to safety concerns ...
new insights into the role of environmental context in the expression
... respect to conditioned sensitization, it has been argued that the environmental context in which the drug is given acts more as an “occasion setter” than as a conventional CS [1]. Similarly, associative accounts of tolerance differ as to whether environmental stimuli elicit a drug-opposite CR [3,6] ...
... respect to conditioned sensitization, it has been argued that the environmental context in which the drug is given acts more as an “occasion setter” than as a conventional CS [1]. Similarly, associative accounts of tolerance differ as to whether environmental stimuli elicit a drug-opposite CR [3,6] ...
The Major Narcotics
... effectiveness Heroin more potent than morphine when injected, but same when taken orally ...
... effectiveness Heroin more potent than morphine when injected, but same when taken orally ...
Late cardiotoxicity
... Q10, or a combination of anti-oxidant vitamins. Other cardioprotective agents such as l-carnitine, probucol, and deferoxamine are being ...
... Q10, or a combination of anti-oxidant vitamins. Other cardioprotective agents such as l-carnitine, probucol, and deferoxamine are being ...
A phase I study of indole-3-carbinol in women
... favoring the development of breast cancer, we have chosen to focus on the first three of these proposed mechanisms. Each can be studied readily by noninvasive means in human subjects. Activities of some carcinogen- and estrogenmetabolizing enzymes can be assessed using a probe drug approach, whereas ...
... favoring the development of breast cancer, we have chosen to focus on the first three of these proposed mechanisms. Each can be studied readily by noninvasive means in human subjects. Activities of some carcinogen- and estrogenmetabolizing enzymes can be assessed using a probe drug approach, whereas ...
here - Michael Rogawski
... sexual maturation (preputial separation, vaginal opening). Hindlimb grip strength was reduced during dosing, but this did not persist in the recovery period. Reproductive performance was not affected. Adverse effects of chronic treatment on learning and memory as assessed by the Cincinnati water maz ...
... sexual maturation (preputial separation, vaginal opening). Hindlimb grip strength was reduced during dosing, but this did not persist in the recovery period. Reproductive performance was not affected. Adverse effects of chronic treatment on learning and memory as assessed by the Cincinnati water maz ...
An Innovative Approach to New Antimicrobial Drugs SUMMARY
... selectivity for the bacterial enzyme over the human one. Although our market research indicates that anticancer drug discovery is not such an attractive market, due to the relative crowding in tha ...
... selectivity for the bacterial enzyme over the human one. Although our market research indicates that anticancer drug discovery is not such an attractive market, due to the relative crowding in tha ...
SSRI`s - Seroxat User Group
... The information presented in Interactions™ is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, case reports, and/or traditional usage with sources as cited in each topic. The results reported may not necessarily oc ...
... The information presented in Interactions™ is for informational and educational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, case reports, and/or traditional usage with sources as cited in each topic. The results reported may not necessarily oc ...
Treatment For Insomnia
... GABAA receptor because of it’s sedative properties similar to other drugs that act at that receptor Can cause some nausea, upset stomach, dizziness, and long-lasting fatigue Is included on the FDA’s Generally Recognized as Safe ...
... GABAA receptor because of it’s sedative properties similar to other drugs that act at that receptor Can cause some nausea, upset stomach, dizziness, and long-lasting fatigue Is included on the FDA’s Generally Recognized as Safe ...
Acetaminophen and Hepatotoxicity
... inactivate the increased amounts of NAPQI, which covalently binds to hepatocyte proteins and leads to cell death. • In addition to enzyme-inducing drugs, other risk factors for paracetamol toxicity have been suggested such as alcoholism and fasting or poor nutritional status. Risk Factors/High Risk ...
... inactivate the increased amounts of NAPQI, which covalently binds to hepatocyte proteins and leads to cell death. • In addition to enzyme-inducing drugs, other risk factors for paracetamol toxicity have been suggested such as alcoholism and fasting or poor nutritional status. Risk Factors/High Risk ...
product info
... side effects of caffeine. At typical dosages, e.g., 100 to 200 mg, L-theanine does not act as a sedative, but it does significantly improve sleep quality. At higher single dosages, e.g., 600 mg, L-theanine does exert a sedative effect. It is an excellent support agent to melatonin and 5-HTP. When th ...
... side effects of caffeine. At typical dosages, e.g., 100 to 200 mg, L-theanine does not act as a sedative, but it does significantly improve sleep quality. At higher single dosages, e.g., 600 mg, L-theanine does exert a sedative effect. It is an excellent support agent to melatonin and 5-HTP. When th ...
32. MaryAnn O Hara et al. A review of 12 commonly used medicinal
... tamoxifen from the Pacific yew tree.4 Unlike the FDA-approved overthe-counter and prescription medications, medicinal herbs are not required to demonstrate either safety or efficacy prior to marketing, nor are they regulated for quality. Nevertheless, herbal therapies are not necessarily less expens ...
... tamoxifen from the Pacific yew tree.4 Unlike the FDA-approved overthe-counter and prescription medications, medicinal herbs are not required to demonstrate either safety or efficacy prior to marketing, nor are they regulated for quality. Nevertheless, herbal therapies are not necessarily less expens ...
The mechanism of action of oral antidiabetic drugs: A review of
... should be very low in patients who have risk factors for heart failure. The concurrent use of these drugs in combination with insulin is not recommended as weight gain can be aggravated.41 Safety of the glitazones in pregnancy and lactation has not yet been established. In some studies, TZDs have de ...
... should be very low in patients who have risk factors for heart failure. The concurrent use of these drugs in combination with insulin is not recommended as weight gain can be aggravated.41 Safety of the glitazones in pregnancy and lactation has not yet been established. In some studies, TZDs have de ...
Clenbuterol - National Drug Strategy
... Most of the above side effects will reduce when clenbuterol is cleared from the body. However, the long-term effects of use on humans are not yet understood. Animal studies have shown that, although clenbuterol has an 'anabolic effect' in rats, there are also some very negative effects on their hear ...
... Most of the above side effects will reduce when clenbuterol is cleared from the body. However, the long-term effects of use on humans are not yet understood. Animal studies have shown that, although clenbuterol has an 'anabolic effect' in rats, there are also some very negative effects on their hear ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.