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GENERIC NAME: nefazodone
GENERIC NAME: nefazodone

... PREGNANCY: There are no adequate studies of nefazodone in pregnant women. Studies in animals have not demonstrated any adverse effects on the developing fetus, but some studies in animals found that the animal offspring were of low weight and died more frequently than those whose mothers were not ex ...
Advanced Toxicology Lecture 3: Excretion
Advanced Toxicology Lecture 3: Excretion

... a. Basis for insult: ↓H+ or ↑HCO3Caused by ingestion of alkaline drugs; excessive vomiting; increase Na+ delivery to distal tubule (increases H+ secretion & loss); low plasma K+; excessive aldosterone. b. Effects and diagnosis: ↑pH and ↑HCO3c. Immediate compensation: high pH slows respiratory drive. ...
NIDA Research Report - Heroin
NIDA Research Report - Heroin

... heroin addiction. Buprenorphine is a recent addition to the array of medications now available for treating addiction to heroin and other opiates. This medication is different from methadone in that it offers less risk of addiction and can be prescribed in the privacy of a doctor’s ...
Energy Drinks - Department of Emergency Medicine
Energy Drinks - Department of Emergency Medicine

... in pill form (ie, Venom Hyperdrive). The simultaneous and excessive use of these products may lead to serious adverse effects. The primary clinical manifestations of caffeine exposure and overdose result from the effects of adrenergic stimulation. In small doses, patients experience the desired effe ...
Asia - INCB
Asia - INCB

... and psychotropic substances to be used for medical purposes is strict, allowing for early detection of drug abuse patterns. Drug law enforcement authorities have been successful in seizing significant quantities of illicitly manufactured drugs entering or passing through Chile. 372. Chile is an impo ...
The incentive sensitization theory of addiction
The incentive sensitization theory of addiction

... Another way of approaching whether incentive sensitization occurs is to ask the question from the brain’s point of view. That is, does sensitization increase neural activations in brain systems that code the incentive value of a reward stimulus? Several studies indicate that it does ( Tindell et al. ...
Labetalol to metoprolol conversion chart
Labetalol to metoprolol conversion chart

... metoprolol succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Calculation of equivalent doses of antihypertensive drugs : β-Blocker. Welcome to Babylon Floral Design, Denver's most unique flower boutiqu ...
NIDA Monograph 169 - pg. 83-104
NIDA Monograph 169 - pg. 83-104

... pharmacological management of anxiety. These drugs are also useful in the emergency room for the treatment of some of the medical compli-cations associated with cocaine intoxication, since convulsions are often apparent following an acute overdose. These seizures can be treated with intravenous (IV) ...
MORPHINE
MORPHINE

... Morphine, like other opiates including Heroin, acts on the central nervous system as an opioid receptor agonist. It binds to and activates the ?-opioid receptors in the central nervous system. Within the brain, the ? -opioid receptors are concentrated in the thalamic, hypothalamic, and amygdalar reg ...
Electronic Structure Based Classification of Neurotransmitters and
Electronic Structure Based Classification of Neurotransmitters and

... neurological or psychiatric symptoms and result in disease. Examples for disorders associated with the defects in neurotransmission are 1) Alzheimer’s disease caused by reduced synthesis of the neurotransmitter acetylcholine; and 2) Parkinson’s disease caused by the insufficient formation and action ...
gabapentin (ga-ba-pen-tin) - DavisPlus
gabapentin (ga-ba-pen-tin) - DavisPlus

... or activities requiring alertness until response to medication is known. Seizure patients should not resume driving until physician gives clearance based on control of seizure disorder. Advise patient and family to notify health care professional if thoughts about suicide or dying, attempts to commi ...
RESET YOUR BODY CORE BOOST // CLEANSE
RESET YOUR BODY CORE BOOST // CLEANSE

...  ilk Thistle extract - Native to Mediterranean regions, milk thistle seeds contain an antioxidant flavonoid complex that stimulates liver enzymes. It is also known to relieve digestive disturbances or indigestion. • Senna extract - Senna is a flowering plant that is used as natural herbal laxative ...
adrenoceptor agonist sympathomimetics
adrenoceptor agonist sympathomimetics

... By the end of this lecture, students should be able to • to describe different classes of anti-platelet drugs depending on their target of action. • To understand pharmacokinetics, pharmacological effects, clinical applications and side effects of anti-platelet drugs. ...
Chapter_021
Chapter_021

... Parkinson’s disease (PD) is a neurodegenerative disorder of the extrapyramidal system associated with disruption of neurotransmission in the striatum ...
Pharmacologic Control of Vomiting
Pharmacologic Control of Vomiting

... of nothing per os may be all that is required), fluid support, and antiemetics. Initial feeding includes small portions of a low fat, single source protein diet starting 6-12 hours after vomiting has ceased. Drugs used to control vomiting will be discussed here. The most effective antiemetics are th ...
ADVERSE REACTIONS - Dentalelle Tutoring
ADVERSE REACTIONS - Dentalelle Tutoring

...  Claims allergies to NSAIDs .  Cancels dental appointment but still requests the opioid analgesic even though they will be “out of town on business”.  Experiences pain for days after scaling and root planing  Moves from office to office because “others don’t understand”.  Claims a “low pain thr ...
Chapter 16 Cholinesterase Inhibitors
Chapter 16 Cholinesterase Inhibitors

... Prevention of acute exacerbations Maintenance of the highest possible level of functioning ...
Clinical and experimental studies on theophylline
Clinical and experimental studies on theophylline

... • Cardiac arrhythmias and seizures not preceded by milder warning symptoms and conventional anti consultants are only partially effective against these seizures • However, in view of its recently demonstrated anti-inflammatory and immunomodulatory effects, it is re-emerging as an important adjunct t ...
mAChR AntagWEB07
mAChR AntagWEB07

... SMOOTH MUSCLE ...
NEUROLEPTICS
NEUROLEPTICS

... Common onset 15-25 years of age 1% general population develops at some point in their lives Common major mental illness in 65+ years Smoking: 3 times more likely in schizophrenia than general population Excessive mortality 20% shorter life expectancy  10% suicide rate ...
GHB - Center for Substance Abuse Research
GHB - Center for Substance Abuse Research

... beverage, usually water or various alcoholic drinks.9 Like other drugs (e.g., ecstasy, marijuana) the chemical composition of GHB is highly variable, and sold in a wide range of concentrations. As a result, there is no definitive way for users to know how strong a particular form of GHB is, thereby ...
SPICE BLEND
SPICE BLEND

... HU-210 to the controlled substance list, effectively making these chemicals illegal • Sweden – JWH-018, JWH-073 and HU-210 were all made illegal in Sweden on 15th of September 2009 • Switzerland – Spice has been banned in Switzerland • U.K. – Spice blends are classified as a medicine in Finland and ...
Anticonvulsive Effect of Seed Extract of Caesalpinia bonducella
Anticonvulsive Effect of Seed Extract of Caesalpinia bonducella

... In traditional system of Indian medicine, C.bonducella is widely used for its antipyretic, antiperiodic, anticonvulsive, and antiparalytic activities. For assessing anticonvulsant activity, pentylenetetrazole, maximal electro shock, strychnine- and picrotoxin-induced convulsions models were used. Di ...
Effects of endocannabinoid neurotransmission modulators on brain
Effects of endocannabinoid neurotransmission modulators on brain

... Furthermore, they may offer a rational approach to various diseases in which elevation of endocannabinoids at their release sites may result in a more selective pharmacological response than the stimulation of CB1 receptors by direct agonists, as mentioned above. This strategy would lead to enhanced ...
Amphetamine-Type Stimulants: A Global Review, 1996
Amphetamine-Type Stimulants: A Global Review, 1996

... and their precursors. Even the category >stimulants=, however, is a very wide one, covering a large range of substances whose principal pharmacological effect is to stimulate the central nervous system of the body. There is some pragmatic justification, detailed in Table 1, in narrowing this categor ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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