Anticholinergic drugs
... Recovery occurs in the reverse sequence: diaphragmatic contractions resume first. Depolarizing agents produce fasciculations , lasting few seconds before inducing flaccid paralysis, but fasciculations are not prominent in well anaesthetized patients. The action of SCh develops very rapidly. Apnoea o ...
... Recovery occurs in the reverse sequence: diaphragmatic contractions resume first. Depolarizing agents produce fasciculations , lasting few seconds before inducing flaccid paralysis, but fasciculations are not prominent in well anaesthetized patients. The action of SCh develops very rapidly. Apnoea o ...
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... Despite some variation in initial dosing, both guidelines advocate for a “start low and go slow” approach, vigilance in assessing signs of toxicity, and slow titrations upward when necessary. ...
... Despite some variation in initial dosing, both guidelines advocate for a “start low and go slow” approach, vigilance in assessing signs of toxicity, and slow titrations upward when necessary. ...
Slide 1
... Recovery occurs in the reverse sequence: diaphragmatic contractions resume first. Depolarizing agents produce fasciculations , lasting few seconds before inducing flaccid paralysis, but fasciculations are not prominent in well anaesthetized patients. The action of SCh develops very rapidly. Apnoea o ...
... Recovery occurs in the reverse sequence: diaphragmatic contractions resume first. Depolarizing agents produce fasciculations , lasting few seconds before inducing flaccid paralysis, but fasciculations are not prominent in well anaesthetized patients. The action of SCh develops very rapidly. Apnoea o ...
Drug Interactions with Tobacco Smoke
... • á Risk of cardiovascular adverse effects (e.g., stroke, myocardial infarction, thromboembolism) in women who smoke and use oral contraceptives. Ortho Evra patch users shown to have 2-fold á risk of venous thromboembolism compared to oral contraceptive users, likely due to á estrogen exposure (60% ...
... • á Risk of cardiovascular adverse effects (e.g., stroke, myocardial infarction, thromboembolism) in women who smoke and use oral contraceptives. Ortho Evra patch users shown to have 2-fold á risk of venous thromboembolism compared to oral contraceptive users, likely due to á estrogen exposure (60% ...
Dr. Amani A. Noory Khartoum, Sudan
... therapeutically – DITIDE (triamterene + benzthiazide) is popular one Modified thiazide: indapamide Indole derivative and long duration of action (18 Hrs) – orally 2.5 mg dose It is a lipid neutral i.e. does not alter blood lipid concentration, but other adverse effects may remain Loop diuret ...
... therapeutically – DITIDE (triamterene + benzthiazide) is popular one Modified thiazide: indapamide Indole derivative and long duration of action (18 Hrs) – orally 2.5 mg dose It is a lipid neutral i.e. does not alter blood lipid concentration, but other adverse effects may remain Loop diuret ...
Hormones in the spotlight
... metabolism, digestion and growth. The application of hormones as growth promoters for foodproducing animals including aquaculture is prohibited in the EU with a strict and limited exceptional use of certain substances for therapeutic uses and livestock breeding. In other countries such as the US, Ca ...
... metabolism, digestion and growth. The application of hormones as growth promoters for foodproducing animals including aquaculture is prohibited in the EU with a strict and limited exceptional use of certain substances for therapeutic uses and livestock breeding. In other countries such as the US, Ca ...
NIDA Research Report - MDMA
... in serotonin metabolites or other markers of serotonin function. Imaging studies in MDMA users have shown changes in brain activity in regions involved in cognition, emotion, and motor function. However, improved imaging technologies and more research are needed to confirm these findings and to eluc ...
... in serotonin metabolites or other markers of serotonin function. Imaging studies in MDMA users have shown changes in brain activity in regions involved in cognition, emotion, and motor function. However, improved imaging technologies and more research are needed to confirm these findings and to eluc ...
Drug Effects on the Fetus and Breast-Fed Infant
... urgent approach. Because of the apparently common misconception of the risks of drug therapy during pregnancy, extra effort may be required to ensure the patient's compliance with the prescribed therapy. This is imperative in maternal conditions in which the disease itself is a greater risk factor f ...
... urgent approach. Because of the apparently common misconception of the risks of drug therapy during pregnancy, extra effort may be required to ensure the patient's compliance with the prescribed therapy. This is imperative in maternal conditions in which the disease itself is a greater risk factor f ...
Antidepressants
... mad as a hatter, blind as a bat Orthostatic hypotension because of α1 Antimuscarinic: avoid with urinary retention, BPH, closed angle glaucoma, increased IOP ...
... mad as a hatter, blind as a bat Orthostatic hypotension because of α1 Antimuscarinic: avoid with urinary retention, BPH, closed angle glaucoma, increased IOP ...
Alkylating Agents
... CNS Depressants Concomitant administration of CNS depressants such as barbiturates, antihistamines, opiates, hypotensive agents, should be undertaken with caution as these drugs may cause potentiation of CNS depression caused by procarbazine. •Other Drugs and Food Patients receiving procarbazine sho ...
... CNS Depressants Concomitant administration of CNS depressants such as barbiturates, antihistamines, opiates, hypotensive agents, should be undertaken with caution as these drugs may cause potentiation of CNS depression caused by procarbazine. •Other Drugs and Food Patients receiving procarbazine sho ...
ANTIGLAUCOMA MEDICATIONS
... • A greater degree of corneal penetration occurs when a higher concentration of nonionized (lipid soluble) drug exists in the instilled drop • Weak bases absorbed through the cornea at a higher pH, while weak acids are absorbed better at a lower pH ...
... • A greater degree of corneal penetration occurs when a higher concentration of nonionized (lipid soluble) drug exists in the instilled drop • Weak bases absorbed through the cornea at a higher pH, while weak acids are absorbed better at a lower pH ...
Sedative–hypnotic and Anxiolytic Drugs
... weak bases, they are less ionized in the relatively alkaline environment of the small intestine, and therefore, most of their absorption takes place at this site. For emergency treatment of seizures or when used in anesthesia, the benzodiazepines also can be given parenterally. Diazepam and lorazepa ...
... weak bases, they are less ionized in the relatively alkaline environment of the small intestine, and therefore, most of their absorption takes place at this site. For emergency treatment of seizures or when used in anesthesia, the benzodiazepines also can be given parenterally. Diazepam and lorazepa ...
Lecture 4, 5- drugs used in bronchial asthma & COPD
... Long acting bronchodilators (12 hours) have high lipid solubility (creates depot effect) are given by inhalation are not used to relieve acute episodes of asthma used for nocturnal asthma (long acting relievers). combined with inhaled corticosteroids to control asthma (decreases the numb ...
... Long acting bronchodilators (12 hours) have high lipid solubility (creates depot effect) are given by inhalation are not used to relieve acute episodes of asthma used for nocturnal asthma (long acting relievers). combined with inhaled corticosteroids to control asthma (decreases the numb ...
THROMBOLYTICS
... With approximately 1.5 million Americans experiencing heart attacks each year, it is easy to see why coronary artery disease is the United States’ number one cause of death. Over half-amillion people will die before they reach the hospital. Thrombolytics were first used in the late 1950’s, but it w ...
... With approximately 1.5 million Americans experiencing heart attacks each year, it is easy to see why coronary artery disease is the United States’ number one cause of death. Over half-amillion people will die before they reach the hospital. Thrombolytics were first used in the late 1950’s, but it w ...
Mixed reviews for a stage-fright remedy
... that they affect only physical, not cognitive, anxiety. "There's very little downside except whatever number you do on yourself about taking the drugs." But now that the drugs have established themselves as a seemingly permanent part of the classical music world, some musicians and physicians are be ...
... that they affect only physical, not cognitive, anxiety. "There's very little downside except whatever number you do on yourself about taking the drugs." But now that the drugs have established themselves as a seemingly permanent part of the classical music world, some musicians and physicians are be ...
Pharmacology 7 – Neuromuscular Blocking Drugs
... » Binds to and excites the postsynaptic nAChR for a long period of time (mins vs msec for ACh) » Eventually action potentials cannot be generated because the voltage sensitive Na channels have been inactivated causing flaccid paralysis Side effects and Pharmacokinetics » Initial spasms due to bindin ...
... » Binds to and excites the postsynaptic nAChR for a long period of time (mins vs msec for ACh) » Eventually action potentials cannot be generated because the voltage sensitive Na channels have been inactivated causing flaccid paralysis Side effects and Pharmacokinetics » Initial spasms due to bindin ...
Basics Pharmacology Review Part 2 - Dr. Halil
... • Earlier Statin + Niacin studies had only showed reduction in soft endpoints. – Eg. Regression of carotid atherosclerosis Rxfiles.ca. AIM-HIGH Trial Summary, Dec 2011. Accessed Apr 29/12. Michael O'Riordan. AIM-HIGH fell short, leaving experts looking for reasons in new review. Heart.org APR 19, 20 ...
... • Earlier Statin + Niacin studies had only showed reduction in soft endpoints. – Eg. Regression of carotid atherosclerosis Rxfiles.ca. AIM-HIGH Trial Summary, Dec 2011. Accessed Apr 29/12. Michael O'Riordan. AIM-HIGH fell short, leaving experts looking for reasons in new review. Heart.org APR 19, 20 ...
Phenobarbital
... • The brain's reward centres normally reinforce behaviours that are good for you, such as eating when you're hungry. • Nicotine hijacks the reward system by attaching to receptors on nerve cells and triggering the release of dopamine, a neurotransmitter which causes pleasant feelings. • Nicotine als ...
... • The brain's reward centres normally reinforce behaviours that are good for you, such as eating when you're hungry. • Nicotine hijacks the reward system by attaching to receptors on nerve cells and triggering the release of dopamine, a neurotransmitter which causes pleasant feelings. • Nicotine als ...
Outline
... o Unknown, bithionol may work may uncoupling oxidative phosphorylation, thus reducing the production of ATP in the helminth ...
... o Unknown, bithionol may work may uncoupling oxidative phosphorylation, thus reducing the production of ATP in the helminth ...
heroin - DrugAbuse.com
... snorted, or dissolved and injected. It is bought and sold on the illicit market as a white or off-white powder and sometimes as a dark, sticky substance known as “black tar heroin.” ...
... snorted, or dissolved and injected. It is bought and sold on the illicit market as a white or off-white powder and sometimes as a dark, sticky substance known as “black tar heroin.” ...
Adverse effects
... •Glucocorticoid replacement therapy may be done by (1) giving the entire daily dose in the morning or (2) splitting the daily dose, giving two-thirds in the morning and onethird in the afternoon. •She asks the nurse if she really has to take pills for this condition for the rest of her life. She ins ...
... •Glucocorticoid replacement therapy may be done by (1) giving the entire daily dose in the morning or (2) splitting the daily dose, giving two-thirds in the morning and onethird in the afternoon. •She asks the nurse if she really has to take pills for this condition for the rest of her life. She ins ...
Corticosteroids_November 2010 FINAL
... Section 4.4 Section 4.4 of the UK SmPC for intranasal products already includes a statement on the risk of systemic side-effects, without specific examples of systemic ADRs. It is proposed to include examples of systemic ADRs to nasal steroids (including psychiatric effects) as a class effect in s ...
... Section 4.4 Section 4.4 of the UK SmPC for intranasal products already includes a statement on the risk of systemic side-effects, without specific examples of systemic ADRs. It is proposed to include examples of systemic ADRs to nasal steroids (including psychiatric effects) as a class effect in s ...
Relative Reinforcing Effects of Cocaine, Remifentanil, and Their
... function of percentage of drug choice over food, rate of responding, and total reinforcers. The majority of these studies indicate that combining a stimulant and an opioid does not result in a stimulus with an enhanced reinforcing effectiveness. The following study was designed to ask this question ...
... function of percentage of drug choice over food, rate of responding, and total reinforcers. The majority of these studies indicate that combining a stimulant and an opioid does not result in a stimulus with an enhanced reinforcing effectiveness. The following study was designed to ask this question ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.