Synthetic Drugs of Abuse
... opioid receptors, with mitragynine having an effect at alpha-adrenergic receptors in lower doses. • The drug has limited effect on respiratory drive, making it relatively safe in pure form. • Kratom is often used in Southeast Asia to mediate the severity of heroin withdrawal. ...
... opioid receptors, with mitragynine having an effect at alpha-adrenergic receptors in lower doses. • The drug has limited effect on respiratory drive, making it relatively safe in pure form. • Kratom is often used in Southeast Asia to mediate the severity of heroin withdrawal. ...
PPT - International Neurourology Journal
... intravesical drug instillation is considered an unmet clinical need for the treatment of bladder diseases. • To resolve this, implantable devices enabled with sustained intravesical drug delivery have been studied. • For easy insertion via the urinary tract, the devices are designed to be mostly tub ...
... intravesical drug instillation is considered an unmet clinical need for the treatment of bladder diseases. • To resolve this, implantable devices enabled with sustained intravesical drug delivery have been studied. • For easy insertion via the urinary tract, the devices are designed to be mostly tub ...
Slide 1
... The drug metabolite may be: Inactive: metabolism results in termination of drug action e.g. most drugs. Active like the parent drug: e.g. diazepam (sedative and hypnotic). Active and the parent drug is inactive: (prodrug) e.g. methotrexate ...
... The drug metabolite may be: Inactive: metabolism results in termination of drug action e.g. most drugs. Active like the parent drug: e.g. diazepam (sedative and hypnotic). Active and the parent drug is inactive: (prodrug) e.g. methotrexate ...
7.4 Drugs as Amines
... Many drugs (probably 85% of the drugs on the market) contain amine groups covalently bonded to groups that are relatively hydrophobic. Most of these drugs are administered in the ammonium ion form. This accomplishes two objectives. 1) It makes the drug more water soluble (very important if the drug ...
... Many drugs (probably 85% of the drugs on the market) contain amine groups covalently bonded to groups that are relatively hydrophobic. Most of these drugs are administered in the ammonium ion form. This accomplishes two objectives. 1) It makes the drug more water soluble (very important if the drug ...
Neurobiology of Addiction and Recovery
... The highest risk of relapse for cocaine addicts is during the third and fourth week of abstinence. PET images show even lower levels of activity in the mesolimbic dopamine system during this time. The addict is almost back to normal after a year or so, but not completely. ...
... The highest risk of relapse for cocaine addicts is during the third and fourth week of abstinence. PET images show even lower levels of activity in the mesolimbic dopamine system during this time. The addict is almost back to normal after a year or so, but not completely. ...
Analgesics Power Point - IHMC Public Cmaps (3)
... • Cross-tolerance is the condition where tolerance for one drug produces tolerance for another drug – person who is tolerant to morphine will also be tolerant to the analgesic effect of fentanyl, heroin, and other opioids • * note that a subject may be physically dependent on heroin can also be admi ...
... • Cross-tolerance is the condition where tolerance for one drug produces tolerance for another drug – person who is tolerant to morphine will also be tolerant to the analgesic effect of fentanyl, heroin, and other opioids • * note that a subject may be physically dependent on heroin can also be admi ...
Open poster - CTN Dissemination Library
... combined with naloxone in a 4:1 ratio to lower its abuse potential, has been effective for detoxification and maintenance treatment. Research suggests that dosing levels in opioid dependence treatment are associated with patient-related factors: race, psychiatric symptoms, gender, and, potentially, ...
... combined with naloxone in a 4:1 ratio to lower its abuse potential, has been effective for detoxification and maintenance treatment. Research suggests that dosing levels in opioid dependence treatment are associated with patient-related factors: race, psychiatric symptoms, gender, and, potentially, ...
OPIOID ANALGESICS
... • Cross-tolerance is the condition where tolerance for one drug produces tolerance for another drug – person who is tolerant to morphine will also be tolerant to the analgesic effect of fentanyl, heroin, and other opioids • * note that a subject may be physically dependent on heroin can also be admi ...
... • Cross-tolerance is the condition where tolerance for one drug produces tolerance for another drug – person who is tolerant to morphine will also be tolerant to the analgesic effect of fentanyl, heroin, and other opioids • * note that a subject may be physically dependent on heroin can also be admi ...
factors modifying drug dose-response relationship
... –X. Proven risk of fetal harm- Drugs should not be used –Pregnant women should avoid drugs completely –If PG woman has been exposed: Find out exactly when drug was taken– if not during weeks 2-8 then patient should be reassured that risk of malformation is minimal & 3% of all babies have some kind o ...
... –X. Proven risk of fetal harm- Drugs should not be used –Pregnant women should avoid drugs completely –If PG woman has been exposed: Find out exactly when drug was taken– if not during weeks 2-8 then patient should be reassured that risk of malformation is minimal & 3% of all babies have some kind o ...
8-Anti-mycobacterial drugs
... Clofazimine is a phenazine dye with Antimycobacterial and Antiinflammatory effect. Clofazimine is bactericidal against M. tuberculosis, is bacteriostatic against M. leprae, and is active against M. avium intracellulare. The drug enhances the phagocytic activity of Neutrophils and Macrophages, and re ...
... Clofazimine is a phenazine dye with Antimycobacterial and Antiinflammatory effect. Clofazimine is bactericidal against M. tuberculosis, is bacteriostatic against M. leprae, and is active against M. avium intracellulare. The drug enhances the phagocytic activity of Neutrophils and Macrophages, and re ...
Mood Stabilisers
... Cyclic adenosine monophosphate (cAMP) intracellular signal transduction A different process of neurotransmission ...
... Cyclic adenosine monophosphate (cAMP) intracellular signal transduction A different process of neurotransmission ...
Healing Pointstm - Richard Grossman
... He added that individuals who are feeling sick should not delay making phone calls or seeking care until the weekend. “A clear implication of our study is that high-quality medical care can save a patient's life,” Redelmeier said. The findings support the results of previous studies. The rate of dea ...
... He added that individuals who are feeling sick should not delay making phone calls or seeking care until the weekend. “A clear implication of our study is that high-quality medical care can save a patient's life,” Redelmeier said. The findings support the results of previous studies. The rate of dea ...
April 2016 - Academy of Art University
... The Academy of Art University will reasonably accommodate any employee, faculty, or students who volunteers to enter an alcohol or drug rehabilitation programs, provided the reasonable accommodation does not impose undue hardship on the Academy of Art University. Reasonable accommodation could inclu ...
... The Academy of Art University will reasonably accommodate any employee, faculty, or students who volunteers to enter an alcohol or drug rehabilitation programs, provided the reasonable accommodation does not impose undue hardship on the Academy of Art University. Reasonable accommodation could inclu ...
presentation source
... • Reduction in fertility • Crosses placental barrier -correlated to cognitive/behavioral problems in children ...
... • Reduction in fertility • Crosses placental barrier -correlated to cognitive/behavioral problems in children ...
L6- Teratogens and drugs of abuse
... All antiepileptics have potential to cause malformations, carbamazepine may be choice. avoid valproic acid (highly teratogenic). folic acid supplementation prevents neural tube defects in women receiving AEDs ...
... All antiepileptics have potential to cause malformations, carbamazepine may be choice. avoid valproic acid (highly teratogenic). folic acid supplementation prevents neural tube defects in women receiving AEDs ...
UnityPoint Health PowerPoint Template
... • Mom is on methadone maintenance for a previous heroin addiction • You meet a well dressed young woman who is obviously nervous about this discussion • Her main question: Can I breastfeed? ...
... • Mom is on methadone maintenance for a previous heroin addiction • You meet a well dressed young woman who is obviously nervous about this discussion • Her main question: Can I breastfeed? ...
Teacher Notes
... How alcohol education is taught is important Early adolescence has been identified as a critical inoculation period in students’ behavioural development when the intervention effects of alcohol education are most likely to be optimised. It is at this age that most students will have experienced some ...
... How alcohol education is taught is important Early adolescence has been identified as a critical inoculation period in students’ behavioural development when the intervention effects of alcohol education are most likely to be optimised. It is at this age that most students will have experienced some ...
Oral laquinimod therapy in relapsing multiple sclerosis Drug Evaluation Jana Preiningerova
... Most patients with relapsing forms of MS benefit from interferon beta or glatiramer acetate injections by gaining partial control over the disease activity as measured by relapse rate, number of gadolinium (Gd) enhancing lesions on brain magnetic resonance imaging (MRI) and accumulation of lesions o ...
... Most patients with relapsing forms of MS benefit from interferon beta or glatiramer acetate injections by gaining partial control over the disease activity as measured by relapse rate, number of gadolinium (Gd) enhancing lesions on brain magnetic resonance imaging (MRI) and accumulation of lesions o ...
Pharmacodynamics
... • The benefit-risk balance of a drug must be positive in order to gain and maintain product approval. • Benefits are commonly expressed as the proven therapeutic good of a product, but should also include the patient’s subjective assessment of its effects • Risk is the probability of harm being caus ...
... • The benefit-risk balance of a drug must be positive in order to gain and maintain product approval. • Benefits are commonly expressed as the proven therapeutic good of a product, but should also include the patient’s subjective assessment of its effects • Risk is the probability of harm being caus ...
Snímek 1
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
Snímek 1
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
... Ultrarapid metabolizers may break down some drugs (e.g. some antidepressants) so quickly that the drug does not need to help at usual doses. They may also need a lower dose of a drug, in the case where a drug is metabolized in active metabolites (e.g. in some opioid analgesics) Poor metabolizers hav ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.