IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... Drugs increase the volume or decrease the viscosity of respiratory secretions, facilitate their removal by ciliary action and coughing. 1.1Mucolytic expectorants: Drugs alter chemical characteristics of sputum to decrease its viscosity and to facilitate its removal by ciliary action or coughing. eg. ...
... Drugs increase the volume or decrease the viscosity of respiratory secretions, facilitate their removal by ciliary action and coughing. 1.1Mucolytic expectorants: Drugs alter chemical characteristics of sputum to decrease its viscosity and to facilitate its removal by ciliary action or coughing. eg. ...
The role of drug metabolism in drug discovery and
... University of Oulu, P.O. Box 8000, FI-90014 University of Oulu, Finland ...
... University of Oulu, P.O. Box 8000, FI-90014 University of Oulu, Finland ...
annex iv: biowaiver request for additional strengths
... bioavailabilities in terms of peak (Cmax and Tmax) and total exposure (AUC) after administration of the same molar dose under the same conditions are similar to such a degree that their effects with respect to both efficacy and safety can be expected to be essentially the same. Bioequivalence focuse ...
... bioavailabilities in terms of peak (Cmax and Tmax) and total exposure (AUC) after administration of the same molar dose under the same conditions are similar to such a degree that their effects with respect to both efficacy and safety can be expected to be essentially the same. Bioequivalence focuse ...
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... and Tajikistan) are based on partial national data only and should be interpreted with caution. The prevalence of MDR-TB among new cases was f4% in all EU/EEA countries, except for the Baltic states, where this prevalence ranged from 11.1% in Lithuania to 22.9% in Estonia. Owing to limited DST to se ...
... and Tajikistan) are based on partial national data only and should be interpreted with caution. The prevalence of MDR-TB among new cases was f4% in all EU/EEA countries, except for the Baltic states, where this prevalence ranged from 11.1% in Lithuania to 22.9% in Estonia. Owing to limited DST to se ...
Charles University in Prague Faculty of Pharmacy in Hradec Králové
... transformations involve reactions that introduce or unmask a functional group, such as oxygenation or hydrolysis. Phase II transformations mostly generate highly polar derivatives, such as glucuronides and sulphate esters, for excretion in the urine. Phenolic drugs are often subjected to phase II me ...
... transformations involve reactions that introduce or unmask a functional group, such as oxygenation or hydrolysis. Phase II transformations mostly generate highly polar derivatives, such as glucuronides and sulphate esters, for excretion in the urine. Phenolic drugs are often subjected to phase II me ...
Cobicistat / Tenofovir disoproxil fumarate / Emtricitabine / Elvitegravir
... The product is referred to as ‘Stribild’ throughout this document; however, the names ‘Quad’ and ‘Stribild’ are considered interchangeable for the purpose of this AusPAR. The proposed formulation is described as a single-tablet regimen (STR) and contains 2 new chemical entities, EVG and COBI, which ...
... The product is referred to as ‘Stribild’ throughout this document; however, the names ‘Quad’ and ‘Stribild’ are considered interchangeable for the purpose of this AusPAR. The proposed formulation is described as a single-tablet regimen (STR) and contains 2 new chemical entities, EVG and COBI, which ...
Nancy Caroline`s Emergency Care in the Streets, Seventh Edition
... in relation to patient care. • Cultural considerations: Traditional medicines such as those found in Asia have gained popularity throughout the world. It is prudent for paramedics to inquire about all medications and preparations, not just those filled through a pharmacy. ...
... in relation to patient care. • Cultural considerations: Traditional medicines such as those found in Asia have gained popularity throughout the world. It is prudent for paramedics to inquire about all medications and preparations, not just those filled through a pharmacy. ...
Migraine — Current Understanding and Treatment
... opiates, and combination analgesics, are used to treat a wide range of pain disorders. Specific treatments,7 including ergotamine, dihydroergotamine, and the triptans, are effective for treating neurovascular headaches, such as migraine and cluster headache, but not for treating other types of pain, ...
... opiates, and combination analgesics, are used to treat a wide range of pain disorders. Specific treatments,7 including ergotamine, dihydroergotamine, and the triptans, are effective for treating neurovascular headaches, such as migraine and cluster headache, but not for treating other types of pain, ...
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... and Tajikistan) are based on partial national data only and should be interpreted with caution. The prevalence of MDR-TB among new cases was f4% in all EU/EEA countries, except for the Baltic states, where this prevalence ranged from 11.1% in Lithuania to 22.9% in Estonia. Owing to limited DST to se ...
... and Tajikistan) are based on partial national data only and should be interpreted with caution. The prevalence of MDR-TB among new cases was f4% in all EU/EEA countries, except for the Baltic states, where this prevalence ranged from 11.1% in Lithuania to 22.9% in Estonia. Owing to limited DST to se ...
Comparison of the effects of cimetidine and hyoscine-n
... motility and hence its effect on the absorption of other orally co-administered drugs cannot be attributed to a possible effect on gastric motility [5,6,7]. However, Garba et al [8] had previously postulated an additional mechanism for Cimetidine- drug interactions, suggesting that in addition to th ...
... motility and hence its effect on the absorption of other orally co-administered drugs cannot be attributed to a possible effect on gastric motility [5,6,7]. However, Garba et al [8] had previously postulated an additional mechanism for Cimetidine- drug interactions, suggesting that in addition to th ...
How Criminal Law Affects Health Care and Religious Freedom
... hallucinatory effect than even drugs like marijuana and mushrooms. Since Salvia can be easily grown as a houseplant and distributed in smoke shops or online in psychedelic colored packaging, legislators moved swiftly once Salvia sprang into the public’s eye. Canada plans to outlaw Salvia nationally, ...
... hallucinatory effect than even drugs like marijuana and mushrooms. Since Salvia can be easily grown as a houseplant and distributed in smoke shops or online in psychedelic colored packaging, legislators moved swiftly once Salvia sprang into the public’s eye. Canada plans to outlaw Salvia nationally, ...
Collagenase clostridium histolyticum
... This AusPAR describes the submission by Actelion Pharmaceuticals Australia Pty Ltd to register a new biological entity, collagenase clostridium histolyticum, for the treatment of Dupuytren’s contracture in adult patients with palpable cord. Dupuytren’s contracture is a relatively common disorder in ...
... This AusPAR describes the submission by Actelion Pharmaceuticals Australia Pty Ltd to register a new biological entity, collagenase clostridium histolyticum, for the treatment of Dupuytren’s contracture in adult patients with palpable cord. Dupuytren’s contracture is a relatively common disorder in ...
Benzoyl Peroxide Cleansers for the Treatment of Acne Vulgaris: Status D
... It is well-documented that over time the prevalence of P acnes strains that are less sensitive to commonly prescribed antibiotics for the treatment of acne vulgaris such as tetracyclines, erythromycin, and clindamycin has increased. 1,2,13-19 The clinical significance of these antibiotic-resistant s ...
... It is well-documented that over time the prevalence of P acnes strains that are less sensitive to commonly prescribed antibiotics for the treatment of acne vulgaris such as tetracyclines, erythromycin, and clindamycin has increased. 1,2,13-19 The clinical significance of these antibiotic-resistant s ...
drug information - NurseCe4Less.com
... and treatments for the diseases and medical conditions that had previously been not possible to cure. These are due to advancements in pharmacology - the study of actions of drugs on living organisms. The medical staff including doctors, nurses and clinicians don’t only need to be aware of older med ...
... and treatments for the diseases and medical conditions that had previously been not possible to cure. These are due to advancements in pharmacology - the study of actions of drugs on living organisms. The medical staff including doctors, nurses and clinicians don’t only need to be aware of older med ...
Emerging options for the management of scorpion stings
... syndrome, the latter occurring mostly in children during viral infections treated by salicylates.37 The incidence of Reye’s syndrome, the symptoms of which can be confused with worsening of envenoming, is low at about 0.8 cases per million children,38 but is often fatal. Therefore, it is necessary t ...
... syndrome, the latter occurring mostly in children during viral infections treated by salicylates.37 The incidence of Reye’s syndrome, the symptoms of which can be confused with worsening of envenoming, is low at about 0.8 cases per million children,38 but is often fatal. Therefore, it is necessary t ...
Impact of levalbuterol versus Albuterol in Kentucky Medicaid Patients
... treatment of asthma. Racemic albuterol has been used for more than 40 years but is associated with several side effects including tremor. When levalbuterol was approved in 2005 its manufacturer and several studies suggested that using levalbuterol results in better respiratory parameters, fewer hosp ...
... treatment of asthma. Racemic albuterol has been used for more than 40 years but is associated with several side effects including tremor. When levalbuterol was approved in 2005 its manufacturer and several studies suggested that using levalbuterol results in better respiratory parameters, fewer hosp ...
500ct. 10-325 mg HCb and APAP Tablets[Watson[Base[rev2
... Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen containing ...
... Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen containing ...
November 2015 – Positive Recommendations (Word 80KB)
... alafenamide (EVG/c/FTC/tenofovir alafenamide) fixed dose combination for the treatment of HIV. The PBAC recommended the special arrangements under the HSD Community Access, Authority Required (STREAMLINED). The PBAC recommended the listing of EVG/c/FTC/tenofovir alafenamide on a cost-minimisation ba ...
... alafenamide (EVG/c/FTC/tenofovir alafenamide) fixed dose combination for the treatment of HIV. The PBAC recommended the special arrangements under the HSD Community Access, Authority Required (STREAMLINED). The PBAC recommended the listing of EVG/c/FTC/tenofovir alafenamide on a cost-minimisation ba ...
Safe Handling of Hazardous Drugs
... updated as new information becomes available. Importantly, new drugs should routinely undergo a hazard assessment. Periodic updates to the NIOSH list can be found at: http://www.cdc.gov/niosh/topics/hazdrug/. ...
... updated as new information becomes available. Importantly, new drugs should routinely undergo a hazard assessment. Periodic updates to the NIOSH list can be found at: http://www.cdc.gov/niosh/topics/hazdrug/. ...
AusPAR: Sevelamer hydrochloride
... Sevelamer hydrochloride is not systemically absorbed and consequently no biopharmaceutic studies were provided with the submission. Neither have clinical equivalence studies comparing the proposed and innovator products been conducted. Rather, studies were conducted in which the in vitro phosphate b ...
... Sevelamer hydrochloride is not systemically absorbed and consequently no biopharmaceutic studies were provided with the submission. Neither have clinical equivalence studies comparing the proposed and innovator products been conducted. Rather, studies were conducted in which the in vitro phosphate b ...
DOPamine Hydrochloride and 5% Dextrose Injection, USP
... half-life of about two minutes, the duration of action is less than ten minutes. If monoamine oxidase (MAO) inhibitors are present, however, the duration may increase to one hour. The drug is widely distributed in the body but does not cross the blood-brain barrier to a significant extent. Dopamine ...
... half-life of about two minutes, the duration of action is less than ten minutes. If monoamine oxidase (MAO) inhibitors are present, however, the duration may increase to one hour. The drug is widely distributed in the body but does not cross the blood-brain barrier to a significant extent. Dopamine ...
July 2016 PBAC Meeting
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
The Socio-Economic Impact of Amphetamine Type Stimulants in
... This preparation of this report was funded by the New Zealand Police with money received from the Cross Departmental Research Pool (CDRP), which is administered by the Ministry of Research Science and Technology (MoRST). We acknowledge the assistance and collaborative efforts of officials from the O ...
... This preparation of this report was funded by the New Zealand Police with money received from the Cross Departmental Research Pool (CDRP), which is administered by the Ministry of Research Science and Technology (MoRST). We acknowledge the assistance and collaborative efforts of officials from the O ...
March 2017 PBAC Meeting Agenda (Word 67KB)
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
... Consumers will have the opportunity to provide comments on new drug submissions (item 5), changes to listings (item 6) and resubmissions (item 7). In many circumstances, consumers will be able to comment on items in other sections of the agenda. The submissions for which input is sought will be list ...
Polysubstance dependence
A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.