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COLONIC DRUG DELIVERY SYSTEM OF TRIMETAZIDINE HYDROCHLORIDE FOR ANGINA  PECTORIS    Research Article 
COLONIC DRUG DELIVERY SYSTEM OF TRIMETAZIDINE HYDROCHLORIDE FOR ANGINA  PECTORIS    Research Article 

Medication errors related to transdermal opioid reporting system
Medication errors related to transdermal opioid reporting system

... in our study was categorized as wrong dose – high; a patient who was treated with a relatively high dose, 250 μg, was discovered to have two sets of patches of the prescribed dose on his body at the same time. This most likely contributed to his symptoms that caused admission. Both accidental and vo ...
Impact of drug importation on community pharmacy and patient care
Impact of drug importation on community pharmacy and patient care

... the lower acquisition costs. Some have proposed that Americans should be able to get all or a major share of their medications from Canada. The problem with this scenario is that Canada does not have the drug supply to meet the needs of Canadians and a large contingent of the U.S. population. Based ...
submission
submission

... noted that there was an increase in the level of a protein called insulin-like growth factor 1 (IGF-1) in a considerable number of patients treated with tesamorelin (EMA website, 2013). High levels of IGF-1 may be associated with an increased risk of cancer and a potential worsening of diabetic eye ...
tablet (ODT) - Rajiv Gandhi University of Health Sciences
tablet (ODT) - Rajiv Gandhi University of Health Sciences

... good taste and disintegrated in the oral cavity within 30s. One important innovation in this direction is the development of fast dissolving/disintegrating oral dosage forms that dissolve or disintegrate instantly upon contact with recipient's tongue or buccal mucosa. They have proved to be ideal fo ...
Prehospital Pharmacology
Prehospital Pharmacology

... • Because of this, babies and young children should be approached with a higher index of ...
Overdose Emergency Procedures and Narcan
Overdose Emergency Procedures and Narcan

... Myth #1: If you give an overdose antidote to drug users, they will abuse more drugs Fact: Studies report that naloxone does not encourage drug use, and in fact, has been shown to decrease it in some circumstances. By blocking the effects of opiates, naloxone can produce unpleasant withdrawal symptom ...
CHEMICAL STABILITY STUDIES OF BIOADHESIVE TOPICAL GEL  Research Article LALIT KUMAR
CHEMICAL STABILITY STUDIES OF BIOADHESIVE TOPICAL GEL  Research Article LALIT KUMAR

cocaine 68, 111, 145, 150, 164, 192, 201, 208, 209, 226, 270, 274
cocaine 68, 111, 145, 150, 164, 192, 201, 208, 209, 226, 270, 274

... information processing in the first year of life. In a prospective, longitudinal study of 177 cocaine-exposed and 175 non-exposed infants, the Fagan Test of Infant Intelligence (FTII) was used to measure attention, visual recognition memory and information processing speed at 6.5 and 12 months of ag ...
US FDA Drug Approval Strategies for Pharmaceutical Industry
US FDA Drug Approval Strategies for Pharmaceutical Industry

... In Pharmaceutical Industry, Regulatory Affairs Department makes an interface between the regulatory authorities and pharmaceutical industry. The Regulatory Affairs department is an important part of the organizational structure of pharmaceutical companies. Internally it liaises at the inter phase of ...
Product Name: Ibuprofen Oral Suspension 100mg/5mL
Product Name: Ibuprofen Oral Suspension 100mg/5mL

... 1ug/mL did not demonstrate ibuprofen in the milk of lactating mothers. Because of the limited nature of these studies, however, and the possible adverse effects of prostaglandin inhibiting drugs on newborns, this drug is not recommended for use in nursing mothers. The safety and effectiveness in ped ...
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(part 1)

...  If the concentration of medicinal substance was`t noted in a recipe, it is followed to prepare 10 % ointment.  Ointments the samples of which are standardized. prepare according to concentration of medicinal substances, marked in NTD.  Introductions of medicinal substances in ointment conduct ta ...
The Abuse of Anabolic Androgenic Steroids  and Other Hormonal Drugs
The Abuse of Anabolic Androgenic Steroids and Other Hormonal Drugs

... attention is sought in primary care and other clinics. In order to better understand individuals seeking treatment for these problems, and offer them adequate treatment, it is essential to detect the underlying abuse. This document offers some concrete examples of physical, mental, and laboratory-ba ...
Buprenorphine for Pain and for Addiction
Buprenorphine for Pain and for Addiction

... DSM IV Substance Dependence A maladaptive pattern of substance use, with 3 or more of: • Tolerance • Withdrawal • Using larger amounts or for a longer time than intended • Persistent desire or lack of control • A great deal of time spent obtaining, using, recovering from • Important activities give ...
Product Monograph Template - Standard
Product Monograph Template - Standard

... neonatal body weight, increased neonatal mortality, and developmental delays at 48 mg/kg (see TOXICOLOGY). Geriatrics (> 65 years of age): Of the total number of subjects in clinical studies of ULORIC®, 16% were 65 and over, while 4% were 75 and over. Comparing subjects in different age groups, no c ...
6 - cazacu - safety.indd
6 - cazacu - safety.indd

... an over-the-counter drug during pregnancy. In a study monitoring 197 pregnant women with 1st trimester exposure to guaifenesin, an increase in the expected frequency of inguinal hernias was found. For the use in any trimester of pregnancy, no malformations were observed [1]. Guaifenesin use in pregn ...
Where to purchase Diane no rx
Where to purchase Diane no rx

... Where to purchase Diane no rx The depressive disorder of the patients studied patients with end-stage renal failure. And Suicidal Thoughts or Actions, Quitting Smoking, children and adolescents with MDD, obsessive compulsive 2-fold higher in patients with impaired renal with and should counsel them ...
Inheritance and Drug Response - New England Journal of Medicine
Inheritance and Drug Response - New England Journal of Medicine

... the antineoplastic agent fluorouracil. In the mid1980s, fatal central nervous system toxicity developed in several patients after treatment with standard doses of fluorouracil.39,40 The patients were shown to have an inherited deficiency of dihydropyrimidine dehydrogenase, an enzyme that metabolizes ...
Buprenorphine for Pain and for Addiction
Buprenorphine for Pain and for Addiction

... DSM IV Substance Dependence A maladaptive pattern of substance use, with 3 or more of: • Tolerance • Withdrawal • Using larger amounts or for a longer time than intended • Persistent desire or lack of control • A great deal of time spent obtaining, using, recovering from • Important activities give ...
sult4a1-1 positive - PGXL Laboratories
sult4a1-1 positive - PGXL Laboratories

... • 23 million Americans take prescription medications for depression • 253 million prescriptions in 2010 • Prescribers have no way of knowing which class of drugs or which dose will work for the patient • 63% of patients fail first-line therapy • 16.3% stop taking medication altogether due to drug in ...
A Scientific Perspective on Marijuana on the Eve of Its
A Scientific Perspective on Marijuana on the Eve of Its

... hundreds to thousands of biologically active compounds. Though there are only three species of the cannabis plant, there are vast numbers of strains, varieties, and hybrids that are in continuous development, each with varying levels of different molecules and compounds that the marijuana plant prod ...
Product Monograph - Paladin Labs Inc.
Product Monograph - Paladin Labs Inc.

... either methylphenidate or non-medication treatment groups over 14 months, as well as in naturalistic subgroups of newly methylphenidate-treated and non-medication treated children over 36 months (to the ages of 10 to 13 years), suggests that consistently medicated children (i.e., treatment for 7 day ...
HEPATOPROTECTIVE ACTIVITY OF AN ETHANOLIC EXTRACT OF STEMS OF ANISOCHILUS  CARNOSUS AGAINST CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY IN RATS 
HEPATOPROTECTIVE ACTIVITY OF AN ETHANOLIC EXTRACT OF STEMS OF ANISOCHILUS  CARNOSUS AGAINST CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY IN RATS 

Antipsychotics for the treatment of OCD in children and
Antipsychotics for the treatment of OCD in children and

... The SCG recognises there are differences in commissioning of Child and Adolescent Mental Health Services across the Trust for 16 to 18 year olds and that there are differences in the practice of prescribing and supervision for 16 to 18 year olds by working age adult psychiatrists. Obsessive compulsi ...
Dementia prescribing: Good practice guidance
Dementia prescribing: Good practice guidance

... An ECG should be taken prior to commencing treatment. Prescribing must take place in the approved memory service. Consider the circumstances of the service user when choosing an AChEl. If there are no individual considerations or contraindications choose donepezil. Use once a day oral preparation wh ...
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Polysubstance dependence



A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.
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