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Niosome and Proniosome – Vesicular Structured Dosage Form for
Niosome and Proniosome – Vesicular Structured Dosage Form for

... Drug targeting is a specific form of drug delivery where the pharmacological agent is directed selectively to its site of action or absorption. The specific site may be a particular organ, structure, cell or an intracellular region. Targeted drug delivery is a method of delivering medication to a pa ...
Fabrication of Bucco-matrix tablets of Amoxicillin trihydrate on the
Fabrication of Bucco-matrix tablets of Amoxicillin trihydrate on the

... delivery systems (Gafourian et al., 2007). HPMCK100M and HPMCK15M along with Carbopol 934p have been selected here. To get controlled release through the use of HPMC like polymers, it generally gets hydrated on the surface to form a gelatinous layer. This gelatinous layer prevents entry of water to ...
Popular Depression Medications
Popular Depression Medications

... Imipramine is an antidepressant medication of the tricyclic class. Medications in this class are often referred to as tricyclic antidepressants or TCAs. Depression is defined as an all-pervasive sense of sadness and gloom. In patients with depression, abnormal levels of chemicals in the brain (calle ...
MS_Word ~ 184 KB
MS_Word ~ 184 KB

... When required, access must be in accordance with procedures approved by the Drug and Therapeutics Committee and restricted to delegated senior nursing and/or medical staff. Where additional access controls are deemed appropriate, local protocols approved by the director of pharmacy and the Drug and ...
COX 2 Inhibitors: New Non-Steroidal Anti
COX 2 Inhibitors: New Non-Steroidal Anti

... increased by the supratherapeutic dosages used in the study or as a result of the high number of patients taking low-dose aspirin concommitantly. Low-dose aspirin appears to have offset any potential protective effect of COX-2 selectivity for celecoxib in this trial. The results of this study provid ...
Pharmacology
Pharmacology

... (D) Viruses (4) Pharmacokinetics is the way by which the body deal with: (A) Drugs (B) Mouth (C) Kidney (D) Stomach (5) Pharmacokinetics include the following: (A) Absorption & Metabolism & Distribution & Excretion (B) Absorption only (C) Distribution only (D) Metabolism only (6) Pharmacodynamic is ...
What CATIE Found: Results From the Schizophrenia Trial
What CATIE Found: Results From the Schizophrenia Trial

... The authors provide an overview of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) sponsored by the National Institute of Mental Health. CATIE was designed to compare a proxy first-generation antipsychotic, perphenazine, to several newer drugs. In phase 1 of the trial, consen ...
Depression - Michigan Medicine
Depression - Michigan Medicine

... Depression is a common disease with substantial morbidity and mortality. Approximately 5% of the population has major depression at any given time, with men experiencing a lifetime risk of 7-12%; and women 20-25%. The direct and indirect costs associated with major depressive disorder are significan ...
Effects of Chronic Methylphenidate on Cocaine Self
Effects of Chronic Methylphenidate on Cocaine Self

... biting the leg and/or harness) as well as increased locomotion. In R-1429, treatment with 0.03 mg/kg per hour MPD produced an approximately 35% decrease in the number of injections earned after 1 week that was maintained at the end of the second week. When the MPD dose was increased to 0.056 mg/kg p ...
9th International Workshop on Clinical
9th International Workshop on Clinical

... Results/Conclusions: Moxifloxacin and rifapentine PK data were best fit using one-compartment models with absorption transit compartments. The final rifapentine model included a semi-mechanistic auto-induction model. On the other hand, moxifloxacin data did not support the inclusion of an enzyme tur ...
Medication Administration
Medication Administration

... • Lasix- check K+ levels • Administering electrolytes, know level before administration ...
Medication Administration
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... • Lasix- check K+ levels • Administering electrolytes, know level before administration ...
Drug abuse treatment as an HIV prevention strategy
Drug abuse treatment as an HIV prevention strategy

... that drug abuse treatment, especially MMT, is associated with decreased injection and sex-related HIV risk behaviors. The changes are most apparent in drug use, where 16 of the 17 studies examining drug use found that treatment was associated with less HIV risk (generally evidenced by less injection ...
New anti-tuberculosis drugs and regimens: 2015 update
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... In 2014, the World Health Organization (WHO) estimated 9 million new tuberculosis (TB) cases had occurred globally in 2013, 480 000 of them being affected by multidrug-resistant (MDR) Mycobacterium tuberculosis strains [1]. MDR-TB is defined as resistance in vitro to at least isoniazid and rifampici ...
Hepatitis C Treatment
Hepatitis C Treatment

... SIDE EFFECTS:Headache, fatigue, and influenza type symptoms, including myalgia, pyrexia, arthralgia, nausea, anorexia (and weight loss!) In addition, significant hematologic toxicity such as neutropenia and thrombocytopenia can occur. Eye issues can be a problem and it is suggested that a baseline O ...


... treatment A first requirement is a full and detailed clinical history (3,4). Some authors recommend complementary measures such as a complete blood test including red cell count, folic acid, ferritin and vitamin B12, with the purpose of discarding possible underlying systemic causes (vitamin deficie ...
Clinical Discussion of Special Populations - M
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... women by affecting gastric emptying (i.e., change drug transit time between non-pregnant women, throughout pregnancy, and at menopause). • Women tend to have a lower body weight, higher percentage body fat, and lower plasma volumes than men. Differences in body composition also influence the absorpt ...
Atomoxetine for ADHD in children and adolescents
Atomoxetine for ADHD in children and adolescents

... ADHD where available. Where patients are continuing treatment with atomoxetine beyond 1 year, re-evaluation of the need for therapy by a specialist in the treatment of ADHD is recommended. This document has been developed based on the best available knowledge at the time of publishing. Clinicians s ...
Sample Opioid Treatment Agreements
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... 12. The use of alcohol and opioid medications is contraindicated. 13. You agree and understand that your physician reserves the right to perform random or unannounced urine drug testing. If requested to provide a urine sample, you agree to cooperate. If you decide not to provide a urine sample, you ...
Beers Criteria Public Translation
Beers Criteria Public Translation

... have side effects when you take medications. Older people usually have more health problems and take more medications than younger people. Because of this, they are also more likely to experience dangerous drug-drug interactions. Every year, one in three adults 65 or older has one or more adverse (h ...
PCP & Ketamine
PCP & Ketamine

... Cerebral cortex and hippocampus contain many NMDA receptors Behavioral and subjective effects are thought to be mediated by NMDA receptor antagonism Dextromethorphan is common in OTC cough and cold medications and is another noncompetitive NMDA antagonist with abuse potential ...
учитесь читать аннотации к лекарственным препаратам
учитесь читать аннотации к лекарственным препаратам

... come from many different sources. Some drugs are obtained from parts of plants, such as the roots, leaves, and fruit. Examples of such drugs are digitalis (from the foxglove plant) and antibiotics such as penicillin and erythromycin (from lower plants called moulds). Drugs can also be obtained from ...
organisms was completely prevented and since it is an
organisms was completely prevented and since it is an

... patients themselves did not know that the series being controlled and were under the impression ...
AGS Beers Criteria Summary for Patients and Caregivers.
AGS Beers Criteria Summary for Patients and Caregivers.

... have side effects when you take medications. Older people usually have more health problems and take more medications than younger people. Because of this, they are also more likely to experience dangerous drug-drug interactions. Every year, one in three adults 65 or older has one or more adverse (h ...
168767_DrMaddin - Skin Therapy Letter
168767_DrMaddin - Skin Therapy Letter

... Jan D. Bos, University of Amsterdam, Amsterdam; Enno Christophers, Universitäts-Hautklinik, Kiel; Hugo Degreef, Catholic University, Leuven; Richard L. Dobson, Medical University of South Carolina, Charleston; Boni E. Elewski, Case Western Reserve University, Cleveland; Barbara A. Gilchrest, Boston ...
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Polysubstance dependence



A person with polysubstance dependence is psychologically addicted to being in an intoxicated state without a preference for one particular substance. Although any combination of three drugs can be used, studies have shown that alcohol is commonly used with another substance. This is supported by one study on polysubstance use that separated participants who used multiple substances into groups based on their preferred drug. The three substances were cocaine, alcohol, and heroin, which implies that those three are very popular. Other studies have found that opiates, cannabis, amphetamines, hallucinogens, inhalants and benzodiazepines are often used in combination as well. The results of a long-term or longitudinal study on substance use led the researchers to observe that excessively using or relying on one drug increased the probability of excessively using or relying on another drug.
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