Post-Exposure Prophylaxis after Non-Occupational and
... Ultimately, the decision to prescribe PEP needs to be made on a case-by-case basis, considering all the variables. These guidelines are not prescriptive, but put forward cases where PEP is recommended and the benefit of treatment is likely to exceed harm. Situations where there is greater uncertaint ...
... Ultimately, the decision to prescribe PEP needs to be made on a case-by-case basis, considering all the variables. These guidelines are not prescriptive, but put forward cases where PEP is recommended and the benefit of treatment is likely to exceed harm. Situations where there is greater uncertaint ...
Parenteral Route of medication
... injection is that as said before is easy accessible and patients are generally a lot more comfortable with exposing their arms as opposed to another body area. • Disadvantages to this site are the size of the muscle mass is small in relation to other IM injection sites. The deltoid intramuscular inj ...
... injection is that as said before is easy accessible and patients are generally a lot more comfortable with exposing their arms as opposed to another body area. • Disadvantages to this site are the size of the muscle mass is small in relation to other IM injection sites. The deltoid intramuscular inj ...
Guideline on Alcohol Dependence - EMA
... evidence that those milder forms of anxiety and depression often resolve with abstinence in patients with alcohol dependence. In order to address all these differences, several subtype classifications of alcohol-dependent patients were developed, but none of them is currently in widespread use or ge ...
... evidence that those milder forms of anxiety and depression often resolve with abstinence in patients with alcohol dependence. In order to address all these differences, several subtype classifications of alcohol-dependent patients were developed, but none of them is currently in widespread use or ge ...
Prolonged Circulation Time and Enhanced
... rate constants. The area under the concentration*time curve (AUC) was calculated from the sums of the ratios Al/kl and A2/k2. There were no significant differences between AUC values based on compartmental parameters and those based on the trapezoidal rule. In Doxil-injected patients, the AUC extrap ...
... rate constants. The area under the concentration*time curve (AUC) was calculated from the sums of the ratios Al/kl and A2/k2. There were no significant differences between AUC values based on compartmental parameters and those based on the trapezoidal rule. In Doxil-injected patients, the AUC extrap ...
(PSD) July 2015 PBAC Meeting
... Leuprorelin is currently listed on the PBS for the treatment of locally advanced (equivalent to stage C) or metastatic (equivalent to stage D) carcinoma of the prostate in two forms: a subcutaneous injection and an intramuscular injection. There are four strengths listed for the subcutaneous injecti ...
... Leuprorelin is currently listed on the PBS for the treatment of locally advanced (equivalent to stage C) or metastatic (equivalent to stage D) carcinoma of the prostate in two forms: a subcutaneous injection and an intramuscular injection. There are four strengths listed for the subcutaneous injecti ...
Breakdown of the Blood-Ocular Barrier as a Strategy for the
... can provide special properties to the drug molecule. Macugen®, a marketed treatment for neovascular age-related macular degeneration, is a nanoconjugate of an oligonucleotide (aptamer) with two polyethylene glycols (PEG) that prolongs the half-life of the drug in the vitreous humor [41]. Our laborat ...
... can provide special properties to the drug molecule. Macugen®, a marketed treatment for neovascular age-related macular degeneration, is a nanoconjugate of an oligonucleotide (aptamer) with two polyethylene glycols (PEG) that prolongs the half-life of the drug in the vitreous humor [41]. Our laborat ...
Antiretroviral Therapy for HIV Infection: When to Initiate - IAS-USA
... had CD4+ cell counts of 500/μL or higher. As shown in Figure 2, risk of death or severe HIV-related illness, the primary end point, was reduced with early antiretroviral therapy with or without isoniazid preventive treatment among those with CD4+ cell counts of 500/μL or higher. The benefits of immed ...
... had CD4+ cell counts of 500/μL or higher. As shown in Figure 2, risk of death or severe HIV-related illness, the primary end point, was reduced with early antiretroviral therapy with or without isoniazid preventive treatment among those with CD4+ cell counts of 500/μL or higher. The benefits of immed ...
P HO I HA
... IVAX label; after elimination of the supporting clinical data, a company may not suggest a dosing regimen that is unsupported by data in its label - inclusion of the downward titration statement would be misleading and result in the drug being data in misbranded ." Therefore, because teaching a dosa ...
... IVAX label; after elimination of the supporting clinical data, a company may not suggest a dosing regimen that is unsupported by data in its label - inclusion of the downward titration statement would be misleading and result in the drug being data in misbranded ." Therefore, because teaching a dosa ...
product monograph rescriptor
... controlled trials who received RESCRIPTOR 400 mg tid. Dose titration does not significantly reduce the incidence of rash. Skin rash is more common in patients with lower CD4 cell counts and typically occurs within 1 to 3 weeks of treatment. Severe and life threatening skin reactions have occurred on ...
... controlled trials who received RESCRIPTOR 400 mg tid. Dose titration does not significantly reduce the incidence of rash. Skin rash is more common in patients with lower CD4 cell counts and typically occurs within 1 to 3 weeks of treatment. Severe and life threatening skin reactions have occurred on ...
Promoting Antibiotic Discovery and Development
... infectious to chronic diseases is partly credited with raising average life expectancy by over 30 years. Much of this increase has been attributed to massive reductions in infectious disease mortality, which disproportionately impacts the young. These shifts have come to be known as an “epidemiologi ...
... infectious to chronic diseases is partly credited with raising average life expectancy by over 30 years. Much of this increase has been attributed to massive reductions in infectious disease mortality, which disproportionately impacts the young. These shifts have come to be known as an “epidemiologi ...
The Economic Cost of HIV/AIDS in Canada JoAnn Kingston-Riechers, PhD
... testing for HIV and received a positive result and has one or more of the clinical illnesses, or indicator diseases, that characterize AIDS (Canadian AIDS Society, Centre for Infectious Disease Prevention and Control, 2002). The majority of people begin to experience symptoms of an HIV infection wit ...
... testing for HIV and received a positive result and has one or more of the clinical illnesses, or indicator diseases, that characterize AIDS (Canadian AIDS Society, Centre for Infectious Disease Prevention and Control, 2002). The majority of people begin to experience symptoms of an HIV infection wit ...
Local adaptation versus standardization? - unu-merit
... to an infection with a resistant strain or due to poor treatment with inadequate drugs, insufficient drugs, selective, unstructured drug intake, poor drug quality or irregular drug supply (CTD 2007). In countries like India, with high numbers of TB patients, weak health systems and an unregulated p ...
... to an infection with a resistant strain or due to poor treatment with inadequate drugs, insufficient drugs, selective, unstructured drug intake, poor drug quality or irregular drug supply (CTD 2007). In countries like India, with high numbers of TB patients, weak health systems and an unregulated p ...
Rebecca Lawrence and Colin Baird
... On buprenorphine – 0 On gabapentin or pregabalin – 14 Use of NPS – 2 Problem alcohol use – 13 Cannabis use – 15 Benzodiazepines frequently used / prescribed ...
... On buprenorphine – 0 On gabapentin or pregabalin – 14 Use of NPS – 2 Problem alcohol use – 13 Cannabis use – 15 Benzodiazepines frequently used / prescribed ...
A Guideline for the Clinical Management of Opioid Use Disorder
... The BC Centre on Substance Use (BCCSU) is a new provincially networked resource with a mandate to develop, implement and evaluate evidence-based approaches to substance use and addiction. The BCCSU’s focus is on three strategic areas including research and evaluation, education and training, and cli ...
... The BC Centre on Substance Use (BCCSU) is a new provincially networked resource with a mandate to develop, implement and evaluate evidence-based approaches to substance use and addiction. The BCCSU’s focus is on three strategic areas including research and evaluation, education and training, and cli ...
Anticoagulant Presentation
... • Aspirin: Primary prevention of MI in high risk persons Secondary prevention of MI,TIA & stroke • Clopidogrel: for persons who can’t take aspirin • Aspirin+clopidogrel: Acute coronary syndromes ...
... • Aspirin: Primary prevention of MI in high risk persons Secondary prevention of MI,TIA & stroke • Clopidogrel: for persons who can’t take aspirin • Aspirin+clopidogrel: Acute coronary syndromes ...
Clinical Drug Testing in Primary Care Manual
... This Technical Assistance Publication (TAP), Clinical Drug Testing in Primary Care, is for clinical practitioners— physicians, nurse practitioners, and physician assistants— health centers. The publication provides information that practitioners need when deciding whether to introduce drug testing i ...
... This Technical Assistance Publication (TAP), Clinical Drug Testing in Primary Care, is for clinical practitioners— physicians, nurse practitioners, and physician assistants— health centers. The publication provides information that practitioners need when deciding whether to introduce drug testing i ...
AMA 115 PowerPoint
... • The immune system is a group of cells and organs that protect your body by fighting disease. The human immune system usually finds and kills viruses fairly quickly. • So if the body's immune system attacks and kills viruses, what's the problem? • Different viruses attack different parts of the bod ...
... • The immune system is a group of cells and organs that protect your body by fighting disease. The human immune system usually finds and kills viruses fairly quickly. • So if the body's immune system attacks and kills viruses, what's the problem? • Different viruses attack different parts of the bod ...
Internet Pharmacies: Global threat requires a global approach to
... comparison of products. This is especially relevant to consumers who live in sparsely populated areas where there are no pharmaceutical services, and disabled people who have difficulty in travelling to a Pharmacy11, among others; • Increased consumer information and information exchange. Through on ...
... comparison of products. This is especially relevant to consumers who live in sparsely populated areas where there are no pharmaceutical services, and disabled people who have difficulty in travelling to a Pharmacy11, among others; • Increased consumer information and information exchange. Through on ...
This PDF is a selec on from a published volume... Bureau of Economic Research
... countries, requiring that new compounds meet standards of safety, efficacy, and manufacturing quality as a condition of market access. The main initial focus of regulation since the 1930s was safety, and this has reemerged recently as a critical issue. Since the 1960s most countries also require preap ...
... countries, requiring that new compounds meet standards of safety, efficacy, and manufacturing quality as a condition of market access. The main initial focus of regulation since the 1930s was safety, and this has reemerged recently as a critical issue. Since the 1960s most countries also require preap ...
U N I V E R S I T Y ... F Y 1 5 U T I L... 7 / 1 / 2 0 1 4 ... L
... Professional – Primary Care or Specialist Care Physician services Average Contract Size – The average number of dependents (Spouse and Children) for each enrolled employee ...
... Professional – Primary Care or Specialist Care Physician services Average Contract Size – The average number of dependents (Spouse and Children) for each enrolled employee ...
6: Endocrine system - Gateshead Health NHS Foundation Trust
... Liraglutide may be an option in those experiencing excessive side-effects with exenatide. It is administered once a day independent of food intake, which may suit those with irregular working patterns. ...
... Liraglutide may be an option in those experiencing excessive side-effects with exenatide. It is administered once a day independent of food intake, which may suit those with irregular working patterns. ...
Sample chapter - Pharmaceutical Press
... purpose and some have some biological activity. The reason we discuss in this textbook adverse events which may follow from administration of medicines is that some of the problems that arise are the result of excipients interacting physically or chemically with drugs or with themselves, or creating ...
... purpose and some have some biological activity. The reason we discuss in this textbook adverse events which may follow from administration of medicines is that some of the problems that arise are the result of excipients interacting physically or chemically with drugs or with themselves, or creating ...
Powerpoint - Sexual Assault Forensic Examiner Technical Assistance
... • The initial protocol model used was from the British Columbia guidelines, until new guidelines were adopted by the Centers for Disease Control in 2004. www.safeta.org ...
... • The initial protocol model used was from the British Columbia guidelines, until new guidelines were adopted by the Centers for Disease Control in 2004. www.safeta.org ...
Harm reduction
Harm reduction (or harm minimization) is a range of public health policies designed to reduce the harmful consequences associated with various human behaviors, both legal and illegal. Harm reduction policies are used to manage behaviors such as recreational drug use and sexual activity in numerous settings that range from services through to geographical regions. Critics of harm reduction typically believe that tolerating risky or illegal behaviour sends a message to the community that such behaviours are acceptable and that some of the actions proposed by proponents of harm reduction do not reduce harm over the long term.Needle-exchange programmes reduce the likelihood of users of heroin and other drugs sharing the syringes and using them more than once. Syringe-sharing can lead to infections such as HIV or hepatitis C can spread from user to users through the reuse of syringes contaminated with infected blood. Needle and syringe programme (NSP) and Opioid Substitution Therapy (OST) outlets in some settings offer basic primary health care. Safe injection site are legally sanctioned, medically supervised facilities designed to address public nuisance associated with drug use and provide a hygienic and stress-free environment for drug consumers. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, and access to medical staff.Opioid replacement therapy (ORT), or opioid substitution therapy (OST), is the medical procedure of replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. Another approach is Heroin assisted treatment, in which medical prescriptions for pharmaceutical heroin (diacetylmorphine) are provided to heroin-dependent people. Toronto's Seaton House became the first homeless shelter in Canada to operate a ""wet shelter"" on a ""managed alcohol"" principle in which clients are served a glass of wine once an hour unless staff determine that they are too inebriated to continue. Previously, homeless alcoholics opted to stay on the streets often seeking alcohol from unsafe sources such as mouthwash, rubbing alcohol or industrial products which, in turn, resulted in frequent use of emergency medical facilities.A high amount of media coverage exists informing users of the dangers of driving drunk. Most alcohol users are now aware of these dangers and safe ride techniques like 'designated drivers' and free taxicab programmes are reducing the number of drunk-driving accidents. Many schools now provide safer sex education to teen and pre-teen students, who may engage in sexual activity. Since some adolescents are going to have sex, a harm-reductionist approach supports a sexual education which emphasizes the use of protective devices like condoms and dental dams to protect against unwanted pregnancy and the transmission of STIs. Since 1999 some countries have legalized prostitution, such as Germany (2002) and New Zealand (2003).Many street-level harm-reduction strategies have succeeded in reducing HIV transmission in injecting drug users and sex-workers. HIV education, HIV testing, condom use, and safer-sex negotiation greatly decreases the risk to the disease.