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Heterogeneity of Concentrated Prescribing Behavior
Heterogeneity of Concentrated Prescribing Behavior

... pharmaceutical treatments are available. Suppose that, given the clinical evidence, patient response to a given treatment is idiosyncratic and unpredictable in terms of both efficacy and side effects. What treatment algorithms might the physician employ to learn about the efficacy and tolerability o ...
Hepatitis C among drug users in Europe: epidemiology, treatment
Hepatitis C among drug users in Europe: epidemiology, treatment

... antibody prevalence range anywhere between 15 % and 84 %. Moreover, there is still significant ongoing transmission of this disease, with new injectors often becoming infected relatively rapidly. This means that HCV prevention remains one of the major challenges for Europe’s public health response t ...
ANTI-FUNGAL ACTIVITY OF MICROEMULSION BASED FLUCONAZOLE GEL FOR
ANTI-FUNGAL ACTIVITY OF MICROEMULSION BASED FLUCONAZOLE GEL FOR

... barrier to the topical penetration of actives [18]. Thus, treatment of nail disorders, such as fungal infections, remains a challenge because of the difficulty encountered in achieving therapeutic concentrations of drugs at the site of infection, which is often under the nail [19]. Investigation of ...
SC13-16.03. F155. Powerpoint Training Revision
SC13-16.03. F155. Powerpoint Training Revision

... “Experimental research” refers to the development, testing and use of a clinical treatment, such as an investigational drug or therapy that has not yet been approved by the FDA or medical community as effective and conforming to accepted medical practice. “Health care decision-making” refers to cons ...
Guidelines on Container Closure Systems Version 1.3
Guidelines on Container Closure Systems Version 1.3

... veterinary drugs and biological products, and safety of cosmetics, through administration of a national regulatory system which is consistent with international best practice. Through our mission, we also provide accurate and scientific-based information to the public and healthcare ...
Chronic Viral Hepatitis in the Pediatric Population
Chronic Viral Hepatitis in the Pediatric Population

... Subjects who resolved an infection from a single contaminated source had strong HCV-specific T-cell immunity 18 years later Takaki 2000 Nature Med ...
Principles of Addictions and the Law: Applications in Forensic
Principles of Addictions and the Law: Applications in Forensic

... and the law. On the one hand, addiction is considered a disabling illness. As early as 1925 the United States Supreme Court stated that addicts “are diseased and proper subjects for … treatment.” On the other hand, addiction is considered willful misconduct. Although court decisions, the Rehabilitat ...
Drug delivery for skin - Abdel Hamid Derm Atlas
Drug delivery for skin - Abdel Hamid Derm Atlas

... exostosis, myalgia & arthralgia. Transiently liver function tests & serum lipids are also seen. A potential psychiatric side effects of systemic retinoids are controversial & care should be taken when prescribing for patients with a history of depression or suicidal ideation. @ Early users of retino ...
Clinical Practice Guidelines on Dyslipidaemia
Clinical Practice Guidelines on Dyslipidaemia

... measurement of carotid intima-medial thickness (IMT) by ultrasound (more than 75 percentile for age and sex) measurement of coronary calcium score by electron beam computed tomography (EBCT) – In accordance with recent reports there is insufficient evidence to recommend EBCT for indiscriminate scree ...
The Corrosive Effects of Alcohol and Drug Misuse on
The Corrosive Effects of Alcohol and Drug Misuse on

... lost by the 552 individuals who died prematurely in New Hampshire in 2012 as a result of alcohol and drugs. These additional mortality costs are not included in the $1.84 billion total cost to New Hampshire. By far the greatest cost of substance misuse in New Hampshire is in the form of lost product ...
NEWSLETTER - Anesthesia Patient Safety Foundation
NEWSLETTER - Anesthesia Patient Safety Foundation

... the activities of the foundation during the past calendar year. As in my previous annual reports, I believe it is important to recognize that APSF, as an advocacy group, does not write standards. Recommendations developed and promulgated by APSF are intended to assist professionals who are responsib ...
DUinventory_October2..
DUinventory_October2..

... Figure 1. PubMed results for “hospital drug utilisation” AND “calcium channel blockers ......... 79 Figure 2. PubMed results for “hospital drug utilisation” AND “antiepileptics” ........................ 80 Figure 3. PubMed results for “hospital drug utilisation” AND “antidepressants” ............... ...
Giving injections
Giving injections

... Briskly insert the needle through the skin and into the vein. A flash of blood will be seen in the tubing when the tlp of the needle enters the vein. Carefully advance the needIe an additional 3 to 5 mm into the vein. Attach a 5 mL syringe to the extension tubing and aspirate blood. Remove the toumi ...
Zambia Consolidated Guidelines for Treatment and Prevention of
Zambia Consolidated Guidelines for Treatment and Prevention of

... Zambia has had an effective treatment and prevention HIV/AIDS response for over a decade now. During this time systems have been strengthened and access to care has been provided to many Zambians. The HIV epidemic is a significant challenge to many communities but strategies have been devised and im ...
American Thoracic Society
American Thoracic Society

... recommendation applies to both HIV-infected and uninfected persons. However, in the presence of HIV infection it is critically important to assess the clinical and bacteriologic response. If there is evidence of a slow or suboptimal response, therapy should be prolonged as judged on a case by case b ...
Independent review of the circumstances surrounding four serious
Independent review of the circumstances surrounding four serious

... The vast majority of medications administered intravenously to patients by healthcare professionals worldwide are done safely. Regrettably inadvertent drug errors do occur to adults and children on occasions due to human fallibility and systems failure.1,2,3,4,5 The NPSA have reported that between J ...
Anticonvulsants
Anticonvulsants

... Adverse Effects  Gingival Enlargement • This occurs in 50% of all chronic users. • It can appear in as little as a few weeks after beginning therapy or after several years of therapy. • Its cause is unknown. • The better the oral hygiene, the less likely it will occur or the less severe the lesions ...
June 2014 - University Health Services
June 2014 - University Health Services

... adherence, and routine viral load testing for all clients on ART. This guideline has been developed for all health workers in a health care setup including; medical specialists, medical of icers, clinical of icers, nurses, pharmacists, pharmaceutical technologists, nutrition ...
The Impact of Abbreviations on Patient Safety
The Impact of Abbreviations on Patient Safety

... writing of orders, which often include abbreviations. With prevent an error. Pharmacy and nursing are often charged the increased adoption of information technology, the use with contacting the prescriber when abbreviations conof abbreviations in drug data libraries and computer-entry found orders. ...
Local Coverage Determination for Urine Drug Testing (L36037)
Local Coverage Determination for Urine Drug Testing (L36037)

... An IA involves an antibody that reacts best with the stimulating drug, and reacts to a lesser extent (crossreactive) or not at all with other drugs in the drug class. While presumptive tests vary in their ability to detect illicit drugs such as tetrahydrocannabinol (THC), cocaine, 3,4-methylenediox ...
The challenge of new psychoactive substances
The challenge of new psychoactive substances

... It constitutes the first step in providing consolidated up to-date analysis, based primarily on the information shared by Member States and the International Collaborative Exercise network of drug analysis laboratories. It is hoped that the information on new psychoactive substances presented in thi ...
Priority communicable diseases
Priority communicable diseases

... Although none of the antiviral drugs have been shown to prevent avian influenza, studies conducted through the WHO Global Influenza Surveillance Network have shown that the antiviral drug oseltamivir may be the most useful for treatment. However, it is expensive and currently in great demand. In add ...
Position of the American Dietetic Association: Nutrition Intervention
Position of the American Dietetic Association: Nutrition Intervention

... white women. Latinos had three times the prevalence rate of whites. The most affected minority groups were usually diagnosed at a later stage of HIV infection, when related or concurrent diseases were present. Delayed care may be more common in these groups due to lack of economic, insurance, and ot ...
Overdose Prevention and Take-Home Naloxone
Overdose Prevention and Take-Home Naloxone

... Prevention (CDC), overdose rates have increased roughly five-fold since 1990. The CDC attributes the rise in drug overdose deaths to a higher use of prescription painkillers and increasing numbers of overdoses from cocaine and prescription sedatives. In 2008, the most recent year for which data is a ...
Opioid Antagonists in Pain Management
Opioid Antagonists in Pain Management

... their uses described in this report are off-label. Further investigations to assess the safety and efficacy of these applications would be appropriate. ...
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Harm reduction



Harm reduction (or harm minimization) is a range of public health policies designed to reduce the harmful consequences associated with various human behaviors, both legal and illegal. Harm reduction policies are used to manage behaviors such as recreational drug use and sexual activity in numerous settings that range from services through to geographical regions. Critics of harm reduction typically believe that tolerating risky or illegal behaviour sends a message to the community that such behaviours are acceptable and that some of the actions proposed by proponents of harm reduction do not reduce harm over the long term.Needle-exchange programmes reduce the likelihood of users of heroin and other drugs sharing the syringes and using them more than once. Syringe-sharing can lead to infections such as HIV or hepatitis C can spread from user to users through the reuse of syringes contaminated with infected blood. Needle and syringe programme (NSP) and Opioid Substitution Therapy (OST) outlets in some settings offer basic primary health care. Safe injection site are legally sanctioned, medically supervised facilities designed to address public nuisance associated with drug use and provide a hygienic and stress-free environment for drug consumers. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, and access to medical staff.Opioid replacement therapy (ORT), or opioid substitution therapy (OST), is the medical procedure of replacing an illegal opioid, such as heroin, with a longer acting but less euphoric opioid; methadone or buprenorphine are typically used and the drug is taken under medical supervision. Another approach is Heroin assisted treatment, in which medical prescriptions for pharmaceutical heroin (diacetylmorphine) are provided to heroin-dependent people. Toronto's Seaton House became the first homeless shelter in Canada to operate a ""wet shelter"" on a ""managed alcohol"" principle in which clients are served a glass of wine once an hour unless staff determine that they are too inebriated to continue. Previously, homeless alcoholics opted to stay on the streets often seeking alcohol from unsafe sources such as mouthwash, rubbing alcohol or industrial products which, in turn, resulted in frequent use of emergency medical facilities.A high amount of media coverage exists informing users of the dangers of driving drunk. Most alcohol users are now aware of these dangers and safe ride techniques like 'designated drivers' and free taxicab programmes are reducing the number of drunk-driving accidents. Many schools now provide safer sex education to teen and pre-teen students, who may engage in sexual activity. Since some adolescents are going to have sex, a harm-reductionist approach supports a sexual education which emphasizes the use of protective devices like condoms and dental dams to protect against unwanted pregnancy and the transmission of STIs. Since 1999 some countries have legalized prostitution, such as Germany (2002) and New Zealand (2003).Many street-level harm-reduction strategies have succeeded in reducing HIV transmission in injecting drug users and sex-workers. HIV education, HIV testing, condom use, and safer-sex negotiation greatly decreases the risk to the disease.
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