Topologically Non-linked Circular Duplex DNA
... These authors believe that circular DNA is not, in general, topologically helical, but rather has a structure not unlike those proposed by Rodley et al. (1976) and Sasisekharan et al. (1978), in which the two individual single-stranded circular half-chromosomes twist about each other alternately to ...
... These authors believe that circular DNA is not, in general, topologically helical, but rather has a structure not unlike those proposed by Rodley et al. (1976) and Sasisekharan et al. (1978), in which the two individual single-stranded circular half-chromosomes twist about each other alternately to ...
Mutation Screening of the EXT Genes in Patients with Hereditary
... acids from the carboxyl terminus of the EXT1 protein. Because the conserved carboxy-terminal region of the EXT1 protein contains a putatively catalytic domain for the synthesis of heparan sulfate (McCormick et al., 2000), the truncated EXT1 protein is probably inactive or degraded rapidly, resulting ...
... acids from the carboxyl terminus of the EXT1 protein. Because the conserved carboxy-terminal region of the EXT1 protein contains a putatively catalytic domain for the synthesis of heparan sulfate (McCormick et al., 2000), the truncated EXT1 protein is probably inactive or degraded rapidly, resulting ...
New DNA test for craniomandibular osteopathy (CMO) in three
... known by several synonyms, such as ‘mandibular periostitis’, ‘Westie jaw’, ‘Scottie jaw’ and ‘lion’s jaw’. The CMO disease was first recognized in England more than 50 years ago and since that time CMO is suspected to be inherited as monogenic trait. The disease predominates in Cairn terriers, Scott ...
... known by several synonyms, such as ‘mandibular periostitis’, ‘Westie jaw’, ‘Scottie jaw’ and ‘lion’s jaw’. The CMO disease was first recognized in England more than 50 years ago and since that time CMO is suspected to be inherited as monogenic trait. The disease predominates in Cairn terriers, Scott ...
Cot-1 banding of human chromosomes using fluorescence
... (Fig. IA). There is high contrast between positive and negative bands. This Cot-1 banding image was recorded in a computer, and then Q-banding was performed on the same spread by conventional method (Fig. 1B). Then, these two fluorescent images of Cot-1 banding and Q-banding were computer-graphicall ...
... (Fig. IA). There is high contrast between positive and negative bands. This Cot-1 banding image was recorded in a computer, and then Q-banding was performed on the same spread by conventional method (Fig. 1B). Then, these two fluorescent images of Cot-1 banding and Q-banding were computer-graphicall ...
Polycomb Group silencers collaborate with Notch pathway to cause
... semi-lethal in trans-heterozygosity with the two deficiencies of the 47A11-B1 region. The surviving adults were either fertile or sterile and grandchildless (DFM and MD, unpublished results). Eight of these were identified as psq mutations by their failure to complement mutant psq alleles from other ...
... semi-lethal in trans-heterozygosity with the two deficiencies of the 47A11-B1 region. The surviving adults were either fertile or sterile and grandchildless (DFM and MD, unpublished results). Eight of these were identified as psq mutations by their failure to complement mutant psq alleles from other ...
Crystal structure of the nucleosome core particle at 2.8 Å
... turns of DNA double helix, which arcs around them along their long axes to generate a 140° bend. The histonefold motif is related to its counterpart in a pair by pseudo-twofold symmetry, with the symmetry axis passing between the two long, 8-turn α2 helices at their crossover. Their antiparallel arr ...
... turns of DNA double helix, which arcs around them along their long axes to generate a 140° bend. The histonefold motif is related to its counterpart in a pair by pseudo-twofold symmetry, with the symmetry axis passing between the two long, 8-turn α2 helices at their crossover. Their antiparallel arr ...
Medullary thyroid cancer
... that are not listed include 532, 534, 635, 636, 638, 639, 778, and 852. ...
... that are not listed include 532, 534, 635, 636, 638, 639, 778, and 852. ...
The Close Relationship Between the A and B Genomes in Avena L
... group tetraploids, and a second set of chromosomes with distinct structure. This second set was composed of two pairs of medium chromosomes (similar to the ones present in the As genome), four pairs of submedian chromosomes (two of which were similar to As genome chromosomes and two pairs which were ...
... group tetraploids, and a second set of chromosomes with distinct structure. This second set was composed of two pairs of medium chromosomes (similar to the ones present in the As genome), four pairs of submedian chromosomes (two of which were similar to As genome chromosomes and two pairs which were ...
p53 powerpoint
... associated with human cancers (bcl= b cell lymphoma resulting from a translocation event) ...
... associated with human cancers (bcl= b cell lymphoma resulting from a translocation event) ...
The Cutting Edge of Lung Cancer Research
... Cell regulation pathways disrupted in lung cancer cells may have mutations in several different components if the pathway. Mutations in dominant and recessive oncogene products disrupt several cell regulation pathways and mutations often occur in different components of the same pathway. Pathways wh ...
... Cell regulation pathways disrupted in lung cancer cells may have mutations in several different components if the pathway. Mutations in dominant and recessive oncogene products disrupt several cell regulation pathways and mutations often occur in different components of the same pathway. Pathways wh ...
Uracil in DNA – occurrence, consequences and repair
... studies on possible B-cell abnormalities particularly relevant in an Ung-deficient mouse model. Such abnormalities would probably occur late in life since Ung-deficient mice do not show obvious signs of phenotypic changes in the first 12 months (Nilsen et al., 2000). Studies on the possible occurren ...
... studies on possible B-cell abnormalities particularly relevant in an Ung-deficient mouse model. Such abnormalities would probably occur late in life since Ung-deficient mice do not show obvious signs of phenotypic changes in the first 12 months (Nilsen et al., 2000). Studies on the possible occurren ...
Meiosis
... – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated chromosomes – At anaphase I, it is homologous chromosomes, instead of sister chromatids, that separate ...
... – At the metaphase plate, there are paired homologous chromosomes (tetrads), instead of individual replicated chromosomes – At anaphase I, it is homologous chromosomes, instead of sister chromatids, that separate ...
Microsynth GmbH
... Figure 5-1: Sequence electropherogram depicting peaks within noisy background "Noisy" sequences are easily recognizable by the multiple peaks and a large number of "N"s (if your sequencing preferences are set to “N for unclear bases”). An "N" can indicate the actual presence of two nucleotides in th ...
... Figure 5-1: Sequence electropherogram depicting peaks within noisy background "Noisy" sequences are easily recognizable by the multiple peaks and a large number of "N"s (if your sequencing preferences are set to “N for unclear bases”). An "N" can indicate the actual presence of two nucleotides in th ...
1. Introduction
... in the phenomenon of cell division (mitosis). During the first decade of the twentieth century, the Mendel’s laws of heredity in which each individual present two “factors” (identical or not) for each trait, with one “factor” coming from each parent, was rediscovered. In 1902, Walter Sutton (1902) n ...
... in the phenomenon of cell division (mitosis). During the first decade of the twentieth century, the Mendel’s laws of heredity in which each individual present two “factors” (identical or not) for each trait, with one “factor” coming from each parent, was rediscovered. In 1902, Walter Sutton (1902) n ...
Trouble Shooting Guide
... Figure 5-1: Sequence electropherogram depicting peaks within noisy background "Noisy" sequences are easily recognizable by the multiple peaks and a large number of "N"s (if your sequencing preferences are set to “N for unclear bases”). An "N" can indicate the actual presence of two nucleotides in th ...
... Figure 5-1: Sequence electropherogram depicting peaks within noisy background "Noisy" sequences are easily recognizable by the multiple peaks and a large number of "N"s (if your sequencing preferences are set to “N for unclear bases”). An "N" can indicate the actual presence of two nucleotides in th ...
Full Text - Molecular Biology and Evolution
... jointly beneficial effect, 4 of the 5 mutations reduced resistance in some combinations. Additionally, from this resistance data one can calculate the likelihood of evolution following a particular mutational trajectory—an ordering of the 5 mutations—from the initial TEM-1 allele to the high-resista ...
... jointly beneficial effect, 4 of the 5 mutations reduced resistance in some combinations. Additionally, from this resistance data one can calculate the likelihood of evolution following a particular mutational trajectory—an ordering of the 5 mutations—from the initial TEM-1 allele to the high-resista ...
horiuchi - Genetics
... F-phoA+phoB (LEPI ) . However, these data indicate that there is no complementation between the phoB and phoRc mutations f o r AP synthesis. In order to ensure that HL13 contains FJphoB and that a valid complementation test was performed, other possible genotypes have been excluded. HL13 can transfe ...
... F-phoA+phoB (LEPI ) . However, these data indicate that there is no complementation between the phoB and phoRc mutations f o r AP synthesis. In order to ensure that HL13 contains FJphoB and that a valid complementation test was performed, other possible genotypes have been excluded. HL13 can transfe ...
Chapter 11 – Patterns of Chromosomal Inheritance
... A segment of a chromosome is turned around 180 degrees (backward). This type of mutation will become more evident when we look at how a gene will encode a protein Translocation Movement of a chromosome segment from one chromosome to another nonhomologous chromosome Deletion The loss of a segment of ...
... A segment of a chromosome is turned around 180 degrees (backward). This type of mutation will become more evident when we look at how a gene will encode a protein Translocation Movement of a chromosome segment from one chromosome to another nonhomologous chromosome Deletion The loss of a segment of ...
notes
... deleterious mutations. For example, in Sweden, about 4% of offspring born to unrelated parents have some form of disease or physical or mental defect, whereas among first-cousin marriages the proportion is 16%. A crude estimate of the number of loci leading to such defects suggests that every indivi ...
... deleterious mutations. For example, in Sweden, about 4% of offspring born to unrelated parents have some form of disease or physical or mental defect, whereas among first-cousin marriages the proportion is 16%. A crude estimate of the number of loci leading to such defects suggests that every indivi ...
LAB 1: Scientific Method/Tools of Scientific Inquiry
... one of four possible nitrogenous bases (“bases” for short) on the other. The phosphate group is acidic and thus negatively charged. This is why DNA has a net negative charge. Because all nucleotides in DNA contain deoxyribose they are called deoxyribonucleotides, though for simplicity we will just c ...
... one of four possible nitrogenous bases (“bases” for short) on the other. The phosphate group is acidic and thus negatively charged. This is why DNA has a net negative charge. Because all nucleotides in DNA contain deoxyribose they are called deoxyribonucleotides, though for simplicity we will just c ...
Sex Linked Inheritance, Chromosome Mapping
... Euploidy is lethal in most animal species, but often tolerated in plants, where it has played a role in speciation and diversification. Monoploidy and polyploidy can result when either round of meiotic division lacks cytokinesis, or when meiotic nondisjunction occurs for all chromosomes. Punjab EDU ...
... Euploidy is lethal in most animal species, but often tolerated in plants, where it has played a role in speciation and diversification. Monoploidy and polyploidy can result when either round of meiotic division lacks cytokinesis, or when meiotic nondisjunction occurs for all chromosomes. Punjab EDU ...
NIOSH 2013 Pesticide Handler Personal Protective Technology Stakeholders Meeting
... High terbufos exposure ...
... High terbufos exposure ...
Mutagen
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens. Not all mutations are caused by mutagens: so-called ""spontaneous mutations"" occur due to spontaneous hydrolysis, errors in DNA replication, repair and recombination.