Document
... your knowledge of biology. When a culture of cells is exposed to gamma rays, chromosome damage results. This damage is very evident when the cells are stained and observed with a compound light microscope. The chromosome damage is primarily in the form of breaks and gaps, which are commonly referred ...
... your knowledge of biology. When a culture of cells is exposed to gamma rays, chromosome damage results. This damage is very evident when the cells are stained and observed with a compound light microscope. The chromosome damage is primarily in the form of breaks and gaps, which are commonly referred ...
SPA1: A New Genetic Locus Involved in Phytochrome A
... and Deng, 1996). Several types of screens for mutants have been used. One approach focused on isolating mutants that are constitutively photomorphogenic, namely, constitutively photomorphogenic (cop), deetiolated (det), and fusca (fus). cop, det, and fus dark-grown seedlings exhibit a light-grown mo ...
... and Deng, 1996). Several types of screens for mutants have been used. One approach focused on isolating mutants that are constitutively photomorphogenic, namely, constitutively photomorphogenic (cop), deetiolated (det), and fusca (fus). cop, det, and fus dark-grown seedlings exhibit a light-grown mo ...
![arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007](http://s1.studyres.com/store/data/014946021_1-c477dba1add7a260e278ca181f537c79-300x300.png)
arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007
... There are other important properties that will help us understand the experiments and theoretical proposals below. For instance, a polynucleotide has a global orientation, with one end a 5′ and the other end a 3′ , as described in Fig. 3. We will see in Sec. IV that this is important for the structu ...
... There are other important properties that will help us understand the experiments and theoretical proposals below. For instance, a polynucleotide has a global orientation, with one end a 5′ and the other end a 3′ , as described in Fig. 3. We will see in Sec. IV that this is important for the structu ...
Warren, ST and Ashley, CT: Triplet repeat expansion mutations: The example of fragile X syndrome. Annual Review of Neuroscience 18:77-99 (1995).
... localized this instability to a single 1.0-kb Pst I fragment, pfxa2, that was sequenced and found to contain an unusual CGG trinucleotide repeat of 43 copies. By using the polymerase chain reaction (PCR) and primers flanking the repeat, Kremer et al (1991a) mapped the region of instability in pfxa2 ...
... localized this instability to a single 1.0-kb Pst I fragment, pfxa2, that was sequenced and found to contain an unusual CGG trinucleotide repeat of 43 copies. By using the polymerase chain reaction (PCR) and primers flanking the repeat, Kremer et al (1991a) mapped the region of instability in pfxa2 ...
Calculating the Number of Genes
... • Chromosome mutations are variations from the wild-type condition in... – chromosome number, – chromosome structure, ...
... • Chromosome mutations are variations from the wild-type condition in... – chromosome number, – chromosome structure, ...
Genetics of Hemophilia
... Chromosomes consist of long strings of genes. A gene is the basic unit of inheritance. It codes for the sequence of amino acids in a protein. Humans have more than 25,000 genes. Each gene influences some aspect of body structure or function. Sometimes, as in hemophilia A or B, a single gene governs ...
... Chromosomes consist of long strings of genes. A gene is the basic unit of inheritance. It codes for the sequence of amino acids in a protein. Humans have more than 25,000 genes. Each gene influences some aspect of body structure or function. Sometimes, as in hemophilia A or B, a single gene governs ...
p53 in Hematologic Malignancies
... represent about 10% of the total p53 alterations. False-positives also can occur. For example, in one series of lymphomas, we found 50% of tumors with immunohistochemically detectable p53, but no mutations were detected in the p53 gene.7' This finding could be explained in part because we did not an ...
... represent about 10% of the total p53 alterations. False-positives also can occur. For example, in one series of lymphomas, we found 50% of tumors with immunohistochemically detectable p53, but no mutations were detected in the p53 gene.7' This finding could be explained in part because we did not an ...
Inhibition of RNA Synthesis by Anthracycline Analogs
... appear to be, at least in part, due to their ability to interact with DNA. ...
... appear to be, at least in part, due to their ability to interact with DNA. ...
TP53 mutations occur in 15.7% of ALL and are associated with MYC
... The most frequently mutated gene in cancer is TP53, which is well characterized in other hematological malignancies, including acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL). However, the frequency and prognostic impact of TP53 mutations has only rarely been studied in ALL thus ...
... The most frequently mutated gene in cancer is TP53, which is well characterized in other hematological malignancies, including acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL). However, the frequency and prognostic impact of TP53 mutations has only rarely been studied in ALL thus ...
Isolation, Characterization and Complementation
... reduction, there is considerable confusion about the identity of structural and regulatory genes involved in the process, In previous reports from this laboratory we have described nirA mutants (also called-fnr and nirR mutants: Cole & Ward, 1973; Lambden & Guest, 1976; Chippaux et al., 1978) which ...
... reduction, there is considerable confusion about the identity of structural and regulatory genes involved in the process, In previous reports from this laboratory we have described nirA mutants (also called-fnr and nirR mutants: Cole & Ward, 1973; Lambden & Guest, 1976; Chippaux et al., 1978) which ...
Human mitochondrial transfer RNAs: Role of pathogenic
... Most of the observed mtDNA changes represent neutral polymorphisms and have been used to track human migrations.70 The large prevalence of variations in tRNA genes calls for the elucidation of their pathogenicity. In addition, clinical misattribution of pathogenicity is an important issue due to the ...
... Most of the observed mtDNA changes represent neutral polymorphisms and have been used to track human migrations.70 The large prevalence of variations in tRNA genes calls for the elucidation of their pathogenicity. In addition, clinical misattribution of pathogenicity is an important issue due to the ...
The Deletion Stocks of Common Wheat
... segment from A. spettoldes Tausch (2n = 2x = 14, SS). We identified 436 deletions by C-banding. The deletion chromosomes were transmitted stably to the offspring. We selected deletion homozygotes in the progeny of the deletion heterozygotes and established homozygous lines for about 80% of the delet ...
... segment from A. spettoldes Tausch (2n = 2x = 14, SS). We identified 436 deletions by C-banding. The deletion chromosomes were transmitted stably to the offspring. We selected deletion homozygotes in the progeny of the deletion heterozygotes and established homozygous lines for about 80% of the delet ...
Could distal MSH2 upstream deletions cause HNPCC?
... The primer set for MSH2P4 is 10 kb upstream of MSH2 ...
... The primer set for MSH2P4 is 10 kb upstream of MSH2 ...
Xq28 duplications
... genes which may be thought of as individual instruction booklets (or recipes) that contain all the genetic information that tells the body how to develop, grow and function. Chromosomes (and hence genes) usually come in pairs with one member of each chromosome pair being inherited from each parent. ...
... genes which may be thought of as individual instruction booklets (or recipes) that contain all the genetic information that tells the body how to develop, grow and function. Chromosomes (and hence genes) usually come in pairs with one member of each chromosome pair being inherited from each parent. ...
Distribution and Concordance of N-Acetyltransferase Genotype and
... NAT2.4 Polymorphisms of NAT2 are known to result in variation of acetylation activity and have been associated with the incidence of several diseases (5). Generally, single-nt substitutions in NAT2 result in low activity, decreased expression, and enzyme instability (23). A slow acetylator phenotype ...
... NAT2.4 Polymorphisms of NAT2 are known to result in variation of acetylation activity and have been associated with the incidence of several diseases (5). Generally, single-nt substitutions in NAT2 result in low activity, decreased expression, and enzyme instability (23). A slow acetylator phenotype ...
2004-009_-Draft-Anne..
... an additional test based on a different biological principle should be used for detection. In all tests, positive and negative controls must be included. The use of products of commercial brands in this diagnostic protocol implies no approval of them to the exclusion of others that may also be suita ...
... an additional test based on a different biological principle should be used for detection. In all tests, positive and negative controls must be included. The use of products of commercial brands in this diagnostic protocol implies no approval of them to the exclusion of others that may also be suita ...
Drysdale_pheno_CSH
... some nebenkern are associated with two centrioles instead of one as in wild-type. Prometaphase I, Ontology Meeting metaphase I and Phenotype ...
... some nebenkern are associated with two centrioles instead of one as in wild-type. Prometaphase I, Ontology Meeting metaphase I and Phenotype ...
22q12 and 22q13 duplications
... babies described as ‘failure to thrive’. This term is used to describe a baby who has poor weight gain and physical growth failure over a period of time. The hypotonia that is common in babies with a 22q12/13 duplication can lead to difficulties with sucking and swallowing, and/or latching onto the ...
... babies described as ‘failure to thrive’. This term is used to describe a baby who has poor weight gain and physical growth failure over a period of time. The hypotonia that is common in babies with a 22q12/13 duplication can lead to difficulties with sucking and swallowing, and/or latching onto the ...
BIO 402 - National Open University of Nigeria
... The beginning of cytogenetics and of the chromosome theory of inheritance were clearly outlined by Wilson’s statement that the visible chromomeres on the chromosomes were in all probability much larger than the ultimate dividing units and that these units must be capable of assimilation, growth, and ...
... The beginning of cytogenetics and of the chromosome theory of inheritance were clearly outlined by Wilson’s statement that the visible chromomeres on the chromosomes were in all probability much larger than the ultimate dividing units and that these units must be capable of assimilation, growth, and ...
1 - IPPC
... indicated in Figures 1 and 2 are the minimum requirements for the diagnosis, but further tests may be required by the national plant protection organization (NPPO), especially for the first report in a country. For example, serological tests may facilitate a presumptive diagnosis of symptomatic plan ...
... indicated in Figures 1 and 2 are the minimum requirements for the diagnosis, but further tests may be required by the national plant protection organization (NPPO), especially for the first report in a country. For example, serological tests may facilitate a presumptive diagnosis of symptomatic plan ...
WOTD - Brookwood High School
... neither allele is dominant to the other, both are expressed equally, often a blending of the two traits occurs ...
... neither allele is dominant to the other, both are expressed equally, often a blending of the two traits occurs ...
Mutagen
In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens. Not all mutations are caused by mutagens: so-called ""spontaneous mutations"" occur due to spontaneous hydrolysis, errors in DNA replication, repair and recombination.