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Name
Name

... 33. Probes are small pieces of DNA that are radioactive. How do they attach themselves to the fragments on the nylon sheet? ...
Oppenheimer ABT 9101
Oppenheimer ABT 9101

... their action remains uncertain. In recent years indirect evidence has accumulated that suggested that these carcinogens act at the DNA level, altering or activating certain genes to form oncogenes (cancer causing genes), that can produce protein products that lead to the malignant transformation of ...
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... amino acid glycine for an arginine at codon 1529 (p.Gly1529Arg). This sequence change has previously been reported as an unclassified variant on the BIC database. A report by Chen et al. (J. Biol.Chem., 274, 32931) has shown that this sequence change reduces RAD51 binding activity. It may not be app ...
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Unit 8b-Modern Genetics
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Mutagen



In genetics, a mutagen is a physical or chemical agent that changes the genetic material, usually DNA, of an organism and thus increases the frequency of mutations above the natural background level. As many mutations can cause cancer, mutagens are therefore also likely to be carcinogens. Not all mutations are caused by mutagens: so-called ""spontaneous mutations"" occur due to spontaneous hydrolysis, errors in DNA replication, repair and recombination.
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